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1. 发明申请

US20210345634A1 DISSOLVING COFFEE BEADS 有权
公开(公告)号：US20210345634A1
公开(公告)日：2021-11-11
申请号：US17315245
申请日：2021-05-07
申请人： Christopher Burns
发明人： Christopher Burns
IPC分类号： A23F5/24 , A23F5/40 , A23F5/26 , B65D65/46 , B65D25/22 , B65D25/54 , B65D85/00 , B65D25/52
摘要： A coffee capsule dispensing assembly that includes at least one substantially gelatin casing capsule or composite which contains a coffee concentrate or composite or coffee enhancing substance. The gelatin casing capsule with a hydrolyzed collagen gelatin portion is designed to dissolve in an aqueous solution. A housing assembly with a distal end and a proximal end is designed to contain the at least one gelatin casing capsule. A depressible button assembly is disposed substantially at the proximal end of the housing assembly and is designed to advance the at least one gelatin casing capsule toward the distal end of the housing assembly. A latch and release assembly at the distal end of the housing assembly is designed to singularly release the at least one gelatin casing capsule when the at least one gelatin casing capsule is advanced by the depressible button assembly.

2. 发明授权

US09292831B2 Monitoring data elements across multiple networks and processes 有权
标题翻译：监控跨多个网络和进程的数据元素
公开(公告)号：US09292831B2
公开(公告)日：2016-03-22
申请号：US14049581
申请日：2013-10-09
申请人： Christopher Burns , John Woolley
发明人： Christopher Burns , John Woolley
IPC分类号： G06F15/173 , G06Q10/10
CPC分类号： G06Q10/10
摘要： The invention described here is a computer-related method for analyzing and reporting the current status of a wide array of processes and conditions across multiple networks and systems. It employs independent software entities called “Blades” to control the retrieval, analysis and characterization of each situation, combined with a common presentation system that displays those characterizations in a simple graphical vocabulary for expressing degrees of positive and negative significance. By employing Tiles or similar independent graphical reports, shown together on the screen of a desktop computer, notebook, tablet, mobile device or wearable interactive display, the invention described here allows the user to see his or her world at a glance.
摘要翻译：这里描述的发明是一种用于分析和报告跨多个网络和系统的广泛流程和状况的当前状态的计算机相关方法。它采用名为“刀片”的独立软件实体来控制每种情况的检索，分析和表征，并结合一个共同的演示系统，在简单的图形词汇表中显示这些表征，以表达正面和负面意义的程度。通过使用台式计算机，笔记本，平板电脑，移动设备或可穿戴互动显示器的屏幕上一起显示的瓷砖或类似的独立图形报告，这里描述的发明允许用户一目了然地看到他或她的世界。

3. 发明申请

US20070285508A1 STEREO IMAGING SYSTEM AND METHOD FOR USE IN TELEROBOTIC SYSTEMS 审中-公开
标题翻译：立体成像系统和用于电磁系统的方法
公开(公告)号：US20070285508A1
公开(公告)日：2007-12-13
申请号：US11843871
申请日：2007-08-23
申请人： DAVID GERE , Christopher Burns , John Stern , Michael Tierney
发明人： DAVID GERE , Christopher Burns , John Stern , Michael Tierney
IPC分类号： H04N15/00
CPC分类号： G02B23/2415 , A61B1/00183 , A61B1/00193 , H04N13/10 , H04N13/239 , H04N13/246 , H04N13/296 , H04N13/327 , H04N2005/2255
摘要： This invention relates to a stereo imaging system for use in telerobotic systems. A method of imaging a target site in a stereo imaging system is provided. The method typically includes capturing a right and a left optical image of the target site and transforming the right and the left optical images preferably into digital information. The method further includes converting the digital information into opposed images of the target site displayed on a stereo display of the stereo imaging system, one of the opposed images being associated with the right optical image and the other of the opposed images being associated with the left optical image. The method further includes regulating the digital information to cause the positions of the target site displayed on the opposed images to change relative to each other. The invention further provides for a method of aligning the opposed images, to a method of adjusting the stereo working distance of an image capture device, such as an endoscope and to a stereo imaging system.
摘要翻译：本发明涉及一种用于远程遥控系统的立体成像系统。提供了一种在立体成像系统中成像目标部位的方法。该方法通常包括捕获目标站点的右光学图像和左光学图像，并将左右光学图像优选地变换为数字信息。该方法还包括将数字信息转换为立体成像系统的立体显示器上显示的目标站点的相对图像，相对图像中的一个与右光学图像相关联，另一个相对的图像与左侧光学图像。所述方法还包括调节所述数字信息以使所述相对图像上显示的所述目标站点的位置相对于彼此改变。本发明还提供了一种将相对图像对准的方法，一种调整诸如内窥镜和立体成像系统的图像捕获装置的立体声工作距离的方法。

