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    • 5. 发明授权
    • 5-Alkoxy-picolinic acid calcium salts and anti-hypertensive composition
containing 5-alkoxy-picolinic acid calcium salts and anti-hypertensive
composition thereof
    • 含有5-烷氧基 - 吡啶甲酸钙盐及其抗高血压组合物的5-烷氧基 - 吡啶甲酸钙盐和抗高血压组合物
    • US4189489A
    • 1980-02-19
    • US838180
    • 1977-09-30
    • Takemi KoedaTakashi TsuruokaUichi ShibataHiroyasu AsaokaMitsugu HachisuOsamu ItohYasuharu SekizawaShigeharu InouyeTaro Niida
    • Takemi KoedaTakashi TsuruokaUichi ShibataHiroyasu AsaokaMitsugu HachisuOsamu ItohYasuharu SekizawaShigeharu InouyeTaro Niida
    • A61K31/44A61P9/12C07D213/65C07D213/79A61K31/445C07D213/89
    • C07D213/79C07D213/65
    • 5-Alkoxy-picolinic acids and the salts and the esters thereof represented by the formula (I): ##STR1## wherein R represents an alkyl group having 1 to 6 carbon atoms and M represents a hydrogen atom; a calcium atom; a sodium atom; a potassium atom; an aluminum atom; an unsubstituted phenyl group; a phenyl group substituted with one or more of an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms or a halogen atom (such as a chlorine, bromine, iodine, etc., atom); a phthalidyl group; an alkoxyalkyl group wherein the alkyl moiety and the alkoxy moiety each has 1 to 4 carbon atoms; or an acyloxyalkyl group having the formula ##STR2## wherein R.sub.2 represents a hydrogen atom or a methyl group and R.sub.3 represents an alkyl group having 1 to 5 carbon atoms (such as a methyl, n-propyl, isobutyl, t-butyl, etc., group), an alkoxy group having 1 to 4 carbon atoms, a phenyl group, a phenyl group substituted with one or more of an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms or a halogen atom (such as a chlorine, bromine, iodine, etc., atom) or an aralkyl group wherein the alkyl moiety has 1 to 3 carbon atoms, which are useful as anti-hypertensive agents, a process for preparing 5-alkoxy-picolinic acids and the salts and the esters thereof, and anti-hypertensive compositions containing the 5-alkoxy-picolinic acids and the salts and the esters thereof.
    • 5-烷氧基 - 吡啶甲酸及其由式(I)表示的盐及其酯:其中R表示具有1至6个碳原子的烷基,M表示氢原子; 钙原子; 一个钠原子; 钾原子; 铝原子; 未取代的苯基; 被一个或多个具有1至4个碳原子的烷基,具有1至4个碳原子的烷氧基或卤素原子(例如氯,溴,碘等)原子取代的苯基; 苯酞基; 其中烷基部分和烷氧基部分各自具有1至4个碳原子的烷氧基烷基; 或具有式“IMAGE”的酰氧基烷基,其中R 2表示氢原子或甲基,R 3表示具有1至5个碳原子的烷基(例如甲基,正丙基,异丁基,叔丁基等) ,基团),具有1至4个碳原子的烷氧基,苯基,被一个或多个具有1至4个碳原子的烷基取代的苯基,具有1至4个碳原子的烷氧基或卤素原子 (例如氯,溴,碘等原子)或其中烷基部分具有1至3个碳原子的芳烷基,其可用作抗高血压剂,制备5-烷氧基 - 吡啶甲酸的方法和 其盐和酯,以及含有5-烷氧基 - 吡啶甲酸及其盐及其酯的抗高血压组合物。
    • 7. 发明授权
    • Screw mounting structure of an injection molding machine
    • 注塑机的螺钉安装结构
    • US08790103B2
    • 2014-07-29
    • US13549434
    • 2012-07-14
    • Hiroyasu Asaoka
    • Hiroyasu Asaoka
    • B29C45/77
    • B29C45/60B29C45/1775
    • In a screw mounting structure of an injection molding machine in which a screw is fixed to a screw driving portion which transmits a rotating force and forward and backward thrusts to the screw, a fixing bushing for restricting movement of the screw in a rotating direction is fixed to the screw driving portion. A guide groove is formed in the fixing bushing in a direction orthogonal to a rotary axis of the screw, and retainers slide along the guide groove and are engaged with an engaging groove in a base portion of the screw, thereby restricting axial movement of the screw.
    • 在注射成型机的螺钉安装结构中,螺钉固定在螺旋驱动部分上,该螺杆驱动部分将旋转力和向前和向后的推力传递到螺杆,用于限制螺杆沿旋转方向运动的固定衬套固定 到螺杆驱动部。 在固定衬套中沿着与螺杆的旋转轴线正交的方向形成引导槽,并且保持器沿着引导槽滑动并且与螺钉的基部中的接合槽接合,从而限制螺杆的轴向运动 。
    • 10. 发明授权
    • Injection molding machine
    • 注塑机
    • US07431583B2
    • 2008-10-07
    • US11491243
    • 2006-07-24
    • Satoshi TakatsugiWataru ShiraishiHiroyasu AsaokaToshio IshikuroHiroshi Imamura
    • Satoshi TakatsugiWataru ShiraishiHiroyasu AsaokaToshio IshikuroHiroshi Imamura
    • B29C45/18B29C45/47B29C45/76
    • B29C45/18B29C31/02B29C45/76B29C2045/1891B29C2945/76096B29C2945/76107B29C2945/76183
    • The invention provides an injection molding capable of adjusting a detection level with a simple structure and detecting a deposit level of the resin pellets near a plasticizing screw. A cooling jacket is mounted so that a resin supplying hole of the cooling jacket communicates with a resin supplying hole of a heating cylinder. A sensor head mounted on a sensor mounting plate is inserted into the resin supplying hole through a sensor insertion port provided on a hopper plate and a resin inlet and detects the deposit level of the resin pellets deposited in the resin supplying hole. Changing the extent of insertion of the sensor head enables the resin pellets deposit detection level to be changed, and further, enables the deposit level near the outer periphery of the screw to be detected. Setting the sensor detection direction perpendicular to the resin deposit direction enables dirtying of the sensor detection surface by the resin pellets to be reduced, thus enabling erroneous detection readings to be reduced.
    • 本发明提供能够以简单的结构调节检测水平并检测塑化螺杆附近的树脂颗粒的沉积物水平的注射成型。 安装冷却套,使冷却套的树脂供给孔与加热筒的树脂供给孔连通。 安装在传感器安装板上的传感器头通过设置在料斗板和树脂入口上的传感器插入口插入到树脂供给孔中,并检测沉积在树脂供给孔中的树脂颗粒的沉积层。 改变传感器头的插入程度使树脂颗粒的沉积物检测水平发生变化,并且能够检测螺杆外周附近的沉积物水平。 设置与树脂沉积方向垂直的传感器检测方向可以使树脂颗粒污染传感器检测表面,从而减少误差检测读数。