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    • 7. 发明授权
    • 1-arylpyrazoles and their use as pesticide
    • 1-芳基吡唑及其作为农药的用途
    • US08097732B2
    • 2012-01-17
    • US11764255
    • 2007-06-18
    • David T. ChouMichael MaierFriederike PetryWerner Knauf
    • David T. ChouMichael MaierFriederike PetryWerner Knauf
    • C07D231/00A61K31/415
    • C07D411/04A01N43/56C07D409/04C07D409/14A01N25/006A01N2300/00
    • Disclosed are compounds of formula (I) or pesticidally acceptable salts thereof, wherein, for example, W is ═N—, ═CH—, ═CR7— or ═C(NR8R9)—, R7 is halogen, R8 and R9 are independently of one another hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocyclyl, aralkyl or heterocyclylalkyl, R1 is cyano, halogen, haloalkyl or CS NH2, R2 is alkyl or cycloalkyl, R3 is hydrogen, alkyl or cycloalkyl, R4 is hydrogen, alkyl or cycloalkyl, R5 is haloalkyl, haloalkoxy, halogen or —SF5, R6 is hydrogen, halogen, haloalkyl, nitro or NR16R17, R16 and R17 are independently of one another hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocyclyl, aralkyl or heterocyclylalkyl, X is —S—, —SO—, or —SO2—, Y is —O—, —S—, —SO—, or SO2—, Z is hydrogen, halogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocyclyl, aralkyl, heterocyclylalkyl or NR18R19, and R18 and R19 are hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocyclyl, aralkyl, heterocyclylalkyl. These compounds can be used for controlling pests, especially by treatment of domestic animals.
    • 公开了式(I)化合物或其农药上可接受的盐,其中例如W为= N - , - CH-,= CR7-或= C(NR8R9) - ,R7为卤素,R8和R9独立地为 另一个是氢,烷基,烯基,炔基,环烷基,芳基,杂环基,芳烷基或杂环基烷基,R1是氰基,卤素,卤代烷基或CSNH2,R2是烷基或环烷基,R3是氢,烷基或环烷基,R4是氢, 或环烷基,R5是卤代烷基,卤代烷氧基,卤素或-SF5,R6是氢,卤素,卤代烷基,硝基或NR16R17,R16和R17彼此独立地是氢,烷基,烯基,炔基,环烷基,芳基,杂环基,芳烷基或 杂环基烷基,X是-S-,-SO-或-SO 2 - ,Y是-O - , - S - , - SO-或SO 2 - ,Z是氢,卤素,烷基,烯基,炔基,环烷基,芳基 ,杂环基,芳烷基,杂环基烷基或NR18R19,R18和R19是氢,烷基,烯基,炔基,环烷基,芳基,杂环基,芳烷基, 烯环烷基。 这些化合物可用于防治害虫,特别是通过对家畜进行处理。
    • 10. 发明授权
    • Pesticidal 1-(2-pyridyl)-pyrazole
    • 杀虫剂1-(2-吡啶基) - 吡唑
    • US5306694A
    • 1994-04-26
    • US79221
    • 1993-06-17
    • Jennifer L. PhillipsPhilip R. TimmonsGail S. PowellMichael T. PilatoDavid T. ChouJamin Huang
    • Jennifer L. PhillipsPhilip R. TimmonsGail S. PowellMichael T. PilatoDavid T. ChouJamin Huang
    • A01N43/56A01N43/40A01P5/00A01P7/02A01P7/04C07D213/04C07D213/72C07D231/14C07D401/04C07D401/00
    • C07D401/04
    • The invention describes novel 1-(2-pyridyl)pyrazoles of formula (I) ##STR1## wherein typically preferred substituents are: X is S(O).sub.n R.sub.1, in which R.sub.1 is an alkyl group, preferably a methyl group, which is fully substituted by halogen atoms, and n is 0, 1 and 2;Y is hydrogen, halogen, cyano, alkylsulfenyl, alkylsulfinyl, alkylsulfonyl, alkoxy, amino, alkylamino, dialkylamino, trialkylammonium salt, cyanoalkylamino, alkoxyalkylamino, alkoxycarbonylamino, alkylcarbonylamino, haloalkylcarbonylamino, alkylaminocarbonylamino, dialkylaminocarbonylamino or alkoxyalkylideneimino, wherein the alkyl and alkoxy moieties are a linear or branched chain, containing one to four carbon atoms, and the halo-substitution consists of one or more halogen atoms, which are the same or different, up to full substitution of the alkyl moiety;Z is cyano; andR.sub.2, R.sub.3, R.sub.4, and R.sub.5 are individually hydrogen, halogen or an unsubstituted or halo-substituted alkyl or alkoxy, cyano or nitro; with the proviso that at least one of R.sub.2 to R.sub.5 is other than hydrogen.The invention further describes intermediates and processes to make the compounds, compositions of the compounds, and methods of use of the compounds for the control of arthropods (mites, aphids or insects), nematodes, helminths, or protozoa.
    • 本发明描述了式(I)的新颖的1-(2-吡啶基)吡唑其中通常优选的取代基是:X是S(O)n R 1,其中R 1是烷基,优选甲基, 其完全被卤素原子取代,n为0,1和2; Y是氢,卤素,氰基,烷基亚磺酰基,烷基亚磺酰基,烷基磺酰基,烷氧基,氨基,烷基氨基,二烷基氨基,三烷基铵盐,氰基烷基氨基,烷氧基烷基氨基,烷氧基羰基氨基,烷基羰基氨基,卤代烷基羰基氨基,烷基氨基羰基氨基,二烷基氨基羰基氨基或烷氧基亚烷基亚氨基亚氨基,其中烷基和烷氧基部分是直链 或支链,并且卤素取代由一个或多个相同或不同的卤素原子组成,直至烷基部分的完全取代; Z是氰基; 且R 2,R 3,R 4和R 5分别为氢,卤素或未取代或卤素取代的烷基或烷氧基,氰基或硝基; 条件是R 2至R 5中的至少一个不是氢。 本发明进一步描述了制备化合物,化合物组合物的中间体和方法以及化合物用于控制节肢动物(螨虫,蚜虫或昆虫),线虫,蠕虫或原生动物的方法。