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1. 发明申请

US20050219527A1 Sample analyzer and computer program product 有权
标题翻译：样品分析仪和计算机程序产品
公开(公告)号：US20050219527A1
公开(公告)日：2005-10-06
申请号：US11076048
申请日：2005-03-10
申请人： Yoshiro Ikeuchi , Shinichiro Oguni , Daigo Fukuma , Masanori Imazu , Jo Linssen
发明人： Yoshiro Ikeuchi , Shinichiro Oguni , Daigo Fukuma , Masanori Imazu , Jo Linssen
IPC分类号： G01N21/64 , G01N15/14 , G01N21/47 , G01N33/49 , G01N33/72 , G01N21/00
CPC分类号： G01N15/1459 , G01N2015/1006 , G01N2015/1402 , G01N2015/1477 , Y10T436/101666
摘要： A sample analyzer including a detection unit for irradiating a biological sample with light and obtaining optical information; a cell classification processor for classifying cells contained in the biological sample into cell groups based on the optical information; a scattered light information obtaining processor for obtaining scattered light information relating to a cell included in a predetermined cell group; a calculation processor for calculating a component value corresponding to an amount of component contained in cell included in the predetermined cell group based on the scattered light information; and an output device for outputting the component value calculated by the calculation means is disclosed. A computer program product is also disclosed.
摘要翻译：一种样本分析器，包括用于用光照射生物样品并获得光学信息的检测单元; 细胞分类处理器，用于基于所述光学信息将所述生物样品中包含的细胞分类成细胞组; 散射光信息获取处理器，用于获得与包括在预定单元组中的单元有关的散射光信息; 计算处理器，用于基于散射光信息计算与包含在所述预定单元组中的单元中包含的分量的量相对应的分量值; 并且公开了一种用于输出由计算装置计算出的分量值的输出装置。还公开了一种计算机程序产品。

2. 发明授权

US09116093B2 Blood analyzer, blood analysis method, and computer program product 有权
标题翻译：血液分析仪，血液分析方法和计算机程序产品
公开(公告)号：US09116093B2
公开(公告)日：2015-08-25
申请号：US13462236
申请日：2012-05-02
申请人： Masaki Abe , Ayumu Yoshida , Jo Linssen
发明人： Masaki Abe , Ayumu Yoshida , Jo Linssen
IPC分类号： G01N15/14 , G01N35/02 , G01N21/51 , G01N21/47 , G01N21/64 , G01N15/10 , G01N35/04
CPC分类号： G01N15/1459 , G01N21/51 , G01N35/026 , G01N2015/1006 , G01N2021/4707 , G01N2021/4726 , G01N2021/6441 , G01N2035/0415
摘要： A blood analyzer, a blood analysis method, and a computer program product that can distinguishably detect abnormal lymphocytes, blasts, and atypical lymphocytes are provided. A blood analyzer prepares a first measurement sample from a first reagent containing a hemolyzing agent, a second reagent containing a fluorescence staining dye, and the blood specimen, and prepares a second measurement sample from a third reagent containing a hemolyzing agent, a fourth reagent containing a fluorescence staining dye, and the blood specimen. The blood analyzer measures each of the measurement samples, and distinguishably detects abnormal lymphocytes, blasts, and atypical lymphocytes in a blood specimen based on the measurement data.
摘要翻译：提供了可以区分地检测异常淋巴细胞，母细胞和非典型淋巴细胞的血液分析仪，血液分析方法和计算机程序产品。血液分析仪从含有溶血剂的第一试剂，含有荧光染色染料的第二试剂和血液样本制备第一测量样品，并从含有溶血剂的第三试剂制备第二测量样品，第四试剂含有荧光染色染料和血液标本。血液分析仪测量每个测量样品，并且基于测量数据可区分地检测血液样本中的异常淋巴细胞，母细胞和非典型淋巴细胞。

