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1. 发明授权

US4623410A Arrow master-straightener/conditioner 失效
标题翻译：箭头大师直发器/护发素
公开(公告)号：US4623410A
公开(公告)日：1986-11-18
申请号：US564395
申请日：1983-12-22
申请人： Axel P. Hillesheim , Andrew M. Bray
发明人： Axel P. Hillesheim , Andrew M. Bray
IPC分类号： F41B5/14 , G01B5/00 , C05B7/00
CPC分类号： F41B5/1446 , G01B5/0023
摘要： The invention disclosed teaches an arrow straightening machine which includes a nock or head alignment bearing attachment which allows for correction of any eccentricity or misaligmnent between the nock or head and the arrow shaft. The method discloses adhesively bonding the nock or head to the arrow shaft using the attachment device to align while the adhesive is in the unset condition.
摘要翻译：所公开的发明教导了一种箭头矫直机，其包括一个可以校正在nock或头部与箭头轴之间的任何偏心或偏差的nock或头部对准轴承附件。该方法公开了在粘合剂处于未设定状态的同时，使用附接装置将nock或头部粘合到箭头轴上以对准。

2. 发明授权

US6153618A Inhibitors of glycogen synthase 3 kinase 失效
标题翻译：糖原合成酶3激酶抑制剂
公开(公告)号：US6153618A
公开(公告)日：2000-11-28
申请号：US948887
申请日：1997-10-10
申请人： Peter Schultz , David B. Ring , Stephen D. Harrison , Andrew M. Bray
发明人： Peter Schultz , David B. Ring , Stephen D. Harrison , Andrew M. Bray
IPC分类号： C07D473/16 , A61K31/52
CPC分类号： C07D473/16
摘要： Compounds of formula 1: ##STR1## wherein R.sub.1 is alkyl, cycloalkyl, aryl, aralkyl, heteroaryl, or heteroaralkyl, substituted with 0-3 substituents selected from lower alkyl, halo, hydroxy, lower alkoxy, amino, lower alkyl-amino, and nitro;R.sub.2 is hydroxy, amino, or lower alkoxy;R.sub.3 is H, lower alkyl, lower acyl, lower alkoxy-acyl, or amnino-acyl;R.sub.4 is H or lower alkyl; and pharmaceutically acceptable salts and esters thereof; are effective inhibitors of GSK3.
摘要翻译：式1化合物：其中R 1是被0-3个选自低级烷基，卤素，羟基，低级烷氧基，氨基，低级烷基 - 氨基和硝基的取代基取代的烷基，环烷基，芳基，芳烷基，杂芳基或杂芳烷基。 R2是羟基，氨基或低级烷氧基; R3是H，低级烷基，低级酰基，低级烷氧基 - 酰基或氨基 - 酰基; R4是H或低级烷基; 及其药学上可接受的盐和酯; 是GSK3的有效抑制剂。

