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    • 2. 发明申请
    • COMPOSITION I-II AND PRODUCTS AND USES THEREOF
    • 组合物I-II及其制品及其用途
    • US20130310781A1
    • 2013-11-21
    • US13989569
    • 2011-11-25
    • Marcus Damian PhillipsDelphine Blanc
    • Marcus Damian PhillipsDelphine Blanc
    • A61L26/00A61F13/02A61L24/00
    • A61L26/0095A61F13/0216A61L15/26A61L15/425A61L15/585A61L24/0073A61M1/0088C08G77/12C08G77/20C08L83/04C08L83/00
    • A curable composition apportioned between at least one Part A and at least one Part B, the Parts sealed within barrier means preventing contamination, the at least one Part A comprising: (i) one or more alkenyl-group containing prepolymers having at least one alkenyl group or moiety per molecule, and the at least one Part B comprising: (ii) one or more SiH-containing prepolymers having at least one Si—H unit per molecule; the composition additionally comprising: (iii) a catalyst for curing by addition of alkenyl-containing prepolymer (i) to SiH-containing prepolymer (ii), wherein prepolymer (ii) is substantially absent from Part A and prepolymer (i) is substantially absent from Part B, methods for preparing the composition, methods for sterilisation thereof, medical and non-medical use thereof, a device incorporating the composition, and a precursor therefor including its sterilisable precursor composition, in particular a terminally sterilisable or terminally sterile composition for medical use, particularly in wound therapy, more particularly as a wound packing material which can be shaped and configured to the shape of a wound, most particularly for application in negative pressure wound therapy (NPWT).
    • 在至少一个部分A和至少一个部分B之间分配的可固化组合物,密封在屏障内的部分意味着防止污染,所述至少一个部分A包含:(i)一种或多种含链烯基的预聚物,其具有至少一个烯基 每个分子的基团或部分,和至少一个部分B,其包含:(ii)每分子具有至少一个Si-H单元的一种或多种含SiH的预聚物; 所述组合物另外包含:(iii)通过向含SiH的预聚物(ii)中加入含烯基的预聚物(i)固化的催化剂,其中预聚物(ii)基本上不在部分A中,预聚物(i)基本上不存在 来自B部分的方法,用于制备组合物的方法,其灭菌方法,医疗和非医疗用途,包含该组合物的装置及其前体,包括其可灭菌的前体组合物,特别是用于医疗的可灭菌的或终末无菌的组合物 特别是在伤口治疗中,特别是作为伤口包装材料,其可被成形和构造成伤口形状,特别适用于负压伤口治疗(NPWT)。