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1. 发明授权

US08977029B2 Method and system for multi-atlas segmentation of brain computed tomography image data 有权
标题翻译：大脑计算机断层扫描图像数据的多图谱分割方法与系统
公开(公告)号：US08977029B2
公开(公告)日：2015-03-10
申请号：US13974481
申请日：2013-08-23
申请人： Kaifang Du , Li Zhang , Tony Nguyen , Vincent Ordy , Heinz Fichte , Hendrik Ditt
发明人： Kaifang Du , Li Zhang , Tony Nguyen , Vincent Ordy , Heinz Fichte , Hendrik Ditt
IPC分类号： G06K9/00 , G06T7/00
CPC分类号： G06T7/0079 , G06T7/11 , G06T7/174 , G06T2200/04 , G06T2207/10081 , G06T2207/20128 , G06T2207/20224 , G06T2207/30016 , G06T2207/30101
摘要： A method and system for multi-atlas segmentation brain structures and vessel territories in a brain computed tomography (CT) image is disclosed. Each of a plurality of atlas images is individually registered to an input brain CT image, resulting in a plurality of warped atlas images. A region of interest is defined based on labeled brain structures in each of the plurality of warped atlas images. For each atlas image, a respective sum of squared difference (SSD) value is calculated between the corresponding warped atlas image and the brain CT image within the region of interest defined for the corresponding warped atlas image. A number of the atlas images are selected based on the SSD values calculated for the atlas images. The brain structures and vessel territories are segmented in the brain CT image using only the selected atlas images.
摘要翻译：公开了一种脑图像计算机断层扫描（CT）图像中多图集分割脑结构和血管领域的方法和系统。多个图集图像中的每一个被单独登记到输入脑CT图像，导致多个翘曲的图集图像。基于多个翘曲图谱中的每一个中的标记脑结构来定义感兴趣区域。对于每个图集图像，在对应的扭曲图谱图像和对于相应的扭曲图谱图像限定的关注区域内的脑CT图像之间计算出相应的平方差（SSD）值的和。基于为图集图像计算的SSD值来选择多个图集图像。大脑结构和血管领域在脑CT图像中仅使用所选择的图谱进行分割。

2. 发明申请

US20140056501A1 Method and System for Multi-Atlas Segmentation of Brain Computed Tomography Image Data 有权
标题翻译：大脑计算机断层扫描图像数据的多图集分割方法与系统
公开(公告)号：US20140056501A1
公开(公告)日：2014-02-27
申请号：US13974481
申请日：2013-08-23
申请人： Kaifang Du , Li Zhang , Tony Nguyen , Vincent Ordy , Heinz Fichte , Hendrik Ditt
发明人： Kaifang Du , Li Zhang , Tony Nguyen , Vincent Ordy , Heinz Fichte , Hendrik Ditt
IPC分类号： G06T7/00
CPC分类号： G06T7/0079 , G06T7/11 , G06T7/174 , G06T2200/04 , G06T2207/10081 , G06T2207/20128 , G06T2207/20224 , G06T2207/30016 , G06T2207/30101
摘要： A method and system for multi-atlas segmentation brain structures and vessel territories in a brain computed tomography (CT) image is disclosed. Each of a plurality of atlas images is individually registered to an input brain CT image, resulting in a plurality of warped atlas images. A region of interest is defined based on labeled brain structures in each of the plurality of warped atlas images. For each atlas image, a respective sum of squared difference (SSD) value is calculated between the corresponding warped atlas image and the brain CT image within the region of interest defined for the corresponding warped atlas image. A number of the atlas images are selected based on the SSD values calculated for the atlas images. The brain structures and vessel territories are segmented in the brain CT image using only the selected atlas images.
摘要翻译：公开了一种脑图像计算机断层扫描（CT）图像中多图集分割脑结构和血管领域的方法和系统。多个图集图像中的每一个被单独登记到输入脑CT图像，导致多个翘曲的图集图像。基于多个翘曲图谱中的每一个中的标记脑结构来定义感兴趣区域。对于每个图集图像，在对应的扭曲图谱图像和对于相应的扭曲图谱图像限定的关注区域内的脑CT图像之间计算出相应的平方差（SSD）值的和。基于为图集图像计算的SSD值来选择多个图集图像。大脑结构和血管领域在脑CT图像中仅使用所选择的图谱进行分割。

3. 发明申请

US20100158337A1 METHOD AND DEVICE FOR PERFORMING A COMPARISON BETWEEN A LEFT AND A RIGHT HALF OF THE BRAIN OF A PATIENT 审中-公开
标题翻译：用于在患者的大脑左侧和右半角之间进行比较的方法和装置
公开(公告)号：US20100158337A1
公开(公告)日：2010-06-24
申请号：US12639089
申请日：2009-12-16
申请人： Corinna Bürger , Heinz Fichte , Grzegorz Soza
发明人： Corinna Bürger , Heinz Fichte , Grzegorz Soza
IPC分类号： G06K9/00
CPC分类号： G06T7/0014 , A61B6/507 , G06T2207/10081 , G06T2207/10088 , G06T2207/30016 , G06T2207/30101
摘要： In order to compare a left and a right half of the brain of a patient on the basis of medical 2D or 3D image data records for determining the perfusion, the brain of the patient is subdivided into brain regions, wherein the number of brain regions is an even number n, a number n/2 of the brain regions being arranged in the right half of the brain and a number n/2 of the brain regions being arranged in the left half of the brain, with each of the brain regions arranged in the right half of the brain being unambiguously assigned to a brain region arranged in the left half of the brain, and the brain being subdivided by planes standing perpendicularly on a median sagittal plane. In at least one embodiment, the image data records are segmented, wherein brain image data records are generated which only include those picture elements of the image data records which represent the brain of the patient. In at least one embodiment, n partial image data records are determined in each of the brain image data records, wherein an m-th partial image data record only include those picture elements of the respective brain image data record, which represent an m-th of the n brain regions, with m=1 . . . n. In at least one embodiment, one or more characteristic values are calculated per m-th brain region by evaluating all m-th partial image data records according to a prescribed evaluation method. Finally, in at least one embodiment, the characteristic values of brain regions unambiguously assigned to one another are evaluated according to predetermined criteria for comparing the right and left half of the brain.
摘要翻译：为了基于用于确定灌注的医学2D或3D图像数据记录来比较患者的脑的左半部分和右半部分，将患者的脑细分为脑区域，其中脑区域的数量为偶数n，大脑区域的数量n / 2被布置在脑的右半部，并且脑区域的数目n / 2被布置在脑的左半部分中，每个脑区域排列在大脑的右半边被明确地分配到安排在脑的左半部分的脑区域，并且大脑被垂直放置在中间矢状面上的平面细分。在至少一个实施例中，分割图像数据记录，其中生成脑图像数据记录，其仅包括代表患者脑部的图像数据记录的那些图像元素。在至少一个实施例中，在每个脑图像数据记录中确定n个部分图像数据记录，其中第m个部分图像数据记录仅包括各个脑图像数据记录的那些图像元素，其表示第m 的n个脑区域，m = 1。。。 n。在至少一个实施例中，通过根据规定的评估方法评估所有第m个部分图像数据记录，每m个脑区域计算一个或多个特征值。最后，在至少一个实施例中，根据用于比较脑的右半部分和左半部分的预定标准来评估明确地分配给彼此的脑区域的特征值。

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