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1. 发明申请

US20080035503A1 OPTICAL DISC CARRYING CASE WITH ACTIVATION WINDOW 审中-公开
标题翻译：带活动窗口的光盘驱动器
公开(公告)号：US20080035503A1
公开(公告)日：2008-02-14
申请号：US11768753
申请日：2007-06-26
申请人： Peter Rentzepis , Richard Selinfreund , Craig Etchegoyen , Alexander Dvornikov
发明人： Peter Rentzepis , Richard Selinfreund , Craig Etchegoyen , Alexander Dvornikov
IPC分类号： G11B33/04
CPC分类号： G11B23/282 , G11B33/0411
摘要： A storage case of storing optical digital data storage media, the case including a cover with a defined area therein that permits transmission of certain energy to the medium stored therein while the area of the cover outside of the defined area does not.
摘要翻译：一种存储光学数字数据存储介质的存储盒，所述壳体包括其中具有限定区域的盖，其允许将某些能量传输到存储在其中的介质，同时所述限定区域外部的区域不存在。

2. 发明授权

US06432610B1 DYE PRECURSOR MOLECULES CHEMICALLY REACTIVE WITH THE LIGHT-ALTERED FORM OF LIGHT-SENSITIVE MOLECULES TO FORM STABLE FLUORESCENT DYE, PARTICULARLY FOR OPTICAL MEMORIES INCLUDING TWO-PHOTON THREE-DIMENSIONAL OPTICAL MEMORIES 有权
标题翻译： DYE前体分子与光敏型分子形式的光敏型分子反应形成稳定的荧光染料，特别是用于光学记忆，包括两光子三维光学记忆
公开(公告)号：US06432610B1
公开(公告)日：2002-08-13
申请号：US09391281
申请日：1999-09-07
申请人： Peter M. Rentzepis , Alexander Dvornikov
发明人： Peter M. Rentzepis , Alexander Dvornikov
IPC分类号： G03C172
CPC分类号： B82Y10/00 , G03C1/732 , G11B7/24 , G11B7/244 , G11B2007/24624 , Y10S430/146
摘要： Dye precursor molecules—normally rhodamine base—held in a transparent matrix are reactive with acids, bases, ions or radicals—and in the case of rhodamine are reactive with acids—to produce dye molecules—i.e., rhodamine—having markedly different spectroscopic properties. Light-sensitive molecules-normally a compound of ortho-nitro-aldehyde, in particular o-nitro-benzaldehyde or, preferably, 1-nitro-2-naphthaldehyde—in the same matrix undergo photochemical reaction when selectively exposed to light so as to form at least one of the acids, bases, ions or radicals with which the dye precursor molecules are reactive—preferably nitroso acid. Chemical reaction of rhodamine base dye precursor molecules with photochemically produced nitroso acid within domains that are radiatively-selected two-dimensionally or within voxels that are radiatively-selected three-dimensionally, by first-frequency “write” radiation—including as may be realized by two-photon absorption—produces stable rhodamine dye in the radiatively-selected domains/voxels. Subsequent illumination with a single, second-frequency “read” radiation induces strong fluorescence in the dye of the written domains/voxels while leaving all chemicals/photochemicals unchanged. The induced fluorescence may be imaged to a detector, such as a charge coupled device (CCD), to reliably realize a high signal-to-noise, non-degrading, optical memory of the write once, read many (WORM) type.
摘要翻译：染料前体分子 - 通常罗丹明碱保持在透明基质中与酸，碱，离子或自由基反应 - 在罗丹明的情况下与酸反应 - 产生染料分子 - 即罗丹明 - 具有明显不同的光谱性质。光敏分子通常是邻硝基醛的化合物，特别是邻硝基苯甲醛或优选1-硝基-2-萘甲醛在同一基质中，当选择性地暴露在光下时会发生光化学反应，形成染料前体分子与其反应的酸，碱，离子或自由基中的至少一种 - 优选亚硝酸。罗丹明碱性染料前体分子与光化学产生的亚硝酸的化学反应在通过第一频率“写入”辐射三维辐射选择的二维或体外辐射选择的域内的光化学产生的亚硝酸，包括可以由双光子吸收 - 在辐射选择的结构域/体素中产生稳定的罗丹明染料。随后的单次，第二频率“读”辐射的照射在书面结构域/体素的染料中引起强烈的荧光，同时使所有化学物质/光化学物质保持不变。诱导的荧光可以被成像到诸如电荷耦合器件（CCD）的检测器，以可靠地实现一次写入（WORM）写入一次读取（WORM）类型的高信噪比，非降级光学存储器。

