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1. 发明授权

US08794013B2 Method and system for nucleation control in a controlled rate freezer (CRF) 有权
标题翻译：控制率冷冻机（CRF）中成核控制的方法和系统
公开(公告)号：US08794013B2
公开(公告)日：2014-08-05
申请号：US13097724
申请日：2011-04-29
申请人： Ying Zhou , Theodore H. Gasteyer, III , Nigel J. Grinter , Alan T. Cheng , Yeu-Chuan Simon Ho , Robert R. Sever
发明人： Ying Zhou , Theodore H. Gasteyer, III , Nigel J. Grinter , Alan T. Cheng , Yeu-Chuan Simon Ho , Robert R. Sever
IPC分类号： F25D25/00 , G01N1/22 , C12M3/00 , A01N1/02 , F25D3/10 , F25D29/00
CPC分类号： A01N1/0289 , A01N1/0257 , A01N1/0284 , F25D3/102 , F25D29/001
摘要： A method and system for controlled rate freezing and nucleation of materials is provided. The presently disclosed system and method provides the ability to rapidly cool the materials contained in vials or other containers within a cooling unit via forced convective cooling using a laminar and uniform flow of cryogen in proximity to the plurality of vials disposed within the cooling unit. The rapid cooling of the biological materials is achieved by precisely controlling and adjusting the temperature of the cryogen being introduced to the system as a function of time. The presently disclosed methods to systems also provide nucleation control via temperature quench and depressurized nucleation control.
摘要翻译：提供了控制速率冷冻和成核的方法和系统。本公开的系统和方法提供了通过强制对流冷却来快速冷却包含在冷却单元内的小瓶或其他容器中的材料的能力，其中使用层流和均匀流动的冷冻剂靠近设置在冷却单元内的多个小瓶。生物材料的快速冷却是通过精确地控制和调节作为时间的函数引入到系统中的冷冻剂的温度来实现的。目前公开的系统方法还通过温度骤冷和减压成核控制提供成核控制。

2. 发明申请

US20140007615A1 SYSTEM AND METHOD FOR PURIFICATION OF SILANE USING LIQUID NITROGEN IN A POLYSILICON PRODUCTION PROCESS 审中-公开
标题翻译：在多晶硅生产过程中使用液氮的硅烷进行纯化的系统和方法
公开(公告)号：US20140007615A1
公开(公告)日：2014-01-09
申请号：US13884647
申请日：2011-11-08
申请人： Alan T. Cheng , De-Cheng Xie , Zhijie Sun
发明人： Alan T. Cheng , De-Cheng Xie , Zhijie Sun
IPC分类号： F25J3/00
CPC分类号： F25J3/00 , C01B33/035 , H02K21/38
摘要： A system and method for improved cryogenic cooling of process streams in polysilicon manufacturing is provided. The disclosed system and method provides for the cryogenic cooling of a silane and hydrogen process stream during the manufacture of polysilicon with concurrent recovery of refrigeration capacity from the vaporized nitrogen as well as the recovery of refrigeration capacity from the cold hydrogen stream. The improved cryogenic cooling system and method reduces the overall consumption of liquid nitrogen without sacrificing cooling performance of the cryogenic cooling of the silane and hydrogen process stream.
摘要翻译：提供了一种用于改善多晶硅制造中工艺流的低温冷却的系统和方法。所公开的系统和方法提供了在制造多晶硅期间硅烷和氢工艺流的低温冷却，同时从蒸发的氮回收制冷能力以及从冷氢流回收制冷能力。改进的低温冷却系统和方法降低了液氮的总体消耗，而不牺牲硅烷和氢气工艺流的低温冷却的冷却性能。

3. 发明申请

US20130323714A1 SYSTEM AND METHOD FOR MICRO-AERATION BASED FERMENTATION 审中-公开
标题翻译：基于微生物发酵的系统和方法
公开(公告)号：US20130323714A1
公开(公告)日：2013-12-05
申请号：US13908462
申请日：2013-06-03
申请人： Alan T. Cheng , Ying Zhou , Paul W. Belanger , Jennifer G. Bugayong
发明人： Alan T. Cheng , Ying Zhou , Paul W. Belanger , Jennifer G. Bugayong
IPC分类号： C12M1/00
CPC分类号： C12M41/48 , C12M21/12 , C12M27/00 , C12M29/06 , C12M29/24 , C12M41/32 , C12M41/34
摘要： A method and apparatus for micro-aeration of large scale fermentation systems is provided. The micro-aeration system includes a fermentation reactor, a sparging apparatus, and a micro-aeration gas mixture delivered to the fermentation reactor via the sparging apparatus. The micro-aeration gas mixture is a very low oxygen concentration mixture comprising an oxygen containing gas and an inert carrier gas that is preferably recycled through the fermentation reactor. The inert carrier gas is preferably nitrogen whereas the oxygen containing gas is oxygen or and is introduced to the fermentation reactor at a minimum superficial velocity of about 0.02 m/sec to produce a uniform dispersion of the oxygen/air throughout the fermentation broth while concurrently mixing the entire fermentation broth. The micro-aeration method and apparatus further comprises a controller operatively coupled to one or more control valves for regulating the micro-aeration conditions in the fermentation reactor.
摘要翻译：提供了一种用于大规模发酵系统微通气的方法和装置。微曝气系统包括通过喷射装置输送到发酵反应器的发酵反应器，喷射装置和微通气气体混合物。微通气气体混合物是包含含氧气体和惰性载气的非常低的氧浓度混合物，其优选通过发酵反应器再循环。惰性载气优选为氮气，而含氧气体为氧气，或以约0.02m / sec的最小表观速度引入发酵反应器，以产生氧气/空气在整个发酵液中的均匀分散，同时混合整个发酵液。微曝气方法和装置还包括操作地耦合到一个或多个控制阀的控制器，用于调节发酵反应器中的微通气条件。

