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1. 发明授权

US10426554B2 System and method for tracking and navigation 有权
公开(公告)号：US10426554B2
公开(公告)日：2019-10-01
申请号：US14113563
申请日：2012-04-30
申请人： Jeffrey H. Siewerdsen , Yoshito Otake , Russell H. Taylor
发明人： Jeffrey H. Siewerdsen , Yoshito Otake , Russell H. Taylor
IPC分类号： A61B34/20 , A61B6/00 , A61N5/10 , A61B90/00
摘要： A tracking and navigation system is provided. The system includes an imaging or treatment device, a tracker device, and a fiducial marker. At least part of the imaging or treatment device is movable relative to a patient. The tracker device is mounted on the imaging or treatment device and is movable therewith relative to the patient. The fiducial marker may be fixed relative to the patient to define a patient coordinate system. The fiducial marker is detectable by the tracker device to substantially maintain registration between the tracker device and the patient coordinate system. A tracking and navigation kit including the tracker device and at least one fiducial marker may also be provided, for example, for retrofitting to existing imaging or treatment devices.

2. 发明授权

US08210745B2 Extremity imaging apparatus for cone beam computed tomography 有权
标题翻译：锥束计算机断层扫描的肢端成像装置
公开(公告)号：US08210745B2
公开(公告)日：2012-07-03
申请号：US13076705
申请日：2011-03-31
申请人： John Yorkston , William F. Snyder , Jeffrey H. Siewerdsen
发明人： John Yorkston , William F. Snyder , Jeffrey H. Siewerdsen
IPC分类号： H05G1/04
CPC分类号： A61B6/032 , A61B6/04 , A61B6/4085 , A61B6/4291 , A61B6/466 , A61B6/505
摘要： An apparatus for cone beam computed tomography of lower leg portions of a patient has a radiation source and a source transport actuable to move the source along an arcuate source path within a housing, from one side of a circumferential gap to the other and has a radius R2 about a center. A housing is provided for placement of the patient's foot. A digital radiation detector has a detector transport actuable to move the detector along an arcuate detector path within the housing, the detector path having a radius R1 about the center and concentric with the source path, wherein R1 is less than R2, and wherein the detector path extends from one side of the pedestal indent to the other. A gap closure apparatus is movable to a position that continues the detector path across the circumferential gap and encloses the detector path.
摘要翻译：用于患者的小腿部分的锥形束计算机断层摄影的装置具有可驱动的辐射源和源运送装置，其可沿着圆周间隙的另一侧沿壳体内的弧形源路径移动源，并具有半径 R2关于中心。提供用于放置患者脚的壳体。数字辐射检测器具有可操作的检测器传送装置，用于沿着壳体内的弓形检测器路径移动检测器，检测器路径具有围绕中心并且与源路径同心的半径R1，其中R1小于R2，并且其中检测器路径从基座缩进的一侧延伸到另一侧。间隙闭合装置可移动到使检测器路径跨过周向间隙继续并包围检测器路径的位置。

3. 发明申请

US20080198964A1 CARDIAC GATING FOR DUAL-ENERGY IMAGING 有权
公开(公告)号：US20080198964A1
公开(公告)日：2008-08-21
申请号：US11951483
申请日：2007-12-06
申请人： Richard L. VanMetter , Jeffrey H. Siewerdsen , Nick A. Shkumat , John Yorkston
发明人： Richard L. VanMetter , Jeffrey H. Siewerdsen , Nick A. Shkumat , John Yorkston
IPC分类号： A61B6/00
CPC分类号： A61B6/482 , A61B5/0261 , A61B5/1455 , A61B6/503 , A61B6/541
摘要： Methods are provided for cardiac gating of multiple-energy projection radiographic imaging utilizing an apparatus that measures the patient's peripheral blood perfusion. The choice of methods is dependant on the patient's heart rate and the delays inherent in the imaging system. A first method allows for imaging during the diastole period of the current cardiac cycle. A second method provides an implemented delay to acquire the image during the diastole period of a subsequent cardiac cycle. The use of the apparatus that measures the patient's peripheral blood perfusion allows for an efficient and convenient means of cardiac gating while avoiding occlusion of diagnostically important anatomy.
摘要翻译：提供了使用测量患者的外周血液灌注的装置的多能量投影放射成像心脏门控的方法。方法的选择取决于患者的心率和成像系统固有的延迟。第一种方法允许在当前心动周期的舒张期期间进行成像。第二种方法提供实施的延迟以在随后的心动周期的舒张期期间获取图像。测量患者外周血液灌注的装置的使用允许心脏门控的有效和方便的手段，同时避免了诊断上重要的解剖结构的闭塞。

