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    • 3. 发明申请
    • Electro-optical cell
    • 电光电池
    • US20070024950A1
    • 2007-02-01
    • US10596871
    • 2005-01-05
    • Nynke VerhaeghDirk De BoerLucas SchlangenBas Van Der HeijdenMark Johnson
    • Nynke VerhaeghDirk De BoerLucas SchlangenBas Van Der HeijdenMark Johnson
    • G02B26/00
    • G02F1/172G02F1/13718G02F2001/134381G02F2201/343
    • The invention relates to an electro-optical cell (1) comprising a first (2) and a second (3) support member, an electro-optical medium (5) between the support members and an electrode arrangement (11, 12) on the support members such that an electric field can be applied, in the electro-optical medium, perpendicular to the support members, aligned with the support members or at an oblique angle (7) with respect to the support members. The electro-optical cell further comprises layers (14) of material with different dielectric constant between the support members in order to reduce the inhomogeneity of the electric field lines in the electro-optical medium. By having a layer of cholesteric liquid crystals between the support members, the electro-optical cell will function as a colour filter for varying applied fields. By introducing a particle suspension in a medium between the support members, an electro-optical cell is created that can be switched between a transmissive, reflective and partly deflective state.
    • 本发明涉及一种包括第一(2)和第二(3)支撑构件的电光学电池(1),在支撑构件之间的电光介质(5)和电极装置(11,12) 支撑构件,使得可以在电光介质中垂直于支撑构件施加电场,与支撑构件对准或者相对于支撑构件以倾斜角度(7)施加电场。 电光电池还包括在支撑构件之间具有不同介电常数的材料层(14),以便减少电光介质中电场线的不均匀性。 通过在支撑构件之间具有胆甾型液晶层,电光单元将用作用于改变施加场的滤色器。 通过在支撑构件之间的介质中引入颗粒悬浮液,产生可以在透射,反射和部分偏转状态之间切换的电光单元。
    • 4. 发明申请
    • Electrooptic/micromechanical display with discretely controllable bistable transflector
    • 具有离散控制双稳态透射反射器的电光/微机械显示
    • US20060290651A1
    • 2006-12-28
    • US10572843
    • 2004-09-09
    • Nynke VerhaeghDirk De BoerMark JohnsonBas Van Der Heijden
    • Nynke VerhaeghDirk De BoerMark JohnsonBas Van Der Heijden
    • G09G3/34
    • G02F1/133555G02F1/15G02F1/167G02F1/172G02F1/19
    • A display (1) comprises a display device (2), such as an LC cell and a switchable transflector (7). The transflector 7 comprises a plurality of discrete portions and is configured so that the transmittance and reflectance properties of at least one of said portions can be tuned independently of other portions. Where the transflector is a suspended particle device (SPD), the portions may comprise individual particle suspensions (8a, 8b, 8c) and/or regions within a cell containing a particle suspension (8a, 8b, 8c). In normal operation, images etc. are displayed using the display device (2). In some embodiments, the transflector (7) may be used in the provision of illumination for the display device (2) using backlighting 9 from light source (3) and/or reflected ambient light (10), in dependence on the light level detected by a light sensor (22). The transflector 7 may be used to display images (23) or text, such as touch screen keys (24) while the display (1) is in standby mode and the display device (2) is switched off.
