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1. 发明授权

US11049707B2 Apparatus and method for thermal assisted desorption ionization systems 有权
公开(公告)号：US11049707B2
公开(公告)日：2021-06-29
申请号：US16850443
申请日：2020-04-16
申请人： IONSENSE INC.
发明人： Jordan Krechmer , Brian D. Musselman
IPC分类号： H01J49/04 , G01N27/626 , H01J49/14 , G01N27/622 , G01N27/64 , H01J49/00 , H01J27/26 , H01J49/12 , H01J49/10 , H01J49/24
摘要： The present invention is directed to a method and device to desorb an analyte using heat to allow desorption of the analyte molecules, where the desorbed analyte molecules are ionized with ambient temperature ionizing species. In various embodiments of the invention a current is passed through a mesh upon which the analyte molecules are present. The current heats the mesh and results in desorption of the analyte molecules which then interact with gas phase metastable neutral molecules or atoms to form analyte ions characteristic of the analyte molecules.

2. 发明申请

US20200303175A1 APPARATUS AND METHOD FOR THERMAL ASSISTED DESORPTION IONIZATION SYSTEMS 审中-公开
公开(公告)号：US20200303175A1
公开(公告)日：2020-09-24
申请号：US16850443
申请日：2020-04-16
申请人： IONSENSE INC.
发明人： Jordan Krechmer , Brian D. Musselman
IPC分类号： H01J49/04 , H01J49/14 , G01N27/62 , G01N27/64 , H01J49/00 , H01J27/26 , H01J49/12 , H01J49/10 , H01J49/24
摘要： The present invention is directed to a method and device to desorb an analyte using heat to allow desorption of the analyte molecules, where the desorbed analyte molecules are ionized with ambient temperature ionizing species. In various embodiments of the invention a current is passed through a mesh upon which the analyte molecules are present. The current heats the mesh and results in desorption of the analyte molecules which then interact with gas phase metastable neutral molecules or atoms to form analyte ions characteristic of the analyte molecules.

3. 发明授权

US10283340B2 Apparatus and method for generating chemical signatures using differential desorption 有权
公开(公告)号：US10283340B2
公开(公告)日：2019-05-07
申请号：US16104479
申请日：2018-08-17
申请人： IONSENSE INC.
发明人： Brian D Musselman
IPC分类号： H01J49/00 , H01J49/16 , G01N1/40 , H01J49/04 , G01N30/00 , G01N30/06 , G01N1/02
摘要： The present invention is directed to a method and device to generate a chemical signature for a mixture of analytes. The present invention involves using a SPME surface to one or both absorb and adsorb the mixture of analytes. In an embodiment of the invention, the surface is then exposed to different temperature ionizing species chosen with appropriate spatial resolution to desorb a chemical signature for the mixture of analytes.

4. 发明申请

US20190006166A1 APPARATUS AND METHOD FOR GENERATING CHEMICAL SIGNATURES USING DIFFERENTIAL DESORPTION 审中-公开
公开(公告)号：US20190006166A1
公开(公告)日：2019-01-03
申请号：US16104479
申请日：2018-08-17
申请人： IONSENSE INC.
发明人： BRIAN D. MUSSELMAN
IPC分类号： H01J49/16 , H01J49/04 , H01J49/00 , G01N1/40 , G01N1/02 , G01N30/00 , G01N30/06
摘要： The present invention is directed to a method and device to generate a chemical signature for a mixture of analytes. The present invention involves using a SPME surface to one or both absorb and adsorb the mixture of analytes. In an embodiment of the invention, the surface is then exposed to different temperature ionizing species chosen with appropriate spatial resolution to desorb a chemical signature for the mixture of analytes.

