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    • 7. 发明授权
    • Quantitative pulmonary imaging
    • 定量肺成像
    • US06915151B2
    • 2005-07-05
    • US10071434
    • 2002-02-08
    • James BaumgardnerDavid LipsonRahim RiziDavid RobertsMitchell Schnall
    • James BaumgardnerDavid LipsonRahim RiziDavid RobertsMitchell Schnall
    • G01R33/54A61B5/055
    • G01R33/5601
    • The present invention comprises imaging and quantitative measurement of lung ventilation, particularly in a human lung. Methods for quantitative imaging of lung ventilation, and the further provided systems and algorithmic tools therefore, comprise three primary components: the combined MRI ventilation/perfusion (V/Q) imaging techniques using hyperpolarized helium-3 (3He) gas (H3He); the three-dimensional quantitative imaging of absolute lung perfusion (Q) and collection of local magnetic resonance image data therefrom to produce an absolute lung perfusion image data; and the algorithmic co-registration of the two image data sets, (HP-3He MRI image of V/Q and MR imaging of quantitative perfusion (Q) in the lung). From the data acquired in the combined data sets and their spatial co-registration, absolute ventilation (V) is computed.
    • 本发明包括肺通气的成像和定量测量,特别是在人肺中。 肺通气定量成像的方法,以及进一步提供的系统和算法工具包括三个主要组成部分:使用超极化氦-3( 3)的组合MRI通气/灌注(V / Q)成像技术 He)气(H 3 H 3); 绝对肺灌注(Q)的三维定量成像和从其中收集局部磁共振图像数据产生绝对肺灌注图像数据; 以及两个图像数据集的算法共同配准(在HP中的V-Q的HP-3 He MRI图像和定量灌注(Q)的MR成像)。 根据组合数据集中获取的数据及其空间共同登记,计算绝对通气量(V)。