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    • 3. 发明申请
    • Novel oxazolidinone derivatives
    • 新型恶唑烷酮衍生物
    • US20070155798A1
    • 2007-07-05
    • US10596412
    • 2004-12-17
    • Jae RheeWeon ImChong ChoSung ChoiTae Lee
    • Jae RheeWeon ImChong ChoSung ChoiTae Lee
    • A61K31/4439C07D413/14
    • A61K31/4439A61K31/675C07D263/32C07D413/14C07D417/10C07D417/14C07F9/653C07F9/65583
    • The present invention relates to novel derivatives of oxazolidinone, a method thereof and pharmaceutical compositions comprising the derivatives for use in an antibiotic. The oxazolidinone derivatives of the present invention show inhibitory activity against a broad spectrum of bacteria and lower toxicity. The prodrugs, prepared by reacting the compound having hydroxyl group with amino acid or phosphate, have an excellent efficiency on solubility thereof against water. Further, the derivatives of the present invention may exert potent antibacterial activity versus various human and animal pathogens, including Gram-positive bacteria such as Staphylococi, Enterococci and Streptococi, anaerobic microorganisms such as Bacteroides and Clostridia, and acid-resistant microorganisms such as Mycobacterium tuberculosis and Mycobacterium avium. Accordingly, the compositions comprising the oxazolidinone are used in an antibiotic. Data supplied from the esp@cenet database—Worldwide
    • 本发明涉及恶唑烷酮的新衍生物,其方法和药物组合物,其包含用于抗生素的衍生物。 本发明的恶唑烷酮衍生物显示出对广谱细菌的抑制活性和较低的毒性。 通过使具有羟基的化合物与氨基酸或磷酸酯反应制备的前药在对水的溶解性方面具有优异的效果。 此外,本发明的衍生物可以相对于各种人和动物病原体,包括葡萄球菌,肠球菌和链球菌等革兰阳性菌,拟杆菌和梭菌等厌氧菌,耐结核菌如结核分枝杆菌 和鸟分枝杆菌。 因此,包含恶唑烷酮的组合​​物用于抗生素中。 从esp @ cenet database-Worldwide提供的数据
    • 6. 发明授权
    • Semiconductor memory devices and methods for sampling data therefrom based on a relative position of a memory cell array section containing the data
    • 半导体存储器件和方法,用于根据包含数据的存储单元阵列部分的相对位置对其数据进行采样
    • US06370068B2
    • 2002-04-09
    • US09755977
    • 2001-01-05
    • Sang-Jae Rhee
    • Sang-Jae Rhee
    • G11C722
    • G11C7/1057G11C7/1006G11C7/1012G11C7/1051
    • Semiconductor devices and methods of sampling data therefrom are provided in which data is sampled from a memory cell array based on a relative position of a memory cell array section that contains the data. A sense amplifier generates an output signal in response to an address of one or more cells in a memory cell array. A control circuit generates a sample control signal in response to at least a portion of the address (e.g., one or more high order bits of the address) of the one or more cells in the memory cell array. A data sampling circuit then samples the output signal of the sense amplifier in response to the sample control signal. The portion of the memory cell array address used to drive the control circuit may logically divide the memory cell array into two or more sections. The control circuit may adjust the timing of the sample control signal in accordance with the proximity of a memory cell array section to the sense amplifier.
    • 提供半导体器件及其数据采样方法,其中基于包含数据的存储单元阵列部分的相对位置从存储器单元阵列采样数据。 感测放大器响应于存储器单元阵列中的一个或多个单元的地址产生输出信号。 控制电路响应于存储器单元阵列中的一个或多个单元的地址的至少一部分(例如,地址的一个或多个高位)而产生采样控制信号。 然后,数据采样电路响应于采样控制信号对读出放大器的输出信号进行采样。 用于驱动控制电路的存储单元阵列地址的部分可逻辑地将存储单元阵列划分成两个或多个区段。 控制电路可以根据存储单元阵列部分与感测放大器的接近度来调整采样控制信号的定时。
    • 7. 发明授权
    • Integrated circuit memory devices having programmable output driver circuits therein
    • US06362656B1
    • 2002-03-26
    • US09753927
    • 2001-01-03
    • Sang-jae Rhee
    • Sang-jae Rhee
    • H03K190175
    • Output drivers preferably contain a plurality of driver circuits therein that are commonly connected to an output line to be driven and can be selectively enabled or disabled to increase or decrease drive capability, respectively. Driver circuits may include first and second control signal lines (e.g., MRS1, MRS2), a first pull-up/pull-down driver circuit having first and second data inputs, a first control input electrically coupled to the first control signal line (e.g., MRS1) and a second control input, and a second pull-up/pull-down driver circuit having first and second data inputs electrically coupled to the first and second data inputs of the first pull-up/pull-down driver circuit, respectively, a first control input electrically coupled to the second control signal line (e.g., MRS2) and a second control input. First and second complementary control signals lines (e.g., {overscore (MRS1+L )}, {overscore (MRS2+L )}) are also preferably provided and the second control inputs of the first pull-up/pull-down driver circuit and second pull-up/pull-down driver circuit are electrically coupled to the first and second complementary control signal lines, respectively. These control signal lines and complementary control signal lines can be used to control the number of driver circuits that are active within the output driver, based on loading conditions.