5. 发明授权

US09514923B2 Apparatus and method for thermal assisted desorption ionization systems 有权
公开(公告)号：US09514923B2
公开(公告)日：2016-12-06
申请号：US14876677
申请日：2015-10-06
申请人： IONSENSE INC.
发明人： Jordan Krechmer , Brian D. Musselman
IPC分类号： H01J49/04 , H01J49/10 , G01N27/62 , H01J49/14 , G01N27/64 , H01J49/00 , H01J27/26 , H01J49/12 , H01J49/24
CPC分类号： H01J49/049 , G01N27/622 , G01N27/626 , G01N27/64 , H01J27/26 , H01J49/004 , H01J49/04 , H01J49/0431 , H01J49/10 , H01J49/126 , H01J49/14 , H01J49/24 , Y10T436/24
摘要： The present invention is directed to a method and device to desorb an analyte using heat to allow desorption of the analyte molecules, where the desorbed analyte molecules are ionized with ambient temperature ionizing species. In various embodiments of the invention a current is passed through a mesh upon which the analyte molecules are present. The current heats the mesh and results in desorption of the analyte molecules which then interact with gas phase metastable neutral molecules or atoms to form analyte ions characteristic of the analyte molecules.

6. 发明申请

US20160217993A1 APPARATUS AND METHOD FOR SAMPLING OF CONFINED SPACES 审中-公开
公开(公告)号：US20160217993A1
公开(公告)日：2016-07-28
申请号：US15081459
申请日：2016-03-25
申请人： IONSENSE INC.
发明人： BRIAN D. MUSSELMAN
IPC分类号： H01J49/10 , G01N27/62
CPC分类号： H01J49/10 , G01N1/2214 , G01N27/62 , H01J49/0027 , H01J49/0409
摘要： In various embodiments of the invention, a cargo container can be monitored at appropriate time intervals to determine that no controlled substances have been shipped with the cargo in the container. The monitoring utilizes reactive species produced from an atmospheric analyzer to ionize analyte molecules present in the container which are then analyzed by an appropriate spectroscopy system. In an embodiment of the invention, a sorbent surface can be used to absorb, adsorb or condense analyte molecules within the container whereafter the sorbent surface can be interrogated with the reactive species to generate analyte species characteristic of the contents of the container.

7. 发明授权

US09390899B2 Apparatus and method for sampling of confined spaces 有权
标题翻译：密闭空间取样装置及方法
公开(公告)号：US09390899B2
公开(公告)日：2016-07-12
申请号：US14493231
申请日：2014-09-22
申请人： IONSENSE, INC
发明人： Brian D Musselman
IPC分类号： G01N27/62 , H01J27/02 , H01J49/04 , H01J49/10 , H01J49/00 , G01N1/22
CPC分类号： H01J49/10 , G01N1/2214 , G01N27/62 , H01J49/0027 , H01J49/0409
摘要： In various embodiments of the invention, a cargo container can be monitored at appropriate time intervals to determine that no controlled substances have been shipped with the cargo in the container. The monitoring utilizes reactive species produced from an atmospheric analyzer to ionize analyte molecules present in the container which are then analyzed by an appropriate spectroscopy system. In an embodiment of the invention, a sorbent surface can be used to absorb, adsorb or condense analyte molecules within the container whereafter the sorbent surface can be interrogated with the reactive species to generate analyte species characteristic of the contents of the container.
摘要翻译：在本发明的各种实施例中，可以以适当的时间间隔来监视货物集装箱，以确定货物在集装箱中没有运送受控物质。监测利用从大气分析仪产生的反应物质电离存在于容器中的分析物分子，然后通过合适的光谱系统进行分析。在本发明的一个实施方案中，可以使用吸附剂表面来吸收，吸附或冷凝容器内的分析物分子，然后可以用反应性物质询问吸附剂表面以产生容器内容物特征的分析物质。

