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1. 发明授权

US12050218B2 Mitochondrial protease OMA1 as a marker for breast cancer 有权
公开(公告)号：US12050218B2
公开(公告)日：2024-07-30
申请号：US16476961
申请日：2018-01-12
申请人： NUtech Ventures
发明人： Srivatsan Kidambi , Oleh Khalimonchuk
IPC分类号： G01N31/00 , C07K16/30 , C12N9/64 , G01N33/53 , G01N33/574
CPC分类号： G01N33/57415 , C07K16/3015 , C12N9/6489 , G01N33/57484 , G01N2333/8146
摘要： The use of mitochondrial protease OMA1 as a theranostic marker for breast cancer, tumor progression, metastatis and drug responsiveness is disclosed herein.

2. 发明授权

US12017527B2 All-terrain vehicle 有权
公开(公告)号：US12017527B2
公开(公告)日：2024-06-25
申请号：US18173114
申请日：2023-02-23
申请人： Textron Inc.
发明人： John C. Dunne, Jr. , Jon C. Charland , Jared Trauernicht , Hayden Barr , Eric Anderfaas
IPC分类号： B60K17/22 , B60K5/02 , B60K17/16 , B60K17/344 , B60K17/348 , B60R21/13 , B62D23/00 , B60K1/00 , B60K13/04 , B60K17/356
CPC分类号： B60K17/22 , B60K5/02 , B60K17/16 , B60K17/344 , B60K17/348 , B60R21/13 , B62D23/005 , B60K1/00 , B60K13/04 , B60K17/356 , B60Y2200/20
摘要： An all-terrain vehicle is provided comprising a chassis, four wheels and a passenger compartment that includes a passenger seating structure. The vehicle additionally comprises a drivetrain operatively connected to at least one of the wheels comprising at least one drive shaft and at least one torque transfer device. Furthermore the vehicle includes a prime mover that is mounted to the chassis entirely forward of a front edge of the seating structure and operatively connected to the drivetrain. The prime mover is structured and operable to provide motive force to at least one of the wheels.

3. 发明授权

US12005551B2 Adjustable pivot bolt for a sealed manhole clamp 有权
公开(公告)号：US12005551B2
公开(公告)日：2024-06-11
申请号：US16873236
申请日：2020-03-02
申请人： David E Sisk , Peter Kemp , Jason Husky
发明人： David E Sisk , Peter Kemp , Jason Husky
IPC分类号： B25B5/04 , B25B5/10 , B25B5/14 , B61D17/16 , B65D90/00
CPC分类号： B25B5/04 , B25B5/10 , B25B5/145 , B61D5/08 , B61D17/16
摘要： A sealed manhole clamp securing a manhole cover to a weld ring, including a lever assembly, the lever assembly having a lever arm and a cam, a pivot bolt, the pivot bolt having a cylindrical upper portion, and a lower portion, the lower bolt portion threadedly engages upwardly within the cylindrical upper portion of the pivot bolt, the cylindrical upper portion being pivotally pinned to the lever arm, the lower bolt portion being pivotally mounted to a seal ring, wherein since the lower bolt portion threadedly engages within the cylindrical upper portion, the entrance of any debris, dust, or moisture is prevented from entering the region of this threaded engagement of the pivot bolt components.

4. 外观设计

USD1025206S1 Nursing multi-skill training pad 有权
公开(公告)号：USD1025206S1
公开(公告)日：2024-04-30
申请号：US29766327
申请日：2021-01-14
申请人： Damon Coyle
设计人： Damon Coyle
摘要： FIG. 1 is an isometric top view of a nursing multi-skill training pad according to the design;
FIG. 2 is an isometric bottom view thereof;
FIG. 3 right side view thereof;
FIG. 4 is a left side view thereof;
FIG. 5 is a front view thereof;
FIG. 6 is a rear view thereof;
FIG. 7 is a top view thereof; and,
FIG. 8 is a bottom view thereof.
The broken lines immediately adjacent to the shaded areas depict the bounds of the claimed design, while all other broken lines are directed to environment. The broken lines form no part of the claimed design.

5. 外观设计

USD1017968S1 Hat design 有权
公开(公告)号：USD1017968S1
公开(公告)日：2024-03-19
申请号：US29887042
申请日：2023-03-16
申请人： Levi T. McPhee
设计人： Levi T. McPhee
摘要： FIG. 1 is a perspective view of an embodiment of the hat design.
FIG. 2 is a top plan view thereof.
FIG. 3 is a bottom plan view thereof.
FIG. 4 is a front elevation view thereof.
FIG. 5 is a rear elevation view thereof.
FIG. 6 is a left side elevation view thereof.
FIG. 7 is a right side elevation view thereof.
FIG. 8 is a perspective view of a second embodiment of the hat design.
FIG. 9 is a top plan view of the hat design of FIG. 8.
FIG. 10 is a bottom plan view of the hat design of FIG. 8.
FIG. 11 is a front elevation view of the hat design of FIG. 8.
FIG. 12 is a rear elevation view of the hat design of FIG. 8.
FIG. 13 is a left side elevation view of the hat design of FIG. 8; and,
FIG. 14 is a right side elevation view of the hat design of FIG. 8.
The broken lines depict features of the hat that form no part of the claimed design.