4. 发明申请

US20070276607A1 Crystal structure and uses thereof 审中-公开
公开(公告)号：US20070276607A1
公开(公告)日：2007-11-29
申请号：US11649951
申请日：2007-01-04
申请人： Andrew Wilks , Christopher Burns , Emmanuelle Fantino , Isabelle Lucet , Jamie Rossjohn , Michelle Styles
发明人： Andrew Wilks , Christopher Burns , Emmanuelle Fantino , Isabelle Lucet , Jamie Rossjohn , Michelle Styles
IPC分类号： G06F19/00 , C12N9/12
CPC分类号： C12N9/1205 , C07K2299/00 , Y02A90/26
摘要： The present invention relates to X-ray crystallography studies of a JAK2 kinase domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.

5. 发明申请

US20070136006A1 Crystal structure and uses thereof 审中-公开
标题翻译：晶体结构及其用途
公开(公告)号：US20070136006A1
公开(公告)日：2007-06-14
申请号：US11650613
申请日：2007-01-04
申请人： Andrew Wilks , Christopher Burns , Emmanuelle Fantino , Isabelle Lucet , Jamie Rossjohn , Michelle Styles
发明人： Andrew Wilks , Christopher Burns , Emmanuelle Fantino , Isabelle Lucet , Jamie Rossjohn , Michelle Styles
IPC分类号： G06F19/00 , C12N9/12
CPC分类号： C12N9/1205 , C07K2299/00 , Y02A90/26
摘要： The present invention relates to X-ray crystallography studies of a JAK2 kinase domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
摘要翻译：本发明涉及JAK2激酶结构域的X射线晶体学研究。更具体地，涉及与抑制剂结合的JAK2激酶结构域的晶体结构。本发明还涉及晶体和相关结构信息用于选择和筛选与JAK2和相关蛋白相互作用的化合物以及可用于治疗由不适当的JAK2活性介导的疾病的化合物。

6. 发明申请

US20070129895A1 Crystal structure and uses thereof 审中-公开
公开(公告)号：US20070129895A1
公开(公告)日：2007-06-07
申请号：US11650062
申请日：2007-01-04
申请人： Andrew Wilks , Christopher Burns , Emmanuelle Fantino , Isabelle Lucet , Jamie Rossjohn , Michelle Styles
发明人： Andrew Wilks , Christopher Burns , Emmanuelle Fantino , Isabelle Lucet , Jamie Rossjohn , Michelle Styles
IPC分类号： G06F19/00
CPC分类号： C12N9/1205 , C07K2299/00 , Y02A90/26
摘要： The present invention relates to X-ray crystallography studies of a JAK2 kinase domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.