8. 发明申请

US20150364310A1 APPARATUS AND METHOD FOR GENERATING CHEMICAL SIGNATURES USING DIFFERENTIAL DESORPTION 有权
标题翻译：使用差异化解产生化学符号的装置和方法
公开(公告)号：US20150364310A1
公开(公告)日：2015-12-17
申请号：US14738899
申请日：2015-06-14
申请人： IONSENSE INC.
发明人： BRIAN D. MUSSELMAN
IPC分类号： H01J49/16 , H01J49/00
CPC分类号： H01J49/165 , G01N1/4022 , G01N2001/028 , G01N2030/009 , G01N2030/062 , H01J49/0031 , H01J49/045 , H01J49/16
摘要： The present invention is directed to a method and device to generate a chemical signature for a mixture of analytes. The present invention involves using a SPME surface to one or both absorb and adsorb the mixture of analytes. In an embodiment of the invention, the surface is then exposed to different temperature ionizing species chosen with appropriate spatial resolution to desorb a chemical signature for the mixture of analytes.
摘要翻译：本发明涉及一种生成分析物混合物的化学特征的方法和装置。本发明涉及使用SPME表面吸收和吸附分析物混合物中的一种或两种。在本发明的一个实施方案中，然后将表面暴露于用适当的空间分辨率选择的不同温度的离子化物质以解吸分析物混合物的化学特征。

9. 发明申请

US20150008315A1 APPARATUS AND METHOD FOR SAMPLING OF CONFINED SPACES 审中-公开
标题翻译：装置和采样限制空间的方法
公开(公告)号：US20150008315A1
公开(公告)日：2015-01-08
申请号：US14493231
申请日：2014-09-22
申请人： IONSENSE, INC
发明人： BRIAN D. MUSSELMAN
IPC分类号： H01J49/04 , G01N1/22 , H01J49/00
CPC分类号： H01J49/10 , G01N1/2214 , G01N27/62 , H01J49/0027 , H01J49/0409
摘要： In various embodiments of the invention, a cargo container can be monitored at appropriate time intervals to determine that no controlled substances have been shipped with the cargo in the container. The monitoring utilizes reactive species produced from an atmospheric analyzer to ionize analyte molecules present in the container which are then analyzed by an appropriate spectroscopy system. In an embodiment of the invention, a sorbent surface can be used to absorb, adsorb or condense analyte molecules within the container whereafter the sorbent surface can be interrogated with the reactive species to generate analyte species characteristic of the contents of the container.
摘要翻译：在本发明的各种实施例中，可以以适当的时间间隔来监视货物集装箱，以确定货物在集装箱中没有运送受控物质。监测利用从大气分析仪产生的反应物质电离存在于容器中的分析物分子，然后通过合适的光谱系统进行分析。在本发明的一个实施方案中，可以使用吸附剂表面来吸收，吸附或冷凝容器内的分析物分子，然后可以用反应性物质询问吸附剂表面以产生容器内容物特征的分析物质。

10. 发明授权

US08895916B2 Apparatus and method for sampling of confined spaces 有权
标题翻译：密闭空间取样装置及方法
公开(公告)号：US08895916B2
公开(公告)日：2014-11-25
申请号：US14279644
申请日：2014-05-16
申请人： Ionsense, Inc
发明人： Brian D Musselman
IPC分类号： G01N27/62 , H01J27/02
CPC分类号： H01J49/10 , G01N1/2214 , G01N27/62 , H01J49/0027 , H01J49/0409
摘要： In various embodiments of the invention, a cargo container can be monitored at appropriate time intervals to determine that no controlled substances have been shipped with the cargo in the container. The monitoring utilizes reactive species produced from an atmospheric analyzer to ionize analyte molecules present in the container which are then analyzed by an appropriate spectroscopy system. In an embodiment of the invention, a sorbent surface can be used to absorb, adsorb or condense analyte molecules within the container whereafter the sorbent surface can be interrogated with the reactive species to generate analyte species characteristic of the contents of the container.
摘要翻译：在本发明的各种实施例中，可以以适当的时间间隔来监视货物集装箱，以确定货物在集装箱中没有运送受控物质。监测利用从大气分析仪产生的反应物质电离存在于容器中的分析物分子，然后通过合适的光谱系统进行分析。在本发明的一个实施方案中，可以使用吸附剂表面来吸收，吸附或冷凝容器内的分析物分子，然后可以用反应性物质询问吸附剂表面以产生容器内容物特征的分析物质。

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