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1. 发明申请

US20130231593A1 NON-INVASIVE SYSTEM TO REGULATE INTRACRANIAL PRESSURE 审中-公开
标题翻译：非侵入式系统来调节压力
公开(公告)号：US20130231593A1
公开(公告)日：2013-09-05
申请号：US13782913
申请日：2013-03-01
申请人： Demetris Yannopoulos , Keith G. Lurie
发明人： Demetris Yannopoulos , Keith G. Lurie
IPC分类号： A61H9/00
CPC分类号： A61H9/00 , A61H31/02 , A61M16/0009 , A61M16/0084 , A61M16/06 , A61M16/0866 , A61M16/20 , A61M16/209
摘要： A method is provided for non-invasively lowering a person's ICP and increasing cerebral perfusion pressure. The method may include the step of actively lowering the person's intrathoracic pressure. Also, the person's effective circulating blood volume is lowered while the person's intrathoracic pressure is lowered to thereby non-invasively reduce venous blood volume in the brain to treat elevated intracranial pressure.
摘要翻译：提供一种不侵入性地降低人的ICP和增加脑灌注压力的方法。该方法可以包括积极降低人的胸内压力的步骤。此外，人的有效循环血容量降低，同时人体内的胸内压力降低，从而非侵入性地减少脑中的静脉血容量以治疗升高的颅内压。

2. 发明申请

US20120330200A1 ENHANCED GUIDED ACTIVE COMPRESSION DECOMPRESSION CARDIOPULMONARY RESUSCITATION SYSTEMS AND METHODS 有权
标题翻译：增强引导主动压缩解体心脏复苏系统和方法
公开(公告)号：US20120330200A1
公开(公告)日：2012-12-27
申请号：US13554986
申请日：2012-07-20
申请人： Greg Voss , Anja Metzger , Keith Lurie , Demetris Yannopoulos
发明人： Greg Voss , Anja Metzger , Keith Lurie , Demetris Yannopoulos
IPC分类号： A61H31/00
CPC分类号： A61H31/004 , A61H31/005 , A61H31/006 , A61H2201/5043 , A61H2201/5061 , A61H2201/5064 , A61H2201/5084 , A61H2230/207 , A61H2230/42 , A61H2230/50
摘要： Systems and methods for applying enhanced guided active compression decompression cardiopulmonary resuscitation are provided. Exemplary systems include a load cell, a handle, an adhesive pad. The handle and the adhesive pad are configured for magnetic coupling.
摘要翻译：提供了应用增强的导向有效压缩减压心肺复苏的系统和方法。示例性系统包括测力传感器，手柄，粘合垫。手柄和粘合垫被配置用于磁耦合。

3. 发明申请

US20120203147A1 VASODILATOR-ENHANCED CARDIOPULMONARY RESUSCITATION 审中-公开
标题翻译：血管扩张剂 - 增强心脏电除颤
公开(公告)号：US20120203147A1
公开(公告)日：2012-08-09
申请号：US13175670
申请日：2011-07-01
申请人： Keith Lurie , Demetris Yannopoulos
发明人： Keith Lurie , Demetris Yannopoulos
IPC分类号： A61H31/00 , A61K33/26 , A61K31/21 , A61K31/343 , A61P9/04 , A61K31/4985 , A61K31/53 , A61K31/7076 , A61K31/522 , G09B23/28 , A61K31/519
CPC分类号： A61K33/26 , A61H31/004 , A61K31/21 , A61K31/34 , A61K31/4985 , A61K31/519 , A61K31/522 , A61K31/7076 , A61M16/024
摘要： A method for increasing blood flow to vital organs during cardiopulmonary resuscitation of a person experiencing a cardiac arrest may include performing standard or active compression decompression cardiopulmonary resuscitation on a person to create artificial circulation by repetitively compressing the person's chest such that the person's chest is subject to a compression phase and a relaxation or decompression phase. The method may also include administering one or more vasodilator drugs to the person to improve the artificial circulation created by the cardiopulmonary resuscitation. The method may also include binding at least a portion of the person's abdomen, either manually or with an abdominal compression device. Performing cardiopulmonary resuscitation on a person may include ventilating the person with either an impedance threshold device or a intrathoracic pressure regulator.
摘要翻译：在经历心跳停止的人的心肺复苏期间增加对重要器官的血液流量的方法可包括对人进行标准的或主动的压缩减压心肺复苏，以通过重复地压缩人的胸部以使人的胸部受到压缩阶段和松弛或减压阶段。该方法还可以包括向人施用一种或多种血管扩张剂药物以改善由心肺复苏产生的人造循环。该方法还可以包括手动地或用腹部压缩装置绑定人的腹部的至少一部分。对人进行心肺复苏可以包括使用阻抗阈值装置或胸腔内压力调节器来呼吸该人。

