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1. 发明授权

US07115709B1 Methods of staining target chromosomal DNA employing high complexity nucleic acid probes 失效
标题翻译：使用高度复杂的核酸探针染色靶染色体DNA的方法
公开(公告)号：US07115709B1
公开(公告)日：2006-10-03
申请号：US08487701
申请日：1995-06-07
申请人： Joe W. Gray , Daniel Pinkel , Ol'li-Pekka Kallioniemi , Anne Kallioniemi , Masaru Sakamoto
发明人： Joe W. Gray , Daniel Pinkel , Ol'li-Pekka Kallioniemi , Anne Kallioniemi , Masaru Sakamoto
IPC分类号： C07K17/00 , C12Q1/68
CPC分类号： C12Q1/6879 , C12Q1/6827 , C12Q1/6841 , C12Q1/6876 , C12Q1/6886 , C12Q2563/107 , C12Q2563/131 , C12Q2525/151
摘要： Methods and compositions for staining based upon nucleic acid sequence that employ nucleic acid probes are provided. Said methods produce staining patterns that can be tailored for specific cytogenetic analyses. Said probes are appropriate for in situ hybridization and stain both interphase and metaphase chromosomal material with reliable signals. The nucleic acid probes are typically of a complexity greater than 50 kb, the complexity depending upon the cytogenetic application. Methods and reagents are provided for the detection of genetic rearrangements. Probes and test kits are provided for use in detecting genetic rearrangements, particularly for use in tumor cytogenetics, in the detection of disease related loci, specifically cancer, such as chronic myelogenous leukemia (CML), retinoblastoma, ovarian and uterine cancers, and for biological dosimetry. Methods and reagents are described for cytogenetic research, for the differentiation of cytogenetically similar but genetically different diseases, and for many prognostic and diagnostic applications.
摘要翻译：提供了基于使用核酸探针的核酸序列进行染色的方法和组合物。所述方法产生可针对特定细胞遗传学分析进行定制的染色模式。所述探针适用于原位杂交并染色具有可靠信号的相间和中期染色体材料。核酸探针通常具有大于50kb的复杂度，其复杂性取决于细胞遗传学应用。提供方法和试剂用于检测遗传重排。探针和测试试剂盒用于检测遗传重排，特别是用于肿瘤细胞遗传学，用于检测疾病相关的基因座，特别是癌症，如慢性骨髓性白血病（CML），视网膜母细胞瘤，卵巢和子宫癌，以及生物学剂量测定描述了细胞遗传学研究的方法和试剂，用于细胞遗传学上相似但遗传上不同的疾病的分化，以及许多预后和诊断应用。

2. 发明授权

US07111848B2 Gasket and method of manufacturing the gasket 失效
标题翻译：垫片及垫片的制造方法
公开(公告)号：US07111848B2
公开(公告)日：2006-09-26
申请号：US10380518
申请日：2001-09-14
申请人： Kouichi Tachikawa , Hiroyuki Yunoki , Yutaka Kikuchi
发明人： Kouichi Tachikawa , Hiroyuki Yunoki , Yutaka Kikuchi
IPC分类号： A61M5/315 , F16J15/20
CPC分类号： B29C43/021 , A61M5/31513 , A61M2005/3131 , A61M2205/0222 , A61M2205/0238 , A61M2207/10 , B29C35/02 , B29C43/184 , B29C2043/023 , B29C2043/3615 , B29K2021/00 , B29L2031/7544
摘要： A gasket is capable of providing an excellent slidabiity and holding its sealability without applying lubricant and a gasket that can prevent a resin film from being peeled off of a gasket body and prevent the generation of a molding defect such as pinholes. The gasket can be installed slidably in a outer tube of a syringe, including a gasket body and a resin film formed of a material lower in coefficient of friction than a material of the gasket body, which covers at least an outer periphery of the gasket body, in which when a surface roughness of the resin film on the outer tube side is defined as Ra1 and a surface roughness of the resin film on the gasket body side is defined as Ra2, a relationship of 1.5 Ra1≦Ra2 is satisfied.
摘要翻译：垫圈能够提供优异的滑动性并保持其密封性而不施加润滑剂和垫圈，其可以防止树脂膜从垫圈主体剥离并防止产生诸如针孔的模制缺陷。衬垫可以可滑动地安装在注射器的外管中，包括垫圈体和树脂膜，所述树脂膜由比垫片主体的材料低的摩擦系数材料形成，该材料至少覆盖垫圈体的外周其中当外管侧的树脂膜的表面粗糙度定义为Ra 1时，并且衬垫主体侧的树脂膜的表面粗糙度定义为Ra 2 < / SUB>，满足1.5 Ra 1 <= RA 2 2 的关系。

