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1. 发明申请

US20230125019A1 ADVANCED HUB APPARATUS FOR MOBILE COMPUTER 有权
公开(公告)号：US20230125019A1
公开(公告)日：2023-04-20
申请号：US17505541
申请日：2021-10-19
申请人： Kien Hoe Daniel Chin
发明人： Kien Hoe Daniel Chin
IPC分类号： G06F1/16
摘要： A port extension apparatus for extending ports of an end-user device comprising: a connecting port module for connecting to an end-user device, the connecting port module having first and second port units; a first video port module operatively connecting to the first port unit; a data transmission control module operatively connecting to the second port unit via a first data transmission port of the data transmission control module; a second video port module operatively connecting to a second data transmission port of the data transmission control module; and a data port module operatively connecting to a third data transmission port of the data transmission control module; wherein when a to-be-connected device connects to the first video port module, the first video port module and the connecting port module form a transmission path enabling video data transmission between the to-be-connected device and the end-user device; when a to-be-connected device connects to the second video port module, the data transmission control module controls video data transmission between the to-be-connected device and the end-user device; and when a to-be-connected device connects to the data port module, the data transmission control module controls data transmission between the to-be-connected device and the end-user device.

2. 外观设计

USD855616S1 Thunderbolt 3.0 USB-C connector 有权
公开(公告)号：USD855616S1
公开(公告)日：2019-08-06
申请号：US29585509
申请日：2016-11-24
申请人： Kien Hoe Daniel Chin
设计人： Kien Hoe Daniel Chin
摘要： FIG. 1 is a perspective view of a thunderbolt 3.0 USB-C connector;
FIG. 2 is a front view thereof;
FIG. 3 is a side view thereof;
FIG. 4 is a back side view thereof;
FIG. 5 is a side view thereof;
FIG. 6 is a side view thereof; and,
FIG. 7 is a side view thereof.
The broken lines are included to show environmental structure and form no part of the claimed design.

3. 发明申请

US20070025997A1 Use of biomolecular targets in the treatment and visualization of brain tumors 审中-公开
标题翻译：在脑肿瘤的治疗和可视化中使用生物分子靶标
公开(公告)号：US20070025997A1
公开(公告)日：2007-02-01
申请号：US11413566
申请日：2006-04-27
申请人： Usha Nagavarapu , David Shivak , Daniel Chin , Erik Foehr , Mirella Gonzalez-Zulueta
发明人： Usha Nagavarapu , David Shivak , Daniel Chin , Erik Foehr , Mirella Gonzalez-Zulueta
IPC分类号： A61K39/395 , C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6886 , A61K2039/505 , C07K16/2851 , C12Q2600/112 , C12Q2600/136 , C12Q2600/158 , G01N33/57407
摘要： The present invention relates to the use of proteins that are differentially expressed in primary brain tumor tissues, as compared to normal brain tissues, as biomolecular targets for brain tumor treatment therapies. Specifically, the present invention relates to the use of therapeutic and imaging agents, which specifically bind to one or more of the identified brain tumor protein targets. The present invention also provides compounds and pharmaceutically acceptable compositions for administration in the methods of the invention. Nucleic acid probes specific for the spliced mRNA encoding these variants and affinity reagents specific for the novel proteins are also provided.
摘要翻译：本发明涉及与正常脑组织相比，在原发性脑肿瘤组织中差异表达的蛋白质作为脑肿瘤治疗疗法的生物分子靶标的用途。具体地，本发明涉及特异性结合一种或多种所鉴定的脑肿瘤蛋白靶标的治疗和显像剂的用途。本发明还提供了用于本发明方法中给药的化合物和药学上可接受的组合物。还提供了针对编码这些变体的剪接mRNA特异性的核酸探针和对新蛋白特异的亲和试剂。

