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    • 3. 发明申请
    • Method and apparatus for providing real-time calculation and display of tissue deformation in ultrasound imaging
    • US20050203390A1
    • 2005-09-15
    • US10705087
    • 2003-11-10
    • Hans TorpBjorn OlstadAndreas HeimdalSteinar Bjaerum
    • Hans TorpBjorn OlstadAndreas HeimdalSteinar Bjaerum
    • A61B8/13A61B5/0456A61B8/08G01S7/52G01S15/58G01S15/89A61B8/00
    • A61B8/485A61B5/0456A61B5/7239A61B8/488A61B8/543G01S7/52036G01S7/52038G01S7/52042G01S7/52057G01S7/52085G01S7/52095G01S15/584G01S15/8979
    • An ultrasound system and method for calculation and display of tissue deformation parameters are disclosed. An ultrasound acquisition technique that allows a high frame rate in tissue velocity imaging or strain rate imaging is employed. With this acquisition technique the same ultrasound pulses are used for the tissue image and the Doppler based image. A sliding window technique is used for processing. The tissue deformation parameter strain is also determined by an accumulation of strain rate estimates for consecutive frames over an interval. The interval may be a triggered interval generated by, for example, an R-wave in an ECG trace. The strain calculation may be improved by moving the sample volume from which the strain rate is accumulated from frame-to-frame according to the relative displacement of the tissue within the original sample volume. The relative displacement of the tissue is determined by the instantaneous tissue velocity of the sample volume. An estimation of strain rate based upon a spatial derivative of tissue velocity is improved by adaptively varying the spatial offset, dr. The spatial offset, dr, can be maximized to cover the entire tissue segment (e.g., heart wall width) while still keeping both of the sample volumes at each end of the offset within the tissue segment. This may be accomplished by determining whether various parameters (e.g., grayscale value, absolute power estimate, magnitude of the autocorrelation function with unity temporal lag and/or magnitude of strain correlation) of the sample volumes within in the spatial offset are above a given threshold. Strain rate may be estimated using a generalized strain rate estimator that is based on a weighted sum of two-sample strain rate estimators with different spatial offsets. The weights are proportional to the magnitude of the strain rate correlation estimate for each spatial offset, and thus reduce the effect of noisy, i.e. poorly correlated, samples. An improved signal correlation estimator that uses a spatial lag in addition to the usual temporal lag is disclosed. The spatial lag is found from the tissue velocity. The improved signal correlation estimator can be utilized both in the estimation of strain rate and tissue velocity. Tissue velocity may be estimated in a manner that reduces aliasing while maintaining spatial resolution. Three copies of a received ultrasound signal are bandpass filtered at three center frequencies. The middle of the three center frequencies is centered at the second harmonic of the ultrasound signal. A reference tissue velocity is estimated from the two signals filtered at the outside center frequencies. The reference tissue velocity is used to choose a tissue velocity from a number of tissue velocities estimated from the signal centered at the second harmonic. A method to estimate the strain rate in any direction, not necessarily along the ultrasound beam, based on tissue velocity data from a small region of interest around a sample volume is disclosed. Quantitative tissue deformation parameters, such as tissue velocity, tissue velocity integrals, strain rate and/or strain, may be presented as functions of time and/or spatial position for applications such as stress echo. For example, strain rate or strain values for three different stress levels may be plotted together with respect to time over a cardiac cycle. Parameters which are derived from strain rate or strain velocity, such as peak systolic wall thickening percentage, may be plotted with respect to various stress levels,