4. 发明授权

US07356112B2 Computed tomography scanning 有权
标题翻译：计算机断层扫描
公开(公告)号：US07356112B2
公开(公告)日：2008-04-08
申请号：US11531471
申请日：2006-09-13
申请人： Kevin John Brown , David Jaffray , Jeffrey H. Siewerdsen , Marcel van Herk , Jan-Jakob Sonke
发明人： Kevin John Brown , David Jaffray , Jeffrey H. Siewerdsen , Marcel van Herk , Jan-Jakob Sonke
IPC分类号： G21N23/083
CPC分类号： G06T5/009 , A61N5/1064 , G06T5/003 , G06T7/0016 , G06T7/20 , G06T11/005 , G06T2207/10081 , G06T2207/20068 , G06T2207/20192 , G06T2207/30061 , G06T2207/30096 , G06T2211/412
摘要： Artifacts in the reconstructed volume data of cone beam CT systems can be removed by the application of respiration correlation techniques to the acquired projection images. To achieve this, the phase of the patients breathing is monitored while acquiring projection images continuously. On completion of the acquisition, projection images that have comparable breathing phases can be selected from the complete set, and these are used to reconstruct the volume data using similar techniques to those of conventional CT. Any phase can be selected and therefore the effect of breathing can be studied. It is also possible to use a feature in the projection images such as the patient's diaphragm to determine the breathing phase. This feature in the projection images can be used to control delivery of therapeutic radiation dependent on the patient's breathing cycle, to ensure that the tumor is in the correct position when the radiation is delivered.
摘要翻译：通过对所获取的投影图像应用呼吸相关技术，可以去除锥束CT系统的重建体数据中的伪像。为了实现这一点，在持续拍摄投影图像的同时监测患者呼吸的阶段。完成采集后，可以从完整组中选择具有相似呼吸相位的投影图像，并使用与常规CT类似的技术来重建体积数据。可以选择任何相位，因此可以研究呼吸的效果。也可以使用诸如患者隔膜的投影图像中的特征来确定呼吸阶段。投影图像中的该特征可以用于控制取决于患者呼吸周期的治疗辐射的传递，以确保当辐射被递送时肿瘤处于正确的位置。

5. 发明授权

US07349564B2 Imaging internal structures 有权
标题翻译：成像内部结构
公开(公告)号：US07349564B2
公开(公告)日：2008-03-25
申请号：US10760628
申请日：2004-01-20
申请人： Lambert Zijp , Kevin John Brown , David Jaffray , Jeffrey H. Siewerdsen , Marcel van Herk , Jan-Jakob Sonke
发明人： Lambert Zijp , Kevin John Brown , David Jaffray , Jeffrey H. Siewerdsen , Marcel van Herk , Jan-Jakob Sonke
IPC分类号： G06K9/00
CPC分类号： G06T5/009 , A61N5/1064 , G06T5/003 , G06T7/0016 , G06T7/20 , G06T11/005 , G06T2207/10081 , G06T2207/20068 , G06T2207/20192 , G06T2207/30061 , G06T2207/30096 , G06T2211/412
摘要： An apparatus, method and software module for selecting phase-correlated images from the output of a scanner such as a cone beam CT scanner operates by collapsing the images derived from the series from two dimensions to one dimension by summing the intensities of pixels along a dimension transverse to the one dimension, producing a further image from a composite of the one-dimensional images obtained from images in the series, analysing the further image for periodic patterns, and selecting from the series images having like phase in that periodic pattern. If desired, a plurality of reconstructions can be derived at different phases. The analysis of the further image for periodic patterns can include comparing the one-dimensional images therein, to identify a movement of features in that dimension. This allows (inter alia) the accurate determination of the breathing cycle in a patient and a concomitant improvement in the quality of CT scans by using phase-correlated images.
摘要翻译：用于从诸如锥形束CT扫描仪的扫描仪的输出中选择相位相关图像的装置，方法和软件模块通过将沿着维度的像素的强度相加而将从二维导出的图像从二维折叠到一维来进行操作横向于一个维度，从从该系列中的图像获得的一维图像的合成中产生另外的图像，分析另外的图像用于周期性图案，并从具有该周期性图案的类似相位的系列图像中进行选择。如果需要，可以在不同的阶段导出多个重建。对于周期性图案的另外的图像的分析可以包括比较其中的一维图像，以识别该维度中的特征的运动。这允许（特别地）通过使用相位相关图像来准确地确定患者的呼吸周期和伴随的CT扫描质量的改善。

