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1. 发明申请

US20080231268A1 Imaging Method Based on Fractal Surface-Filling or Space-Filling Curves 失效
标题翻译：基于分形表面填充或空间填充曲线的成像方法
公开(公告)号：US20080231268A1
公开(公告)日：2008-09-25
申请号：US10586083
申请日：2004-12-17
申请人： Richard Patzak , Daniel Gembris , Stephan Appelt , Friedrich-Wolfgang Hasing , Horst Halling
发明人： Richard Patzak , Daniel Gembris , Stephan Appelt , Friedrich-Wolfgang Hasing , Horst Halling
IPC分类号： G01R33/48
CPC分类号： G01R33/4822 , G01R33/445 , G01R33/48 , G01R33/4806 , G01R33/5615
摘要： The present invention relates to an imaging method and device for nuclear magnetic resonance. On the one hand, the method provides an image coding by means of an additional field which has, for each point of a two-dimensional grating surface within the sample, a different field strength value that occurs only once, as is the case, e.g., in fields based on fractal, surface-filling and space-filling curves. On the other hand, the read-out of the resonance behavior of a sample along a space-filling and/or surface-filling curve can be provided. In the first variant, a magnetic resonance (MR) image with a single high-frequency excitation without a time-varying gradient can be recorded, which in turn advantageously prevents the sound generation associated therewith. In the second variant, the sounds generated during read-out are advantageously shifted to another frequency range in which the human hearing is less sensitive. Furthermore, the device is relieved and the technical requirements with regard to it are reduced. In addition, it can be executed with known and existing devices.
摘要翻译：本发明涉及用于核磁共振的成像方法和装置。一方面，该方法通过附加场提供图像编码，对于样本内的二维光栅表面的每个点，其具有仅出现一次的不同场强值，例如，，在基于分形，表面填充和空间填充曲线的领域。另一方面，可以提供沿空间填充和/或曲面填充曲线读取样本的共振特性。在第一变型中，可以记录具有不具有时变梯度的单个高频激励的磁共振（MR）图像，这又有利地防止与之相关联的声音生成。在第二变型中，在读出期间产生的声音有利地被移动到人听觉不太敏感的另一个频率范围。此外，该装置得到缓解，并且减少了对其的技术要求。此外，它可以用已知和现有的设备执行。

2. 发明授权

US6087664A Process and device for measuring the radiation depth of radiation 失效
标题翻译：用于测量辐射辐射深度的过程和设备
公开(公告)号：US6087664A
公开(公告)日：2000-07-11
申请号：US11399
申请日：1998-01-29
申请人： Stefan Gripp , Friedrich-Wolfgang Hasing , Harald Buker
发明人： Stefan Gripp , Friedrich-Wolfgang Hasing , Harald Buker
IPC分类号： A61N5/10 , G01T1/06 , G01T5/08 , G01T1/17 , G01T1/185 , G01T1/20
CPC分类号： A61N5/1048 , G01T1/06
摘要： The invention pertains to a measurement device comprising two sensors for measuring radiation doses. The sensors are, for example, optical waveguides aligned along a straight line. One of the optical waveguides covers a longer section along the line than the other waveguide; in particular, the difference is at least 20 mm. Measurement using the measurement device is done as follows: the radiation dose along the line of radiation down to the expected penetration depth is measured using the wider sensor; the narrower sensor is used to determine the radiation dose in a volume element within the radiation path. A quotient is formed from the two measurements and used to calculate the radiation depth on the basis of reference values. The proposed device facilitates rapid and simple determination of a penetration depth of an ionizing radiation, for example in tissue.
摘要翻译： PCT No.PCT / DE96 / 01405 Sec。 371日期1998年1月29日 102（e）1998年1月29日PCT PCT 1996年7月25日PCT公布。出版物WO97 / 05506 日期1997年2月13日本发明涉及包括用于测量辐射剂量的两个传感器的测量装置。传感器例如是沿着直线排列的光波导。光波导中的一个覆盖沿着该线路比另一个波导更长的部分; 特别地，差值至少为20mm。使用测量装置测量如下：使用更宽的传感器测量沿着辐射线的辐射剂量到预期穿透深度; 较窄的传感器用于确定辐射路径内的体积元件中的辐射剂量。一个商由两个测量形成，用于根据参考值计算辐射深度。所提出的装置有助于快速和简单地确定电离辐射的穿透深度，例如在组织中。