3. 发明申请

US20110166794A1 BLOOD CELL COUNTER, DIAGNOSIS SUPPORT APPARATUS, DIAGNOSIS SUPPORT METHOD AND COMPUTER PROGRAM PRODUCT 审中-公开
标题翻译：血细胞计数器，诊断支持装置，诊断支持方法和计算机程序产品
公开(公告)号：US20110166794A1
公开(公告)日：2011-07-07
申请号：US12888821
申请日：2010-09-23
申请人： Jo Linssen , Michael Schaefer
发明人： Jo Linssen , Michael Schaefer
IPC分类号： G01N33/49 , G06F19/00
CPC分类号： G01N15/147 , G01N2015/008 , G01N2015/0084 , G01N2015/1062 , G01N2015/1272
摘要： A blood cell counter comprising: a detector for detecting blood cells in blood of a subject; and a controller for obtaining, based on a detection result by the detector, first analytical information about hemoglobin amount of red blood cells in the blood and second analytical information about granulocytes in the blood, and for outputting diagnosis support information for supporting determination of whether an inflammatory response of the subject is an infectious inflammatory response or a noninfectious inflammatory response, based on the first analytical information and the second analytical information that have been obtained. A method and computer program product are also disclosed.
摘要翻译：一种血细胞计数器，包括：用于检测受试者血液中的血细胞的检测器; 以及控制器，用于根据检测器的检测结果获得关于血液中血红蛋白量的第一分析信息和关于血液中的粒细胞的第二分析信息，以及用于输出诊断支持信息，以确定是否基于获得的第一分析信息和第二分析信息，受试者的炎症反应是感染性炎症反应或非感染性炎症反应。还公开了一种方法和计算机程序产品。

4. 发明申请

US20080199947A1 Blood cell analyzer, blood cell analyzing method, and computer program product 有权
标题翻译：血细胞分析仪，血细胞分析法，计算机程序产品
公开(公告)号：US20080199947A1
公开(公告)日：2008-08-21
申请号：US12002973
申请日：2007-12-19
申请人： Jo Linssen , Hans Kalkman
发明人： Jo Linssen , Hans Kalkman
IPC分类号： C12M1/00 , G06G7/48
CPC分类号： G01N15/12 , G01N15/1459 , G01N2015/1477 , G01N2015/1486
摘要： A blood cell analyzer is provided with a first detection unit for electrically detecting blood cells in blood sample; a second detection unit for optically detecting blood cells in blood sample; a volume information obtainer for obtaining volume information of red blood cells based on the electrically detected blood cells; a scattered light intensity information obtainer for obtaining a scattered light intensity of red blood cells based on the optically detected blood cells; a first histogram preparer for preparing a first histogram of the volume information of each of red blood cells; a second histogram preparer for preparing a second histogram of the scattered light intensity information of each of red blood cells; a display unit; and a data processor for preparing a screen for displaying on the display unit, the screen including the first and second histograms.
摘要翻译：血细胞分析装置具有用于电检测血液样本中的血细胞的第一检测单元; 用于光学检测血液样本中的血细胞的第二检测单元; 体积信息获取器，用于基于电检测的血细胞获得红细胞的体积信息; 散射光强度信息获取器，用于基于光学检测的血细胞获得红细胞的散射光强度; 用于准备每个红细胞的体积信息的第一直方图的第一直方图准备器; 第二直方图准备器，用于准备每个红细胞的散射光强度信息的第二直方图; 显示单元; 以及数据处理器，用于准备用于在所述显示单元上显示的屏幕，所述屏幕包括所述第一和第二直方图。

5. 发明申请

US20080024759A1 SAMPLE ANALYZER AND COMPUTER PROGRAM PRODUCT 有权
标题翻译：样品分析仪和计算机程序产品
公开(公告)号：US20080024759A1
公开(公告)日：2008-01-31
申请号：US11844522
申请日：2007-08-24
申请人： Yoshiro IKEUCHI , Shinichiro Oguni , Daigo Fukuma , Masanori Imazu , Jo Linssen
发明人： Yoshiro IKEUCHI , Shinichiro Oguni , Daigo Fukuma , Masanori Imazu , Jo Linssen
IPC分类号： G01N33/48 , G01N21/49 , G01R31/00
CPC分类号： G01N15/1459 , G01N2015/1006 , G01N2015/1402 , G01N2015/1477 , Y10T436/101666
摘要： A sample analyzer including a detection unit for irradiating a biological sample with light and obtaining optical information; a cell classification processor for classifying cells contained in the biological sample into cell groups based on the optical information; a scattered light information obtaining processor for obtaining scattered light information relating to a cell included in a predetermined cell group; a calculation processor for calculating a component value corresponding to an amount of component contained in cell included in the predetermined cell group based on the scattered light information; and an output device for outputting the component value calculated by the calculation means is disclosed. A computer program product is also disclosed.
摘要翻译：一种样本分析器，包括用于用光照射生物样品并获得光学信息的检测单元; 细胞分类处理器，用于基于所述光学信息将所述生物样品中包含的细胞分类成细胞组; 散射光信息获取处理器，用于获得与包括在预定单元组中的单元有关的散射光信息; 计算处理器，用于基于散射光信息计算与包含在所述预定单元组中的单元中包含的分量的量相对应的分量值; 并且公开了一种用于输出由计算装置计算出的分量值的输出装置。还公开了一种计算机程序产品。