6. 发明授权

US08998486B2 Extremity imaging apparatus for cone beam computed tomography 有权
标题翻译：锥束计算机断层扫描的肢端成像装置
公开(公告)号：US08998486B2
公开(公告)日：2015-04-07
申请号：US14266861
申请日：2014-05-01
申请人： John Yorkston , Robert J. Asento , Jeffrey H. Siewerdsen , David H. Foos
发明人： John Yorkston , Robert J. Asento , Jeffrey H. Siewerdsen , David H. Foos
IPC分类号： H05G1/04 , A61B6/03 , A61B6/04 , A61B6/00
CPC分类号： A61B6/035 , A61B6/03 , A61B6/032 , A61B6/04 , A61B6/4085 , A61B6/4441 , A61B6/4452 , A61B6/466 , A61B6/505
摘要： An apparatus for cone beam computed tomography of an extremity has a digital radiation detector and a first device to move the detector along a circular detector path extending so that the detector moves both at least partially around a first extremity of the patient and between the first extremity and a second, adjacent extremity. The detector path has radius R1 sufficient to position the extremity approximately centered in the detector path. There is a radiation source with a second device to move the source along a concentric circular source path having a radius R2 greater than radius R1, radius R2 sufficiently long to allow adequate radiation exposure of the first extremity for an image capture by the detector. A first circumferential gap in the source path allows the second extremity to be positioned in the first circumferential gap during image capture.
摘要翻译：用于末端锥形束计算机断层摄影的装置具有数字辐射检测器和第一装置，以沿着延伸的圆形检测器路径移动检测器，使得检测器至少部分地围绕患者的第一末端和第一末端之间移动和第二个相邻的肢体。检测器路径具有足够的半径R1，以使末端大致居中在检测器路径中。存在具有第二装置的辐射源，以沿着具有大于半径R1的半径R2，半径R2足够长的同心圆形源路径移动源，以允许第一末端的足够的辐射暴露用于检测器的图像捕获。源路径中的第一周向间隙允许在图像捕获期间将第二末端定位在第一周向间隙中。

7. 发明申请

US20140350387A1 ELECTROMAGNETIC TRACKING SYSTEM AND METHODS OF USING SAME 审中-公开
标题翻译：电磁跟踪系统及其使用方法
公开(公告)号：US20140350387A1
公开(公告)日：2014-11-27
申请号：US14117100
申请日：2012-05-11
申请人： Jeffrey H. Siewerdsen , Jongheun Yoo
发明人： Jeffrey H. Siewerdsen , Jongheun Yoo
IPC分类号： A61B6/04 , A61G13/04 , A61B5/06
CPC分类号： A61B6/0407 , A61B5/061 , A61B6/032 , A61B6/4085 , A61B6/4405 , A61B6/4423 , A61B6/4441 , A61B6/508 , A61B6/547 , A61B6/582 , A61B6/583 , A61B34/20 , A61B2034/2051 , A61G13/04 , A61G2200/322 , G01R33/028
摘要： An electromagnetic tracking system including a patient support element and an electromagnetic field generator. The patient support element is superposed relative to the electromagnetic field generator, and the electromagnetic field generator is selectively moveable relative to the patient support element.
摘要翻译：一种包括患者支撑元件和电磁场发生器的电磁跟踪系统。患者支撑元件相对于电磁场发生器叠加，并且电磁场发生器相对于患者支撑元件选择性地可移动。

