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1. 发明授权

US06660829B1 Collagen-based dispersions and macroporous structures 失效
标题翻译：基于胶原的分散体和大孔结构
公开(公告)号：US06660829B1
公开(公告)日：2003-12-09
申请号：US09822282
申请日：2001-03-30
申请人： Gennaro J. Maffia
发明人： Gennaro J. Maffia
IPC分类号： A61K3812
CPC分类号： C08L89/06 , C08H1/06
摘要： The present invention pertains to the production of collagen-based products in the form of dispersions and macroporous structures using untreated raw fibrillar type I corium as the starting material. The resulting dispersions have improved characteristics making them ideal for use in environmental applications as a settling aid, a filtration aid, a fractionation medium, an oil droplet stabilizer, a water purification aid, and a water siphoning aid. The dispersions may be further treated in accordance with the methods described herein to form macroporous structures suitable for biotechnological applications including use as a cell culturing substrate and non-biotechnological applications including use as an organic aerogel.
摘要翻译：本发明涉及使用未处理的原纤维型I型铈作为起始原料的分散体和大孔结构形式的胶原基产品的生产。所得分散体具有改进的特性，使其成为用作环境应用中的沉降助剂，助滤剂，分馏介质，油滴稳定剂，水净化助剂和吸水助剂的理想选择。分散体可以根据本文所述的方法进一步处理以形成适于生物技术应用的大孔结构，包括用作细胞培养基质和非生物技术应用，包括用作有机气凝胶。

2. 发明授权

US4533780A Natural gas conversion 失效
标题翻译：天然气转换
公开(公告)号：US4533780A
公开(公告)日：1985-08-06
申请号：US601139
申请日：1984-04-16
申请人： Gennaro J. Maffia
发明人： Gennaro J. Maffia
IPC分类号： C10G5/00 , C07C1/00 , C07C2/00 , C07C2/08 , C07C9/00 , C07C9/04 , C07C11/02 , C07C67/00
CPC分类号： C07C11/02
摘要： A method of synthesizing hydrocarbons from a methane source which includes the steps of separating a mixture of lower alkanes to form a first fraction containing predominately methane and at least one second fraction containing predominately C.sub.2 + alkanes; dehydrogenating the second C.sub.2 + fraction to form an effluent comprising C.sub.2 + olefins; contacting the methane fraction with an oxide of a metal which oxide when contacted with methane at between about 500.degree. and 1000.degree. C. is reduced and produces higher hydrocarbon products and water; and oligomerizing the C.sub.2 + olefin fraction and the methane contacting effluent to produce higher hydrocarbon products.
摘要翻译：一种从甲烷源合成烃的方法，其包括分离低级烷烃的混合物以形成主要含甲烷的第一级分和至少一种主要含有C2 +烷烃的第二馏分的步骤; 使第二C2 +级分脱氢以形成包含C2 +烯烃的流出物; 使甲烷部分与金属氧化物接触，金属氧化物在与甲烷接触时在约500至1000℃之间被还原并产生较高的烃产物和水; 并使C2 +烯烃部分和甲烷接触流出物低聚以产生更高级的烃产物。

3. 发明申请

US20100221136A1 Porous Metallic Structures 有权
标题翻译：多孔金属结构
公开(公告)号：US20100221136A1
公开(公告)日：2010-09-02
申请号：US12696294
申请日：2010-01-29
申请人： Gennaro J. Maffia
发明人： Gennaro J. Maffia
IPC分类号： B22F3/11 , B32B15/02
CPC分类号： B22F3/1121 , B22F3/11 , B22F3/12 , B22F2998/00 , Y10T428/12014 , Y10T428/12479 , Y10T428/24997 , B22F7/004
摘要： In one aspect, there are provided methods for producing porous metallic structures, wherein the methods involve the use of collagen fibrils on the nanometer scale as a “sacrificial” scaffold upon which metal particles are deposited. Also disclosed are structures comprising a porous metallic matrix having favorable strength, porosity, and density characteristics. Structures produced in accordance with the present disclosure are useful for, inter alia, the fabrication of devices such as filters, heat exchangers, sound absorbers, electrochemical cathodes, fuel cells, catalyst supports, fluid treatment units, lightweight structures and biomaterials.
摘要翻译：一方面，提供了用于生产多孔金属结构的方法，其中所述方法涉及在纳米级上使用胶原纤维作为沉积金属颗粒的“牺牲”支架。还公开了包括具有良好强度，孔隙率和密度特性的多孔金属基体的结构。根据本公开生产的结构尤其可用于制造诸如过滤器，热交换器，吸声器，电化学阴极，燃料电池，催化剂载体，流体处理单元，轻质结构和生物材料的装置。

