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1. 发明公开

US20240382462A1 PRESBYOPIA TREATMENTS 审中-公开
公开(公告)号：US20240382462A1
公开(公告)日：2024-11-21
申请号：US18621624
申请日：2024-03-29
申请人： Allergan, Inc.
发明人： Michael R. Robinson , Mohammed Dibas , Jaya Giyanani , Anuradha Gore , Sungwook Lee , Haixia Liu , Aileen Morgan , Jihao Zhou
IPC分类号： A61K31/4178 , A61P27/10
CPC分类号： A61K31/4178 , A61P27/10
摘要： Described herein are methods and compositions for the treatment of ocular conditions and for the improvement of vision parameters using pharmaceutically acceptable ophthalmic pilocarpine formulations. A nonlimiting example of an ocular condition that may be treated with the methods and compositions disclosed herein is presbyopia.

2. 发明公开

US20240299480A1 STABILIZED OMEGA-3 OPHTHALMIC COMPOSITIONS 审中-公开
公开(公告)号：US20240299480A1
公开(公告)日：2024-09-12
申请号：US18411666
申请日：2024-01-12
申请人： Allergan, Inc.
发明人： Anuradha V. Gore , Jaya Giyanani , Sukhon Likitlersuang
IPC分类号： A61K36/55 , A61K9/00 , A61K31/05 , A61K31/085
CPC分类号： A61K36/55 , A61K9/0048 , A61K31/05 , A61K31/085
摘要： Stabilized ophthalmic compositions containing omega-3 oils are provided, which are useful as artificial tears and as ophthalmic compositions to diagnose, treat, or prevent keratoconjunctivitis or dry eye syndrome in a human or other mammal.

3. 发明公开

US20240216512A1 INTRACAMERAL IMPLANT FOR TREATMENT OF AN OCULAR CONDITION 审中-公开
公开(公告)号：US20240216512A1
公开(公告)日：2024-07-04
申请号：US18386522
申请日：2023-11-02
申请人： Allergan, Inc.
发明人： Andres Garcia , Benjamin Maynor , Janet Tully , Benjamin Robinson Yerxa , Tomas Navratil , Sanjib Kumar Das
IPC分类号： A61K47/34 , A61K9/00 , A61K31/5575
CPC分类号： A61K47/34 , A61K9/0051 , A61K31/5575
摘要： The disclosure teaches precisely engineered biodegradable drug delivery systems and methods of making and utilizing such systems. In aspects, the biodegradable drug delivery systems taught herein comprise ocular implants having a desired extended drug release profile suitable for treating elevated intraocular pressure.

4. 发明授权

US11992668B2 Injection device 有权
公开(公告)号：US11992668B2
公开(公告)日：2024-05-28
申请号：US16358553
申请日：2019-03-19
申请人： Allergan, Inc.
发明人： Ahmet Tezel , Kevin McNerney , Christopher S. Mudd , Blake R. Storie , Bastien Mandaroux
IPC分类号： A61M5/34 , A61M5/32
CPC分类号： A61M5/347 , A61M5/3293 , A61M2210/04
摘要： A needle assembly for an injection device is provided to facilitate delivery of a dermal filler. The assembly includes a cannula and a hub. The hub can be coupled to a syringe. The hub includes an inner bore that has a proximal retention section, a stepped section, and a cannula retention section. The stepped section, the proximal retention section, and the cannula retention section are configured to reduce the dead space within the inner bore for preventing detachment of the hub from the syringe during an injection procedure.

5. 外观设计

USD1027647S1 Bottle holder 有权
公开(公告)号：USD1027647S1
公开(公告)日：2024-05-21
申请号：US29721515
申请日：2020-01-21
申请人： Allergan, Inc.
设计人： Matthew R. Christy , Michael J. Regn
摘要： FIG. 1 is a front, top perspective view of a bottle holder;
FIG. 2 is a rear, bottom perspective view of the bottle holder of FIG. 1;
FIG. 3 is a front plan view of the bottle holder of FIG. 1;
FIG. 4 is a rear plan view of the bottle holder of FIG. 1;
FIG. 5 is a left side view of the bottle holder of FIG. 1;
FIG. 6 is a right side view of the bottle holder of FIG. 1;
FIG. 7 is a bottom plan view of the bottle holder of FIG. 1;
FIG. 8 is a top plan view of the bottle holder of FIG. 1;
FIG. 9 is a front, top perspective view of the bottle holder of FIG. 1, wherein a top portion thereof is in an open position; and,
FIG. 10 is a rear, bottom perspective view of the bottle holder of FIG. 1, wherein the top portion thereof is in the open position.
The broken lines shown in the drawings depict portions of the bottle holder that form no part of the claimed design.