3. 发明申请

US20120257203A1 APPARATUS AND METHOD FOR LIGHT EMISSION DETECTION FOR IN-DEPTH IMAGING OF TURBID MEDIA 有权
标题翻译：用于轻度发射检测的装置和方法，用于涡轮介质的深度成像
公开(公告)号：US20120257203A1
公开(公告)日：2012-10-11
申请号：US13444696
申请日：2012-04-11
申请人： Enrico Gratton , Alexander Dvornikov , Viera Crosignani
发明人： Enrico Gratton , Alexander Dvornikov , Viera Crosignani
IPC分类号： G01N21/00
CPC分类号： G01N21/6456 , G01N21/4795
摘要： An apparatus and method for in-depth fluorescence imaging using two-photon fluorescence imaging in turbid media. The apparatus includes a detector which can significantly enhance the use of a detection method that allows to efficiently collect scattered fluorescence photons from a wide area of the turbid sample. By using this detector it is possible to perform imaging of turbid samples, simulating brain tissue at depths up to 3 mm, where the two-photon induced fluorescence signal is too weak to be detected by previous means used in conventional two-photon microscopy. The detector separates the excitation and detection optics which allows a more efficient collection of fluorescence and enhancing the possible imaging depth.
摘要翻译：用于在混浊介质中使用双光子荧光成像进行深度荧光成像的装置和方法。该装置包括能够显着增强检测方法的使用的检测器，该检测方法允许有效地从浑浊样品的广泛区域收集散射的荧光光子。通过使用该检测器，可以进行浑浊样品的成像，模拟高达3mm深度的脑组织，其中双光子诱导的荧光信号太弱，无法通过传统双光子显微镜中使用的先前手段检测。检测器分离激发和检测光学器件，其允许更有效地收集荧光并增强可能的成像深度。

4. 发明申请

US20080057328A1 COATING SYSTEM FOR PIRACY-PROTECTED OPTICAL MEDIUM 审中-公开
标题翻译：防护光学介质涂层系统
公开(公告)号：US20080057328A1
公开(公告)日：2008-03-06
申请号：US11768728
申请日：2007-06-26
申请人： Peter Rentzepis , Richard Selinfreund , Craig Etchegoyen , Alexander Dvornikov
发明人： Peter Rentzepis , Richard Selinfreund , Craig Etchegoyen , Alexander Dvornikov
IPC分类号： B32B27/28 , C08F2/46
CPC分类号： C08F2/50 , G11B7/252 , G11B7/254 , G11B20/00086 , Y10T428/31855
摘要： A piracy protection digital recording medium comprising a polymeric layer incorporating an optical state change material in conjunction with a cationic photoinitiator.
摘要翻译：一种盗版保护数字记录介质，其包含结合光学状态改变材料与阳离子光引发剂结合的聚合物层。

5. 发明授权

US08692998B2 Apparatus and method for light emission detection for in-depth imaging of turbid media 有权
标题翻译：用于浑浊介质深度成像的发光检测装置和方法
公开(公告)号：US08692998B2
公开(公告)日：2014-04-08
申请号：US13444696
申请日：2012-04-11
申请人： Enrico Gratton , Alexander Dvornikov , Viera Crosignani
发明人： Enrico Gratton , Alexander Dvornikov , Viera Crosignani
IPC分类号： G01N21/00
CPC分类号： G01N21/6456 , G01N21/4795
摘要： An apparatus and method for in-depth fluorescence imaging using two-photon fluorescence imaging in turbid media. The apparatus includes a detector which can significantly enhance the use of a detection method that allows to efficiently collect scattered fluorescence photons from a wide area of the turbid sample. By using this detector it is possible to perform imaging of turbid samples, simulating brain tissue at depths up to 3 mm, where the two-photon induced fluorescence signal is too weak to be detected by previous means used in conventional two-photon microscopy. The detector separates the excitation and detection optics which allows a more efficient collection of fluorescence and enhancing the possible imaging depth.
摘要翻译：用于在混浊介质中使用双光子荧光成像进行深度荧光成像的装置和方法。该装置包括能够显着增强检测方法的使用的检测器，该检测方法允许有效地从浑浊样品的广泛区域收集散射的荧光光子。通过使用该检测器，可以进行浑浊样品的成像，模拟高达3mm深度的脑组织，其中双光子诱导的荧光信号太弱，无法通过传统双光子显微镜中使用的先前手段检测。检测器分离激发和检测光学器件，其允许更有效地收集荧光并增强可能的成像深度。