4. 发明申请

US20130171466A1 POROUS METALLIC STRUCTURES 审中-公开
标题翻译：多孔金属结构
公开(公告)号：US20130171466A1
公开(公告)日：2013-07-04
申请号：US13709817
申请日：2012-12-10
申请人： GENNARO J. MAFFIA
发明人： GENNARO J. MAFFIA
IPC分类号： B22F3/11
CPC分类号： B22F3/1121 , B22F3/11 , B22F3/12 , B22F2998/00 , Y10T428/12014 , Y10T428/12479 , Y10T428/24997 , B22F7/004
摘要： In one aspect, there are provided methods for producing porous metallic structures, wherein the methods involve the use of collagen fibrils on the nanometer scale as a “sacrificial” scaffold upon which metal particles are deposited. Also disclosed are structures comprising a porous metallic matrix having favorable strength, porosity, and density characteristics. Structures produced in accordance with the present disclosure are useful for, inter alia, the fabrication of devices such as filters, heat exchangers, sound absorbers, electrochemical cathodes, fuel cells, catalyst supports, fluid treatment units, lightweight structures and biomaterials.
摘要翻译：一方面，提供了用于生产多孔金属结构的方法，其中所述方法涉及在纳米级上使用胶原纤维作为沉积金属颗粒的“牺牲”支架。还公开了包括具有良好强度，孔隙率和密度特性的多孔金属基体的结构。根据本公开生产的结构尤其可用于制造诸如过滤器，热交换器，吸声器，电化学阴极，燃料电池，催化剂载体，流体处理单元，轻质结构和生物材料的装置。

5. 发明授权

US08329091B2 Porous metallic structures 有权
标题翻译：多孔金属结构
公开(公告)号：US08329091B2
公开(公告)日：2012-12-11
申请号：US12696294
申请日：2010-01-29
申请人： Gennaro J. Maffia
发明人： Gennaro J. Maffia
IPC分类号： B22F3/11 , B32B15/02
CPC分类号： B22F3/1121 , B22F3/11 , B22F3/12 , B22F2998/00 , Y10T428/12014 , Y10T428/12479 , Y10T428/24997 , B22F7/004
摘要： In one aspect, there are provided methods for producing porous metallic structures, wherein the methods involve the use of collagen fibrils on the nanometer scale as a “sacrificial” scaffold upon which metal particles are deposited. Also disclosed are structures comprising a porous metallic matrix having favorable strength, porosity, and density characteristics. Structures produced in accordance with the present disclosure are useful for, inter alia, the fabrication of devices such as filters, heat exchangers, sound absorbers, electrochemical cathodes, fuel cells, catalyst supports, fluid treatment units, lightweight structures and biomaterials.
摘要翻译：一方面，提供了用于生产多孔金属结构的方法，其中所述方法涉及使用纳米级的胶原纤维作为沉积金属颗粒的牺牲支架。还公开了包括具有良好强度，孔隙率和密度特性的多孔金属基体的结构。根据本公开生产的结构尤其可用于制造诸如过滤器，热交换器，吸声器，电化学阴极，燃料电池，催化剂载体，流体处理单元，轻质结构和生物材料的装置。

6. 发明授权

US5162593A Tertiary butyl alcohol preparation 失效
标题翻译：叔丁醇制备
公开(公告)号：US5162593A
公开(公告)日：1992-11-10
申请号：US797649
申请日：1991-11-25
申请人： Gennaro J. Maffia , John C. Jubin
发明人： Gennaro J. Maffia , John C. Jubin
IPC分类号： C07C29/50 , C07C409/04
CPC分类号： C07C409/04 , C07C29/50 , C07C407/00 , C07C407/003
摘要： TBA is prepared by a process wherein isobutane is continuously oxidized to a TBA/TBHP mixture, TBA is recovered from the mixture and TBHP is recycled to the isobutane oxidation step wherein it is converted to TBA at the isobutane oxidation conditions.
摘要翻译： TBA通过其中异丁烷被连续氧化成TBA / TBHP混合物的方法制备，从混合物中回收TBA，并将TBHP再循环至异丁烷氧化步骤，其中其在异丁烷氧化条件下转化为TBA。

7. 发明授权

US4863856A Weighted collagen microsponge for immobilizing bioactive materials 失效
标题翻译：用于固定生物活性物质的加重胶原微球
公开(公告)号：US4863856A
公开(公告)日：1989-09-05
申请号：US932088
申请日：1986-11-18
申请人： Robert C. Dean, Jr. , Frederick H. Silver , Richard A. Berg , Philip G. Phillips , Peter W. Runstadler, Jr. , Gennaro J. Maffia
发明人： Robert C. Dean, Jr. , Frederick H. Silver , Richard A. Berg , Philip G. Phillips , Peter W. Runstadler, Jr. , Gennaro J. Maffia
IPC分类号： C12N1/00 , C12N5/00 , C12N11/02 , C12P1/00
CPC分类号： C12N1/00 , C12N11/02 , C12N5/0075 , C12P1/00 , C12N2533/54
摘要： Weighted collagen microsponges having a highly crosslinked collagen matrix are described suitable for use in culturing organisms in motive reactor systems. The microsponges have an open to the surface pore structure, and pore sizes and volumes suitable for immobilizing a variety of bioactive materials. The microsponges also have an average particle size in the range of about 100 to about 1000 microns and a specific gravity above about 1.05.
摘要翻译：描述了具有高度交联的胶原基质的加重胶原微球适用于在动力反应器系统中培养生物体。微球具有开放的表面孔结构，并且适合于固定各种生物活性材料的孔径和体积。微球也具有约100至约1000微米范围内的平均粒度和约1.05以上的比重。

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