6. 发明授权

US11929644B2 Rotating electric machine having an improved annular cooling chamber 有权
公开(公告)号：US11929644B2
公开(公告)日：2024-03-12
申请号：US17425262
申请日：2020-02-25
申请人： NIDEC PSA EMOTORS
发明人： Ioan Deac , Juan Wang , Hussain Nouri , Guillaume Tardy
IPC分类号： H02K1/20 , H02K1/18 , H02K5/20
CPC分类号： H02K1/20 , H02K1/185 , H02K5/203
摘要： The rotating electric machine (1) having a housing comprising first (14) and second (15) clamp members and an inner face, a stator comprising a stator body (41) clamped between the first and second clamp members and having an outer face extending opposite the inner face together defining an annular cooling chamber (21) surrounding the stator body, the stator body comprising a longitudinal stack of stator sheets (410), each stator pack of which comprises an annular core having an outer circumference and at least two radially centrifugal protuberances projecting from the outer circumference of the annular core, in the annular cooling chamber, and diametrically opposite one another, the stator sheets of the longitudinal stack being identical and two adjacent stator sheet of the longitudinal stack being angularly offset from each other such that the respective protuberances thereof do not extend opposite one another.

7. 发明授权

US11903868B2 Assembly for treatment providing non-invasive controlled positioning and movement of a patient's jaw 有权
公开(公告)号：US11903868B2
公开(公告)日：2024-02-20
申请号：US18083052
申请日：2022-12-16
申请人： Gary B. Wiele
发明人： Gary B. Wiele
IPC分类号： A61F5/56
CPC分类号： A61F5/566
摘要： An oral treatment assembly providing a plurality of medical treatments of a patient that are non-invasive and in particular provides new methods for treating jaw related medical conditions of a patient through predetermined positioning and controlled or guided movement of a patient's mandible and therefore their mandibular condyles during use, wherein the assembly includes an upper and lower assembly each defining transition portions having a reverse cut angle that extends downward from the posterior forward to the anterior, and where each are configured to selectively engage to restrict the retrusion of the mandible relative to the maxilla and to position the mandible relative to the maxilla downward and in some embodiment slightly forward in a caregiver defined treatment position and having a caregiver defined treatment movement area thereabout. Since the reversed cut angle contains two vectors it also discourages involuntary dropping of the mandible relative to the maxilla.

8. 发明授权

US11857112B2 Heat exchanging liquid container 有权
公开(公告)号：US11857112B2
公开(公告)日：2024-01-02
申请号：US17257061
申请日：2019-07-31
申请人： THE CURATORS OF THE UNIVERSITY OF MISSOURI
发明人： Hongbin Ma
IPC分类号： A47J41/00 , A47G19/22 , C09K5/06
CPC分类号： A47J41/0044 , A47G19/2288 , A47J41/0011 , C09K5/066
摘要： A heat exchanging liquid container system comprising a main body; a phase change material (PCM) module disposable within the main body; a PCM disposed within the PCM module; a liquid reservoir defined by the main body and/or the PCM module configured to have liquid disposed therein having a first temperature; and a temperature conditioning channel formed along a wall of the PCM module and/or through the PCM module such that the temperature conditioning channel is in thermal contact with the PCM. The temperature conditioning channel configured to provide a flow path through which the liquid can flow to dispense the liquid from the liquid reservoir such that the liquid will be in thermal contact with the PCM while being dispensed. The PCM configured to exchange thermal energy with the liquid and thereby condition the liquid to be dispensed at a second temperature that is within a desired temperature range.

9. 发明授权

US11841098B2 Wireless connection safety break device 有权
公开(公告)号：US11841098B2
公开(公告)日：2023-12-12
申请号：US16873407
申请日：2020-04-08
申请人： Tim Schroeder , Arthur C. Fink
发明人： Tim Schroeder , Arthur C. Fink
IPC分类号： F16L29/00 , G08C17/02 , F16K15/00
CPC分类号： F16L29/00 , G08C17/02 , F16K15/00
摘要： A wireless communication safety break device is disclosed which has an upper safety break portion having a fuel inlet, an upper portion check valve, an upper portion communications device, an upper portion contact point or switch, and a lower safety break portion having a fuel outlet, a lower portion check valve, a lower portion contact point or switch, and a locator device.

10. 发明授权

US11839915B2 System and method for determining beam power level along an additive deposition path 有权
公开(公告)号：US11839915B2
公开(公告)日：2023-12-12
申请号：US17153650
申请日：2021-01-20
申请人： Product Innovation and Engineering L.L.C.
发明人： Todd Eugene Sparks
IPC分类号： B22F10/366 , B22F12/30 , B22F12/44 , B33Y30/00 , B22F10/85 , B22F12/50 , B33Y50/02 , B22F10/368
CPC分类号： B22F10/366 , B22F10/368 , B22F10/85 , B22F12/30 , B22F12/44 , B22F12/50 , B33Y30/00 , B33Y50/02
摘要： A laser power control method for additive manufacturing includes a pre-processing component and an intra-processing component. The pre-processing component creates in the system controller a machine code expressed additive-path-with-geometry-metadata that includes a path description. The path description represents the path of the beam source on the build and includes a geometry index for the build. The intra-processing component calculates required power for the beam at intervals and events on the beam path based upon the additive-path-with-geometry-metadata and calculations of the energy balance at the melt pool and the total energy for each point P(s) on the path.

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