6. 发明授权

US07283217B2 Sample analyzer and computer product 有权
标题翻译：样品分析仪和计算机产品
公开(公告)号：US07283217B2
公开(公告)日：2007-10-16
申请号：US11076048
申请日：2005-03-10
申请人： Yoshiro Ikeuchi , Shinichiro Oguni , Daigo Fukuma , Masanori Imazu , Jo Linssen
发明人： Yoshiro Ikeuchi , Shinichiro Oguni , Daigo Fukuma , Masanori Imazu , Jo Linssen
IPC分类号： G01N33/48 , G01N31/00 , G01N33/72
CPC分类号： G01N15/1459 , G01N2015/1006 , G01N2015/1402 , G01N2015/1477 , Y10T436/101666
摘要： A sample analyzer including a detection unit for irradiating a biological sample with light and obtaining optical information; a cell classification processor for classifying cells contained in the biological sample into cell groups based on the optical information; a scattered light information obtaining processor for obtaining scattered light information relating to a cell included in a predetermined cell group; a calculation processor for calculating a component value corresponding to an amount of component contained in cell included in the predetermined cell group based on the scattered light information; and an output device for outputting the component value calculated by the calculation means is disclosed. A computer program product is also disclosed.
摘要翻译：一种样本分析器，包括用于用光照射生物样品并获得光学信息的检测单元; 细胞分类处理器，用于基于所述光学信息将所述生物样品中包含的细胞分类成细胞组; 散射光信息获取处理器，用于获得与包括在预定单元组中的单元有关的散射光信息; 计算处理器，用于基于散射光信息计算与包含在所述预定单元组中的单元中包含的分量的量相对应的分量值; 并且公开了一种用于输出由计算装置计算出的分量值的输出装置。还公开了一种计算机程序产品。

7. 发明授权

US08808623B2 Diagnosis assisting system, diagnosis assisting information providing device and computer program product 有权
标题翻译：诊断辅助系统，诊断辅助信息提供装置和计算机程序产品
公开(公告)号：US08808623B2
公开(公告)日：2014-08-19
申请号：US12180999
申请日：2008-07-28
申请人： Jo Linssen , Matthias Guhl
发明人： Jo Linssen , Matthias Guhl
IPC分类号： G01N21/00 , G06F19/00 , G06Q50/24 , G01N35/00
CPC分类号： G01N35/00722 , G01N15/12 , G01N15/1459 , G01N35/00594 , G01N35/00871 , G01N2015/1006 , G01N2035/00881 , G01N2035/009 , G06F19/00 , G06F19/324 , G06Q50/24 , G16H15/00 , Y10T436/11 , Y10T436/111666 , Y10T436/112499 , Y10T436/113332
摘要： A diagnosis assisting system comprising: an analyzing section for analyzing a sample collected from a subject; a determining section for determining whether there is a possibility that a subject has a predetermined disease based on an analysis result obtained by the analyzing section; a notification section for notifying the possibility when the determining section has determined that there is the possibility; and a diagnosis assisting information display section for displaying a diagnosis assisting information screen which displays diagnosis assisting information related to the predetermined disease, is disclosed. A diagnosis assisting information providing device and a computer program product are also disclosed.
摘要翻译：一种诊断辅助系统，包括：用于分析从受试者收集的样本的分析部分; 确定部，用于基于由所述分析部获得的分析结果来确定是否存在具有预定疾病的可能性; 通知部，用于在判定部判断为有可能的情况下通知可能性; 以及诊断辅助信息显示部分，用于显示显示与预定疾病相关的诊断辅助信息的诊断辅助信息屏幕。还公开了诊断辅助信息提供装置和计算机程序产品。

8. 发明申请

US20120282601A1 BLOOD ANALYZER, BLOOD ANALYSIS METHOD, AND COMPUTER PROGRAM PRODUCT 有权
标题翻译：血液分析仪，血液分析方法和计算机程序产品
公开(公告)号：US20120282601A1
公开(公告)日：2012-11-08
申请号：US13462236
申请日：2012-05-02
申请人： Masaki Abe , Ayumu Yoshida , Jo Linssen
发明人： Masaki Abe , Ayumu Yoshida , Jo Linssen
IPC分类号： G01N21/64 , C12M1/34
CPC分类号： G01N15/1459 , G01N21/51 , G01N35/026 , G01N2015/1006 , G01N2021/4707 , G01N2021/4726 , G01N2021/6441 , G01N2035/0415
摘要： A blood analyzer, a blood analysis method, and a computer program product that can distinguishably detect abnormal lymphocytes, blasts, and atypical lymphocytes are provided. A blood analyzer prepares a first measurement sample from a first reagent containing a hemolyzing agent, a second reagent containing a fluorescence staining dye, and the blood specimen, and prepares a second measurement sample from a third reagent containing a hemolyzing agent, a fourth reagent containing a fluorescence staining dye, and the blood specimen. The blood analyzer measures each of the measurement samples, and distinguishably detects abnormal lymphocytes, blasts, and atypical lymphocytes in a blood specimen based on the measurement data.
摘要翻译：提供了可以区分地检测异常淋巴细胞，母细胞和非典型淋巴细胞的血液分析仪，血液分析方法和计算机程序产品。血液分析仪从含有溶血剂的第一试剂，含有荧光染色染料的第二试剂和血液样本制备第一测量样品，并从含有溶血剂的第三试剂制备第二测量样品，第四试剂含有荧光染色染料和血液标本。血液分析仪测量每个测量样品，并且基于测量数据可区分地检测血液样本中的异常淋巴细胞，母细胞和非典型淋巴细胞。