3. 发明授权

US4116594A Embossing apparatus having magnetic roller and flexible embossing plates therefor 失效
标题翻译：压花装置具有磁辊和柔性压花板
公开(公告)号：US4116594A
公开(公告)日：1978-09-26
申请号：US766977
申请日：1977-02-09
申请人： Dale D. Leanna , Allen R. Jorgensen , Thomas R. Curro , Andrew M. Bray
发明人： Dale D. Leanna , Allen R. Jorgensen , Thomas R. Curro , Andrew M. Bray
IPC分类号： B29C33/32 , B29C59/04 , B31F1/07 , B41C1/18 , B44B5/02 , F16C13/00 , B29D7/14
CPC分类号： B29C59/04 , B29C33/32 , B31F1/07 , B41C1/18 , B44B5/026 , F16C13/00 , B31F2201/0717 , B31F2201/0723 , B31F2201/0728 , B31F2201/073 , B31F2201/0743 , B31F2201/0776 , Y10S425/033
摘要： Apparatus for applying a continuous embossing pattern to webs of material such as paper or the like and a method for producing an embossing surface. The apparatus includes rollers which receive a web or webs of such material therebetween and removable embossing plates secured to the surface of the rollers and having an embossing surface for embossing the webs. The rollers are constructed such that they have magnetic properties whereby the embossing plates which are comprised of magnetically attracted material can be held against the roller surface. The plates are positioned in closely adjacent relationship with respect to each other such that they provide a continuous embossing pattern around the surface of the roller. The plates and the rollers also include mutually engaging registering means which permit the plates to be accurately aligned with respect to the roller surface. The plates can thus be readily removed or replaced in the event that they become worn or damaged or in the event that it is desirable to change the embossing pattern frequently. The embossing pattern can be formed in the surface of each of the embossing plates by means of a method of coating the plate surfaces with a photo-chemical resist material, laying a negative of the desired pattern over the photo-chemical coating, directing light through the negative to cause selective deterioration of the coating, and subjecting the plate to a caustic chemical, wash chemical, or etchant to etch the desired pattern into the surface of the plate. The plate may, if necessary, be further machined in order to increase the depth of the etching and to improve the definition and clarity of the embossing pattern.
摘要翻译：用于将连续压花图案施加到诸如纸或类似材料的纸幅的装置以及用于生产压花表面的方法。该装置包括在其间容纳这种材料的腹板或腹板的辊，以及固定到辊的表面的可移除的压花板，并具有用于压花腹板的压花表面。辊被构造成使得它们具有磁性，由此由磁吸引材料构成的压花板可以抵靠辊表面保持。板相对于彼此定位成紧密的关系，使得它们围绕辊的表面提供连续的压花图案。板和辊也包括相互接合的配准装置，其允许板相对于辊表面精确对准。因此，如果它们变得磨损或损坏，或者希望经常改变压花图案，则可以容易地移除或更换板。压花图案可以通过用光致抗蚀剂材料涂覆板表面的方法形成在每个压花板的表面中，在光化学涂层上铺设所需图案的负片，将光引导通过导致涂层的选择性劣化的负面，以及对板进行苛性化学品，洗涤化学品或蚀刻剂以将期望的图案蚀刻到板的表面中。如果需要，可以进一步加工板以增加蚀刻的深度并提高压花图案的清晰度和清晰度。

4. 外观设计

USD395506S Eight-vaned crown for a solid-phase chemical reaction support 失效
公开(公告)号：USD395506S
公开(公告)日：1998-06-23
申请号：US061100
申请日：1996-10-16
申请人： Andrew M. Bray
设计人： Andrew M. Bray

5. 外观设计

USD392039S Four-vaned crown for a solid-phase chemical reaction support 失效
公开(公告)号：USD392039S
公开(公告)日：1998-03-10
申请号：US61090
申请日：1996-10-16
申请人： Andrew M. Bray
设计人： Andrew M. Bray

6. 发明授权

US07053097B1 Inhibitors of glycogen synthase 3 kinase 失效
标题翻译：糖原合成酶3激酶抑制剂
公开(公告)号：US07053097B1
公开(公告)日：2006-05-30
申请号：US09707548
申请日：2000-11-06
申请人： Peter Schultz , David B. Ring , Stephen D. Harrison , Andrew M. Bray
发明人： Peter Schultz , David B. Ring , Stephen D. Harrison , Andrew M. Bray
IPC分类号： C07D473/16 , A61K31/52 , A61P25/28
CPC分类号： C07D473/16
摘要： Compounds of formula 1: wherein R1 is alkyl, cycloalkyl, aryl, aralkyl, heteroaryl, or heteroaralkyl, substituted with 0–3 substituents selected from lower alkyl, halo, hydroxy, lower alkoxy, amino, lower alkyl-amino, and nitro; R2 is hydroxy, amino, or lower alkoxy; R3 is H, lower alkyl, lower acyl, lower alkoxy-acyl, or amino-acyl; R4 is H or lower alkyl; and pharmaceutically acceptable salts and esters thereof; are effective inhibitors of GSK3.
摘要翻译：式1的化合物：其中R 1是被0-3个选自低级烷基，卤素，羟基，低级烷氧基，氨基，低级的取代基取代的烷基，环烷基，芳基，芳烷基，杂芳基或杂芳烷基烷基 - 氨基和硝基; R 2是羟基，氨基或低级烷氧基; R 3是H，低级烷基，低级酰基，低级烷氧基 - 酰基或氨基 - 酰基; R 4是H或低级烷基; 及其药学上可接受的盐和酯; 是GSK3的有效抑制剂。

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