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1. 发明授权

US07875294B2 Method of attenuating bruise formation 有权
标题翻译：减轻瘀伤形成的方法
公开(公告)号：US07875294B2
公开(公告)日：2011-01-25
申请号：US11528780
申请日：2006-09-28
申请人： Robert W. Sessions , Roger Sessions, legal representative , Alan R. Kahn
发明人： Robert W. Sessions , Alan R. Kahn
IPC分类号： A61K9/14
CPC分类号： A61L15/48 , A61K31/717 , A61K31/736 , A61K31/765 , A61K36/48 , A61K38/39 , A61K45/06 , A61L15/225 , A61L15/26 , A61L15/28 , A61L15/42 , A61L15/425 , A61L15/44 , A61L2300/402 , C08G18/10 , C08G18/4833 , C08G2101/0008 , C08L75/04 , A61K2300/00 , C08L2666/26
摘要： The present invention provides a method of attenuating the formation or reducing the severity of a bruise in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of the skin in an amount and at a location sufficient to attenuate formation of or reduce the severity of bruising.
摘要翻译：本发明提供了一种通过将包含亲水性泡沫基质和聚合物亲水剂的组合物以一定的量施用到皮肤表面的一部分来减弱患者组织中的瘀伤的形成或降低其严重性的方法，以及在足以减轻瘀伤的形成或降低瘀伤严重性的位置。

2. 发明授权

US5772600A Coherent pattern identification in non-stationary periodic data and blood pressure measurement using same 失效
标题翻译：非平稳周期数据中的相干模式识别和使用相同模式的血压测量
公开(公告)号：US5772600A
公开(公告)日：1998-06-30
申请号：US665362
申请日：1996-06-17
申请人： Alan R. Kahn , Dennis E. Bahr , Kurt W. Allen
发明人： Alan R. Kahn , Dennis E. Bahr , Kurt W. Allen
IPC分类号： A61B5/0225 , A61B5/0285 , A61B5/02
CPC分类号： A61B5/02208 , A61B5/0225 , A61B5/0285
摘要： A method and apparatus for automatically recognizing meaningful patterns in non-stationary periodic data is provided. The invention may be used in making measurements of physiological phenomena, such as arterial blood pressure, wherein data of interest is undergoing small changes in timing and magnitude in succeeding cycles, and wherein noise artifacts are detected along with the data of interest. Data points of interest are identified by grouping all received data points into family groups of multi-dimensional data points wherein each data point in the family group has dimensional values similar to at least one other data point in the family. The present invention may preferably be employed for the determination of a patient's systolic and diastolic blood pressure levels. For this application, the data points include a time dimension value corresponding to the delay time between an ECG signal and the detection of a potential blood pressure sound by a microphone placed in an inflatable cuff on the arm of a patient, and a magnitude dimension value corresponding to the cuff pressure at the time of the potential blood pressure sound detection. Data points are collected for a series of cuff pressures ranging from above the systolic blood pressure level of the patient to below the diastolic blood pressure level of the patient. The highest and lowest pressures of data points in the family containing the largest number of data points are used to derive the systolic and diastolic blood pressure levels of the patient, respectively.
摘要翻译：提供了一种在非平稳周期数据中自动识别有意义的模式的方法和装置。本发明可以用于测量生理现象，例如动脉血压，其中感兴趣的数据在随后的周期中的时间和量值经历小的变化，并且其中检测到噪声伪像以及感兴趣的数据。通过将所有接收到的数据点分组成多维数据点的族组来识别感兴趣的数据点，其中家庭组中的每个数据点具有与家族中的至少一个其他数据点相似的尺寸值。本发明可优选用于确定患者的收缩压和舒张压水平。对于该应用，数据点包括对应于ECG信号与放置在患者的手臂上的可充气袖带中的麦克风的潜在血压声音的延迟时间之间的时间维度值，以及幅度尺寸值对应于潜在血压声音检测时的袖带压力。收集数据点，用于从患者的收缩压水平高于患者的舒张压水平以下的一系列袖带压。使用包含最多数据点的家庭中数据点的最高和最低压力分别用于导出患者的收缩压和舒张压水平。

