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1. 发明授权

US10602740B2 Organ perfusion apparatus with downstream flow control 有权
公开(公告)号：US10602740B2
公开(公告)日：2020-03-31
申请号：US13545281
申请日：2012-07-10
申请人： David Kravitz , Christopher P. Steinman , Jeffrey S. Louis , Matthew Copithorne , Brian L. Otts , Peter Demuylder
发明人： David Kravitz , Christopher P. Steinman , Jeffrey S. Louis , Matthew Copithorne , Brian L. Otts , Peter Demuylder
IPC分类号： A01N1/02
摘要： An organ perfusion apparatus may include at least two tubes connected to an organ or tissue. A method of perfusing an organ or tissue may include connecting a first end of each of the at least two tubes to an organ or tissue, applying a fluid motive force to a perfusion fluid in the two tubes to force the fluid through the two tubes into the organ or tissue, and perfusing the organ or tissue through the at least two tubes such that the fluid motive force, provided by, e.g., a pump, and backpressure generated by the organ or tissue, establishes a flow balance between the at least two tubes. The flow balance may be altered without altering the fluid motive force that is applied.

2. 发明授权

US09357767B2 Organ transporter 有权
标题翻译：器官运输
公开(公告)号：US09357767B2
公开(公告)日：2016-06-07
申请号：US13545321
申请日：2012-07-10
申请人： Christopher P. Steinman , Rick W. Walker , Kirk C. Palmerton , Jeffrey S. Louis , David Pettinato , Matthew Copithorne , Brian L Otts , Peter Demuylder , James Guarrera , Ben O. Arrington
发明人： Christopher P. Steinman , Rick W. Walker , Kirk C. Palmerton , Jeffrey S. Louis , David Pettinato , Matthew Copithorne , Brian L Otts , Peter Demuylder , James Guarrera , Ben O. Arrington
IPC分类号： A01N1/02
CPC分类号： A01N1/0247 , A01N1/0273
摘要： A perfusion apparatus includes a coolant container having a basin-receiving recess that is at least partly surrounded by an inner chamber; a basin that is shaped to fit within the basin-receiving recess of the coolant container; and a cradle that is shaped to accept an organ and fit within the basin. The basin-receiving recess of the coolant container, the basin and the cradle each have positioning elements that are oriented such that the cradle is keyed to fit within the basin and the basin is keyed to fit within the coolant container, each in a single predetermined orientation. The plurality of positioning elements on the basin may include a plurality of protrusions on an outer surface of the basin.
摘要翻译：灌注装置包括：冷却剂容器，其具有至少部分地被内腔包围的盆容纳凹部; 成形为容纳在冷却剂容器的盆接收凹部内的盆; 和一个成形为接受器官并装配在盆内的摇篮。冷却剂容器，盆和托架的盆容纳凹槽各自具有定位元件，其定位成使得支架被键合以配合在盆内，并且盆被键合以装配在冷却剂容器内，每个以单个预定的方向。盆上的多个定位元件可以包括在盆的外表面上的多个突起。

4. 外观设计

USD692576S1 Drape for organ or tissue transporter 有权
标题翻译：用于器官或组织运输的悬垂
公开(公告)号：USD692576S1
公开(公告)日：2013-10-29
申请号：US29426749
申请日：2012-07-10
申请人： Christopher P. Steinman , Jeffrey S. Louis , Matthew Copithorne , Brian L. Otts , Peter Demuylder
设计人： Christopher P. Steinman , Jeffrey S. Louis , Matthew Copithorne , Brian L. Otts , Peter Demuylder

