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1. 发明授权

US09605043B2 Fusion protein for suppressing cancer cell growth and suppressing vasculogenesis, and anticancer composition comprising same 有权
公开(公告)号：US09605043B2
公开(公告)日：2017-03-28
申请号：US14125021
申请日：2012-06-08
申请人： Hyo Jeong Hong , Rohit Singh
发明人： Hyo Jeong Hong , Rohit Singh
IPC分类号： A61K38/18 , C07K14/71 , C07K14/475 , C07K16/28 , C07K16/32 , C07K14/52 , A61K38/17 , A61K39/00 , A61K38/00
CPC分类号： C07K14/475 , A61K38/00 , A61K38/179 , A61K2039/505 , C07K14/52 , C07K16/2863 , C07K16/32 , C07K2317/24 , C07K2317/622 , C07K2317/73 , C07K2319/30 , C07K2319/32 , A61K2300/00
摘要： The present invention relates to a fusion protein resulting from the fusion of a cancer-specific antibody and an angiogenesis inhibitor, and relates to an anti-cancer composition including the same. More specifically, in the present invention, it is preferable that the cancer-specific antibody is trastuzumab or a fragment thereof, and the angiogenesis inhibitor is a VEGF-Trap. When the fusion protein according to the present invention is used, there are advantages in that angiogenesis and cancer cell growth can be effectively inhibited as compared to trastuzumab or VEGF-Trap, and side effects can also be reduced.

2. 发明授权

US08114696B2 CMOS image sensor with asymmetric well structure of source follower 有权
标题翻译： CMOS图像传感器具有不对称阱结构的源极跟随器
公开(公告)号：US08114696B2
公开(公告)日：2012-02-14
申请号：US12970466
申请日：2010-12-16
申请人： Hee-Jeong Hong
发明人： Hee-Jeong Hong
IPC分类号： H01L21/00
CPC分类号： H01L31/0352 , H01L27/14601 , H01L27/14643
摘要： Provided is a CMOS image sensor with an asymmetric well structure of a source follower. The CMOS image sensor includes: a well disposed in an active region of a substrate; a drive transistor having one terminal connected to a power voltage and a first gate electrode disposed to cross the well; and a select transistor having a drain-source junction between another terminal of the drive transistor and an output node, and a second gate electrode disposed in parallel to the drive transistor. A drain region of the drive transistor and a source region of the select transistor are asymmetrically arranged.
摘要翻译：提供了具有源极跟随器的不对称阱结构的CMOS图像传感器。 CMOS图像传感器包括：阱，其设置在衬底的有源区域中; 具有连接到电源电压的一个端子和设置成跨越阱的第一栅电极的驱动晶体管; 以及在驱动晶体管的另一个端子和输出节点之间具有漏极 - 源极结的选择晶体管和与驱动晶体管并联设置的第二栅电极。驱动晶体管的漏极区域和选择晶体管的源极区域不对称地布置。

3. 发明申请

US20110071107A1 USES OF WATER-SOLUBLE CELLULOSE DERIVATIVES FOR PREVENTING OR TREATING METABOLIC SYNDROME 审中-公开
标题翻译：用于预防或治疗代谢综合征的水溶性纤维素衍生物的使用
公开(公告)号：US20110071107A1
公开(公告)日：2011-03-24
申请号：US12446366
申请日：2007-10-18
申请人： Stephanie K Lynch , Maciej Turowski , Wallace Yokoyama , Yun-Jeong Hong , Jerry R. Conklin , Shao-Ching Hung , Scott A. Young
发明人： Stephanie K Lynch , Maciej Turowski , Wallace Yokoyama , Yun-Jeong Hong , Jerry R. Conklin , Shao-Ching Hung , Scott A. Young
IPC分类号： A61K31/717 , A61P3/00 , A61P9/12 , A61P29/00
CPC分类号： A61K31/717
摘要： Water-soluble cellulose derivatives are useful in methods of preventing or treating metabolic syndrome or a symptom or condition associated with the metabolic syndrome in an individual, and in particular for preventing or treating one or more of the symptoms a) hypertension, b) proinflammatory or inflammation state and c) prothrombotic state.
摘要翻译：水溶性纤维素衍生物可用于预防或治疗代谢综合征或与个体代谢综合征有关的症状或病症的方法，特别是用于预防或治疗一种或多种症状a）高血压，b）促炎症或炎症状态和c）血栓前状态。

