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1. 发明申请

US20140017665A1 ORGAN TRANSPORTER WITH OXYGEN GENERATION 审中-公开
标题翻译：具有氧气生成的有机运输机
公开(公告)号：US20140017665A1
公开(公告)日：2014-01-16
申请号：US13545514
申请日：2012-07-10
申请人： Christopher P. STEINMAN , David KRAVITZ , Aaron R. FERBER , Ross LOCKWOOD , Rodney H. MONSON , Evan D. SHAPIRO
发明人： Christopher P. STEINMAN , David KRAVITZ , Aaron R. FERBER , Ross LOCKWOOD , Rodney H. MONSON , Evan D. SHAPIRO
IPC分类号： A01N1/02
CPC分类号： A01N1/0247
摘要： An apparatus for perfusing an organ or tissue includes a perfusion circuit for perfusing the organ or tissue; an oxygenator for oxygenating perfusate that circulates through the perfusion circuit; and an oxygen supply device such as an oxygen concentrator or an oxygen generator configured to supply oxygen to the oxygenator. A method of perfusing an organ or tissue includes producing oxygen from a device such as an oxygen concentrator and an oxygen generator; supplying the produced oxygen, preferably as the oxygen is produced, to a perfusate to oxygenate the perfusate; and perfusing the organ or tissue with the oxygenated perfusate. The produced oxygen preferably has a concentration greater than the oxygen concentration in air.
摘要翻译：用于灌注器官或组织的装置包括用于灌注器官或组织的灌注回路; 用于氧化灌注液的氧合器，其通过灌注回路循环; 以及氧气供应装置，例如氧气浓缩器或氧气发生器，其被配置为向氧合器供应氧气。灌注器官或组织的方法包括从诸如氧气浓缩器和氧气发生器的装置产生氧气; 将产生的氧优选作为产生氧气供应给灌注液以使灌注液充氧; 并用含氧灌注液灌注器官或组织。所产生的氧优选具有大于空气中的氧浓度的浓度。

2. 外观设计

USD672466S1 Organ transporter 有权
标题翻译：器官运输
公开(公告)号：USD672466S1
公开(公告)日：2012-12-11
申请号：US29390871
申请日：2011-04-29
申请人： David Kravitz , Aaron Randall Ferber , Ross Lockwood , Rodney Hal Monson , Evan David Shapiro
设计人： David Kravitz , Aaron Randall Ferber , Ross Lockwood , Rodney Hal Monson , Evan David Shapiro

3. 发明申请

US20120277687A1 LIVING DONOR CANNULA 有权
标题翻译：生命捐助者
公开(公告)号：US20120277687A1
公开(公告)日：2012-11-01
申请号：US13097789
申请日：2011-04-29
申请人： David Kravitz , Christopher Steinman , David Pettinato
发明人： David Kravitz , Christopher Steinman , David Pettinato
IPC分类号： A61M5/00
CPC分类号： A61M39/0247 , A61M1/1008 , A61M39/28 , A61M39/284
摘要： Disclosed is a cannula including a first circumferential portion, a second circumferential portion, and a seal with a first clamping surface. The first circumferential portion and the second circumferential portion are configured to mutually cooperate to support a circumference of vasculature, and form a second clamping surface. The first clamping surface and the second clamping surface are configured to cooperate to secure an end of the vasculature.
摘要翻译：公开了一种套管，其包括第一周向部分，第二周向部分和具有第一夹紧表面的密封件。第一周向部分和第二周向部分被构造成相互配合以支撑脉管的周边，并且形成第二夹紧表面。第一夹紧表面和第二夹紧表面被配置成协作以固定脉管系统的端部。

