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1. 发明授权

US08419649B2 Vital sign monitor for measuring blood pressure using optical, electrical and pressure waveforms 有权
标题翻译：使用光学，电气和压力波形测量血压的生命体征监测器
公开(公告)号：US08419649B2
公开(公告)日：2013-04-16
申请号：US12138194
申请日：2008-06-12
申请人： Matthew J. Banet , Zhou Zhou , Marshal Singh Dhillon , Robert J. Kopotic , Andrew Stanley Terry , Henk Visser, II
发明人： Matthew J. Banet , Zhou Zhou , Marshal Singh Dhillon , Robert J. Kopotic , Andrew Stanley Terry , Henk Visser, II
IPC分类号： A61B5/02
CPC分类号： A61B5/02125 , A61B5/0022 , A61B5/02133 , A61B5/0225 , A61B5/02416 , A61B5/0295 , A61B5/0402 , A61B5/0452 , A61B5/1118 , A61B5/14551 , A61B5/6824 , A61B5/721 , A61B5/7239 , A61B5/742
摘要： A method and apparatus for continuous measurement of blood pressure, based on pulse transit time, which does not require any external calibration. This technique, referred to herein as the ‘composite technique’, is carried out with a body-won sensor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of disposable sensors, typically placed on the patient's right arm and chest, connect to the body sensor and measure a time-dependent electrical waveform, optical waveform, and pressure waveform. The disposable sensors typically include an armband that features an inflatable bladder coupled to a pressure sensor, at least 3 electrical sensors (e.g. electrodes), and an optical sensor (e.g., a light source and photodiode) attached to a wrist-worn band.
摘要翻译：基于脉冲传播时间连续测量血压的方法和装置，其不需要任何外部校准。这种在技术上被称为复合技术的技术是用身体获得的传感器进行的，该传感器测量血压和其他生命体征，并将它们无线传输到远程监视器。通常放置在患者右臂和胸部的一次性传感器网络连接到身体传感器，并测量与时间有关的电波形，光学波形和压力波形。一次性传感器通常包括臂罩，其具有连接到压力传感器，至少3个电传感器（例如电极）和连接到腕带的光学传感器（例如，光源和光电二极管）的可充气囊。

2. 发明授权

US08442607B2 Hand-held vital signs monitor 有权
标题翻译：手持式生命体征监护仪
公开(公告)号：US08442607B2
公开(公告)日：2013-05-14
申请号：US11470708
申请日：2006-09-07
申请人： Matthew John Banet , Michael James Thompson , Zhou Zhou , Henk Visser, II , Adam Michael Fleming , Marshal Singh Dhillon , Andrew Stanley Terry
发明人： Matthew John Banet , Michael James Thompson , Zhou Zhou , Henk Visser, II , Adam Michael Fleming , Marshal Singh Dhillon , Andrew Stanley Terry
IPC分类号： A61B5/1455 , A61B5/02
CPC分类号： A61B5/0404 , A61B5/0006 , A61B5/002 , A61B5/0022 , A61B5/0082 , A61B5/02007 , A61B5/0205 , A61B5/02055 , A61B5/021 , A61B5/02125 , A61B5/029 , A61B5/04012 , A61B5/04014 , A61B5/04028 , A61B5/04085 , A61B5/04087 , A61B5/044 , A61B5/08 , A61B5/1112 , A61B5/14551 , A61B5/14552 , A61B5/6823 , A61B5/6832 , A61B5/7435 , A61B5/7475 , A61B7/04 , A61B2562/063 , A61B2562/166 , G06F19/00
摘要： The invention features a vital sign monitor that includes: 1) a hardware control component featuring a microprocessor that operates an interactive, icon-driven GUI on an LCD; and, 2) a sensor component that connects to the control component through a shielded coaxial cable. The sensor features: 1) an optical component that generates a first signal; 2) a plurality electrical components (e.g. electrodes) that generate a second signal; and, 3) an acoustic component that generates a third signal. The microprocessor runs compiled computer code that operates: 1) the touch panel LCD; 2) a graphical user interface that includes multiple icons corresponding to different software operations; 3) a file-management system for storing and retrieving vital sign information; and 4) USB and short-range wireless systems for transferring data to and from the device to a PC.
摘要翻译：本发明具有生命体征监测器，其包括：1）具有微处理器的硬件控制部件，其操作LCD上的交互式图标驱动GUI; 和2）通过屏蔽同轴电缆连接到控制部件的传感器部件。该传感器具有：1）产生第一信号的光学部件; 2）产生第二信号的多个电气部件（例如电极）; 和3）产生第三信号的声学分量。微处理器运行编译的电脑代码，操作方法：1）触摸屏LCD; 2）包括对应于不同软件操作的多个图标的图形用户界面; 3）用于存储和检索生命体征信息的文件管理系统; 以及4）用于将数据传输到设备和从设备传送到PC的USB和短距离无线系统。

