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1. 发明授权

US08436007B2 Inhibitors of protein kinases 失效
标题翻译：蛋白激酶抑制剂
公开(公告)号：US08436007B2
公开(公告)日：2013-05-07
申请号：US12451042
申请日：2008-04-24
申请人： Philipp Wabnitz , Heike Schauerte , Hans Allgeier , Martin Augustin , Lutz Zeitlmann , Michael A. Pleiss , Gabriele Stumm , Anke Mueller
发明人： Philipp Wabnitz , Heike Schauerte , Hans Allgeier , Martin Augustin , Lutz Zeitlmann , Michael A. Pleiss , Gabriele Stumm , Anke Mueller
IPC分类号： C07D239/42 , A61K31/505
CPC分类号： C07D239/42
摘要： The present invention relates to inhibitors of cyclin-dependent kinases and therapeutic applications thereof. Furthermore, the invention relates to methods of preventing and/or treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases comprising the administration of an effective amount of at least one inhibitor of cyclin-dependent kinases.
摘要翻译：本发明涉及细胞周期蛋白依赖性激酶的抑制剂及其治疗应用。此外，本发明涉及预防和/或治疗任何类型的疼痛，炎性疾病，免疫疾病，增殖性疾病，感染性疾病，心血管疾病和神经变性疾病的方法，包括施用有效量的至少一种细胞周期蛋白抑制剂，依赖性激酶。

2. 发明授权

US08507498B2 4, 6-disubstituted aminopyrimidine derivatives as inhibitors of protein kinases 失效
标题翻译： 4,6-二取代氨基嘧啶衍生物作为蛋白激酶的抑制剂
公开(公告)号：US08507498B2
公开(公告)日：2013-08-13
申请号：US12451039
申请日：2008-04-24
申请人： Philipp Wabnitz , Heike Schauerte , Hans Allgeier , Martin Augustin , Lutz Zeitlmann , Michael A. Pleiss , Gabriele Stumm , Anke Mueller , Axel Choidas , Bert Klebl , Gerhard Mueller , Wilfried Schwab , Joelle Le , Jackie Macritchie , Don Simpson
发明人： Philipp Wabnitz , Heike Schauerte , Hans Allgeier , Martin Augustin , Lutz Zeitlmann , Michael A. Pleiss , Gabriele Stumm , Anke Mueller , Axel Choidas , Bert Klebl , Gerhard Mueller , Wilfried Schwab , Joelle Le , Jackie Macritchie , Don Simpson
IPC分类号： A01N43/54 , C07D239/42 , C07D401/04
CPC分类号： C07D239/42 , C07D239/48 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12
摘要： The present invention relates to inhibitors of general Formula (I) of cyclin-dependent kinases and therapeutic applications thereof. Furthermore, the invention relates to compounds for preventing and/or treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases.
摘要翻译：本发明涉及细胞周期蛋白依赖性激酶的通式（I）的抑制剂及其治疗应用。此外，本发明涉及用于预防和/或治疗任何类型的疼痛，炎症性疾病，免疫疾病，增殖性疾病，感染性疾病，心血管疾病和神经变性疾病的化合物。

3. 发明申请

US20100184789A1 INHIBITORS OF PROTEIN KINASES 失效
标题翻译：蛋白激酶抑制剂
公开(公告)号：US20100184789A1
公开(公告)日：2010-07-22
申请号：US12451042
申请日：2008-04-24
申请人： Philipp Wabnitz , Heike Schauerte , Hans Allgeier , Martin Augustin , Lutz Zeitlmann , Michael A. Pleiss , Gabriele Stumm , Anke Mueller
发明人： Philipp Wabnitz , Heike Schauerte , Hans Allgeier , Martin Augustin , Lutz Zeitlmann , Michael A. Pleiss , Gabriele Stumm , Anke Mueller
IPC分类号： A61K31/505 , C07D239/42 , A61P37/00 , A61P9/00 , A61P25/28 , A61P29/00 , A61P31/00
CPC分类号： C07D239/42
摘要： The present invention relates to inhibitors of cyclin-dependent kinases and therapeutic applications thereof. Furthermore, the invention relates to methods of preventing and/or treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases comprising the administration of an effective amount of at least one inhibitor of cyclin-dependent kinases.
摘要翻译：本发明涉及细胞周期蛋白依赖性激酶的抑制剂及其治疗应用。此外，本发明涉及预防和/或治疗任何类型的疼痛，炎性疾病，免疫疾病，增殖性疾病，感染性疾病，心血管疾病和神经变性疾病的方法，包括施用有效量的至少一种细胞周期蛋白抑制剂，依赖性激酶。