    • 显示器(1)包括诸如LC单元和可切换透镜(7)之类的显示设备(2)。 透射反射器7包括多个离散部分,并且被配置为使得可以独立于其它部分来调谐至少一个所述部分的透射率和反射率特性。 当透射反射器是悬浮颗粒装置(SPD)时,这些部分可以包含单个颗粒悬浮液(8a,8b,8c)和/或含有颗粒悬浮液(8a,8b,8c)的细胞内的区域, 。 在正常操作中,使用显示装置(2)显示图像等。 在一些实施例中,透射反射器(7)可以用于根据检测到的光电平使用来自光源(3)和/或反射环境光(10)的背光9向显示装置(2)提供照明 通过光传感器(22)。 当显示器(1)处于待机模式并且显示设备(2)被关闭时,透射反射器7可用于显示图像(23)或文本,例如触摸屏键(24)。
    • 7. 发明申请
    • Switchable transflector and transflective display
    • 可切换透镜和透反射显示器
    • US20070159678A1
    • 2007-07-12
    • US10572841
    • 2004-09-10
    • Nynke VerhaeghDirk De BoerMark JohnsonBas Van Der Heijden
    • Nynke VerhaeghDirk De BoerMark JohnsonBas Van Der Heijden
    • G02F1/15
    • G02F1/172G02F1/133555G02F2001/134381
    • A switchable transflector (1) comprises a suspended particle device (SPD). The transflector (1) may be switched into transmissive, reflective or intermediate states by applying one or more electric fields to a particle suspension (2). An enhanced reflectivity state may be achieved by applying two mutually orthogonal electric fields simultaneously. An intermediate state may be achieved by applying a non-saturating electric field or by applying two or more electric fields alternately according to a timing scheme. The transflector (1) may be maintained in a given state by applying voltage pulses at intervals less than a relaxation time associated with the SPD 1. The transmittance and reflectance properties of the transflector (1) may be tuned in accordance with the output of a light sensor (14). The transflector (1) may be incorporated in a transflective display (15)which comprises a display device, such as an LCD (16). In order to illuminate the LCD (16), the transflector (1) is arranged to transmit light (20) emitted by a light source (17) and/or reflect ambient light (21). The relative proportions of transmitted and reflected illumination may be determin by the output of the light sensor (14).
    • 可切换透镜(1)包括悬浮颗粒装置(SPD)。 透射反射器(1)可以通过将一个或多个电场施加到颗粒悬浮液(2)而转换成透射的,反射的或中间的状态。 可以通过同时施加两个相互正交的电场来实现增强的反射率状态。 可以通过施加非饱和电场或者根据定时方案交替地施加两个或更多个电场来实现中间状态。 可以通过以小于与SPD 1相关联的松弛时间的间隔施加电压脉冲来将透射反射器(1)保持在给定状态。 可以根据光传感器(14)的输出来调节透射反射器(1)的透射率和反射率特性。 半导体器件(1)可以结合在包括诸如LCD(16)的显示装置的透反射显示器(15)中。 为了照亮LCD(16),透射反射器(1)被布置成透射由光源(17)发射的光(20)和/或反射环境光(21)。 透射和反射照明的相对比例可以由光传感器(14)的输出来确定。
    • 9. 发明授权
    • Diazabicyclo alkane derivatives with NK1 antagonistic activity
    • 具有NK1拮抗活性的二氮杂双环烷烃衍生物
    • US07202238B2
    • 2007-04-10
    • US10490364
    • 2003-04-02
    • Dirk de BoerHein K. A. C. CoolenMayke B. HesselinkWouter I. Iwema BakkerGijsbert D. KuilJan H. van MaarseveenAndrew C. McCrearyGustaaf J. M. van Scharrenburg
    • Dirk de BoerHein K. A. C. CoolenMayke B. HesselinkWouter I. Iwema BakkerGijsbert D. KuilJan H. van MaarseveenAndrew C. McCrearyGustaaf J. M. van Scharrenburg
    • A01N43/00A01N43/58A01N43/50A61K31/55C07D241/36
    • C07D471/04C07D487/04