8. 发明申请

US20140079338A1 METHOD AND SYSTEM FOR REGISTERING IMAGES 有权
标题翻译：用于注册图像的方法和系统
公开(公告)号：US20140079338A1
公开(公告)日：2014-03-20
申请号：US14117009
申请日：2012-05-14
申请人： Jeffrey H. Siewerdsen , Sajendra Nithiananthan , Daniel J. Mirota
发明人： Jeffrey H. Siewerdsen , Sajendra Nithiananthan , Daniel J. Mirota
IPC分类号： G06T3/00 , G06T11/60
CPC分类号： G06T3/0068 , A61B6/032 , A61B6/12 , A61B6/4085 , A61B6/506 , G06T7/0012 , G06T7/35 , G06T11/60 , G06T2207/10084 , G06T2207/20016
摘要： A system for registering images includes an image registration unit. The image registration unit is configured to receive first image data for a first image in an N-dimensional space, receive second image data for a second image in the N-dimensional space, calculate a field of update vectors that maps the first image into a moving image, and map the first image into the moving image using the field of update vectors such that the moving image more closely matches the second image. The field of update vectors includes a plurality of N+M dimensional update vectors, each update vector having N spatial components and M extra components. N is a number greater than zero, and M is a number greater than zero. The M extra components of the plurality of update vectors identify portions of the first image that are assigned external values during the mapping the first image into the moving image.
摘要翻译：用于记录图像的系统包括图像配准单元。图像注册单元被配置为接收N维空间中的第一图像的第一图像数据，在N维空间中接收第二图像的第二图像数据，计算将第一图像映射到运动图像，并且使用更新向量的领域将第一图像映射到运动图像中，使得运动图像与第二图像更匹配。更新向量的领域包括多个N + M维更新向量，每个更新向量具有N个空间分量和M个额外分量。 N是大于零的数字，M是大于零的数字。多个更新向量的M个额外分量识别在将第一图像映射到运动图像期间被分配外部值的第一图像的部分。

9. 发明申请

US20110176715A1 FOUR-DIMENSIONAL VOLUME IMAGING SYSTEM 审中-公开
标题翻译：四维体积成像系统
公开(公告)号：US20110176715A1
公开(公告)日：2011-07-21
申请号：US12971042
申请日：2010-12-17
申请人： David H. Foos , Jeffrey H. Siewerdsen , John Yorkston , Dong Yang
发明人： David H. Foos , Jeffrey H. Siewerdsen , John Yorkston , Dong Yang
IPC分类号： G06K9/00
CPC分类号： G06T11/006 , G06T2211/412 , G06T2211/436
摘要： A method for obtaining a 3-D image. An initial volume image is obtained of a subject wherein the subject is stationary and in a first pose. One or more 2-D images of the subject are obtained as the subject is moving between the first pose and a second pose. An endpoint volume image of the subject with the subject stationary and in the second pose is obtained. At least the initial volume image is modified according to the one or more obtained 2-D images to form at least one intermediate volume image that is representative of the subject's position between the first and second pose. The at least one intermediate volume image can be displayed.
摘要翻译：一种获得3-D图像的方法。获得对象的初始体积图像，其中对象是静止的并处于第一姿态。当对象在第一姿态和第二姿态之间移动时，获得被摄体的一个或多个2-D图像。获得被摄体静止并处于第二姿势的被摄体的端点体积图像。至少初始体积图像根据一个或多个所获得的2-D图像被修改以形成代表被摄体在第一和第二姿势之间的位置的至少一个中间体积图像。可以显示至少一个中间体积图像。

10. 发明授权

US07623628B2 Cardiac gating for dual-energy imaging 有权
标题翻译：心脏门控双能量成像
公开(公告)号：US07623628B2
公开(公告)日：2009-11-24
申请号：US11951483
申请日：2007-12-06
申请人： Richard L. VanMetter , Jeffrey H. Siewerdsen , Nick A. Shkumat , John Yorkston
发明人： Richard L. VanMetter , Jeffrey H. Siewerdsen , Nick A. Shkumat , John Yorkston
IPC分类号： A61B6/00
CPC分类号： A61B6/482 , A61B5/0261 , A61B5/1455 , A61B6/503 , A61B6/541
摘要： Methods are provided for cardiac gating of multiple-energy projection radiographic imaging utilizing an apparatus that measures the patient's peripheral blood perfusion. The choice of methods is dependant on the patient's heart rate and the delays inherent in the imaging system. A first method allows for imaging during the diastole period of the current cardiac cycle. A second method provides an implemented delay to acquire the image during the diastole period of a subsequent cardiac cycle. The use of the apparatus that measures the patient's peripheral blood perfusion allows for an efficient and convenient means of cardiac gating while avoiding occlusion of diagnostically important anatomy.
摘要翻译：提供了使用测量患者的外周血液灌注的装置的多能量投影放射成像心脏门控的方法。方法的选择取决于患者的心率和成像系统固有的延迟。第一种方法允许在当前心动周期的舒张期期间进行成像。第二种方法提供实施的延迟以在随后的心动周期的舒张期期间获取图像。测量患者外周血液灌注的装置的使用允许心脏门控的有效和方便的手段，同时避免了诊断上重要的解剖结构的闭塞。

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