3. 发明授权

US4860759A Vital signs monitor 失效
标题翻译：生命体征监测
公开(公告)号：US4860759A
公开(公告)日：1989-08-29
申请号：US93952
申请日：1987-09-08
申请人： Alan R. Kahn , Jennifer K. Chandler
发明人： Alan R. Kahn , Jennifer K. Chandler
IPC分类号： A61B5/0205 , A61B5/0215 , G06F19/00
CPC分类号： A61B5/721 , A61B5/0205 , A61B5/02108 , A61B5/0816 , G06F19/3406 , A61B5/0402 , A61B5/14551 , G06F19/322
摘要： A vital signs monitor includes an ECG sensor, an oximetric finger probe, a respiration impedance sensor, a respiration strain gauge, and a blood pressure cuff with a pressure sensor. Signals generated by these sensors are processed by a microcomputer which is programmed to cross-reference data from multiple channels in order to improve accuracy. The microcomputer is programmed to select the more regular pulses from the ECG sensor and the finger probe to arrive at a better measure of heart rate. In addition, the microcomputer is programmed to use the strain gauge signal to remove artifacts from the signal generated by the impedance sensor. In this way a more artifact-free measure of respiration rate is obtained. Blood pressure is measured by using timing information derived from pulses sensed by the oximetric finger probe in combination with signals generated by the blood pressure cuff pressure sensor to determine systolic and diastolic pressures of the subject. A calibrated blood pressure waveform is generated automatically from the oximetric finger probe and the blood pressure cuff.
摘要翻译：生命体征监测器包括ECG传感器，血氧指数探针，呼吸阻抗传感器，呼吸应变计和具有压力传感器的血压袖带。由这些传感器生成的信号由微型计算机处理，微型计算机被编程为从多个通道交叉参考数据，以提高精度。微型计算机被编程为从ECG传感器和手指探针中选择更规则的脉冲以获得更好的心率测量。此外，微型计算机被编程为使用应变计信号从阻抗传感器产生的信号中去除伪影。以这种方式，获得了更无伪影的呼吸速率测量。通过使用由血压指形探针感测的脉冲导出的定时信息与由血压袖带压力传感器产生的信号结合起来确定受试者的收缩压和舒张压来测量血压。血氧饱和度测量仪和血压袖带自动产生校准血压波形。

4. 发明授权

US08486454B2 Method of attenuating neurogenic pain 有权
标题翻译：减轻神经源性疼痛的方法
公开(公告)号：US08486454B2
公开(公告)日：2013-07-16
申请号：US11540460
申请日：2006-09-29
申请人： Robert W. Sessions , Alan R. Kahn
发明人： Robert W. Sessions , Alan R. Kahn
IPC分类号： A61K9/14
CPC分类号： A61L15/48 , A61K31/717 , A61K31/736 , A61K31/765 , A61K36/48 , A61K38/39 , A61K45/06 , A61L15/225 , A61L15/26 , A61L15/28 , A61L15/42 , A61L15/425 , A61L15/44 , A61L2300/402 , C08G18/10 , C08G18/4833 , C08G2101/0008 , C08L75/04 , A61K2300/00 , C08L2666/26
摘要： The present invention provides a method of attenuating the formation or reducing the severity of neurogenic pain in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of the skin in an amount and at a location sufficient to attenuate formation of or reduce the severity of neurogenic pain.
摘要翻译：本发明提供了一种通过将包含亲水性泡沫基质和聚合物亲水剂的组合物以一定的量施用到皮肤表面的一部分来减弱患者组织中神经源性疼痛的形成或降低其严重程度的方法，在足以减轻神经源性疼痛的形成或降低神经源性疼痛的严重性的位置。