4. 发明申请

US20110306602A1 4, 6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES 失效
标题翻译：作为蛋白激酶抑制剂的4,6-取代的氨基嘧啶衍生物
公开(公告)号：US20110306602A1
公开(公告)日：2011-12-15
申请号：US12451039
申请日：2008-04-24
申请人： Philipp Wabnitz , Heike Schauerte , Hans Allgeier , Lutz Zeitlmann , Anke Mueller , Martin Augustin , Michael A. Pleiss , Gabriele Stumm , Axel Choidas , Bert Klebl , Gerhard Mueller , Wilfried Schwab , Joelle Le , Jackie Macritchie , Don Simpson
发明人： Philipp Wabnitz , Heike Schauerte , Hans Allgeier , Lutz Zeitlmann , Anke Mueller , Martin Augustin , Michael A. Pleiss , Gabriele Stumm , Axel Choidas , Bert Klebl , Gerhard Mueller , Wilfried Schwab , Joelle Le , Jackie Macritchie , Don Simpson
IPC分类号： A61K31/55 , C07D405/12 , C07D409/12 , C07D401/12 , C07D413/12 , C07D403/12 , C07D417/12 , C07D401/10 , C07D413/10 , C07D403/10 , A61K31/505 , A61K31/5377 , A61K31/541 , A61K31/506 , A61P29/00 , A61P37/00 , A61P35/00 , A61P31/00 , A61P9/00 , A61P25/28 , C07D239/42
CPC分类号： C07D239/42 , C07D239/48 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12
摘要： The present invention relates to inhibitors of general Formula (I) of cyclin-dependent kinases and therapeutic applications thereof. Furthermore, the invention relates to compounds for preventing and/or treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases.
摘要翻译：本发明涉及细胞周期蛋白依赖性激酶的通式（I）的抑制剂及其治疗应用。此外，本发明涉及用于预防和/或治疗任何类型的疼痛，炎症性疾病，免疫疾病，增殖性疾病，感染性疾病，心血管疾病和神经变性疾病的化合物。

5. 发明授权

US07193005B2 Radiation-curable aqueous dispersions 有权
标题翻译：可辐射固化的水性分散体
公开(公告)号：US07193005B2
公开(公告)日：2007-03-20
申请号：US10512853
申请日：2003-05-21
申请人： Joerg Leuninger , Wolfgang Paulus , Anke Mueller
发明人： Joerg Leuninger , Wolfgang Paulus , Anke Mueller
IPC分类号： C08F8/00 , C08G18/42 , C08J3/00 , C08K3/20 , C08L47/00
CPC分类号： C08F285/00 , C08F257/02 , C08F265/00 , C08F291/00 , C09D151/003 , Y10T428/31855
摘要： Aqueous polymer dispersions comprising a) 50–70% by weight of polymer particles composed of at least two different (co)polymers having glass transition temperatures each above 50° C. and synthesized from at least 80% by weight of at least one principal monomer, 0.1–10% by weight of at least one auxiliary monomer, and 0–3% by weight of at least one crosslinker molecule, the difference in the glass transition temperatures (Tg) of the different polymers being at least 10° C., and b) 30–50% by weight of at least one polyfunctional (meth)acrylate, the dispersion a) being subjected to physical and/or chemical deodorization.
摘要翻译：含水聚合物分散体包含a）50-70％（重量）由至少两种不同（共）聚合物组成的聚合物颗粒，其玻璃化转变温度各自高于50℃，并由至少一种主要单体至少80％重量合成，0.1-10重量％的至少一种辅助单体和0-3重量％的至少一种交联剂分子，不同聚合物的玻璃化转变温度（T N）至少10℃，和b）30-50重量％的至少一种多官能（甲基）丙烯酸酯，所述分散体a）进行物理和/或化学除臭。

6. 发明申请

US20060231121A1 Low pressure injection module and method for low pressure injection cleaning with residual dirt analysis of components 审中-公开
标题翻译：低压注射模块和低压注射清洗方法，具有组分残留污物分析
公开(公告)号：US20060231121A1
公开(公告)日：2006-10-19
申请号：US10550052
申请日：2004-03-24
申请人： Konrad Koeberle , Anke Mueller
发明人： Konrad Koeberle , Anke Mueller
IPC分类号： B08B7/04 , B08B3/00
CPC分类号： B08B3/026 , B08B2203/0229
摘要： A method for low-pressure spray cleaning and residual contaminant analysis of components includes providing a receiver tank filled with flushing medium, pressurizing the receiver tank with compressed air on the inlet side, transmitting the pressurized flushing medium to a spray lance, spray cleaning a component by spraying the flushing medium from the spray lance, collecting the particle-containing flushing medium after the spray cleaning in a collection tank, providing an inline analysis filter positioned on an outflow side of the collection tank in such a way that particle-containing flushing medium flows through it, filtering the particles out of the flushing medium using the analysis filter, and finally analyzing the residual contamination filtered out by the analysis filter. A low-pressure spray module suitable for use with this method is also provided.
摘要翻译：用于低压喷雾清洗和部件残留污染物分析的方法包括提供一个填充有冲洗介质的接收罐，在入口侧用压缩空气对接收罐加压，将加压冲洗介质传送到喷枪，喷雾清洗组件通过从喷枪喷射冲洗介质，在收集罐中将喷雾清洁之后收集含有颗粒的冲洗介质，提供位于收集罐的流出侧上的在线分析过滤器，使得含有颗粒的冲洗介质流过其中，使用分析过滤器将颗粒从冲洗介质中过滤，最后分析由分析过滤器滤出的残留污染物。还提供了适用于该方法的低压喷雾模块。

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