3. 发明授权

US07993275B2 Bilateral device, system and method for monitoring vital signs 有权
标题翻译：双边装置，系统和监测生命体征的方法
公开(公告)号：US07993275B2
公开(公告)日：2011-08-09
申请号：US11420281
申请日：2006-05-25
申请人： Matthew John Banet , Michael James Thompson , Zhou Zhou , Henk Visser, II
发明人： Matthew John Banet , Michael James Thompson , Zhou Zhou , Henk Visser, II
IPC分类号： A61B5/02
CPC分类号： A61B5/02427 , A61B5/02255 , A61B5/0285 , A61B5/6826 , A61B5/6838 , A61B5/7239
摘要： The invention features a monitoring device that measures a patient's vital signs (e.g. blood pressure). The device features a first sensor configured to attach to a first portion of the patient's body that includes: i) a first electrode configured to generate a first electrical signal from the first portion of the patient's body; ii) a first light-emitting component; and iii) a first photodetector configured to receive radiation from the first portion of the patient's body after the radiation is emitted by the first light-emitting component and in response generate a first optical waveform. The device also features a second sensor that includes essentially the same components. An amplifier system, in electrical contact with the first and second electrodes, receives first and second electrical signals from the two sensors to generate an electrical waveform. A processor, in electrical contact with the amplifier system, receives the electrical waveform, the first optical waveform, and the second optical waveform. The processor runs computer code that processes the input waveforms with an algorithm to determine at least one of the patient's vital signs.
摘要翻译：本发明的特征在于测量患者生命体征（例如血压）的监测装置。该装置具有构造成附接到患者身体的第一部分的第一传感器，该第一传感器包括：i）构造成从患者身体的第一部分产生第一电信号的第一电极; ii）第一发光部件; 以及iii）第一光电检测器，被配置为在由所述第一发光部件发射所述辐射之后接收来自所述患者身体的所述第一部分的辐射，并且响应于产生第一光学波形。该装置还具有包括基本相同部件的第二传感器。与第一和第二电极电接触的放大器系统接收来自两个传感器的第一和第二电信号以产生电波形。与放大器系统电接触的处理器接收电波形，第一光波形和第二光波形。处理器运行计算机代码，其使用算法处理输入波形以确定至少一个患者的生命体征。

4. 发明申请

US20100130875A1 BODY-WORN SYSTEM FOR MEASURING BLOOD PRESSURE 审中-公开
标题翻译：用于测量血压的身体系统
公开(公告)号：US20100130875A1
公开(公告)日：2010-05-27
申请号：US12487283
申请日：2009-06-18
申请人： Matthew J. BANET , Kenneth R. HUNT , Henk VISSER, II
发明人： Matthew J. BANET , Kenneth R. HUNT , Henk VISSER, II
IPC分类号： A61B5/021 , A61B5/02
摘要： A system for measuring a blood pressure value from a patient features a sensor configured to be worn on the patient's thumb. The sensor includes one or two light sources that emit optical radiation, and a photodetector that detects the optical radiation after it passes through a portion of a vessel (e.g. an artery or capillary) in the patient's thumb to generate a first time-dependent signal (e.g. a PPG waveform). In embodiments the sensor is made from a flexible material that wraps around a portion of the patient's thumb (e.g. the base) while leaving the thumb's tip uncovered. This configuration is less awkward than most finger-worn sensors, and allows the patient to comfortably go about their day-to-day activities (e.g. reading, eating) with little obstruction. The system also includes at least two electrodes that are configured to be worn on the patient's body and detect electrical signals that are processed by an electrical circuit to generate a second time-dependent signal (e.g. an ECG waveform).
摘要翻译：用于测量来自患者的血压值的系统具有构造成佩戴在患者拇指上的传感器。该传感器包括一个或两个发出光辐射的光源，以及光电检测器，其在通过患者拇指中的血管（例如动脉或毛细管）的一部分之后检测光辐射以产生第一时间依赖性信号例如PPG波形）。在实施例中，传感器由柔性材料制成，该柔性材料围绕患者拇指（例如基部）的一部分，同时使拇指的尖端未被覆盖。这种配置比大多数手指磨损的传感器不那么尴尬，并且允许患者舒适地进行他们的日常活动（例如阅读，吃饭），几乎没有障碍。该系统还包括至少两个电极，其配置为佩戴在患者身上并检测由电路处理以产生第二时间相关信号（例如ECG波形）的电信号。

