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1. 发明授权

US09585929B2 Coix seed oil containing 13 glycerides, and pharmaceutical preparation and use thereof 有权
标题翻译：含有13种甘油酯的Co ix籽油及其药物制剂及其用途
公开(公告)号：US09585929B2
公开(公告)日：2017-03-07
申请号：US14733079
申请日：2015-06-08
申请人： ZHEJIANG KANGLAITE GROUP CO., LTD.
发明人： Dapeng Li
IPC分类号： A01N37/02 , A61K36/8994 , A61K31/232 , A61K31/231
CPC分类号： A61K36/8994 , A61K31/231 , A61K31/232 , A61K2236/00
摘要： The present invention relates to Coix seed oil extracted from Semen Coicis, pharmaceutical preparations thereof, and the use thereof in the treatment of tumors and inflammation. Specifically, the Coix seed oil contains 5 diglyceride and 8 triglyceride ingredients in the following mass percentages: 1,3-diolein 0.40-0.58%, 1-linolein-3-olein 0.91-1.31%, 1,2-diolein 0.24-0.35%, 1-olein-2-linolein 0.66-0.95%, 1,2-dilinolein 0.33-0.47%, trilinolein 4.87-6.99%, 1-olein-2,3-dilinolein 13.00-18.69%, 1-palmitin-2,3-dilinolein 5.25-7.54%, 1,3-diolein-2-linolein 13.23-19.02%, 1-palmitin-2-linolein-3-olein 10.26-14.75%, 1,3-dipalmitin-2-linolein 2.28-3.28%, triolein 14.44-20.76% and 1-palmitin-2,3-diolein 8.06-11.58%.
摘要翻译：本发明涉及从Semen Coicis提取的Co ix籽油，其药物制剂及其在治疗肿瘤和炎症中的用途。具体来说，蓖麻籽油含有以下质量百分比的5种甘油二酯和8种甘油三酯成分：1,3-二油烯0.40-0.58％，1-亚油酸烯丙酯-3-油烯0.91-1.31％，1,2-二油烯0.24-0.35％，1-油烯-2-亚油酸烯0.66-0.95％，1,2-二油烯醇0.33-0.47％，三烯醇钠4.87-6.99％，1-油烯-2,3-二油烯醇13.00-18.69％，1-棕榈素-23 二烯醇含量5.25-7.54％，1,3-二油烯-2-亚油酸烯醇13.23-19.02％，1-棕榈素-2-亚油酸烯丙酯-3-油精10.26-14.75％，1,3-二棕榈精-2-亚油酸烯醇2.28-3.28％，三油精14.44-20.76％和1-棕榈素-2,3-二油烯8.06-11.58％。

2. 发明授权

US10596218B2 Coix seed oil containing 16 glycerides, and pharmaceutical preparation and use thereof 有权
公开(公告)号：US10596218B2
公开(公告)日：2020-03-24
申请号：US15324890
申请日：2015-07-17
申请人： ZHEJIANG KANGLAITE GROUP CO., LTD.
发明人： Dapeng Li
IPC分类号： A61K36/8994 , A61K9/10 , A61K9/48 , A61K9/14 , A61K9/08 , A61K31/21 , A61K9/20 , A61K9/127 , A61K9/00 , A61K31/231 , A61K31/232 , A61K47/10 , A61K47/24
摘要： The present invention relates to Coix seed oil extracted from Semen Coicis, pharmaceutical preparations thereof, and the use thereof in the treatment of tumors. Specifically, the Coix seed oil contains 5 diglyceride and 11 triglyceride ingredients in the following mass percentages: 1,3-diolein 0.40-0.58%, 1-linolein-3-olein 0.91-1.31%, 1,2-diolein 0.24-0.35%, 1-olein-2-linolein 0.66-0.95%, 1,2-dilinolein 0.33-0.47%, trilinolein 4.87-6.99%, 1-olein-2,3-dilinolein 13.00-18.69%, 1-palmitin-2,3-dilinolein 5.25-7.54%, 1,3-diolein-2-linolein 13.23-19.02%, 1-palmitin-2-linolein-3-olein 10.26-14.75%, 1,3-dipalmitin-2-linolein 2.28-3.28%, triolein 14.44-20.76%, 1-palmitin-2,3-diolein 8.06-11.58%, 1-olein-2-linolein-3-stearin 1.37-1.97%, 1,3-dipalmitin-2-olein 1.52-2.19% and 1,2-diolein-3-stearin 1.29-1.86%.

3. 发明授权

US09585858B2 Pharmaceutical composition containing 13 triglycerides, and preparations and use thereof 有权
标题翻译：含有13种甘油三酸酯的药物组合物及其制备方法及用途
公开(公告)号：US09585858B2
公开(公告)日：2017-03-07
申请号：US14733098
申请日：2015-06-08
申请人： ZHEJIANG KANGLAITE GROUP CO., LTD.
发明人： Dapeng Li
IPC分类号： A61K36/8994 , A61K8/97 , A61K31/231 , A61K45/06 , A61K9/00 , A61K9/48 , A61K31/23 , A61K35/17 , A61K47/10 , A61K47/24
CPC分类号： A61K31/231 , A61K9/0019 , A61K9/4858 , A61K31/23 , A61K35/17 , A61K45/06 , A61K47/10 , A61K47/24 , A61K2300/00
摘要： The present invention relates to a pharmaceutical composition containing 13 compounds: 1,3-diolein, 1-linolein-3-olein, 1,2-diolein, 1-olein-2-linolein, 1,2-dilinolein, trilinolein, 1-olein-2,3-dilinolein, 1-palmitin-2,3-dilinolein, 1,3-diolein-2-linolein, 1-palmitin-2-linolein-3-olein, 1,3-dipalmitin-2-linolein, triolein and 1-palmitin-2,3-diolein. The invention also relates to pharmaceutical preparations of this composition and the use thereof in the treatment of tumors and in the immuno-enhancement.
摘要翻译：本发明涉及含有13种化合物的1,3-二油烯，1-亚油酸烯丙酯-3-油精，1,2-二油精，1-油烯-2-亚油醇精，1,2-二油烯醇，三烯醇，1- 油精-2,3-二油烯醇，1-棕榈素-2,3-二烯丙醇，1,3-二油烯-2亚油酸烯醇，1-棕榈素-2-亚油烯-3-油精，1,3-二棕榈精-2-亚油醇烯，三油精和1-棕榈素-2,3-二油烯。本发明还涉及该组合物的药物制剂及其在治疗肿瘤和免疫增强中的用途。