4. 发明授权

US06355292B1 Precarbonation process to reduce foaming 失效
标题翻译：预碳酸化工艺减少发泡
公开(公告)号：US06355292B1
公开(公告)日：2002-03-12
申请号：US09492759
申请日：2000-01-27
申请人： Alan T. Cheng , Pedro L. Durao
发明人： Alan T. Cheng , Pedro L. Durao
IPC分类号： C12G106
CPC分类号： A23L2/54
摘要： The tendency of carbonated beverage to generate excessive foam when it is produced and bottled is reduced in a process including: (a) providing water or a mixture of water and syrup, which contains oxygen or air dissolved therein, and maintaining a pressure greater than atmospheric thereon; (b) saturating said mixture with carbon dioxide, and feeding the resultant mixture to step (c), while maintaining sufficient pressure thereon that no dissolved gas evolves therefrom; and (c) removing dissolved oxygen or air from the mixture formed in step (b) while dissolving additional carbon dioxide into said mixture and maintaining over said mixture a pressure greater than atmospheric.
摘要翻译：碳酸饮料在生产和装瓶过程中产生过量泡沫的趋势在一个过程中减少，包括：（a）提供水或水和糖浆的混合物，其中含有溶解在其中的氧气或空气，并保持大于大气压上; （b）用二氧化碳使所述混合物饱和，并将所得混合物进料至步骤（c），同时在其上保持足够的压力，不会从其中产生溶解气体; 和（c）从步骤（b）中形成的混合物中除去溶解的氧气或空气，同时将额外的二氧化碳溶解在所述混合物中并保持所述混合物的压力大于大气压。

5. 发明授权

US5302325A In-line dispersion of gas in liquid 失效
标题翻译：气体在液体中的在线分散
公开(公告)号：US5302325A
公开(公告)日：1994-04-12
申请号：US587860
申请日：1990-09-25
申请人： Alan T. Cheng
发明人： Alan T. Cheng
IPC分类号： B01F3/04 , B01F5/00 , B01F5/04 , B01F5/06
CPC分类号： B01F5/061 , B01F5/0416 , Y10S261/78
摘要： The dispersion of a gas in a liquid is enhanced by accelerating a gas/liquid mixture to supersonic velocity, with subsequent deacceleration, in a conical in-line mixer.
摘要翻译：通过在锥形在线混合器中将气体/液体混合物加速至超音速，随后进行减速，增强气体在液体中的分散。

6. 发明授权

US5061406A In-line gas/liquid dispersion 失效
标题翻译：在线气/液分散
公开(公告)号：US5061406A
公开(公告)日：1991-10-29
申请号：US587745
申请日：1990-09-25
申请人： Alan T. Cheng
发明人： Alan T. Cheng
IPC分类号： B01F3/04 , B01F5/04 , B01J10/00 , B01J19/00 , B01J19/26
CPC分类号： B01F5/0416 , B01J10/002 , B01J19/006 , B01J19/26 , B01J2219/00162 , B01J2219/00774 , Y10S261/56 , Y10S261/75 , Y10S261/78
摘要： The dispersion of a gas in a liquid is enhanced by the use of an adjustable conical mixer to control the flow of a gas/liquid mixture to a venturi device used to accelerate the mixture to a supersonic vclocity with subsequent deacceleration to subsonic velocity to produce sonic shock waves in the mixture.

