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1. 发明授权

US08702019B2 Transportation device 有权
标题翻译：运输装置
公开(公告)号：US08702019B2
公开(公告)日：2014-04-22
申请号：US12835460
申请日：2010-07-13
申请人： Chien-Lung Chen , Cheng-Hsien Chen , Chang-Jer Wu , Han-Ning Huang
发明人： Chien-Lung Chen , Cheng-Hsien Chen , Chang-Jer Wu , Han-Ning Huang
IPC分类号： A62C5/00 , B05B7/02 , B05B9/01 , F23D14/68
CPC分类号： C12N15/895 , A61M5/30 , A61M11/005 , A61M11/02 , A61M11/06 , A61M2037/0007 , B05B7/0012 , B05B7/0416 , B05B7/0433 , B05B17/0615
摘要： A transportation device, physically transporting material to a target, includes an input module, a transporting module and an output module. The input module provides a carrier fluid. The transporting module is coupled to the input module for receiving the carrier fluid in order to disperse/atomize the material. The material enters the input module through a first opening and reaches the target Through a second opening. The input module further includes a guiding unit having a length longer than or equal to the distance between the throat portion and the second opening. One end of the guiding unit connects the transporting module. The other end of the guiding unit has a guiding comer for connecting to the first opening.
摘要翻译：将材料物理运输到目标的运输装置包括输入模块，输送模块和输出模块。输入模块提供载体流体。传送模块耦合到输入模块以接收载体流体，以便分散/雾化材料。材料通过第一个开口进入输入模块，并通过第二个开口到达目标。所述输入模块还包括具有长于或等于所述喉部和所述第二开口之间的距离的长度的引导单元。引导单元的一端连接传送模块。引导单元的另一端具有用于连接到第一开口的引导角。

2. 发明申请

US20110011958A1 TRANSPORTATION DEVICE 有权
标题翻译：运输设备
公开(公告)号：US20110011958A1
公开(公告)日：2011-01-20
申请号：US12835460
申请日：2010-07-13
申请人： Chien-Lung Chen , Cheng-Hsien Chen , Chang-Jer Wu , Han-Ning Huang
发明人： Chien-Lung Chen , Cheng-Hsien Chen , Chang-Jer Wu , Han-Ning Huang
IPC分类号： B05B7/00
CPC分类号： C12N15/895 , A61M5/30 , A61M11/005 , A61M11/02 , A61M11/06 , A61M2037/0007 , B05B7/0012 , B05B7/0416 , B05B7/0433 , B05B17/0615
摘要： A transportation device, physically transporting a material to a target, includes an input module, a transporting module and an output module. The input module provides a carrier fluid. The transporting module is coupled to the input module for receiving the carrier fluid in order to disperse/atomize the material. The output module has a throat portion, a first opening and a second opening. The throat portion is positioned between the first opening and the second opening, and the aperture of the first opening is larger than that of the second opening. The distance between the throat portion and the second opening is equal to or smaller than the distance between the throat portion and the first opening and is between three and ten times of the throat portion aperture (d). The second opening has an expending angle which is between half and three times of the throat portion aperture angle) (½d°-3d°. The material enters the input module through the first opening and reaches the target through the second opening. The input module further includes a guiding unit having a length longer than or equal to the distance between the throat portion and the second opening. One end of the guiding unit connects the transporting module, and the size of the end connected to the transporting module is three times larger than the size of the throat portion. The other end of the guiding unit has a guiding corner for connecting to the first opening, and the angle of the guiding corner is between three and fifteen times of the throat portion angle (3d°-15d°).
摘要翻译：将材料物理运送到目标的运输装置包括输入模块，输送模块和输出模块。输入模块提供载体流体。传送模块耦合到输入模块以接收载体流体，以便分散/雾化材料。输出模块具有喉部，第一开口和第二开口。喉部位于第一开口和第二开口之间，并且第一开口的孔大于第二开口的开口。喉部和第二开口之间的距离等于或小于喉部和第一开口之间的距离，并且在喉部部分孔（d）的三到十倍之间。第二个开口的膨胀角是喉部孔径角的一半和三倍之间）（1/2d°-3d°），材料通过第一个开口进入输入模块，通过第二个开口到达目标，输入模块进一步包括具有长于或等于所述喉部和所述第二开口之间的距离的引导单元，所述引导单元的一端连接所述输送模块，并且连接到所述输送模块的端部的尺寸为三倍引导单元的另一端具有用于连接到第一开口的引导角，并且引导角的角度在喉部角度（3d°-15d°）的三到十五倍之间）。