5. 发明授权

US5409461A Catheter introducer assembly with needle shielding device 失效
标题翻译：导管插管器组件带针屏蔽装置
公开(公告)号：US5409461A
公开(公告)日：1995-04-25
申请号：US127722
申请日：1993-09-28
申请人： Christopher P. Steinman
发明人： Christopher P. Steinman
IPC分类号： A61M25/06 , A61M5/00
CPC分类号： A61M25/0637 , A61M25/0618 , Y10S128/917
摘要： A winged catheter introducer is disclosed. The catheter introducer has a catheter, a robe attached to the catheter and a winged intermediate member between the catheter and the robe. Within the catheter and the robe is a needle with a stylet attached to it. The stylet is attached to a hub which facilitates the pulling of the needle out of the catheter and through the robe. Attached to the robe is an adapter with a septum attached to it. The needle is provided with an opening extending from the needle wall to the needle lumen. A shielding device is provided which is attached to the adapter. The shielding device includes a needle container which is designed to trap the needle. A needle shield is provided inside the needle container. The needle is provided with an area of enlarged diameter. This area of enlarged diameter interacts with the needle shield when the needle is withdrawn from the catheter and robe and into the needle container. The needle shield is provided with an orifice through which the needle and stylet can fit but through which the area of enlarged diameter cannot pass. When the needle is withdrawn from the catheter and tube and into the needle container, it is trapped by the needle shield. The needle shield is also provided with a transverse wall which snaps over the point of the needle.
摘要翻译：公开了一种翼状导管导引器。导管导引器具有导管，连接到导管的长袍和导管和长袍之间的有翅的中间构件。在导管内，长袍是带有探针的针。探针连接到一个轮毂上，这样便于将针从导管拉出并穿过长袍。连接在长袍上的是带有隔垫的适配器。针设置有从针壁向针内腔延伸的开口。提供了一个连接到适配器的屏蔽装置。屏蔽装置包括针容器，该针容器被设计成捕获针。在针容器内设置针罩。针设置有直径增大的区域。当针从导管和长袍取出并进入针容器时，该扩大直径的区域与针罩相互作用。针罩设有一个孔，针和探针可以穿过该孔，但扩大直径的区域不能穿过该孔。当针从导管和管中取出并进入针容器时，它被针罩遮住。针护罩还设有横向壁，该横向壁在针的点上卡扣。

6. 发明授权

US5304136A Needle sheath 失效
标题翻译：针鞘
公开(公告)号：US5304136A
公开(公告)日：1994-04-19
申请号：US832241
申请日：1992-02-07
申请人： Timothy J. Erskine , Christopher P. Steinman
发明人： Timothy J. Erskine , Christopher P. Steinman
IPC分类号： A61M39/00 , A61M5/32 , A61M25/00 , A61M25/06 , A61M5/00
CPC分类号： A61M25/0631 , A61M2005/3249
摘要： A needle shielding device in which, after use, a needle is confined in a chamber having a first hole through which the needle can enter the chamber. The needle is drawn into the chamber through the hole. The chamber is made up of telescopic members. The needle strikes the rear wall of the chamber causing the telescopic members to telescope apart. Once in the chamber, the needle will not readily escape through the first hole.
摘要翻译：一种针屏蔽装置，其中在使用后将针限制在具有针可以穿过该腔室的第一孔的腔室中。针通过孔被吸入腔室。该室由伸缩构件组成。针撞击室的后壁，导致伸缩构件望远镜分离。一旦进入腔室，针头就不会通过第一个孔容易地逃逸。

7. 发明授权

US08814889B2 Cannula with floating clamp member 有权
标题翻译：插管与浮动夹具
公开(公告)号：US08814889B2
公开(公告)日：2014-08-26
申请号：US13545185
申请日：2012-07-10
申请人： Christopher P. Steinman , Jason A. Belton , Kirk C. Palmerton , Karl H. Beitzel , Rick W. Walker , Matthew Copithorne , Brian Otts , James V. Guarrera
发明人： Christopher P. Steinman , Jason A. Belton , Kirk C. Palmerton , Karl H. Beitzel , Rick W. Walker , Matthew Copithorne , Brian Otts , James V. Guarrera
IPC分类号： A61B17/08
CPC分类号： A01N1/0247 , A61B17/122 , A61B17/28 , A61B2017/00907 , A61B2017/00969 , A61B2017/2808
摘要： A cannula has a longitudinal base member having a first clamping end and a longitudinal arm member pivotally attached to the longitudinal base member and having a second clamping end, the cannula being in a closed position when the first and second clamping ends are brought together. A first clamp member is located at the first clamping end and has a first passage. A second clamp member is rotatably attached to the arm member at the second clamping end and has a second passage. The first and second passages form a combined passage when the clamp is in the closed position. The cannula may have a first locking member positioned on the arm member and a second locking member positioned on the base member. The first and second locking members interact with each other to lock the cannula in the closed position.
摘要翻译：套管具有纵向底座构件，该纵向底座构件具有第一夹紧端和纵向臂构件，所述纵向臂构件可枢转地附接到纵向底座构件并且具有第二夹紧端，当第一和第二夹紧端部接合在一起时，套管处于关闭位置。第一夹紧构件位于第一夹紧端并且具有第一通道。第二夹紧构件在第二夹持端处可旋转地附接到臂构件并具有第二通道。当夹具处于关闭位置时，第一和第二通道形成组合的通道。套管可以具有定位在臂构件上的第一锁定构件和定位在基座构件上的第二锁定构件。第一和第二锁定构件相互作用以将套管锁定在关闭位置。