    • 8. 发明授权
    • Memory device having I/O sense amplifier with variable current gain
    • 具有可变电流增益的I / O读出放大器的存储器件
    • US06314029B1
    • 2001-11-06
    • US09543677
    • 2000-04-07
    • Tae-Young KoSang-jae Rhee
    • Tae-Young KoSang-jae Rhee
    • G11C708
    • G11C7/06G11C8/12
    • A semiconductor memory device having input/output sense amplifiers capable of varying gains using a column address and block selection signals. The input/output sense amplifiers can compensate for reduction of transfer rate according to distance between a selected memory block or sub memory block and the sense amplifiers. A semiconductor memory device of the present invention includes: a plurality of sub memory blocks divided by a column address in a memory block; a plurality of data input/output line pairs coupled to the sub memory blocks, for transmitting data in a selected sub memory block; and a plurality of input/output sense amplifiers for sensing and amplifying data from the data input/output line pairs, wherein each of the input/output sense amplifiers has a variable gain characteristic depending on distance between the selected sub memory block and the input/output sense amplifiers so as to minimize a difference in delay characteristic according to position of the selected sub memory block.
    • 具有能够使用列地址和块选择信号来改变增益的输入/输出读出放大器的半导体存储器件。 输入/输出读出放大器可根据所选存储块或子存储块与读出放大器之间的距离补偿传输速率的降低。 本发明的半导体存储器件包括:多个子存储器块,被存储块中的列地址划分; 耦合到子存储器块的多个数据输入/输出线对,用于在所选择的子存储器块中发送数据; 以及用于感测和放大来自数据输入/输出线对的数据的多个输入/输出读出放大器,其中每个输入/输出读出放大器具有取决于所选择的子存储块与输入/输出线对之间的距离的可变增益特性, 输出读出放大器,以便根据所选择的子存储块的位置最小化延迟特性的差异。
    • 9. 发明授权
    • Internal source voltage generator for a semiconductor memory device
    • 用于半导体存储器件的内部源电压发生器
    • US5946242A
    • 1999-08-31
    • US883537
    • 1997-06-26
    • Soo-In ChoSang-Jae Rhee
    • Soo-In ChoSang-Jae Rhee
    • G11C11/407G11C5/14G11C11/401G11C29/06G11C29/50G11C7/00
    • G11C5/147G11C29/50G11C11/401
    • A circuit for generating an internal source voltage signal responsive to an external source voltage signal in a semiconductor memory device prevents malfunction and extends the lifetime of the device by clamping the internal source signal if the device is in a normal operating mode when the external source signal is in a stress operating range. When the device is placed in a test mode, the circuit allows the internal source signal to increase in proportion to the level of the external source signal when the external source signal is in a stress operating range. The circuit includes in internal source voltage generator, which always clamps the internal source signal when the external source signal is in a normal operating range, and a pull-up unit which is activated in response to a control signal. The control signal is enabled when the device is placed in a test mode by combining external timing signals.
    • 用于在半导体存储器件中产生响应于外部源极电压信号的内部源极电压信号的电路防止故障,并且如果器件处于正常工作模式时通过钳位内部源极信号来延长器件的寿命,当外部源极信号 处于压力操作范围。 当器件处于测试模式时,当外部源极信号处于应力工作范围时,该电路允许内部源极信号与外部源极信号的电平成正比。 该电路包括内部源电压发生器,当外部源极信号处于正常工作范围时,它始终夹紧内部源极信号,以及响应控制信号激活的上拉单元。 当通过组合外部定时信号将器件置于测试模式时,控制信号被使能。