4. 发明申请

US20080155372A1 Methods and apparatus for improving error indication performance in systems with low-density parity check codes 审中-公开
标题翻译：用于提高具有低密度奇偶校验码的系统中的误差指示性能的方法和装置
公开(公告)号：US20080155372A1
公开(公告)日：2008-06-26
申请号：US11642885
申请日：2006-12-21
申请人： David Kravitz , Samuel J. MacMullan , Andrew Thangaraj , Jianhan Liu
发明人： David Kravitz , Samuel J. MacMullan , Andrew Thangaraj , Jianhan Liu
IPC分类号： H03M13/05 , G06F11/10
CPC分类号： H03M13/1105 , H03M13/09 , H03M13/3738 , H03M13/3776 , H04L1/0045 , H04L1/0061 , H04L1/20
摘要： The present invention is directed to methods and apparatus for improving error indication performance in systems employing low-density parity check (LDPC) codes. In one aspect, a method and apparatus for providing error indication based on full LDPC parity check re-encoding are provided. In an embodiment, an LDPC encoder is employed at the receiver to re-encode the parity bits. In another embodiment, the parity bits are re-encoded recursively based on information readily available at the decoder of the receiver. In another aspect, a method and apparatus for providing error indication based on partial LDPC parity check re-encoding are provided. In an embodiment, partial checksum information is determined based on the decoder output and used to provide error indication. In a further aspect, a hybrid CRC checking and LDPC parity check re-encoding approach is provided. This approach further enhances error indication performance by reducing the miss probability compared to pure LDPC parity check re-encoding.
摘要翻译：本发明涉及用于改善使用低密度奇偶校验（LDPC）码的系统中的错误指示性能的方法和装置。一方面，提供了一种基于全LDPC奇偶校验重新编码提供错误指示的方法和装置。在一个实施例中，在接收机处采用LDPC编码器来重新编码奇偶校验位。在另一个实施例中，基于在接收机的解码器处容易获得的信息，奇偶校验比特被递归地重新编码。在另一方面，提供了一种用于基于部分LDPC奇偶校验重新编码提供错误指示的方法和装置。在一个实施例中，基于解码器输出确定部分校验和信息，并用于提供错误指示。另一方面，提供了混合CRC校验和LDPC奇偶校验重新编码方法。与纯LDPC奇偶校验重新编码相比，该方法通过减少丢失概率进一步增强了错误指示性能。

5. 发明申请

US20070180538A1 METHOD AND APPARATUS FOR LIMITING THE ABILITY OF A USER DEVICE TO REPLAY CONTENT 审中-公开
标题翻译：限制用户设备复制内容的能力的方法和装置
公开(公告)号：US20070180538A1
公开(公告)日：2007-08-02
申请号：US11531871
申请日：2006-09-14
申请人： David Kravitz , Sivakumar Muthuswamy , Steve Scherer
发明人： David Kravitz , Sivakumar Muthuswamy , Steve Scherer
IPC分类号： G06F17/30
CPC分类号： G06F21/10 , G06F2221/0711 , H04N5/913 , H04N21/2541 , H04N21/4181 , H04N21/4623 , H04N21/835 , H04N2005/91364
摘要： A method and an apparatus are provided for use in a user device for limiting the ability of the terminal of the user device to replay protected content. The low-level key that is used by the decryption component of the terminal to decrypt content is transient in that it expires if at least one predetermined expiration criteria is met. After they key has expired, it is no longer valid and thus cannot be used by the decryption component to decrypt protected content. Limiting the ability of the terminal to replay protected content is preferably accomplished in a way that does not affect the ability of the terminal to play and replay unprotected content.
摘要翻译：提供一种在用户设备中使用的方法和装置，用于限制用户设备的终端重放受保护内容的能力。由终端的解密组件用于解密内容的低级密钥是暂时性的，因为如果满足至少一个预定的到期标准，则它将过期。在密钥已过期之后，它不再有效，因此解密组件不能使用它来解密受保护的内容。限制终端重放受保护内容的能力优选以不影响终端播放和重放未受保护内容的能力的方式来实现。

6. 发明授权

US11490615B2 Assessing, maintaining and/or restoring viability of organs/tissues 有权
公开(公告)号：US11490615B2
公开(公告)日：2022-11-08
申请号：US13490852
申请日：2012-06-07
申请人： David Kravitz , Kelvin G. M. Brockbank , Lia H. Campbell
发明人： David Kravitz , Kelvin G. M. Brockbank , Lia H. Campbell
IPC分类号： A01N1/02
摘要： Methods for ex vivo perfusion of organs (and/or tissues) with a perfusate designed to condition the organ with the desired effect being that upon transplant, said organ, having been administered said perfusate, is less likely to experience delayed graft function, deleterious effects of ischemia/reperfusion injury, including inflammatory reactions, and/or other detrimental responses that can injure the organ or recipient including precipitating or enhancing an immunological reaction from the recipient with the potential of compromising the graft's and/or recipients short teen and/or long term health and proper functionality while monitoring, sustaining and/or restoring the viability of the organ and preserving the organ for storage and/or transport.

7. 发明授权

US10176887B1 Ex vivo methods for drug discovery, development and testing 有权
公开(公告)号：US10176887B1
公开(公告)日：2019-01-08
申请号：US11598800
申请日：2006-11-14
申请人： John Brassil , Christopher G. Curtis , David Kravitz
发明人： John Brassil , Christopher G. Curtis , David Kravitz
IPC分类号： G16H10/20
摘要： Methods for assaying properties in tissues or organs of drugs and other chemical compounds and substances include ex vivo normothermic perfusion with a fluid containing a test substance to obtain data regarding the tissue or organ, the substance and/or an interaction of the substance and the tissue or organ. The data can be used as, for example, part of a submission to a government regulatory organization.