3. 发明授权

US07074170B2 Method and apparatus for making cigarette filters with a centrally located flavored element 有权
公开(公告)号：US07074170B2
公开(公告)日：2006-07-11
申请号：US10397275
申请日：2003-03-27
申请人： Robert C. Lanier, Jr. , Steven M. Campbell , Stephen J. Bellamah
发明人： Robert C. Lanier, Jr. , Steven M. Campbell , Stephen J. Bellamah
IPC分类号： B31C13/00
CPC分类号： A24D3/022 , Y10S493/941
摘要： A filter making apparatus includes a positioning device having a passageway therethrough, with the passageway guiding a continuous flavor element such as a continuous strand of textile material from an inlet of the passageway to an outlet of the passageway. A liquid flavorant is introduced into the passageway at a desired flow rate and the strand of material carries the supplied liquid flavorant out of the positioning device at a rate substantially equal to the desired flow rate. A portion of the passageway can form a bath of the liquid flavorant supplied to the passageway through a separate inlet at approximately atmospheric pressure. A portion of the positioning device guides the continuous strand of material through the bath, or guides the strand to pass along the bottom of the passageway, and the saturated or partially saturated strand of material then exits from an outlet of the passageway to a point in the path of filter tow material that is being converged to form a filter rod.

4. 发明授权

US07031061B2 Diffusing film comprising transparent resin and scatterers 失效
公开(公告)号：US07031061B2
公开(公告)日：2006-04-18
申请号：US10767263
申请日：2004-01-30
申请人： Yoji Ito
发明人： Yoji Ito
IPC分类号： G02B13/20
CPC分类号： G02B5/0226 , G02B5/0278
摘要： A diffusing film comprises a transparent resin in which scatterers are dispersed. The difference between the refractive index of the transparent resin and that of the scatterers is in the range of 0.04 to 1.5. The scatterers are flat particles having sizes of 0.1 to 50 μm.

5. 发明授权

US07005234B2 Planographic printing plate precursor and planographic printing method 有权
公开(公告)号：US07005234B2
公开(公告)日：2006-02-28
申请号：US10101316
申请日：2002-03-20
申请人： Satoshi Hoshi , Keitaro Aoshima
发明人： Satoshi Hoshi , Keitaro Aoshima
IPC分类号： G03F7/038
CPC分类号： B41C1/1008 , B41C1/1016 , B41C2201/04 , B41C2210/04 , B41C2210/06 , B41C2210/22 , B41C2210/24 , B41N3/038 , Y10S430/145 , Y10S430/146
摘要： The present invention provides a planographic printing plate precursor comprising a photosensitive layer on a support, the photosensitive layer including an infrared absorbent, a radical polymerization initiator and a radical polymerizing compound, the photosensitive layer being recordable with irradiation with an infrared ray, and being at least one of soluble and dispersible in water.

6. 外观设计

USD514888S1 Bowl 有权
公开(公告)号：USD514888S1
公开(公告)日：2006-02-14
申请号：US29222664
申请日：2005-02-03
申请人： John Rocha
设计人： John Rocha

7. 发明授权

US06994138B2 Tire for two-wheeled vehicle 有权
标题翻译：轮胎为两轮车
公开(公告)号：US06994138B2
公开(公告)日：2006-02-07
申请号：US10978414
申请日：2004-11-02
申请人： Yann Chaylard
发明人： Yann Chaylard
IPC分类号： B60C9/22 , B60C3/04
CPC分类号： B60C9/2204 , B60C2009/2271 , B60C2200/10 , Y10T152/10774 , Y10T152/10783
摘要： The invention relates to a tire for a two-wheeled motorized vehicle and more particularly a motorcycle.Such a tire comprises at least one carcass-type reinforcement structure, formed of reinforcement elements forming with the circumferential direction an angle of between 65° and 90°, anchored on either side of the tire to a bead whose base is intended to be fitted on a rim seat, each bead being extended radially towards the outside by a sidewall, the sidewalls meeting up, radially towards the outside, with a tread whose Ht/Wt ratio is greater than 0.15, said carcass reinforcement being radially surmounted at least in the zone of the tread by a crown reinforcement formed of at least one layer of circumferential reinforcement elements. According to the invention, said circumferential reinforcement elements are distributed in the transverse direction with a variable pitch such that said pitch is smaller at the centre (crown) of the tread than at the edges of said layer and such that the value of the pitch in the transverse direction follows an increasing mathematical progression over at least part of the axial width of said layer.
摘要翻译：本发明涉及一种用于两轮电动车辆的轮胎，更具体地说涉及一种摩托车。