3. 发明申请

US20100086613A1 CHITOSAN VEHICLE AND METHOD FOR MAKING SAME 审中-公开
标题翻译： CHITOSAN车辆及其制造方法
公开(公告)号：US20100086613A1
公开(公告)日：2010-04-08
申请号：US12245602
申请日：2008-10-03
申请人： Chang-Jer WU , Han-Ning Huang , Chien-Lung Chen , Cheng-Hsien Chen
发明人： Chang-Jer WU , Han-Ning Huang , Chien-Lung Chen , Cheng-Hsien Chen
IPC分类号： A61K9/14
CPC分类号： A61K47/61
摘要： The invention relates to chitosan (CS) vehicles with chitosan nanoparticles, as well as methods for making such chitosan vehicles and for using them to carry a DNA or proteins by forming CS-DNA or CS-protein complexes. The present invention also relates to CS-DNA or CS-protein complexes being useful for transdermal delivery of DNA or protein with a low-pressure gene gun. In another aspect, the present invention also relates to CS-DNA or CS-protein complexes being useful for transcutaneous delivery of a DNA or protein with a skin patch. Further aspects of the present invention relate to methods for making CS-DNA or CS-protein complexes and for using them for diagnostic, therapeutic and biological industrial applications.
摘要翻译：本发明涉及具有壳聚糖纳米颗粒的壳聚糖（CS）载体，以及制备这种壳聚糖载体的方法，并且通过形成CS-DNA或CS-蛋白复合物来使用它们携带DNA或蛋白质。本发明还涉及用于用低压基因枪透皮递送DNA或蛋白质的CS-DNA或CS-蛋白复合物。另一方面，本发明还涉及可用于皮肤贴剂经皮递送DNA或蛋白质的CS-DNA或CS-蛋白复合物。本发明的其它方面涉及制备CS-DNA或CS-蛋白复合物并将其用于诊断，治疗和生物工业应用的方法。

4. 发明申请

US20110182976A1 LIPOPLEX-PATCH BASED DNA VACCINE 审中-公开
标题翻译：基于LIPOPLEX-PATCH的DNA疫苗
公开(公告)号：US20110182976A1
公开(公告)日：2011-07-28
申请号：US12695880
申请日：2010-01-28
申请人： Chang-Jer Wu , Jing-Yan Cheng , Han-Ning Huang
发明人： Chang-Jer Wu , Jing-Yan Cheng , Han-Ning Huang
IPC分类号： A61K9/127 , A61K39/12 , A61P31/12
CPC分类号： A61K9/127 , A61K9/703 , A61K39/12 , A61K2039/53 , A61K2039/54 , A61K2039/55555 , A61K2039/57 , C12N2770/24134 , Y02A50/39
摘要： This invention relates to a DNA vaccine preparation in a patch against virus infection comprising a DNA construct incorporated in a liposome, wherein the ratio of DNA to liposome is from 1:1 to 1:10; wherein the DNA vaccine preparation is preferably administrated after a pretreatment with alpha hydroxyl acids.
摘要翻译：本发明涉及一种针对病毒感染的贴剂中的DNA疫苗制剂，其包含掺入脂质体中的DNA构建体，其中DNA与脂质体的比例为1:1至1:10; 其中所述DNA疫苗制剂优选在用α羟基酸进行预处理后施用。

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