8. 发明授权

US09022978B2 Universal sealring cannula 有权
标题翻译：通用密封插管
公开(公告)号：US09022978B2
公开(公告)日：2015-05-05
申请号：US13097789
申请日：2011-04-29
申请人： David Kravitz , Christopher Steinman , David Pettinato
发明人： David Kravitz , Christopher Steinman , David Pettinato
IPC分类号： A61M29/00 , A61M39/02 , A61M1/10 , A61M39/28
CPC分类号： A61M39/0247 , A61M1/1008 , A61M39/28 , A61M39/284
摘要： Disclosed is a cannula including a first circumferential portion, a second circumferential portion, and a seal with a first clamping surface. The first circumferential portion and the second circumferential portion are configured to mutually cooperate to support a circumference of vasculature, and form a second clamping surface. The first clamping surface and the second clamping surface are configured to cooperate to secure an end of the vasculature.
摘要翻译：公开了一种套管，其包括第一周向部分，第二周向部分和具有第一夹紧表面的密封件。第一周向部分和第二周向部分被构造成相互配合以支撑脉管的周边，并且形成第二夹紧表面。第一夹紧表面和第二夹紧表面被配置成协作以固定脉管系统的端部。

9. 发明授权

US08771930B2 Ex vivo methods for testing toxicity of substances using donated human organs or tissues 有权
标题翻译：使用捐赠的人体器官或组织测试物质毒性的离体方法
公开(公告)号：US08771930B2
公开(公告)日：2014-07-08
申请号：US11802059
申请日：2007-05-18
申请人： Gerald Curtis , John Brassil , David Kravitz
发明人： Gerald Curtis , John Brassil , David Kravitz
IPC分类号： A01N1/00
CPC分类号： G01N33/5082 , G01N33/5014 , G01N33/566 , G01N33/574 , G01N33/68 , G06Q20/102
摘要： Properties such as toxicity of substances may be determined by assaying properties, fates and effects of substances in an ex vivo metabolically active human organ or tissue under normothermic perfusion with a fluid containing a test substance. The data can be used as, for example, part of a submission to a government regulatory organization. Preferred methods use perfused endocrine gland organs or tissues to evaluate hormone or other bodily chemical disruption caused by substances and pre-donation diseased or injured organs or tissues.
摘要翻译：诸如物质的毒性的物质可以通过使用含有测试物质的流体在正常温度灌注下测定离体代谢活性人器官或组织中物质的性质，命运和作用来确定。数据可以用作例如向政府监管机构提交的一部分。优选的方法使用灌注的内分泌腺器官或组织来评估由物质和预先捐赠的患病或受伤的器官或组织引起的激素或其他身体化学物质的破坏。

10. 发明申请

US20140017657A1 ORGAN TRANSPORT APPARATUS WITH SAMPLE COMPARTMENTS 有权
标题翻译：机关运输装置
公开(公告)号：US20140017657A1
公开(公告)日：2014-01-16
申请号：US13545210
申请日：2012-07-10
申请人： David KRAVITZ , Christopher P. STEINMAN , David PETTINATO , Matthew COPITHORNE , Brian L. OTTS , Robert J. ALLEN , Frank P. NANNA , Peter DEMUYLDER
发明人： David KRAVITZ , Christopher P. STEINMAN , David PETTINATO , Matthew COPITHORNE , Brian L. OTTS , Robert J. ALLEN , Frank P. NANNA , Peter DEMUYLDER
IPC分类号： A01N1/02
CPC分类号： A01N1/0252 , A01N1/0247 , A01N1/0273
摘要： An apparatus for at least one of storage, treatment, assessment and transport of an organ or tissue includes a coolant container configured to cool the organ or tissue, a perfusion circuit configured to perfuse the organ or tissue, and a sample compartment for holding a biological sample. Preferred apparatus has a first internal compartment under a first cover (lid) of the apparatus that includes the coolant container and the sample compartment. The apparatus can include a second internal compartment under a second cover (lid) of the apparatus, the second internal compartment including at least part of the perfusion circuit and a sample compartment.
摘要翻译：用于器官或组织的储存，处理，评估和运输中的至少一个的装置包括构造成冷却器官或组织的冷却剂容器，构造成灌注器官或组织的灌注回路，以及用于保持生物样品。优选的装置在装置的第一盖（盖）下方具有包括冷却剂容器和样品室的第一内部隔室。该装置可以包括设备的第二盖（盖）下的第二内部隔室，第二内部隔室包括至少部分灌注回路和样品室。

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