8. 植物专利

USPP16230P3 Cotoneaster plant named ‘Belka’ 有权
标题翻译：枸杞子植物“Belka”
公开(公告)号：USPP16230P3
公开(公告)日：2006-01-31
申请号：US10912158
申请日：2004-08-06
申请人： Véronique Bellenot-Kapusta , Alain Cadic
发明人： Véronique Bellenot-Kapusta , Alain Cadic
IPC分类号： A01H5/00
CPC分类号： A01H5/00
摘要： A new and distinct Cotoneaster dammeri cultivar is provided which unlike previously known cultivars displays very good tolerance to fire blight (Erwinia amylovora). The foliage is attractive dense medium green and is semi-glossy on the upper surface and dull and pubescent on the under surface. A creeping growth habit with erect branching is displayed. Good cold tolerance has been observed. The new cultivar is well suited for use as an improved attractive low-growing ornamental ground cover.
摘要翻译：提供了一种新的和独特的枸杞子品种，与以前知道的品种不同，显示出非常好的耐火性（欧文氏菌（Erwinia amylovora））。叶子是吸引人的密集的中等绿色，在上表面是半光泽的，在下表面上是钝的和短柔毛的。显示直立分支的爬行生长习性。观察到良好的耐寒性。新品种非常适合用作改良的有吸引力的低增长装饰性地面覆盖物。

9. 植物专利

USPP16203P3 Golden and burgundy variegated pigmy Barberry plant named ‘Goruzam’ 有权
标题翻译：金色和勃艮第杂色的野牛番茄植物名为“Goruzam”
公开(公告)号：USPP16203P3
公开(公告)日：2006-01-17
申请号：US10866821
申请日：2004-06-15
申请人： James W. Zampini
发明人： James W. Zampini
IPC分类号： A01H5/00
CPC分类号： A01H5/12
摘要： A new and distinct variety of Berberis thunbergii plant is provided that was the result of controlled breeding. A dwarf, generally compact, broad, and low-mounding growth habit is displayed. New foliage bears a bright red-purple coloration, and the mature foliage displays attractive variegation. The margins of the mature foliage are golden and the center is dark burgundy. A rapid growth rate between internodes of relatively short length is displayed. The plant is well suited for providing attractive ornamentation in the landscape.
摘要翻译：提供了一种新的和独特的小檗种类，这是受控育种的结果。显示出矮小的，一般紧凑的，宽阔的，低洼的生长习惯。新树叶呈红色紫红色，成熟的叶子显示有吸引力的杂色。成熟叶子的边缘是金色的，中心是黑色的勃艮第。显示长度相对较短的节间间的快速生长速度。该植物非常适合在景观中提供有吸引力的装饰。

10. 发明授权

US06987226B2 Occupant weight detecting apparatus 有权
公开(公告)号：US06987226B2
公开(公告)日：2006-01-17
申请号：US10396485
申请日：2003-03-26
申请人： Morio Sakai , Koji Aoki , Masaki Mori , Minoru Izawa , Yasunori Hasegawa , Takaaki Enomoto
发明人： Morio Sakai , Koji Aoki , Masaki Mori , Minoru Izawa , Yasunori Hasegawa , Takaaki Enomoto
IPC分类号： B60Q1/00 , G01G23/01
CPC分类号： B60R21/01516 , B60R21/0152 , B60R21/01556 , G01G19/4142
摘要： An occupant weight detecting apparatus for detecting an occupant weight on a seat includes a load sensor mounted on the seat to detect a load on the seat and output a load signal. A detected load value is calculated periodically based on the load signal and an average is calculated based on the detected load values calculated during a period in which the detected load value is less than a first predetermined. The average of the detected load values is set to a zero point, and the occupant weight is detected based on the detected load value and the zero point when the detected load value exceeds a second predetermined value.

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