4. 发明申请

US20050260132A1 Monoclonal antibodies directed to receptor protein tyrosine phosphatase zeta 审中-公开
标题翻译：针对受体蛋白酪氨酸磷酸酶ζ的单克隆抗体
公开(公告)号：US20050260132A1
公开(公告)日：2005-11-24
申请号：US11097728
申请日：2005-03-31
申请人： Daniel Chin , Erik Foehr , Sabine Mueller , Thorsten Melcher
发明人： Daniel Chin , Erik Foehr , Sabine Mueller , Thorsten Melcher
IPC分类号： A61K39/395 , A61K47/48 , A61K51/00 , C07K16/28 , C07K16/30
CPC分类号： C07K16/3023 , A61K47/6819 , A61K47/6849 , A61K47/6855 , A61K47/6857 , A61K47/6861 , A61K47/6865 , A61K2039/505 , C07K16/28 , C07K16/3015 , C07K16/3038 , C07K16/3053 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92
摘要： The present invention relates to a method of inhibiting growth of tumor cells which overexpress a receptor protein tyrosine phosphatase zeta (PTPζ) by treatment of the cells with antibodies which recognize PTPζ and/or inhibit PTPζ function. The present invention also provides compounds and pharmaceutically acceptable compositions for administration in the methods of the invention. The present invention also provides novel splice variants of protein PTPζ, PTPζ SM1 and PTPζ SM2. Nucleic acid probes specific for the spliced mRNA encoding these variants and affinity reagents specific for the novel proteins are also provided.
摘要翻译：本发明涉及通过用识别PTPzeta和/或抑制PTPzeta功能的抗体处理细胞来抑制过表达受体蛋白酪氨酸磷酸酶ζ（PTPzeta）的肿瘤细胞生长的方法。本发明还提供了用于本发明方法中给药的化合物和药学上可接受的组合物。本发明还提供蛋白质PTPzeta，PTPzeta SM1和PTPzeta SM2的新型剪接变体。还提供了针对编码这些变体的剪接mRNA特异性的核酸探针和对新蛋白特异的亲和试剂。

5. 发明授权

US06841351B2 High-throughput transcriptome and functional validation analysis 失效
标题翻译：高通量转录组和功能验证分析
公开(公告)号：US06841351B2
公开(公告)日：2005-01-11
申请号：US10027807
申请日：2001-10-19
申请人： Li Gan , Mirella Gonzalez-Zulueta , Kristin Anton , Richa Wilson , Thorsten Melcher , Daniel Chin
发明人： Li Gan , Mirella Gonzalez-Zulueta , Kristin Anton , Richa Wilson , Thorsten Melcher , Daniel Chin
IPC分类号： C12N15/10 , C12Q1/68 , C07H21/04 , C12P19/34 , G01N33/566
CPC分类号： C12N15/1086
摘要： Methods for correlating genes and gene function are provided. Such methods generally involve selecting a candidate gene that appears to be correlated with a particular cellular state or activity and then validating the role of the candidate gene in establishment of such a cellular state or activity. Certain methods utilized RNA interference techniques in the validation process.
摘要翻译：提供了相关基因和基因功能的方法。这样的方法通常包括选择似乎与特定细胞状态或活性相关的候选基因，然后验证候选基因在建立这种细胞状态或活性中的作用。某些方法在验证过程中使用RNA干扰技术。

