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1. 发明授权

US4796634A Methods and apparatus for monitoring cardiac output 失效
标题翻译：监测心输出量的方法和装置
公开(公告)号：US4796634A
公开(公告)日：1989-01-10
申请号：US763992
申请日：1985-08-09
申请人： Lee L. Huntsman , Richard S. Leard , Gary L. Tarbox , Stephen R. Barnes , Barry D. McLaren
发明人： Lee L. Huntsman , Richard S. Leard , Gary L. Tarbox , Stephen R. Barnes , Barry D. McLaren
IPC分类号： A61B5/029 , A61B8/06 , G01P5/24 , A61B10/00
CPC分类号： A61B8/467 , A61B5/029 , A61B8/065 , G01P5/242
摘要： A method and apparatus for ascertaining the cardiac output of a human patient, said method comprising the steps of: measuring the systolic velocity of the blood flowing through the patient's descending aorta; determining the cross-sectional area of the patient's ascending aorta; and calculating the patient's cardiac output from said systolic velocity and said aortic area. The cardiac output can be converted: (1) to cardiac index by dividing it by the patient's body surface area, and (2) to systemic vascular resistance by dividing a value representing the patient's blood pressure by said cardiac output.
摘要翻译：一种用于确定人类患者的心输出量的方法和装置，所述方法包括以下步骤：测量流过患者降主动脉的血液的收缩速度; 确定患者升主动脉的横截面积; 以及从所述收缩速度和所述主动脉区域计算患者的心输出量。心输出量可以通过将其除以患者的体表面积而转化为心脏指数，和（2）通过将表示患者血压的值除以所述心输出量而得到全身血管阻力。

2. 发明授权

US5291879A Carbon dioxide detection (II) 失效
标题翻译：二氧化碳检测（二）
公开(公告)号：US5291879A
公开(公告)日：1994-03-08
申请号：US918372
申请日：1992-07-23
申请人： Albert L. Babb , Michael P. Hlastala , Gary L. Tarbox
发明人： Albert L. Babb , Michael P. Hlastala , Gary L. Tarbox
IPC分类号： A61B5/083 , A61M16/04 , G01N31/22 , A61M16/00
CPC分类号： A61M16/0488 , G01N31/223 , A61B5/0836 , A61M2016/0413
摘要： Methods and apparatus for ascertaining whether there is at least a threshold concentration of carbon dioxide in gases being monitored. Reversible hydration of the carbon dioxide to generate excess hydrogen ions and trigger a color change in a pH sensitive indicator is employed in representative embodiments of the invention to provide an indication that the threshold concentration of carbon dioxide is present in the gases. The methods and apparatus may be used to distinguish between tracheal and esophageal intubation of human and other mammalian patients.
摘要翻译：确定在被监测的气体中是否存在至少二氧化碳的阈值浓度的方法和装置。在本发明的代表性实施例中采用二氧化碳的可逆水合以产生过量的氢离子并引发pH敏感指示剂的颜色变化，以提供二氧化碳的阈值浓度存在于气体中的指示。方法和装置可以用于区分人和其他哺乳动物患者的气管和食管插管。

3. 发明授权

US4509526A Method and system for non-invasive ultrasound Doppler cardiac output measurement 失效
标题翻译：非侵入性超声多普勒心输出量测方法与系统
公开(公告)号：US4509526A
公开(公告)日：1985-04-09
申请号：US464965
申请日：1983-02-08
申请人： Stephen R. Barnes , Gary L. Tarbox , Lee L. Huntsman , Barry D. McLaren
发明人： Stephen R. Barnes , Gary L. Tarbox , Lee L. Huntsman , Barry D. McLaren
IPC分类号： A61B8/06 , G01S15/89 , A61B10/00
CPC分类号： A61B8/463 , A61B8/065 , A61B8/465 , G01S15/8979 , A61B8/4405
摘要： A method and system for the noninvasive measurement of cardiac output of a mammalian patient on a real time, beat-by-beat basis as a combined function of the cross-sectional area of the ascending aorta and the systolic velocity of blood flow therethrough is comprised of the steps of and apparatus for pulsedly insonifying the ascending aorta of the patient with repetitive, intermittent ultrasonic energy propagating through the patient's cardiac window; receiving pulses of ultrasonic energy reflected from the anatomical structure within the first insonification zone, including energy reflected from the aortic walls and characteristic of the dimensional separation thereof; developing an aortic diameter signal indicative of dimensional separation; computing the cross-sectional area of the ascending aorta therefrom; then continuously insonifying the ascending aorta with uninterrupted ultrasonic energy; receiving a Doppler-shifted ultrasonic energy signal reflected from pulsatile blood flow through the ascending aorta, and characteristic of systolic velocity of blood flow; subjecting the systolic velocity signal to a frequency spectrum analysis at a predetermined signal sampling rate to yield a velocity component profile signal; integrating the velocity component profile signal over time; computing systolic volume as a combined function of cross-sectional area and the systolic velocity integral for each of n cardiac cycles; and, computing cardiac output as the time-averaged sum of systolic volumes for the n periods.
摘要翻译：包括作为上升主动脉的横截面面积和通过其的血流的收缩速度的组合函数的实时，逐节拍的非侵入式测量哺乳动物患者心输出量的方法和系统。用于通过患者心脏窗口传播的重复间歇超声波脉冲地使患者的升主动脉脉动化的步骤和装置; 从所述第一增强区域内的所述解剖结构反射的超声能量的脉冲，包括从所述主动脉壁反射的能量和其尺寸分离的特征; 开发指示尺寸分离的主动脉直径信号; 计算升主动脉的横截面面积; 然后用不间断的超声能量不断地上升主动脉; 接收从上升主动脉脉动血流反射的多普勒超声能量信号，以及血流收缩速度的特征; 以收缩速度信号以预定的信号采样率进行频谱分析以产生速度分量分布信号; 随时间整合速度分量分布信号; 计算收缩容积作为横截面积的组合函数和n个心动周期中的每一个的收缩速度积分; 并计算心输出量作为n个周期的收缩期的时间平均和。

4. 发明授权

US5197464A Carbon dioxide detection 失效
标题翻译：二氧化碳检测
公开(公告)号：US5197464A
公开(公告)日：1993-03-30
申请号：US629055
申请日：1990-12-14
申请人： Albert L. Babb , Michael P. Hlastala , Gary L. Tarbox
发明人： Albert L. Babb , Michael P. Hlastala , Gary L. Tarbox
IPC分类号： A61B5/083 , A61M16/04 , G01N31/22
CPC分类号： A61M16/0488 , G01N31/223 , A61B5/0836 , A61M2016/0413
摘要： Methods and apparatus for ascertaining whether there is at least a threshold concentration of carbon dioxide in gases being monitored. Reversible hydration of the carbon dioxide to generate excess hydrogen ions and trigger a color change in a pH sensitive indicator is employed in represenative embodiments of the invention to provide a indication that the threshold concentration of carbon dioxide is present in the gases. The methods and apparatus may be used to distinguish between tracheal and esophageal intubation of human and other nammalian patients.
摘要翻译：确定在被监测的气体中是否存在至少二氧化碳的阈值浓度的方法和装置。在本发明的代表性实施方案中使用二氧化碳的可逆水合以产生过量氢离子并引发pH敏感指示剂的颜色变化，以提供二氧化碳的阈值浓度存在于气体中的指示。方法和装置可用于区分人和其他nammalian患者的气管和食管插管。

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