6. 发明公开

US20240148643A1 INTRACAMERAL SUSTAINED RELEASE THERAPEUTIC AGENT IMPLANTS 审中-公开
公开(公告)号：US20240148643A1
公开(公告)日：2024-05-09
申请号：US18236215
申请日：2023-08-21
申请人： Allergan, Inc.
发明人： Michael R. Robinson , James A. Burke , Rhett M. Schiffman , Alazar N. Ghebremeskel
IPC分类号： A61K9/00 , A61K9/16 , A61K31/5575 , A61K47/10 , A61K47/34 , A61L27/18 , A61L27/54 , A61L27/58
CPC分类号： A61K9/0051 , A61K9/0024 , A61K9/1647 , A61K31/5575 , A61K47/10 , A61K47/34 , A61L27/18 , A61L27/54 , A61L27/58
摘要： Described herein are intracameral implants including at least one therapeutic agent for treatment of at least one ocular condition. The implants described herein are not anchored to the ocular tissue, but rather are held in place by currents and gravity present in the anterior chamber of an eye. The implants are preferably polymeric, biodegradable and provide sustained release of at least one therapeutic agent to both the trabecular meshwork and associated ocular tissue and the fluids within the anterior chamber of an eye.

7. 发明公开

US20240108635A1 PROSTAMIDE-CONTAINING INTRAOCULAR IMPLANTS AND METHODS OF USE THEREOF 审中-公开
公开(公告)号：US20240108635A1
公开(公告)日：2024-04-04
申请号：US18231955
申请日：2023-08-09
申请人： Allergan, Inc.
发明人： Alazar N. Ghebremeskel , Michael R. Robinson
IPC分类号： A61K31/5575 , A61F9/00 , A61K9/00 , A61K9/16 , A61K31/165 , A61K47/10 , A61K47/34
CPC分类号： A61K31/5575 , A61F9/0017 , A61K9/0051 , A61K9/1647 , A61K31/165 , A61K47/10 , A61K47/34
摘要： Prostamide-containing intraocular implants that biodegrade in the eye and that are effective for reducing intraocular pressure in an eye for a sustained period. The implants generally contain a prostamide, such as bimatoprost, and at least three distinct biodegradable polymers selected from polylactide and poly(lactide-co-glycolide) polymers and are optimized for placement in and compatibility with the anterior chamber of the eye, particularly the anterior chamber angle. Methods for making and using the implants to reduce ocular hypertension and intraocular pressure in a patient are described.

8. 发明公开

US20240074894A1 DUAL CAP SYSTEM FOR CONTAINER-CLOSURES TO MAINTAIN TIP STERILITY DURING SHELF STORAGE 审中-公开
公开(公告)号：US20240074894A1
公开(公告)日：2024-03-07
申请号：US18345638
申请日：2023-06-30
申请人： Allergan, Inc.
发明人： Sai Shankar
IPC分类号： A61F9/00 , A61J1/14 , A61K31/205 , A61K31/407 , A61K31/496 , A61K31/498 , A61K31/5377 , A61K31/5575 , A61K31/573 , A61K38/13
CPC分类号： A61F9/0008 , A61J1/1475 , A61K31/205 , A61K31/407 , A61K31/496 , A61K31/498 , A61K31/5377 , A61K31/5575 , A61K31/573 , A61K38/13 , A61J1/18
摘要： A container-closure system includes a container configured to hold a therapeutic liquid and having a dispensing tip configured to dispense a dose of the therapeutic liquid. A vented cap is configured to fit over at least a portion of the container including the dispensing tip and having one or more vents that allow air to pass into and out of a cavity defined between the vented cap and the dispensing tip. A second cap is configured to fit over at least a portion of the vented cap. A tamper evident seal is coupled to the second cap and one or both of the container and the vented cap.

9. 发明公开

US20240050726A1 MICRONEEDLE ARRAY WITH ACTIVE INGREDIENT 审中-公开
公开(公告)号：US20240050726A1
公开(公告)日：2024-02-15
申请号：US18123292
申请日：2023-03-19
申请人： Allergan, Inc.
发明人： Futian LIU , Xiaojie YU , Lance E. STEWARD , Guang Wei LU , Patrick M. HUGHES , Seshadri NEERVANNAN
IPC分类号： A61M37/00 , A61K38/48 , A61K47/36 , A61P17/06 , A61P29/00 , A61K9/00 , A61K47/42
CPC分类号： A61M37/0015 , A61K38/4893 , A61K47/36 , A61P17/06 , A61P29/00 , A61K9/0021 , A61K47/42 , B29C33/42
摘要： Microneedle arrays for introducing an active ingredient through a skin surface of a subject can include a base layer, a plurality of microneedles projecting from the base layer, and an active ingredient. Each of the microneedles comprises an elongate body having a proximal portion and a distal portion, in which the proximal portion is attached to the base layer. Each of the microneedles comprises at least one dissolvable polymer. The active ingredient is incorporated in the elongate body, and the active ingredient is present only in the distal portion and at least internally in the distal portion.

10. 发明公开

US20240043518A1 HEAVY CHAIN ONLY ANTIBODIES TO PDGF 审中-公开
公开(公告)号：US20240043518A1
公开(公告)日：2024-02-08
申请号：US18322927
申请日：2023-05-24
申请人： Allergan, Inc.
发明人： Yanbin Liang , Daniel W. Gil
IPC分类号： C07K16/22 , A61K39/395
CPC分类号： C07K16/22 , A61K39/395 , C07K2317/565 , C07K2317/52 , C07K2317/92 , C07K2317/76 , C07K2317/64 , C07K2317/24 , C07K2317/522 , C07K2317/569 , A61K39/3955
摘要： Disclosed herein are monospecific HCAb antibodies with antigen-binding specificity to PDGF and bispecific antibodies with antigen-binding specificities to PDGF-2 and VEGF or to PDGF and ANG-2.

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