5. 发明申请

US20090018422A1 VITAL SIGN MONITOR FOR CUFFLESSLY MEASURING BLOOD PRESSURE USING A PULSE TRANSIT TIME CORRECTED FOR VASCULAR INDEX 有权
标题翻译：使用纠正于血管指数的脉冲运输时间对血压进行无血压测量的VITAL SIGN MONITOR
公开(公告)号：US20090018422A1
公开(公告)日：2009-01-15
申请号：US12138199
申请日：2008-06-12
申请人： Matthew J. BANET , Zhou ZHOU , Marshal S. DHILLON , Robert J. KOPOTIC , Andrew S. Terry , Henk Visser, II
发明人： Matthew J. BANET , Zhou ZHOU , Marshal S. DHILLON , Robert J. KOPOTIC , Andrew S. Terry , Henk Visser, II
IPC分类号： A61B5/02
CPC分类号： A61B5/02125 , A61B5/02007 , A61B5/021 , A61B5/0285 , A61B5/0456 , A61B5/7239 , A61B5/7257 , A61B5/7475 , A61B2562/08
摘要： A method and apparatus for measuring a patient's blood pressure featuring the following steps: 1) measuring a time-dependent optical waveform with an optical sensor; 2) measuring a time-dependent electrical signal with an electrical sensor; 3) estimating the patient's arterial properties using the optical waveform; 4) determining a pulse transit time (PTT) from the time-dependent electrical signal and the time-dependent optical waveform; and 5) calculating a blood pressure value using a mathematical model that includes the PTT and the patient's arterial properties.
摘要翻译：一种用于测量患者血压的方法和装置，其特征在于以下步骤：1）使用光学传感器测量与时间有关的光学波形; 2）用电传感器测量与时间有关的电信号; 3）使用光学波形估计患者的动脉特性; 4）根据时间相关电信号和时间依赖光波形确定脉冲传播时间（PTT）; 以及5）使用包括PTT和患者动脉特性的数学模型来计算血压值。

6. 发明申请

US20090018409A1 DEVICE FOR DETERMINING RESPIRATORY RATE AND OTHER VITAL SIGNS 有权
标题翻译：用于确定呼吸率和其他身体信号的装置
公开(公告)号：US20090018409A1
公开(公告)日：2009-01-15
申请号：US12171886
申请日：2008-07-11
申请人： Matthew J. Banet , Zhou Zhou , Robert J. Kopotic , Marshal Singh Dhillon , Andrew S. Terry , Henk Visser, II
发明人： Matthew J. Banet , Zhou Zhou , Robert J. Kopotic , Marshal Singh Dhillon , Andrew S. Terry , Henk Visser, II
IPC分类号： A61B5/00
CPC分类号： A61B5/0816 , A61B5/002 , A61B5/0022 , A61B5/02055 , A61B5/022 , A61B5/0408 , A61B5/0823 , A61B5/1455 , A61B5/6826 , A61B5/6838 , A61B5/7225 , A61B5/7257 , A61B5/726 , A61B7/04 , A61B2560/0412 , A61B2560/0462 , A61B2560/0468 , G06F19/00 , G16H40/67
摘要： A body-worn sensor that measures respiratory rate and other vital signs using an acoustic sensor (e.g., a small-scale sensor). The body-worn sensor features a chest-worn patch sensor that combines both the acoustic sensor and an ECG electrode into a single adhesive patch. To measure blood pressure, the device additionally performs a ‘composite’ PTT-based measurement that features both pressure-dependent and pressure-free measurements. The acoustic sensor measures respiration rate by recording sounds related to the patient's inspiration and expiration. The acoustic sensor is typically placed near the patient's trachea, but can also be placed on the middle right and left side of the chest, and the middle right and left side of the back.
摘要翻译：使用声传感器（例如小型传感器）测量呼吸频率和其他生命体征的身体磨损传感器。身体磨损的传感器具有胸部贴片传感器，其将声学传感器和ECG电极组合成单个粘合剂贴片。为了测量血压，该装置还进行“复合”基于PTT的测量，其具有压力依赖性和无压力测量。声学传感器通过记录与患者的吸气和呼气相关的声音来测量呼吸率。声学传感器通常放置在病人的气管附近，但也可以放置在胸部的中间右侧和左侧以及背部的中间右侧和左侧。