3. 发明授权

US07541806B2 Method for molecule examination by NMR spectroscopy 失效
标题翻译：通过NMR光谱分析检测方法
公开(公告)号：US07541806B2
公开(公告)日：2009-06-02
申请号：US11681331
申请日：2007-03-02
申请人： Stephan Appelt , Holger Kuhn , Ulrich Sieling , Friedrich-Wolfgang Hasing
发明人： Stephan Appelt , Holger Kuhn , Ulrich Sieling , Friedrich-Wolfgang Hasing
IPC分类号： G01V3/00
CPC分类号： G01R33/4608 , G01N24/087 , G01R33/383 , G01R33/445 , G01R33/4633 , G01R33/465 , G01R33/5605
摘要： The invention relates to a method and a device for examining molecules by means of NMR spectroscopy. It is the object of the invention to be able to characterize a sample with a high resolution and comprehensively. The object is solved by a method and an associated device for examining a sample by means of nuclear magnetic spectroscopy by measuring heteronuclear and homonuclear J-couplings in a small magnetic field and by using the measured heteronuclear and homonuclear J-couplings for characterizing the sample.
摘要翻译：本发明涉及通过NMR光谱检测分子的方法和装置。本发明的目的是能够以高分辨率和全面地表征样品。该目的通过一种方法和相关设备来解决，用于通过在小磁场中测量异核和同核J耦合并通过使用测量的异核和同核J耦合来表征样品，通过核磁谱检查样品。

4. 发明申请

US20070296412A1 Method For Molecule Examination By NMR Spectroscopy 失效
标题翻译：通过NMR光谱分析检测方法
公开(公告)号：US20070296412A1
公开(公告)日：2007-12-27
申请号：US11681331
申请日：2007-03-02
申请人： Stephan Appelt , Holger Kuhn , Ulrich Sieling , Friedrich-Wolfgang Hasing
发明人： Stephan Appelt , Holger Kuhn , Ulrich Sieling , Friedrich-Wolfgang Hasing
IPC分类号： G01V3/14
CPC分类号： G01R33/4608 , G01N24/087 , G01R33/383 , G01R33/445 , G01R33/4633 , G01R33/465 , G01R33/5605
摘要： The invention relates to a method and a device for examining molecules by means of NMR spectroscopy. It is the object of the invention to be able to characterize a sample with a high resolution and comprehensively. The object is solved by a method and an associated device for examining a sample by means of nuclear magnetic spectroscopy by measuring heteronuclear and homonuclear J-couplings in a small magnetic field and by using the measured heteronuclear and homonuclear J-couplings for characterizing the sample.
摘要翻译：本发明涉及通过NMR光谱检测分子的方法和装置。本发明的目的是能够以高分辨率和全面地表征样品。该目的通过一种方法和相关设备来解决，用于通过在小磁场中测量异核和同核J耦合并通过使用测量的异核和同核J耦合来表征样品，通过核磁谱检查样品。

5. 发明授权

US5938605A Measuring process and sensor for on-line in-vivo determination of the tissue-equivalent dose in radiotherapy 失效
标题翻译：测量过程和传感器，用于在线放射治疗中组织等效剂量的体内测定
公开(公告)号：US5938605A
公开(公告)日：1999-08-17
申请号：US894568
申请日：1997-08-06
申请人： Friedrich-Wolfgang Hasing , Harald Buker
发明人： Friedrich-Wolfgang Hasing , Harald Buker
IPC分类号： G01T1/00 , A61N5/10 , G01T1/02 , G01T1/16 , G01T1/161 , G02B6/02 , H05G1/26 , H05G1/44 , A61B6/00
CPC分类号： H05G1/44 , A61N5/1048 , G01T1/02 , G01T1/161 , G02B6/02 , H05G1/26 , A61B6/583 , G02B6/02042
摘要： A process and measuring device for determining the tissue-equivalent dose in radiotherapy. First, the radiation dose is measured according to the process at a site by at least two sensors i and j. The sensors are designed such that the associated measuring signals S.sub.i and S.sub.j display different energy dependency of the detection sensitivity to ionizing radiation, a dose-independent quotient Q.sub.ij =S.sub.i /S.sub.j being formed from this difference. The tissue-equivalent dose D is then calculated from this dose-independent value. The advantages of this process are that the sensor material does not have to be adapted to the tissue and can therefore be freely selected, and the tissue-equivalent dose is determined highly accurately. The measuring device comprises three parallel fiber-optic sensors disposed equidistant in a plane, the outer sensors being identical and differing from the central sensor by differing energy dependency of the detection sensitivity to ionizing radiation.
摘要翻译： PCT No.PCT / DE96 / 00174 Sec。 371日期：1997年8月6日 102（e）日期1997年8月6日PCT 1996年2月1日PCT公布。第WO96 / 24859号公报日期1996年8月15日用于确定放射治疗组织当量剂量的过程和测量装置。首先，辐射剂量是根据至少两个传感器i和j在现场的过程来测量的。传感器被设计成使得相关联的测量信号Si和Sj显示与电离辐射不同的检测灵敏度的能量依赖性，由该差异形成剂量依赖的商Qij = Si / Sj。然后从该剂量无关值计算组织当量剂量D. 该方法的优点是传感器材料不必适应于组织，因此可以自由选择，并且高度准确地确定组织等效剂量。测量装置包括在平面内等距设置的三个平行光纤传感器，外部传感器与检测灵敏度与电离辐射的能量依赖性不同，与中央传感器不同。