4. 发明申请

US20170333671A1 THERMODILUTION CATHETER 审中-公开
公开(公告)号：US20170333671A1
公开(公告)日：2017-11-23
申请号：US15602733
申请日：2017-05-23
申请人： Matthew D. Olson , Demetris Yannopoulos , Jason Bartos
发明人： Matthew D. Olson , Demetris Yannopoulos , Jason Bartos
IPC分类号： A61M25/00 , A61B5/028 , A61M25/09 , A61M29/02 , A61B5/01 , A61M25/10 , A61B5/00
CPC分类号： A61M25/007 , A61B5/01 , A61B5/028 , A61B5/029 , A61B5/6853 , A61M25/09 , A61M25/10 , A61M29/02 , A61M2025/0004 , A61M2230/04 , A61M2230/50
摘要： A system includes an outer catheter and an inner catheter. The outer catheter has a proximal end and a distal end. The distal end has a discharge nozzle, a tapered interior wall, and an end orifice. The proximal end is configured to receive a fluid. The discharge nozzle is coupled to the proximal end by a first lumen. The discharge nozzle is configured to direct the fluid in a plurality of discrete streams aligned in a radial fashion about an axis of the first lumen. The interior catheter is configured for placement within the first lumen. A first end of the interior catheter includes an occluder and includes a first temperature sensor. The first temperature sensor is configured to pass through the end orifice. The occluder is configured to engage with the tapered interior wall in a fluid-tight seal. The first temperature sensor includes a sense surface and includes a signal node. The signal node is configured to provide a first signal corresponding to a timewise change in temperature at the sense surface.

5. 发明申请

US20090062701A1 LOWER EXTREMITY COMPRESSION DEVICES, SYSTEMS AND METHODS TO ENHANCE CIRCULATION 审中-公开
标题翻译：较低的极限压缩装置，系统和加强循环的方法
公开(公告)号：US20090062701A1
公开(公告)日：2009-03-05
申请号：US12165366
申请日：2008-06-30
申请人： Demetris Yannopoulos , Keith Lurie
发明人： Demetris Yannopoulos , Keith Lurie
IPC分类号： A61H31/00 , A61M16/20
CPC分类号： A61H31/006 , A61H9/0078 , A61H31/005 , A61H2201/013 , A61H2201/0214 , A61H2201/0242 , A61H2201/5002 , A61H2201/5007 , A61H2201/501 , A61H2201/5035 , A61H2201/5043 , A61H2201/5046 , A61H2201/5048 , A61H2230/04 , A61H2230/205 , A61H2230/207 , A61H2230/25 , A61H2230/30 , A61H2230/50 , A61M16/024
摘要： Systems and methods for enhancing circulation are described. In one particular embodiment, the invention provides a method for enhancing circulation. The method comprises attaching at least one compression device to at least a portion of a person's lower extremity. The person's chest is repetitively compressed so that the chest experiences a compression phase and a recoil phase or decompression. Also, the person's lower extremity is compressed using the compression device during at least some of the recoil phases.
摘要翻译：描述了用于增强循环的系统和方法。在一个具体实施方案中，本发明提供了一种增强循环的方法。该方法包括将至少一个压缩装置附接到人的下肢的至少一部分。人的胸部被重复压缩，使得胸部经历压缩阶段和反冲阶段或减压。此外，在至少一些反冲阶段期间，使用压缩装置对人的下肢进行压缩。

6. 发明授权

US09724266B2 Enhanced guided active compression decompression cardiopulmonary resuscitation systems and methods 有权
公开(公告)号：US09724266B2
公开(公告)日：2017-08-08
申请号：US13554986
申请日：2012-07-20
申请人： Gregg Voss , Anja Metzger , Keith Lurie , Demetris Yannopoulos
发明人： Gregg Voss , Anja Metzger , Keith Lurie , Demetris Yannopoulos
IPC分类号： A61H31/00
CPC分类号： A61H31/004 , A61H31/005 , A61H31/006 , A61H2201/5043 , A61H2201/5061 , A61H2201/5064 , A61H2201/5084 , A61H2230/207 , A61H2230/42 , A61H2230/50
摘要： Systems and methods for applying enhanced guided active compression decompression cardiopulmonary resuscitation are provided. Exemplary systems include a load cell, a handle, an adhesive pad. The handle and the adhesive pad are configured for magnetic coupling.