5. 发明授权

US07709005B2 Method of attenuating neurogenic swelling or neurogenic inflammation 有权
标题翻译：减轻神经源性肿胀或神经源性炎症的方法
公开(公告)号：US07709005B2
公开(公告)日：2010-05-04
申请号：US11541153
申请日：2006-09-29
申请人： Robert W. Sessions , Alan R. Kahn
发明人： Robert W. Sessions , Alan R. Kahn
IPC分类号： A61K31/00 , A61K9/14 , A61K36/00
CPC分类号： A61L15/48 , A61K31/717 , A61K31/736 , A61K31/765 , A61K36/48 , A61K38/39 , A61K45/06 , A61L15/225 , A61L15/26 , A61L15/28 , A61L15/42 , A61L15/425 , A61L15/44 , A61L2300/402 , C08G18/10 , C08G18/4833 , C08G2101/0008 , C08L75/04 , A61K2300/00 , C08L2666/26
摘要： The present invention provides a method of attenuating the formation or reducing the severity of neurogenic swelling and/or neurogenic inflammation in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of the skin in an amount and at a location sufficient to attenuate formation of or reduce the severity of neurogenic swelling and/or neurogenic inflammation.
摘要翻译：本发明提供了一种通过将包含亲水性泡沫基质和聚合物亲水剂的组合物施用到患者组织的表面的一部分来减弱患者组织中神经源性肿胀和/或神经源性炎症的严重程度的形成或降低的方法皮肤的量和足以减轻神经源性肿胀和/或神经源性炎症的严重程度的形成或降低的位置。

6. 发明授权

US07078055B2 Method of attenuating swelling or inflammation 有权
公开(公告)号：US07078055B2
公开(公告)日：2006-07-18
申请号：US10175109
申请日：2002-06-19
申请人： Robert W. Sessions , Alan R. Kahn
发明人： Robert W. Sessions , Alan R. Kahn
IPC分类号： A61K9/14
CPC分类号： A61L15/48 , A61K31/717 , A61K31/736 , A61K31/765 , A61K36/48 , A61K38/39 , A61K45/06 , A61L15/225 , A61L15/26 , A61L15/28 , A61L15/42 , A61L15/425 , A61L15/44 , A61L2300/402 , C08G18/10 , C08G18/4833 , C08G2101/0008 , C08L75/04 , A61K2300/00 , C08L2666/26
摘要： The present invention provides a method of attenuating swelling or inflammation in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent capable of absorbing water to a portion of the surface of the skin of the patient in an amount and at a location sufficient to attenuate swelling or inflammation.

7. 发明授权

US06451301B1 Analgesic and antinociceptive methods 有权
标题翻译：止痛和镇痛方法
公开(公告)号：US06451301B1
公开(公告)日：2002-09-17
申请号：US09326836
申请日：1999-06-07
申请人： Robert W. Sessions , Alan R. Kahn
发明人： Robert W. Sessions , Alan R. Kahn
IPC分类号： A61K3174
CPC分类号： A61L15/48 , A61K31/717 , A61K31/736 , A61K31/765 , A61K36/48 , A61K38/39 , A61K45/06 , A61L15/225 , A61L15/26 , A61L15/28 , A61L15/42 , A61L15/425 , A61L15/44 , A61L2300/402 , C08G18/10 , C08G18/4833 , C08G2101/0008 , C08L75/04 , A61K2300/00 , C08L2666/26
摘要： The present invention provides a method of attenuating the response of nociceptors to noxious stimuli by applying a composition comprising a hydrophilic foam substrate, a polymeric hydrophilic agent capable of absorbing water to the surface of the skin. In other aspects, the present invention provides a method of preventing the formation of a bruise in traumatized tissue, a method of attenuating swelling, a method of attenuating neurogenic inflammatory response, and a method of reducing the sensation of pain by applying like compositions to the surface of the skin of patients.
摘要翻译：本发明提供了一种通过将包含亲水性泡沫底物，能够吸收水的聚合亲水剂的组合物施用到皮肤表面来减弱伤害感受器对有害刺激物的反应的方法。在其他方面，本发明提供了一种防止在创伤组织中形成瘀伤的方法，减轻肿胀的方法，减轻神经源性炎性反应的方法，以及通过将类似组合物施用于患者皮肤表面。