6. 发明授权

US07557574B2 Imaging method based on fractal surface-filling or space-filling curves 失效
$Imaging method based on fractal surface-filling or space-filling curves$
标题翻译：基于分形表面填充或空间填充曲线的成像方法
公开(公告)号：US07557574B2
公开(公告)日：2009-07-07
申请号：US10586083
申请日：2004-12-17
申请人： Richard Patzak , Daniel Gembris , Stephan Appelt , Friedrich-Wolfgang Hasing , Horst Halling
发明人： Richard Patzak , Daniel Gembris , Stephan Appelt , Friedrich-Wolfgang Hasing , Horst Halling
IPC分类号： G01V3/00
CPC分类号： G01R33/4822 , G01R33/445 , G01R33/48 , G01R33/4806 , G01R33/5615
摘要： The present invention relates to an imaging method and device for nuclear magnetic resonance. On the one hand, the method provides an image coding by means of an additional field which has, for each point of a two-dimensional grating surface within the sample, a different field strength value that occurs only once, as is the case, e.g., in fields based on fractal, surface-filling and space-filling curves. On the other hand, the read-out of the resonance behavior of a sample along a space-filling and/or surface-filling curve can be provided. In the first variant, a magnetic resonance (MR) image with a single high-frequency excitation without a time-varying gradient can be recorded, which in turn advantageously prevents the sound generation associated therewith. In the second variant, the sounds generated during read-out are advantageously shifted to another frequency range in which the human hearing is less sensitive. Furthermore, the device is relieved and the technical requirements with regard to it are reduced. In addition, it can be executed with known and existing devices.
摘要翻译：本发明涉及用于核磁共振的成像方法和装置。一方面，该方法通过附加场提供图像编码，对于样本内的二维光栅表面的每个点，其具有仅出现一次的不同场强值，例如，，在基于分形，表面填充和空间填充曲线的领域。另一方面，可以提供沿空间填充和/或曲面填充曲线读取样本的共振特性。在第一变型中，可以记录具有不具有时变梯度的单个高频激励的磁共振（MR）图像，这又有利地防止与之相关联的声音生成。在第二变型中，在读出期间产生的声音有利地被移动到人听觉不太敏感的另一个频率范围。此外，该装置得到缓解，并且减少了对其的技术要求。此外，它可以用已知和现有的设备执行。

7. 发明授权

US6041150A Multipass cavity sensor for measuring a tissue-equivalent radiation dose 失效
标题翻译：用于测量组织等效辐射剂量的多孔腔传感器
公开(公告)号：US6041150A
公开(公告)日：2000-03-21
申请号：US77819
申请日：1998-06-01
申请人： Friedrich Wolfgang Hasing , Frank Pfeiffer , Harald Buker
发明人： Friedrich Wolfgang Hasing , Frank Pfeiffer , Harald Buker
IPC分类号： G01T1/06 , G01T5/08 , G02B6/00
CPC分类号： G01T5/08 , G01T1/06
摘要： A sensor for a tissue-equivalent radiation dose comprises a light waveguide sensitive to radiation and in a field of radiation. The waveguide is mirrored at both ends so that the back and forth passage of light takes place a multiplicity of times and a light waveguide acts as a multipath cavity. The light is coupled into and out of the waveguide at an end thereof and the ends of the waveguide can be pointed.
摘要翻译： PCT No.PCT / DE96 / 02321 Sec。 371日期1998年6月1日 102（e）1998年6月1日PCT 1996年12月2日PCT PCT。第WO97 / 21112号公报日期1997年6月12日用于组织等效辐射剂量的传感器包括对放射线和辐射场敏感的光波导。波导在两端被镜像，使得光的前后通过发生多次，并且光波导用作多径腔。该光在波导的一端耦合入和离开波导，波导的端部可以是尖的。

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