7. 发明申请

US20140363391A1 SYSTEM AND METHOD FOR ADMINISTERING POLOXAMERS AND ANESTHETICS WHILE PERFORMING CPR AND MINIMIZING REPERFUSION INJURY 审中-公开
标题翻译：在执行CPR并最小化再灌注损伤时管理POLOXAMERS和ANESTHETICS的系统和方法
公开(公告)号：US20140363391A1
公开(公告)日：2014-12-11
申请号：US14297976
申请日：2014-06-06
申请人： Demetris Yannopoulos , Keith G. Lurie
发明人： Demetris Yannopoulos , Keith G. Lurie
IPC分类号： A61K31/77 , A61H31/00 , A61K45/06
CPC分类号： A61K31/77 , A61H31/004 , A61K31/08 , A61K45/06 , A61K2300/00
摘要： According to an embodiment, a system for delivering a synthetic surfactant and an anesthetic to an individual to reduce reperfusion injury includes an anesthetic delivery device and a device for administering the synthetic surfactant intravenously or intraosseously. The anesthetic delivery device includes a patient connection mechanism for coupling with an airway of the individual, an intrathoracic pressure regulation (IPR) mechanism that involves changing the pressure in the airway that is coupled with the patient connection mechanism, and an anesthetic delivery mechanism for receiving the anesthetic and for delivering the anesthetic to the individual via the patient connection mechanism.
摘要翻译：根据一个实施方案，用于将合成表面活性剂和麻醉剂递送给个体以减少再灌注损伤的系统包括麻醉剂递送装置和用于静脉内或口服给予合成表面活性剂的装置。麻醉输送装置包括用于与个体的气道连接的患者连接机构，包括改变与患者连接机构联接的气道中的压力的胸膜内压力调节（IPR）机构，以及用于接收的麻醉剂输送机构麻醉剂和通过患者连接机构将麻醉剂递送给个体。

8. 发明申请

US20140048061A1 SYSTEM AND METHOD FOR ADMINISTERING ANESTHETICS WHILE PERFORMING CPR 审中-公开
标题翻译：在执行CPR时管理麻醉的系统和方法
公开(公告)号：US20140048061A1
公开(公告)日：2014-02-20
申请号：US13964882
申请日：2013-08-12
申请人： Demetris Yannopoulos , Keith G. Lurie
发明人： Demetris Yannopoulos , Keith G. Lurie
IPC分类号： A61H31/00 , A61M5/00 , A61N1/39 , A61M16/01 , A61M11/00
CPC分类号： A61H31/00 , A61H31/004 , A61M5/00 , A61M16/0093 , A61M16/01 , A61M16/1055 , A61M16/107 , A61M16/18 , A61M16/22 , A61N1/39
摘要： According to one embodiment, a device for delivering an anesthetic to an individual to reduce reperfusion injury during the performance of cardiopulmonary resuscitation (CPR) is provided. The device includes a patient connection mechanism for coupling with an airway of the individual and an anesthetic delivery mechanism for receiving the anesthetic and for delivering the anesthetic to the individual via the patient connection mechanism. In some embodiments, the anesthetic is delivered with the assistance of an intrathoracic pressure regulation (IPR) mechanism or an impedance threshold device (ITD) coupled with the patient connection mechanism. The IPR mechanism may be configured to change a pressure in the airway and a thorax of the individual via application of a vacuum source. The ITD device may be configured to prevent respiratory gases from entering the lungs for at least some time during a decompression or relaxation phase of CPR.
摘要翻译：根据一个实施例，提供了一种用于在人肺复苏（CPR）进行期间将麻醉剂输送给个人以减少再灌注损伤的装置。该装置包括用于与个体的气道联接的患者连接机构和用于接收麻醉剂并经由患者连接机构将麻醉剂输送给个体的麻醉剂输送机构。在一些实施方案中，麻醉剂在与患者连接机构耦合的胸腔内压力调节（IPR）机制或阻抗阈值装置（ITD）的帮助下递送。 IPR机构可以被配置为通过施加真空源来改变个体的气道和胸部的压力。 ITD装置可以被配置为在CPR的减压或松弛阶段期间至少一段时间内防止呼吸气体进入肺部。

9. 发明申请

US20120330199A1 METHODS AND SYSTEMS FOR REPERFUSION INJURY PROTECTION AFTER CARDIAC ARREST 审中-公开
标题翻译：心脏损伤后再灌注损伤保护的方法与系统
公开(公告)号：US20120330199A1
公开(公告)日：2012-12-27
申请号：US13554458
申请日：2012-07-20
申请人： Keith Lurie , Demetris Yannopoulos
发明人： Keith Lurie , Demetris Yannopoulos
IPC分类号： A61H31/00
CPC分类号： A61H9/0078 , A61H31/004 , A61H31/005 , A61H31/006 , A61H2201/0214 , A61H2201/105 , A61H2201/1246 , A61H2201/5005 , A61H2230/305 , A61K31/7076 , A61K33/26
摘要： A method is provided for resuscitating a patient from cardiac arrest. This may be done by (a) performing chest compressions for a first period of time at a depth of between about 1.5 to about 3 inches, and (b) ceasing chest compressions for a second period of time. Steps (a) and (b) may be repeated at least two times in order to prevent reperfusion injury after cardiac arrest.
摘要翻译：提供了一种用于使患者从心脏骤停复苏的方法。这可以通过（a）在约1.5至约3英寸之间的深度执行胸部按压第一时间段，以及（b）在第二时间段内停止胸部按压。步骤（a）和（b）可重复至少两次，以防止心脏骤停后的再灌注损伤。

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