    • 6. 发明授权
    • Method and apparatus for providing real-time calculation and display of tissue deformation in ultrasound imaging
    • 用于提供实时计算和显示超声成像组织变形的方法和装置
    • US06352507B1
    • 2002-03-05
    • US09432061
    • 1999-11-02
    • Hans TorpBjorn OlstadAndreas HeimdalSteinar Bjaerum
    • Hans TorpBjorn OlstadAndreas HeimdalSteinar Bjaerum
    • A61B800
    • A61B8/485A61B5/0456A61B5/7239A61B8/488A61B8/543G01S7/52036G01S7/52038G01S7/52042G01S7/52057G01S7/52085G01S7/52095G01S15/584G01S15/8979
    • An ultrasound system and method for calculation and display of tissue deformation parameters are disclosed. An ultrasound acquisition technique that allows a high frame rate in tissue velocity imaging or stain rate imaging is employed. The tissue deformation parameter strain is determined by an accumulation of stain rate estimates for consecutive frames over an interval. The interval may be a triggered interval generated by, for example, an R-wave in an ECG trace. The strain calculation may be improved by moving the sample volume from which the stain rate is accumulated from frame-to-frame according to the relative displacement of the tissue within the original sample volume. The relative displacement of the tissue is defined by the instantaneous tissue velocity of the sample volume. An estimation of strain rate based upon a spatial derivative of tissue velocity is improved by adaptively varying the spatial offset, dr. The spatial offset, dr, can be maximized to cover the entire tissue segment (e.g., heart wall width) while still keeping both of the sample volumes at each end of the offset within the tissue segment. This nay be accomplished by determining whether various parameters (e.g., grayscale value, absolute power estimate, magnitude of the autocorrelation function with unity temporal lag and/or magnitude of strain correlation) of the sample volumes within in the spatial offset are above a given threshold.
    • 公开了用于计算和显示组织变形参数的超声系统和方法。 采用允许组织速度成像或染色率成像中的高帧速率的超声波采集技术。 组织变形参数应变是通过间隔上连续帧的染色率估计的积累来确定的。 该间隔可以是由例如ECG迹线中的R波产生的触发间隔。 通过根据原始样品体积内的组织的相对位移,通过从逐帧移动污染率从其累积的样品体积来改善应变计算。 组织的相对位移由样品体积的瞬时组织速度定义。 通过自适应地改变空间偏移,提高了基于组织速度的空间导数的应变速率的估计。 空间偏移量dr可以最大化以覆盖整个组织段(例如,心脏壁宽度),同时仍保持组织区段内的偏移的每个端部处的两个样本体积。 这可以通过确定在空间偏移内的样本体积的各种参数(例如,灰度值,绝对功率估计,具有单位时间滞后的自相关函数的幅度和/或应变相关的幅度)是否高于给定阈值来实现 。
    • 10. 发明申请
    • Method and apparatus for improving and/or validating 3D segmentations
    • 用于改善和/或验证3D分割的方法和装置
    • US20080281182A1
    • 2008-11-13
    • US11800556
    • 2007-05-07
    • Stein Inge RabbenSevald BergAndreas Heimdal
    • Stein Inge RabbenSevald BergAndreas Heimdal
    • A61B6/00
    • G03B42/06G06T7/12G06T7/149G06T2207/10136G06T2207/30048
    • A method is provided for improving a segmentation of a 3D image and/or validating a segmentation of a 3D image includes rendering an acquired 3D image and a segmentation of the acquired 3D image on a segmentation display that has at least one spatially fixed slice and an interactive slice with a reference mark corresponding to the cursor location in the spatially fixed slice or slices on the display. The method further includes utilizing an interactive user input to update image data of the interactive slice and the reference mark to coincide with the cursor in the spatially fixed slice or slices. The method further includes using the cursor and the reference mark to verify that cursor locations on the boundaries of the segmentation of the acquired 3D image correspond to object boundaries in the image data of the interactive slice.
    • 提供了一种用于改进3D图像的分割和/或验证3D图像的分割的方法,包括在具有至少一个空间固定切片的分割显示上渲染所获取的3D图像和所获取的3D图像的分割,以及 具有对应于空间上固定的切片中的光标位置的参考标记的交互式切片或显示器上的切片。 该方法还包括利用交互式用户输入来更新交互式切片和参考标记的图像数据,使其与空间固定的切片或切片中的光标一致。 该方法还包括使用光标和参考标记来验证所获取的3D图像的分割边界上的光标位置对应于交互式切片的图像数据中的对象边界。