9. 发明申请

US20110077870A1 BLOOD CELL COUNTER, DIAGNOSIS SUPPORT METHOD AND COMPUTER PROGRAM PRODUCT 审中-公开
标题翻译：血细胞计数器，诊断支持方法和计算机程序产品
公开(公告)号：US20110077870A1
公开(公告)日：2011-03-31
申请号：US12888844
申请日：2010-09-23
申请人： Jo Linssen , Michael Schaefer
发明人： Jo Linssen , Michael Schaefer
IPC分类号： G06F19/00 , C12M1/34
CPC分类号： G01N15/147 , G01N2015/008 , G01N2015/0084 , G01N2015/1062 , G01N2015/1272
摘要： A blood cell counter apparatus comprising: a detector for detecting blood cells in blood of a subject; and a controller for obtaining, based on a detection result by the detector, first analytical information about nucleated red blood cells in the blood, and second analytical information about granulocytes in the blood or third analytical information about platelets in the blood, and for outputting diagnosis support information for supporting prognosis of the subject, based on the first analytical information and on the second analytical information or the third analytical information that have been obtained. A method and computer program product are also disclosed.
摘要翻译：一种血细胞计数器装置，包括：检测器，用于检测受试者的血液中的血细胞; 以及控制器，用于基于检测器的检测结果获得关于血液中的有核红细胞的第一分析信息和关于血液中的粒细胞的第二分析信息或关于血液中血小板的第三分析信息，以及用于输出诊断根据第一个分析信息和第二个分析信息或第三个分析信息，支持信息，支持该主题的预后。还公开了一种方法和计算机程序产品。

10. 发明申请

US20080268494A1 HEMATOLOGY ANALYZER, HEMATOLOGY ANALYZING METHOD, AND COMPUTER PROGRAM PRODUCT 审中-公开
标题翻译：血液分析仪，血液分析方法和计算机程序产品
公开(公告)号：US20080268494A1
公开(公告)日：2008-10-30
申请号：US12044780
申请日：2008-03-07
申请人： Jo Linssen
发明人： Jo Linssen
IPC分类号： C12Q1/06 , C12M1/34
CPC分类号： G01N15/1459 , G01N15/12 , G01N33/491 , G01N2015/0073 , G01N2015/0076 , G01N2015/0084 , G01N2015/1037 , G01N2015/1477
摘要： A hematology analyzer, obtains red blood cell scattered light information which is scattered light information related to red blood cells contained in a blood sample and reticulocyte scattered light information which is scattered light information related to reticulocytes contained in the blood sample; obtains a value equivalent to the amount of hemoglobin in the red blood cells from the red blood cell scattered light information; obtains a value equivalent to the amount of hemoglobin in the reticulocytes from the reticulocyte scattered light information; obtains difference between the hemoglobin amounts which is the difference between the value equivalent to the amount of hemoglobin in the red blood cells and the value equivalent to the amount of hemoglobin in the reticulocytes; and obtains information supporting clinical examination based on the value equivalent to the amount of hemoglobin in the reticulocytes and the difference between the hemoglobin amounts, is disclosed. A hematology analyzing method and a computer program product are also disclosed.
摘要翻译：血液分析仪得到与血液样本中含有的红细胞有关的散射光信息的红细胞散射光信息和与血液样本中所含的网织红细胞有关的散射光信息的网织红细胞散射光信息，从红细胞散射光信息获得与红细胞中的血红蛋白量相当的值; 从网织红细胞散射光信息获得与网织红细胞中血红蛋白量相当的值; 获得血红蛋白量之间的差异，该血红蛋白量是与红细胞中血红蛋白量相当的值和与网织红细胞中的血红蛋白量相当的值之差; 并且基于与网织红细胞中的血红蛋白量相当的值和血红蛋白量之间的差异获得支持临床检查的信息。还公开了血液学分析方法和计算机程序产品。

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