    • The present invention relates to a group of unique diazabicyclo alkane derivatives having interesting neurokinin-NK1 receptor antagonistic activity represented by the general formula (1) wherein: R1 represents phenyl, 2-indolyl, 3-indolyl, 3-indazolyl or benzo[b]thiophen-3-yl, which groups may be substituted with halogen or alkyl (1–3C), R2 and R3 independently represent halogen, H, OCH3, CH3 and CF3, R4, R5 and R6 independently represent H, OH, O-alkyl(1–4C), CH2OH, NH2, dialkyl(1–3C)N, pyrrolidin-1-yl, piperidin-1-yl, morpholin-4-yl or morpholin-4-yl substituted with one or two methyl or methoxymethyl groups, morpholin-4-ylamino, morpholin-4-ylmethyl, imidazol-1-yl, thiomorpholin-4-yl, 1,1-dioxothiomorpholin-4-yl or 3-oxa-8-azabicyclo[3.2.1]oct-8-yl; R4 and R5 together may represent a keto, a 1,3-dioxan-2-yl or a 1,3-dioxolan-2-yl group, X represents either O or S, n has the value of 1, 2 or 3, a is the asymmetrical carbon atom 8a, 9a or 10a when n equals 1, 2 or 3 respectively The invention also relates to a method for the preparation of the novel compounds, and to pharmaceutical compositions containing at least one of these compounds as an active ingredient
    • 本发明涉及具有由通式(1)表示的具有感兴趣的神经激肽NK 1受体拮抗作用的独特的二氮杂双环烷烃衍生物组,其中:R 1表示苯基, 2-吲哚基,3-吲哚基,3-吲唑基或苯并[b]噻吩-3-基,该基团可被卤素或烷基(1-3C),R 2和R 2 > 3个独立地表示卤素,H,OCH 3,CH 3和CF 3,R 4, >,R 5和R 6独立地表示H,OH,O-烷基(1-4C),CH 2 OH,NH (1-3C)N,吡咯烷-1-基,哌啶-1-基,吗啉-4-基或被一个或两个甲基或甲氧基甲基取代的吗啉-4-基,吗啉代 - 吡啶-4-基氨基,吗啉-4-基甲基,咪唑-1-基,硫代吗啉-4-基,1,1-二氧代硫代吗啉-4-基或3-氧杂-8-氮杂双环[3.2.1]辛-8-基; R 4和R 5一起可以表示酮基,1,3-二氧杂环戊烷-2-基或1,3-二氧戊环-2-基,X表示 O或S,n的值为1,2或3,当n分别为1,2或3时,a为非对称碳原子8a,9a或10a。本发明还涉及一种制备新化合物的方法 以及含有这些化合物中的至少一种作为活性成分的药物组合物
    • 10. 发明申请
    • Display device with suspended anisometric particles
    • 具有悬挂的不等轴微粒的显示装置
    • US20070070489A1
    • 2007-03-29
    • US10572838
    • 2004-09-09
    • Nynke VerhaeghDirk De BoerMark JohnsonBas Van Der Heijden
    • Nynke VerhaeghDirk De BoerMark JohnsonBas Van Der Heijden
    • G02F1/15
    • G02F1/172G02F2201/12G02F2203/12
    • A suspended particle device (SPD) 4 comprises at least one compartment for housing a particle suspension 1Oa, 1Ob, means for applying a first electric field to the particle suspension IOa, 1 Ob and means for applying a second electric field to the particle suspension 10a, 10b, the first and second electric fields having different field directions. A plurality of pixels are defined by a plurality of compartments, each housing a separate particle suspension 10a, 10b and/or regions of a particle suspension 10 within a compartment in which means for applying an inhomogeneous second electric field are provided (FIG. 11). Each pixel may be tuned to a transmissive state, a reflective state or an intermediate state or “grey value”, so that the SPD 4 may be used to display imaging or text. The SPD 4 may be reset by bringing the pixels into the same state by applying an appropriate electric field to one or more pixels.
    • 悬浮颗粒装置(SPD)4包括至少一个用于容纳颗粒悬浮液10a的室,10b,用于向颗粒悬浮液10a施加第一电场的装置,以及用于向颗粒施加第二电场的装置 悬架10a,10b,第一和第二电场具有不同的场方向。 多个像素由多个隔室限定,每个隔室容纳单独的颗粒悬浮液10a,10b和/或在其中提供用于施加不均匀的第二电场的装置的颗粒悬浮液10的区域。 11)。 可以将每个像素调整到透射状态,反射状态或中间状态或“灰度值”,使得SPD4可用于显示成像或文本。 可以通过将适当的电场施加到一个或多个像素来使像素进入相同的状态来复位SPD 4。