8. 发明申请

US20140017666A1 FILTRATION IN ORGAN PERFUSION APPARATUS 审中-公开
标题翻译：有机香水装置过滤
公开(公告)号：US20140017666A1
公开(公告)日：2014-01-16
申请号：US13545598
申请日：2012-07-10
申请人： Christopher P STEINMAN , Jeffrey S LOUIS
发明人： Christopher P STEINMAN , Jeffrey S LOUIS
IPC分类号： A01N1/02 , B29C45/14
CPC分类号： A01N1/0247
摘要： A filter for filtering perfusate is integrated with an exterior portion of an organ container. The filter may be used in an apparatus for perfusing an organ. The perfusion apparatus may include an organ container configured to contain an organ, the filter integrated with an exterior portion of the organ container, and another filter. At least the filter integrated with an exterior portion of the organ container may be provided in a sterilized disposable kit.
摘要翻译：用于过滤灌洗液的过滤器与器官容器的外部部分结合。过滤器可用于灌注器官的装置中。灌注装置可以包括构造成容纳器官的器官容器，与器官容器的外部整合的过滤器和另一过滤器。至少与器官容器的外部整合的过滤器可以设置在灭菌的一次性套件中。

9. 发明申请

US20140017665A1 ORGAN TRANSPORTER WITH OXYGEN GENERATION 审中-公开
标题翻译：具有氧气生成的有机运输机
公开(公告)号：US20140017665A1
公开(公告)日：2014-01-16
申请号：US13545514
申请日：2012-07-10
申请人： Christopher P. STEINMAN , David KRAVITZ , Aaron R. FERBER , Ross LOCKWOOD , Rodney H. MONSON , Evan D. SHAPIRO
发明人： Christopher P. STEINMAN , David KRAVITZ , Aaron R. FERBER , Ross LOCKWOOD , Rodney H. MONSON , Evan D. SHAPIRO
IPC分类号： A01N1/02
CPC分类号： A01N1/0247
摘要： An apparatus for perfusing an organ or tissue includes a perfusion circuit for perfusing the organ or tissue; an oxygenator for oxygenating perfusate that circulates through the perfusion circuit; and an oxygen supply device such as an oxygen concentrator or an oxygen generator configured to supply oxygen to the oxygenator. A method of perfusing an organ or tissue includes producing oxygen from a device such as an oxygen concentrator and an oxygen generator; supplying the produced oxygen, preferably as the oxygen is produced, to a perfusate to oxygenate the perfusate; and perfusing the organ or tissue with the oxygenated perfusate. The produced oxygen preferably has a concentration greater than the oxygen concentration in air.
摘要翻译：用于灌注器官或组织的装置包括用于灌注器官或组织的灌注回路; 用于氧化灌注液的氧合器，其通过灌注回路循环; 以及氧气供应装置，例如氧气浓缩器或氧气发生器，其被配置为向氧合器供应氧气。灌注器官或组织的方法包括从诸如氧气浓缩器和氧气发生器的装置产生氧气; 将产生的氧优选作为产生氧气供应给灌注液以使灌注液充氧; 并用含氧灌注液灌注器官或组织。所产生的氧优选具有大于空气中的氧浓度的浓度。

10. 外观设计

USD693937S1 Tube frame 有权
标题翻译：管架
公开(公告)号：USD693937S1
公开(公告)日：2013-11-19
申请号：US29426699
申请日：2012-07-10
申请人： Christopher P. Steinman , Jeffrey S. Louis , David Pettinato , Matthew Copithorne , Brian L Otts , Peter Demuylder , James Guarrera
设计人： Christopher P. Steinman , Jeffrey S. Louis , David Pettinato , Matthew Copithorne , Brian L Otts , Peter Demuylder , James Guarrera

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