7. 发明申请

US20080319327A1 BODY-WORN SENSOR FEATURING A LOW-POWER PROCESSOR AND MULTI-SENSOR ARRAY FOR MEASURING BLOOD PRESSURE 审中-公开
标题翻译：身体传感器专用低功率处理器和用于测量血压的多传感器阵列
公开(公告)号：US20080319327A1
公开(公告)日：2008-12-25
申请号：US12146432
申请日：2008-06-25
申请人： Matthew J. Banet , Zhou Zhou , Kenneth Robert Hunt , Henk Visser, II
发明人： Matthew J. Banet , Zhou Zhou , Kenneth Robert Hunt , Henk Visser, II
IPC分类号： A61B5/021
CPC分类号： A61B5/021 , A61B5/0059 , A61B5/02007 , A61B5/02125 , A61B5/0245 , A61B5/14551 , A61B5/6824 , A61B5/6826 , A61B5/6838 , A61B2560/0209 , A61B2562/164
摘要： A system is described that continuously measures a patient's blood pressure over a length of time. The system features a sensor assembly featuring a flexible cable configured to wrap around a portion of a patient's arm. The flexible cable features a back surface that includes at least two electrodes that are positioned to contact the patient's skin to generate electrical signals. It additionally features an optical sensor that includes at least one light source and at least one photodetector. These components form an optical sensor that is configured to generate an optical signal by detecting optical radiation emitted by the at least one light source and reflected from a blood vessel underneath the patient's skin.
摘要翻译：描述了在一段时间内持续测量患者的血压的系统。该系统具有传感器组件，该传感器组件具有柔性电缆，该柔性电缆构造成围绕患者手臂的一部分。柔性电缆具有后表面，其包括至少两个电极，其被定位成接触患者的皮肤以产生电信号。它还具有包括至少一个光源和至少一个光电检测器的光学传感器。这些组件形成光学传感器，其被配置为通过检测由至少一个光源发射并从患者皮肤下方的血管反射的光辐射来产生光学信号。

8. 发明申请

US20080312542A1 MULTI-SENSOR ARRAY FOR MEASURING BLOOD PRESSURE 审中-公开
标题翻译：用于测量血压的多传感器阵列
公开(公告)号：US20080312542A1
公开(公告)日：2008-12-18
申请号：US12139219
申请日：2008-06-13
申请人： Matthew J. BANET , Henk VISSER, II , Zhou ZHOU , Kenneth R. HUNT
发明人： Matthew J. BANET , Henk VISSER, II , Zhou ZHOU , Kenneth R. HUNT
IPC分类号： A61B5/021
CPC分类号： A61B5/021 , A61B5/02125 , A61B5/145
摘要： A sensor for monitoring a patient's blood pressure, the sensor including a housing unit with a back surface and which includes: a pair of electrodes mounted on the back surface; an optical system mounted on the back surface and including at least one light source that emits optical radiation near 570 nm and at least one photodetector; a first amplifier which generates an analog electrical waveform from the electrical signals from the electrodes; a second amplifier that generates an analog optical waveform from the optical signal from the photodetector; analog-to-digital converter circuitry configured to receive the analog electrical waveform and generate a digital electrical waveform therefrom and to receive the analog optical waveform and generate a digital optical waveform therefrom; and a processor programmed to receive the digital electrical and optical waveforms and determine a pulse transit time for the patient which is a measure of a separation in time of a first feature of the digital electrical waveform and a second feature of the digital optical waveform and to use the pulse transit time to determine a blood pressure value for the patient.
摘要翻译：一种用于监测患者血压的传感器，所述传感器包括具有后表面的壳体单元，其包括：安装在所述后表面上的一对电极; 安装在所述背面上并包括发射570nm附近的光辐射的至少一个光源和至少一个光电检测器的光学系统; 第一放大器，从电极的电信号产生模拟电波形; 第二放大器，从光电检测器的光信号产生模拟光波形; 模拟 - 数字转换器电路，被配置为接收模拟电波形并从其产生数字电波形，并接收模拟光波形并从其产生数字光波形; 以及处理器，其被编程为接收数字电波和光波形并确定患者的脉冲传播时间，该时间是数字电波形的第一特征和数字光波形的第一特征在时间上的分离的量度，以及数字光波形的第二特征，使用脉搏传播时间来确定患者的血压值。