8. 发明授权

US4354497A Cardiac depolarization detection apparatus 失效
标题翻译：心脏去极化检测装置
公开(公告)号：US4354497A
公开(公告)日：1982-10-19
申请号：US799258
申请日：1977-05-23
申请人： Alan R. Kahn
发明人： Alan R. Kahn
IPC分类号： A61B5/0468 , A61N1/365 , A61N1/36
CPC分类号： A61B5/0468 , A61N1/365
摘要： Apparatus which detects ventricular depolarizations originating at an ectopic focus. Ventricular depolarization is sensed at a plurality of areas of the heart including one area within the interventricular septum or near the right ventricular apex. Logic circuity responds to the sensed depolarizations to discriminate between normal and abnormal origination of an impulse propagated through the ventricular conduction system. A signal representative of such abnormal impulse origination may be employed in any desired manner.
摘要翻译：检测源于异位焦点的心室去极化的装置。在心脏的多个区域感测到心室去极化，包括室间隔内的一个区域或右心室顶点附近。逻辑电路响应于感测到的去极化，以区分通过心室传导系统传播的脉冲的正常和异常发生。代表这种异常脉冲起始的信号可以以任何期望的方式使用。

9. 发明申请

US20100267640A1 Method of Attenuating Neurogenic Swelling or Neurogenic Inflammation 审中-公开
标题翻译：减少神经源性肿胀或神经源性炎症的方法
公开(公告)号：US20100267640A1
公开(公告)日：2010-10-21
申请号：US12767065
申请日：2010-04-26
申请人： Robert W. Sessions , Alan R. Kahn
发明人： Robert W. Sessions , Alan R. Kahn
IPC分类号： A61K38/39 , A61K47/36 , A61K47/34 , A61K38/02 , A61K31/618 , A61K31/203 , A61P29/00
CPC分类号： A61L15/48 , A61K31/717 , A61K31/736 , A61K31/765 , A61K36/48 , A61K38/39 , A61K45/06 , A61L15/225 , A61L15/26 , A61L15/28 , A61L15/42 , A61L15/425 , A61L15/44 , A61L2300/402 , C08G18/10 , C08G18/4833 , C08G2101/0008 , C08L75/04 , A61K2300/00 , C08L2666/26
摘要： The present invention provides a method of attenuating the formation or reducing the severity of neurogenic swelling and/or neurogenic inflammation in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of the skin in an amount and at a location sufficient to attenuate formation of or reduce the severity of neurogenic swelling and/or neurogenic inflammation.
摘要翻译：本发明提供了一种通过将包含亲水性泡沫基质和聚合物亲水剂的组合物施用到患者组织的表面的一部分来减弱患者组织中神经源性肿胀和/或神经源性炎症的严重程度的形成或降低的方法皮肤的量和足以减轻神经源性肿胀和/或神经源性炎症的严重程度的形成或降低的位置。

10. 发明授权

US07625585B2 Method of attenuating neurogenic bruise formation 有权
标题翻译：减轻神经源性瘀伤形成的方法
公开(公告)号：US07625585B2
公开(公告)日：2009-12-01
申请号：US11440550
申请日：2006-05-25
申请人： Robert W. Sessions , Alan R. Kahn
发明人： Robert W. Sessions , Alan R. Kahn
IPC分类号： A61K9/14
CPC分类号： A61L15/48 , A61K31/717 , A61K31/736 , A61K31/765 , A61K36/48 , A61K38/39 , A61K45/06 , A61L15/225 , A61L15/26 , A61L15/28 , A61L15/42 , A61L15/425 , A61L15/44 , A61L2300/402 , C08G18/10 , C08G18/4833 , C08G2101/0008 , C08L75/04 , A61K2300/00 , C08L2666/26
摘要： The present invention provides a method of attenuating the formation or reducing the severity of a neurogenic bruise in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent to a portion of the surface of the skin in an amount and at a location sufficient to attenuate formation of or reduce the severity of bruising.
摘要翻译：本发明提供了通过将包含亲水性泡沫基质和聚合物亲水剂的组合物以一定量施用到皮肤表面的一部分来减弱患者组织中神经源性瘀伤的形成或降低其严重程度的方法并且在足以减弱瘀伤的形成或降低瘀伤严重性的位置。

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