6. 发明授权

US06361416B1 Apparatus and methods for recovering abrasive from an abrasive-laden fluid for use with abrasive jet cutting systems 有权
标题翻译：用于从研磨剂的流体中回收磨料以用于磨料射流切割系统的装置和方法
公开(公告)号：US06361416B1
公开(公告)日：2002-03-26
申请号：US09383044
申请日：1999-08-25
申请人： Jordan J. Hopkins , Jonathan M. Stewart , Felice M. Sciulli , Katherine Zaring , Daniel Chin , John Massenburg , Daniel Devine
发明人： Jordan J. Hopkins , Jonathan M. Stewart , Felice M. Sciulli , Katherine Zaring , Daniel Chin , John Massenburg , Daniel Devine
IPC分类号： B24C900
CPC分类号： B26F3/008 , B24C1/045 , B24C9/003 , B24C9/006 , Y02P70/179
摘要： This invention relates to methods and apparatus for recovering abrasive for use with abrasive jet cutting systems. In one embodiment, an apparatus in accordance with the invention includes an abrasive-laden fluid handling device coupled to a catcher tank of an abrasive jet cutting system, a pre-classifier fluidly coupled to the abrasive-laden fluid handling device, a hydro-classifier fluidly coupled to the pre-classifier, a fine-particle separation tank fluidly coupled to a clarified-fluid flow outlet of the hydro-classifier, a wet abrasive receptacle positioned to receive a wet recovered abrasive discharged from the hydro-classifier, a de-watering device engageable with the wet recovered abrasive in wet abrasive receptacle, and a dryer unit. The abrasive-laden fluid handling device may include an abrasive-laden fluid conduit having a first end in fluid communication with the catcher tank and an abrasive-laden fluid outlet. Alternately, the abrasive-laden fluid handling device may include a fluid drive system. In another embodiment, a de-watering device includes a housing having a wet abrasive intake and a de-watered abrasive, and an eductor port situated along an abrasive travel path extending between the wet abrasive intake and the de-watered abrasive outlet, an eductor inlet coupled to the eductor port and coupleable to a source of eduction air, and a transport device. In a further embodiment, an apparatus includes an airflow control valve fluidly coupled to the eductor port and positionable in a first position to draw an entrained airflow from within the housing through the eductor port, and a second position to backflow the eduction air through the eductor port into the housing.
摘要翻译：本发明涉及用于回收用于磨料射流切割系统的磨料的方法和设备。在一个实施例中，根据本发明的装置包括耦合到磨料喷射切割系统的捕集罐的磨料载流体处理装置，流体耦合到磨料载流体处理装置的预分级器，加氢分级器流体耦合到预分类器，流体耦合到加氢分选机的澄清流体流出口的细颗粒分离罐，设置成接收从加氢分级器排出的湿回收磨料的湿磨料容器，可在湿磨机容器中与湿回收的磨料接合的浇水装置和干燥器单元。含磨料的流体处理装置可以包括具有磨料的流体导管，其具有与捕集罐和磨料填充的流体出口流体连通的第一端。或者，含磨料的流体处理装置可以包括流体驱动系统。在另一个实施例中，脱水装置包括具有湿磨料入口和脱水磨料的壳体，以及沿着在湿磨料入口和脱水磨料出口之间延伸的研磨行进路径设置的喷射器端口，喷射器入口连接到喷射器端口并且可耦合到排出的空气源，以及输送装置。在另一实施例中，一种装置包括流体耦合到喷射器端口的气流控制阀，并且可定位在第一位置，以便通过喷射器端口从壳体内抽出夹带的气流，以及第二位置，以使排出的空气通过喷射器港口进入住房。

7. 外观设计

USD891433S1 USB adapter apparatus 有权
公开(公告)号：USD891433S1
公开(公告)日：2020-07-28
申请号：US29710505
申请日：2019-10-23
申请人： Kien Hoe Daniel Chin
设计人： Kien Hoe Daniel Chin
摘要： FIG. 1 is a perspective view of an USB adapter apparatus;
FIG. 2 is a side view thereof;
FIG. 3 is a side view thereof;
FIG. 4 is a front view thereof;
FIG. 5 is a back view thereof;
FIG. 6 is a top view thereof;
FIG. 7 is a partially exploded view thereof;
FIG. 8 is a partially exploded view thereof;
FIG. 9 is a partially exploded view thereof;
FIG. 10 is a perspective view thereof, shown with an attached environmental cable;
FIG. 11 is a partially exploded view thereof, shown with a detached environmental cable; and,
FIG. 12 is a partially exploded view thereof, shown with a detached environmental cable.
The broken lines in FIGS. 10, 11, and 12 showing the additional cable depict environmental structure only and form no part of the claim, while all other broke lines depict portions of the USB adapter apparatus that form no part of the claimed design.