4. 发明授权

US07688492B2 Laser processing apparatus 有权
标题翻译：激光加工设备
公开(公告)号：US07688492B2
公开(公告)日：2010-03-30
申请号：US11578373
申请日：2004-06-02
申请人： You-Hi Han , Eun-Jeong Hong , Hak-Yong Lee , Won-Chul Jung
发明人： You-Hi Han , Eun-Jeong Hong , Hak-Yong Lee , Won-Chul Jung
IPC分类号： G02B26/08
CPC分类号： B23K26/083 , B23K26/066 , B23K26/0736 , B23K26/082 , H01L21/78
摘要： Disclosed is a laser processing apparatus for minimizing generation of sludge and enhancing the processing efficiency while processing an object. The laser processing apparatus includes a beam irradiator for emitting a laser beam from a laser light source, a beam scanner for operating the laser beam emitted from the beam scanner, to be irradiated on a predetermined interval of a processing position of the object repeatedly on the straight, and a condensing lens for regulating a focus of the laser beam emitted from the beam irradiator. The object is movable at least once along a processing direction during processing the object. According to the present invention, it is able to improve the processing efficiency and to work an object with a uniform morphology by using a mask filtering a laser beam irradiated at a rotation turning point of a beam scanning mirror, capable of continuously irradiating a laser beam by deforming the laser beam into an elliptical pattern.
摘要翻译：公开了一种用于在处理物体的同时最小化污泥的产生和提高处理效率的激光加工装置。激光加工装置包括用于从激光源发射激光束的光束照射器，用于操作从光束扫描器发射的激光束的光束扫描器，以在物体的反复处理位置的预定间隔上照射以及用于调节从光束照射器发射的激光束的焦点的聚光透镜。该物体在处理物体期间沿着处理方向可移动至少一次。根据本发明，通过使用照射在光束扫描镜的旋转转折点处的激光束进行掩模过滤，能够提高处理效率并且对具有均匀形态的物体进行加工，能够连续照射激光束通过使激光束变形为椭圆形图案。

5. 发明申请

US20090093442A1 USES OF WATER-SOLUBLE CELLULOSE DERIVATIVES FOR PREVENTING OR TREATING METABOLIC SYNDROME 审中-公开
标题翻译：用于预防或治疗代谢综合征的水溶性纤维素衍生物的使用
公开(公告)号：US20090093442A1
公开(公告)日：2009-04-09
申请号：US11874671
申请日：2007-10-18
申请人： Stephanie K. Lynch , Maciej Turowski , Wallace Yokoyama , Yun-Jeong Hong , Jerry R. Conklin , Shao-Ching Hung , Scott A. Young
发明人： Stephanie K. Lynch , Maciej Turowski , Wallace Yokoyama , Yun-Jeong Hong , Jerry R. Conklin , Shao-Ching Hung , Scott A. Young
IPC分类号： A61K31/717 , A61P9/12 , A61P9/00 , A61P29/00
CPC分类号： A61K31/717
摘要： Water-soluble cellulose derivatives are useful in methods of preventing or treating metabolic syndrome or a symptom or condition associated with the metabolic syndrome in an individual, and in particular for preventing or treating one or more of the symptoms a) hypertension, b) proinflammatory or inflammation state and c) prothrombotic state.
摘要翻译：水溶性纤维素衍生物可用于预防或治疗代谢综合征或与个体代谢综合征有关的症状或病症的方法，特别是用于预防或治疗一种或多种症状a）高血压，b）促炎症或炎症状态和c）血栓前状态。