7. 发明申请

US20070128709A1 Crystal structure and uses thereof 有权
标题翻译：晶体结构及其用途
公开(公告)号：US20070128709A1
公开(公告)日：2007-06-07
申请号：US11248478
申请日：2005-10-11
申请人： Andrew Wilks , Christopher Burns , Emmanuelle Fantino , Isabelle Lucet , Jamie Rossjohn , Michelle Styles
发明人： Andrew Wilks , Christopher Burns , Emmanuelle Fantino , Isabelle Lucet , Jamie Rossjohn , Michelle Styles
IPC分类号： G06F19/00 , G01N31/00 , C12N9/12 , G06T15/00
CPC分类号： C07D491/04 , C07D471/04 , C07K2299/00 , C12N9/1205 , Y02A90/26
摘要： The present invention relates to X-ray crystallography studies of a human Janus Kinase 2 (JAK2) domain. More particularly, it relates to the crystal structure of a JAK2 kinase domain bound to an inhibitor. The invention further relates to the use of the crystal and related structural information to select and screen for compounds that interact with JAK2 and related proteins and to compounds that could be used for the treatment of diseases mediated by inappropriate JAK2 activity.
摘要翻译：本发明涉及人类Janus Kinase 2（JAK2）结构域的X射线晶体学研究。更具体地，涉及与抑制剂结合的JAK2激酶结构域的晶体结构。本发明还涉及晶体和相关结构信息用于选择和筛选与JAK2和相关蛋白相互作用的化合物以及可用于治疗由不适当的JAK2活性介导的疾病的化合物。

8. 发明申请

US20070099935A1 Azole-based kinase inhibitors 有权
标题翻译：基于唑类激酶抑制剂
公开(公告)号：US20070099935A1
公开(公告)日：2007-05-03
申请号：US10581412
申请日：2004-12-03
申请人： Christopher Burns , Andrew Wilks , Xianyong Bu
发明人： Christopher Burns , Andrew Wilks , Xianyong Bu
IPC分类号： A61K31/497 , C07D403/04 , C07D403/14
CPC分类号： C07D471/04 , C07D401/14 , C07D403/04 , C07D403/14
摘要： A compound of general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof is described. A method of treating kinase-associated disease states using the compound of formula (I) is also described.
摘要翻译：描述了通式（I）的化合物或其药学上可接受的前药，盐，水合物，溶剂合物，结晶形式或非对映异构体。还描述了使用式（I）化合物治疗激酶相关疾病状态的方法。

9. 发明申请

US20070060619A1 Nicotinamide-based kinase inhibitors 有权
标题翻译：基于烟酰胺的激酶抑制剂
公开(公告)号：US20070060619A1
公开(公告)日：2007-03-15
申请号：US10537719
申请日：2003-12-15
申请人： Christopher Burns , Marcel Kling
发明人： Christopher Burns , Marcel Kling
IPC分类号： A61K31/4436 , A61K31/455 , A61K31/4433 , C07D409/02 , C07D405/02 , C07D213/46
CPC分类号： C07D213/82 , C07D401/12 , C07D405/04 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/14
摘要： A compound of the general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof is described. A method of treating tyrosine kinase-associated disease states in a subject using a compound of formula (I) is also described.
摘要翻译：描述了通式（I）的化合物或其药学上可接受的前药，盐，水合物，溶剂合物，结晶形式或非对映异构体。还描述了使用式（I）化合物治疗受试者中酪氨酸激酶相关疾病状态的方法。

10. 发明申请

US20050288345A1 Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases 有权
标题翻译：用于治疗或预防肺病毒感染和相关疾病的化合物，组合物和方法
公开(公告)号：US20050288345A1
公开(公告)日：2005-12-29
申请号：US10524313
申请日：2003-08-11
申请人： David Rys , Theodore Nitz , Janet Gaboury , Christopher Burns , Daniel Pevear , Thomas Lessen , Torsten Herbertz
发明人： David Rys , Theodore Nitz , Janet Gaboury , Christopher Burns , Daniel Pevear , Thomas Lessen , Torsten Herbertz
IPC分类号： A61K31/41 , C07D257/04 , C07D43/02
CPC分类号： C07D257/04 , A61K31/41 , A61K38/21 , A61K39/395
摘要： Compounds, compositions and methods are provided for the prophylaxis and treatment of infections caused by viruses of the Pneumovirinae subfamily of Paramyxoviridae and diseases associated with such infections.
摘要翻译：提供了化合物，组合物和方法用于预防和治疗由副粘病毒肺炎链球菌亚科病毒引起的感染和与此类感染有关的疾病。

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