7. 发明授权

US08820097B2 Method and system for regulating the mixture of cryogen liquid and warm gas for a controlled rate cryogenic chiller or freezing system 有权
标题翻译：用于调节低温冷冻机或冷冻系统的冷冻液和暖气混合物的方法和系统
公开(公告)号：US08820097B2
公开(公告)日：2014-09-02
申请号：US13097763
申请日：2011-04-29
申请人： Alan T. Cheng , Yeu-Chuan Simon Ho , Ying Zhou
发明人： Alan T. Cheng , Yeu-Chuan Simon Ho , Ying Zhou
IPC分类号： F25D25/00 , G01N1/22 , C12M3/00 , A01N1/02 , F25D3/10 , F25D29/00
CPC分类号： A01N1/0257 , A01N1/0284 , A01N1/0289 , F25D3/102 , F25D29/001
摘要： A method and system for controlled rate freezing and nucleation of materials is provided. The presently disclosed system and method provides the ability to rapidly cool the materials contained in vials or other containers within a cooling unit via forced convective cooling using a laminar and uniform flow of cryogen in proximity to the plurality of vials disposed within the cooling unit. The rapid cooling of the biological materials is achieved by precisely controlling and adjusting the temperature of the cryogen being introduced to the system as a function of time. The presently disclosed methods to systems also provide nucleation control via temperature quench and depressurized nucleation control.
摘要翻译：提供了控制速率冷冻和成核的方法和系统。本公开的系统和方法提供了通过强制对流冷却来快速冷却包含在冷却单元内的小瓶或其他容器中的材料的能力，其中使用层流和均匀流动的冷冻剂靠近设置在冷却单元内的多个小瓶。生物材料的快速冷却是通过精确地控制和调节作为时间的函数引入到系统中的冷冻剂的温度来实现的。目前公开的系统方法还通过温度骤冷和减压成核控制提供成核控制。

8. 发明申请

US20140000310A1 SYSTEM AND METHOD FOR CRYOGENIC COOLING OF A PROCESS STREAM WITH ENHANCED RECOVERY OF REFRIGERATION 审中-公开
标题翻译：具有加强制冷恢复的工艺流程的低温冷却系统和方法
公开(公告)号：US20140000310A1
公开(公告)日：2014-01-02
申请号：US13884708
申请日：2011-11-08
申请人： Alan T. Cheng , De-Cheng Xie Xie , Zhijie Sun
发明人： Alan T. Cheng , De-Cheng Xie Xie , Zhijie Sun
IPC分类号： F25J3/06
CPC分类号： F25J3/06 , C01B33/02 , H02K21/38
摘要： A system and method for improved cryogenic cooling of process gases is provided. The disclosed system and method provides for the cryogenic cooling of a silane and hydrogen gas process stream during the manufacture of polysilicon with concurrent recovery of refrigeration capacity from the vaporized nitrogen as well as the recovery of refrigeration capacity from the cold hydrogen gas stream. The improved cryogenic cooling system and method reduces the overall consumption of liquid nitrogen without sacrificing cooling performance of the cryogenic cooling of the silane and hydrogen gas process stream.
摘要翻译：提供了一种用于改善工艺气体的低温冷却的系统和方法。所公开的系统和方法提供了在制造多晶硅期间硅烷和氢气工艺流的低温冷却，同时从蒸发的氮气中回收制冷量，以及从冷氢气流中回收制冷量。改进的低温冷却系统和方法降低了液氮的总体消耗，而不牺牲硅烷和氢气工艺流的低温冷却的冷却性能。

9. 发明授权

US5394827A Draft tube, direct contact cryogenic crystallizer 失效
标题翻译：引流管，直接接触式低温结晶器
公开(公告)号：US5394827A
公开(公告)日：1995-03-07
申请号：US272978
申请日：1994-07-15
申请人： Alan T. Cheng
发明人： Alan T. Cheng
IPC分类号： B01D9/02 , B01D9/00 , B01J8/22 , B01J19/00 , B01J19/26 , C30B7/08
CPC分类号： B01J19/26 , B01D9/0009 , B01J8/226 , Y10T117/10 , Y10T117/1024 , Y10T117/1096
摘要： A direct contact cryogenic crystallizer having a vertically oriented draft tube into which cryogenic fluid is injected at a high velocity along with warm gas and through which a crystal slurry is drawn for subsequent cooling and agitation for the production of crystals.
摘要翻译：一种直接接触式低温结晶器，其具有垂直定向的导流管，低温流体与暖气一起以高速注入其中，并通过该低温液体引入晶体浆液用于随后的冷却和搅拌以产生晶体。

10. 发明授权

US10744468B2 System and method for feeding gas into liquid 有权
公开(公告)号：US10744468B2
公开(公告)日：2020-08-18
申请号：US15678465
申请日：2017-08-16
申请人： Alan T Cheng , Yeu-Chuan Simon Ho , Balazs Hunek
发明人： Alan T Cheng , Yeu-Chuan Simon Ho , Balazs Hunek
IPC分类号： B01F5/04 , B01F3/04 , B01F13/10 , A01K63/04 , A01K61/10
摘要： Disclosed are a system and a method for dissolving water-soluble gas such as oxygen into water, employing microporous membrane.

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