6. 发明申请

US20080088900A1 Laser Processing Apparatus 有权
标题翻译：激光加工设备
公开(公告)号：US20080088900A1
公开(公告)日：2008-04-17
申请号：US11578373
申请日：2004-06-02
申请人： Han Hie , Eun Jeong Hong , Hak Yong Lee , Won Chul Jung
发明人： Han Hie , Eun Jeong Hong , Hak Yong Lee , Won Chul Jung
IPC分类号： H01L21/78
CPC分类号： B23K26/083 , B23K26/066 , B23K26/0736 , B23K26/082 , H01L21/78
摘要： Disclosed is a laser processing apparatus for minimizing generation of sludge and enhancing the processing efficiency while processing an object. The laser processing apparatus includes a beam irradiator for emitting a laser beam from a laser light source, a beam scanner for operating the laser beam emitted from the beam scanner, to be irradiated on a predetermined interval of a processing position of the object repeatedly on the straight, and a condensing lens for regulating a focus of the laser beam emitted from the beam irradiator The object is movable at least once along a processing direction during processing the object. According to the present invention, it is able to improve the processing efficiency and to work an object with a uniform morphology by using a mask filtering a laser beam irradiated at a rotation turning point of a beam scanning mirror, capable of continuously irradiating a laser beam by deforming the laser beam into an elliptical pattern.
摘要翻译：公开了一种用于在处理物体的同时最小化污泥的产生和提高处理效率的激光加工装置。激光加工装置包括用于从激光源发射激光束的光束照射器，用于操作从光束扫描器发射的激光束的光束扫描器，以在物体的反复处理位置的预定间隔上照射直线和用于调节从光束照射器发射的激光束的焦点的聚光透镜该物体在处理物体期间沿着处理方向可移动至少一次。根据本发明，通过使用照射在光束扫描镜的旋转转折点处的激光束进行掩模过滤，能够提高处理效率并且对具有均匀形态的物体进行加工，能够连续照射激光束通过使激光束变形为椭圆形图案。

7. 发明申请

US20080076234A1 Method of multi-processing object using polygon mirror 有权
标题翻译：使用多面镜的多处理对象的方法
公开(公告)号：US20080076234A1
公开(公告)日：2008-03-27
申请号：US11902602
申请日：2007-09-24
申请人： Eun Jeong Hong , Hak Yong Lee , Tae Kyoung Ryoo
发明人： Eun Jeong Hong , Hak Yong Lee , Tae Kyoung Ryoo
IPC分类号： H01L21/78 , B23K26/40
CPC分类号： B23K26/082 , B23K26/0821 , B23K26/40 , B23K2103/172
摘要： A method of multi-processing an object using a polygon mirror according to an embodiment of the invention includes setting processing parameters for individual layers of an object having a multilayer structure, performing laser processing on exposed layers in a region to be processed of the object according to the processing parameters using a polygon mirror, determining whether or not all of the layers of the object having a multilayer structure are processed, and if it is determined in the determining that not all of the layers are processed, progressing the performing of laser processing. Therefore, efficiency in processing the object can be increased, and cracks that occur in the object during laser processing using a polygon mirror can be minimized.
摘要翻译：根据本发明的实施例的使用多面镜对物体进行多处理的方法包括设置具有多层结构的物体的各层的处理参数，对待处理的物体的区域中的暴露层进行激光处理，涉及使用多面镜的处理参数，确定是否处理具有多层结构的对象的所有层，并且如果确定不是所有的层都被处理，则进行激光加工的执行。因此，能够提高加工对象物的效率，能够使使用多面镜的激光加工时的物体发生的裂缝最小化。

8. 发明申请

US20060157746A1 CMOS image sensor with asymmetric well structure of source follower 有权
公开(公告)号：US20060157746A1
公开(公告)日：2006-07-20
申请号：US11319560
申请日：2005-12-29
申请人： Hee-Jeong Hong
发明人： Hee-Jeong Hong
IPC分类号： H01L29/80
CPC分类号： H01L31/0352 , H01L27/14601 , H01L27/14643
摘要： Provided is a CMOS image sensor with an asymmetric well structure of a source follower. The CMOS image sensor includes: a well disposed in an active region of a substrate; a drive transistor having one terminal connected to a power voltage and a first gate electrode disposed to cross the well; and a select transistor having a drain-source junction between another terminal of the drive transistor and an output node, and a second gate electrode disposed in parallel to the drive transistor. A drain region of the drive transistor and a source region of the select transistor are asymmetrically arranged.