8. 发明授权

US06328638B1 Apparatus and methods for recovering abrasive from an abrasive-laden fluid 失效
标题翻译：从磨料载液中回收磨料的装置和方法
公开(公告)号：US06328638B1
公开(公告)日：2001-12-11
申请号：US09491684
申请日：2000-01-26
申请人： Jordan J. Hopkins , Jonathan M. Stewart , Felice M. Sciulli , Katherine Zaring , Daniel Chin , John Massenburg , Daniel Devine
发明人： Jordan J. Hopkins , Jonathan M. Stewart , Felice M. Sciulli , Katherine Zaring , Daniel Chin , John Massenburg , Daniel Devine
IPC分类号： B24B900
CPC分类号： B01D21/2416 , B01D21/0039 , B01D21/0045 , B01D21/0063 , B01D21/009 , B01D21/2494 , B24C1/045 , B24C9/003 , B24C9/006 , B26F3/008 , Y02P70/179
摘要： An improved apparatus and methods for recovering abrasive from an abrasive-laden fluid are shown and described. An abrasive-laden fluid handling device is coupled to a catcher tank to collect abrasive-laden fluid and transport it to a hydro-classifier. Wet recovered abrasive is discharged from the hydro-classifier and transferred to a de-watering device. The de-watering device removes water from the abrasive by decanting fluid and via use of an air eduction system. De-watered abrasive is then ejected from the de-watering device to a dryer unit, to be further dried and processed for reuse.
摘要翻译：显示和描述了一种改进的从含磨料流体中回收磨料的设备和方法。装载磨料的流体处理装置联接到捕集罐以收集磨料载流体并将其输送到加氢分级器。湿回收的磨料从加氢分级机排出并转移到脱水装置。脱水装置通过倾析流体和通过使用空气排出系统从磨料中除去水分。然后将脱水的研磨剂从脱水装置喷射到干燥器单元，以进一步干燥和处理以便重新使用。

9. 外观设计

USD874462S1 USB adapter apparatus 有权
公开(公告)号：USD874462S1
公开(公告)日：2020-02-04
申请号：US29710504
申请日：2019-10-23
申请人： Kien Hoe Daniel Chin
设计人： Kien Hoe Daniel Chin
摘要： FIG. 1 is a perspective back view of an USB adapter apparatus;
FIG. 2 is a perspective front view thereof;
FIG. 3 is a partially exploded back view thereof; and,
FIG. 4 is a side view thereof.
The broken lines are included to show environmental structure and form no part of the claimed design. The drawings and descriptions represent the left side of the embodiment. The claim is also for a mirror image right side thereof.

10. 发明授权

US09088090B2 Universal purpose power adapter 有权
标题翻译：通用型电源适配器
公开(公告)号：US09088090B2
公开(公告)日：2015-07-21
申请号：US13417109
申请日：2012-03-09
申请人： Kien Hoe Daniel Chin , Gang Feng
发明人： Kien Hoe Daniel Chin , Gang Feng
IPC分类号： H01M10/46 , H01R12/51 , H01R4/48
CPC分类号： H01R12/515 , H01R4/4818 , Y10T29/49117 , Y10T307/74
摘要： A universal purpose power adapter has a first box and a second box, in which the first box includes a first socket, a first plug and first terminal blocks, and the second box further comprises a second plug and second terminal blocks. The second plug couples to the first socket and to the power output port at the same time; the first plug couples to the charging port of the backup battery. A backup battery can be connected to a digital product via the power adaptor. A selector circuit in each of the first and second boxes, and coupled, facilitates power routing through the connected boxes.
摘要翻译：通用电源适配器具有第一盒和第二盒，其中第一盒包括第一插座，第一插头和第一接线盒，第二盒还包括第二插头和第二接线盒。第二个插头同时耦合到第一个插座和电源输出端口; 第一个插头连接到备用电池的充电端口。备用电池可以通过电源适配器连接到数字产品。第一和第二盒中的每一个中的选择器电路并且耦合，便于通过所连接的盒的电力布线。

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