9. 发明授权

US07803120B2 Bilateral device, system and method for monitoring vital signs 有权
标题翻译：双边装置，系统和监测生命体征的方法
公开(公告)号：US07803120B2
公开(公告)日：2010-09-28
申请号：US11420744
申请日：2006-05-27
申请人： Matthew John Banet , Michael James Thompson , Zhou Zhou , Henk Visser, II
发明人： Matthew John Banet , Michael James Thompson , Zhou Zhou , Henk Visser, II
IPC分类号： A61B5/02 , A61B5/04
CPC分类号： A61B5/02427 , A61B5/02255 , A61B5/0285 , A61B5/6826 , A61B5/6838 , A61B5/7239
摘要： The invention features a monitoring device that measures a patient's vital signs (e.g.). The device features a first sensor configured to attach to a first portion of the patient's body that includes: i)a first electrode configured to generate a first electrical signal fron the first portion of the patient's body; ii)a first light-emitting component; and iii)a first photodetector configured to receive radiation from the first portion of the patient's body after the radiation is emitted by the first light-emiting component and in response generate a first optical waveform. The device also features a second sensor that includes essentially the same components. An amplifier system, in electrical contact with the first and second electrodes, receives first and second electrical signal from the two sensors to generate an electrical waveform. A processor, in electrical contact with the amplifier system, receives the electrical waveform, the first optical waveform, and the second optical waveform. The processor runs computer code that processes the input waveforms with an algorithm to determine at least one of the patient's vital signs.
摘要翻译：本发明的特征在于测量患者的生命体征（例如）的监测装置。该装置具有构造成附接到患者身体的第一部分的第一传感器，其包括：i）被配置为在患者身体的第一部分产生第一电信号的第一电极; ii）第一发光部件; 以及iii）第一光电检测器，被配置为在所述第一发光部件发射所述辐射之后接收来自所述患者身体的所述第一部分的辐射，并且响应于产生第一光学波形。该装置还具有包括基本相同部件的第二传感器。与第一和第二电极电接触的放大器系统接收来自两个传感器的第一和第二电信号以产生电波形。与放大器系统电接触的处理器接收电波形，第一光波形和第二光波形。处理器运行计算机代码，其使用算法处理输入波形以确定至少一个患者的生命体征。

10. 发明申请

US20120108983A1 BODY-WORN SENSOR FEATURING A LOW-POWER PROCESSOR AND MULTI-SENSOR ARRAY FOR MEASURING BLOOD PRESSURE 审中-公开
标题翻译：身体传感器专用低功率处理器和用于测量血压的多传感器阵列
公开(公告)号：US20120108983A1
公开(公告)日：2012-05-03
申请号：US13346408
申请日：2012-01-09
申请人： Matthew J. Banet , Zhou Zhou , Kenneth Robert Hunt , Henk Visser, II
发明人： Matthew J. Banet , Zhou Zhou , Kenneth Robert Hunt , Henk Visser, II
IPC分类号： A61B6/00 , A61B5/022
CPC分类号： A61B5/021 , A61B5/0059 , A61B5/02007 , A61B5/02125 , A61B5/0245 , A61B5/14551 , A61B5/6824 , A61B5/6826 , A61B5/6838 , A61B2560/0209 , A61B2562/164
摘要： A system is described that continuously measures a patient's blood pressure over a length of time. The system features a sensor assembly featuring a flexible cable configured to wrap around a portion of a patient's arm. The flexible cable features a back surface that includes at least two electrodes that are positioned to contact the patient's skin to generate electrical signals. It additionally features an optical sensor that includes at least one light source and at least one photodetector. These components form an optical sensor that is configured to generate an optical signal by detecting optical radiation emitted by the at least one light source and reflected from a blood vessel underneath the patient's skin.
摘要翻译：描述了在一段时间内持续测量患者的血压的系统。该系统具有传感器组件，该传感器组件具有柔性电缆，该柔性电缆构造成围绕患者手臂的一部分。柔性电缆具有后表面，其包括至少两个电极，其被定位成接触患者的皮肤以产生电信号。它还具有包括至少一个光源和至少一个光电检测器的光学传感器。这些组件形成光学传感器，其被配置为通过检测由至少一个光源发射并从患者皮肤下方的血管反射的光辐射来产生光学信号。

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