6. 发明授权

US06693201B1 Fluorescent photochromic fulgides, particularly for optical memories 失效
标题翻译：荧光光致变色俘获物，尤其适用于光记忆体
公开(公告)号：US06693201B1
公开(公告)日：2004-02-17
申请号：US09391280
申请日：1999-09-07
申请人： Peter M. Rentzepis , Alexander Dvornikov
发明人： Peter M. Rentzepis , Alexander Dvornikov
IPC分类号： C07D40506
CPC分类号： C07D405/06 , G02B5/23 , G11B7/246 , G11B2007/24624
摘要： Photochromic chemicals consisting essentially of colored fluorescent heterocyclic fulgides are particularly suitable for optical memories. The preferred heterocyclic photochromic fulgides consist essentially of colored 2-indolyfulgides capable of excitation by ultraviolet light to fluoresce. These heterocyclic photochromic fulgides are preferably synthesized by process of (1) condensation of 1,3-dimethyl-(5-substituted)indole-2-carboxaldehyde with diethyl IV iospropylidenesuccinate as a key intermediate; followed by (2) hydrolysis; and (3) intramolecular acid anhydride formation.
摘要翻译：基本上由有色荧光杂环捕捉剂组成的光致变色化学品尤其适用于光学存储器。优选的杂环光致变色捕捉剂基本上由能够通过紫外光激发而发出荧光的有色2-取代残基组成。这些杂环光致变色捕捉剂优选通过以下方法合成：（1）1,3-二甲基 - （5-取代的）吲哚-2-甲醛与作为关键中间体的IV ios-丙二烯基琥珀酸二乙酯的缩合; （2）水解; 和（3）分子内酸酐形成。

7. 发明授权

US5734498A Illuminator elements for conventional light microscopes 失效
标题翻译：常规光学显微镜的照明元件
公开(公告)号：US5734498A
公开(公告)日：1998-03-31
申请号：US239683
申请日：1994-05-09
申请人： Tatiana Krasieva , Bruce Tromberg , Alexander Dvornikov , Michael W. Berns
发明人： Tatiana Krasieva , Bruce Tromberg , Alexander Dvornikov , Michael W. Berns
IPC分类号： G02B21/06 , G02B21/00
CPC分类号： G02B21/06
摘要： An inexpensive, simple and easy-to-use illuminator element--consisting of chromophores, particularly fluorophores, and/or light-scattering bodies in a stable, typically a polymer plastic, matrix--completely replaces an infinite set of condensers for a optical microscope, and works equally well with microscope objective lenses of any and all numerical apertures. Illuminator elements of a fluorescent type are employed in combination with a primary source of light that is external to the illuminator element itself, and that is preferably but a simple incandescent light bulb. Nonetheless to be energized with spectrally impure light, each illuminator element produces spectrally pure light(s) of a predetermined color or colors, including a pseudo-white light. Sets of illuminator elements permit the ready production of colored light(s) of any desired spectral characteristics from primary light sources that are no more sophisticated, nor any more expensive, than common electric light bulbs. An illuminator element substantially eliminates most image artifacts while supporting imaging of a quality comparable to the best images obtainable with highest quality condensers correctly matched to the numerical aperture of a microscope's objective lens. Illumination fully comparable to Koehler illumination is obtained virtually effortlessly simply by placing an illuminator element near, and normally directly upon, a specimen that is typically mounted upon a microscope slide.
摘要翻译：由稳定的，通常为聚合物塑料的基质中的发色团，特别是荧光团和/或光散射体组成的廉价，简单且易于使用的照明元件完全替代了用于光学显微镜的无限集电容器，并且与任何和所有数值孔径的显微镜物镜同样适用。荧光灯的照明元件与照明元件本身外部的主要光源结合使用，并且优选地是简单的白炽灯泡。尽管如此，通过光谱不纯的光被激发，每个照明器元件产生包括伪白光的预定颜色或颜色的光谱纯净的光。照明器元件的集合允许从普通电灯泡那里准备生产来自主光源的任何期望的光谱特征的彩色光，其不再复杂，也不昂贵。照明元件基本上消除了大多数图像伪影，同时支持与可与正确匹配于显微镜物镜的数值孔径的最高质量电容器可获得的最佳图像相当的质量成像。通过将照明元件放置在通常安装在显微镜载玻片上的样本并且通常直接放置在通常安装在显微镜载玻片上的样本上，几乎毫不费力地获得与Koehler照明完全相当的照明。

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