9. 发明申请

US20060039057A1 Laser processing apparatus and method using polygon mirror 有权
标题翻译：激光加工设备和使用多面镜的方法
公开(公告)号：US20060039057A1
公开(公告)日：2006-02-23
申请号：US10982091
申请日：2004-11-04
申请人： You-Hie Han , Eun-Jeong Hong
发明人： You-Hie Han , Eun-Jeong Hong
IPC分类号： G02B26/08
CPC分类号： B23K26/0736 , B23K26/082 , B23K26/0821 , B23K26/40 , B23K2101/40 , B23K2103/42 , B23K2103/50
摘要： Disclosed is a laser processing apparatus and method for enhancing processing efficiency of an object by means of a polygon mirror. The laser processing apparatus includes a laser generator outputting a laser beam with a predetermined diameter, a polygon mirror rotating on an axis with plural reflection planes to reflect the laser beam incident on the reflection planes from the laser generator, in which the number of the reflection planes is set in order that the laser beam can cover at least two reflection planes of the polygon mirror, and a lens condensing and irradiating the laser beam reflected from the polygon mirror. According to the present invention, it is able to improve the processing efficiency and product yield of an object by dividing the laser beam into the plurality to be incident on the reflection planes of the polygon mirror and repeatedly processing the object in low energy by means of the divided laser beam.
摘要翻译：公开了一种通过多面镜提高物体的处理效率的激光加工装置和方法。激光加工装置包括：输出具有预定直径的激光束的激光发生器，具有多个反射面的轴上旋转的多面镜，以反射入射到来自激光发生器的反射面上的激光束，其中反射次数设置平面以便激光束可以覆盖多面镜的至少两个反射面，以及聚焦并照射从多面镜反射的激光束的透镜。根据本发明，能够通过将激光束分割为多个入射到多面体反射镜的反射面上并以低能量重复地处理物体，从而提高物体的处理效率和产品产量，借助于分割的激光束。

10. 发明申请

US20050106096A1 Method for preparing of alpha-alumina nano powder 有权
标题翻译： α-氧化铝纳米粉末的制备方法
公开(公告)号：US20050106096A1
公开(公告)日：2005-05-19
申请号：US10469882
申请日：2003-01-03
申请人： Hye-Jeong Hong , Tae-Hyun Kwon , Seung-Beom Cho , Jun-Seok Nho , Dae-Gon Han
发明人： Hye-Jeong Hong , Tae-Hyun Kwon , Seung-Beom Cho , Jun-Seok Nho , Dae-Gon Han
IPC分类号： C01F7/02 , C01F7/30 , C01F7/36 , C09K3/14
CPC分类号： C01F7/448 , B82Y30/00 , C01F7/36 , C01P2004/03 , C01P2004/32 , C01P2004/52 , C01P2004/64 , C01P2006/80 , C09K3/1463 , Y10S977/775 , Y10S977/811
摘要： The present invention relates to a preparation method of α-alumina nano powder, and more particularly to a preparation method of α-alumina nano powder that has a uniform particle shape and size distribution, is capable of being produced at a low temperature, and contains less than 20 ppm of alkali metals such as Na and K. the α-alumina nano powder is prepared by glycolating aluminium alkoxide in glycol solution containing the α-iron oxide or α-alumina nucleation seed and carrying out glyco thermal reaction.
摘要翻译：本发明涉及α-氧化铝纳米粉末的制备方法，更具体地说涉及具有均匀的粒子形状和粒径分布的α-氧化铝纳米粉末的制备方法，其能够在低温下生产，并且含有低于20ppm的碱金属如Na和K.通过将含有α-氧化铁或α-氧化铝成核种子的二醇溶液中的烷醇铝醇化，并进行糖热反应来制备α-氧化铝纳米粉末。

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