4. 发明授权

US10314878B2 Coix seed oil containing 11 triglycerides, and pharmaceutical preparation and use thereof 有权
公开(公告)号：US10314878B2
公开(公告)日：2019-06-11
申请号：US15324873
申请日：2015-07-17
申请人： ZHEJIANG KANGLAITE GROUP CO., LTD.
发明人： Dapeng Li
IPC分类号： A61K8/92 , A61K36/8994 , A61K9/08 , A61K9/10 , A61K9/127 , A61K9/14 , A61K9/20 , A61K9/48 , A61K31/21 , A61K9/00 , A61K31/23 , A61K31/231 , A61K47/10 , A61K47/24 , C07C69/30 , C07C69/58 , C07C69/587 , C11B1/10 , C11B3/00 , A61K47/14 , A61K47/44
摘要： The present invention relates to Coix seed oil extracted from Semen Coicis, pharmaceutical preparations thereof, and the use thereof in the treatment of tumors. Specifically, the Coix seed oil contains 11 triglyceride ingredients in the following mass percentages: trilinolein 4.87-6.99%, 1-olein-2,3-dilinolein 13.00-18.69%, 1-palmitin-2,3-dilinolein 5.25-7.54%, 1,3-diolein-2-linolein 13.23-19.02%, 1-palmitin-2-linolein-3-olein 10.26-14.75%, 1,3-dipalmitin-2-linolein 2.28-3.28%, triolein 14.44-20.76% and 1-palmitin-2,3-diolein 8.06-11.58%, 1-olein-2-linolein-3-stearin 1.37-1.97%, 1,3-dipalmitin-2-olein 1.52-2.19% and 1,2-diolein-3-stearin 1.29-1.86%.

5. 发明授权

US09855310B2 Coix seed oil containing 8 triglycerides, and pharmaceutical preparation and use thereof 有权
公开(公告)号：US09855310B2
公开(公告)日：2018-01-02
申请号：US14732797
申请日：2015-06-08
申请人： ZHEJIANG KANGLAITE GROUP CO., LTD.
发明人： Dapeng Li
IPC分类号： A23D9/00 , A61K36/8994 , A61K31/232
CPC分类号： A61K36/8994 , A61K31/232 , A61K2236/00
摘要： The present invention relates to Coix seed oil extracted from Semen Coicis, pharmaceutical preparations thereof, and the use thereof in the treatment of tumors and inflammation. Specifically, the Coix seed oil contains 8 triglyceride ingredients in the following mass percentages: trilinolein 4.87-6.99%, 1-olein-2,3-dilinolein 13.00-18.69%, 1-palmitin-2,3-dilinolein 5.25-7.54%, 1,3-diolein-2-linolein 13.23-19.02%, 1-palmitin-2-linolein-3-olein 10.26-14.75%, 1,3-dipalmitin-2-linolein 2.28-3.28%, triolein 14.44-20.76%, and 1-palmitin-2,3-diolein 8.06-11.58%.

6. 发明申请

US20170209517A1 COIX SEED OIL CONTAINING 11 TRIGLYCERIDES, AND PHARMACEUTICAL PREPARATION AND USE THEREOF 审中-公开
公开(公告)号：US20170209517A1
公开(公告)日：2017-07-27
申请号：US15324873
申请日：2015-07-17
申请人： ZHEJIANG KANGLAITE GROUP CO., LTD.
发明人： DAPENG LI
IPC分类号： A61K36/8994 , C11B3/00 , C07C69/587 , C07C69/58 , A61K9/48 , A61K31/231 , A61K31/23 , A61K47/24 , A61K47/10 , A61K9/00 , C11B1/10 , C07C69/30
CPC分类号： A61K36/8994 , A61K9/0019 , A61K9/08 , A61K9/10 , A61K9/127 , A61K9/14 , A61K9/20 , A61K9/48 , A61K9/4825 , A61K9/4833 , A61K9/4858 , A61K31/21 , A61K31/23 , A61K31/231 , A61K47/10 , A61K47/14 , A61K47/24 , A61K47/44 , A61K2236/35 , A61K2236/37 , C07C69/30 , C07C69/58 , C07C69/587 , C11B1/104 , C11B3/001 , C11B3/006 , C11B3/008
摘要： The present invention relates to Coix seed oil extracted from Semen Coicis, pharmaceutical preparations thereof, and the use thereof in the treatment of tumors. Specifically, the Coix seed oil contains 11 triglyceride ingredients in the following mass percentages: trilinolein 4.87-6.99%, 1-olein-2,3-dilinolein 13.00-18.69%, 1-palmitin-2,3-dilinolein 5.25-7.54%, 1,3-diolein-2-linolein 13.23-19.02%, 1-palmitin-2-linolein-3-olein 10.26-14.75%, 1,3-dipalmitin-2-linolein 2.28-3.28%, triolein 14.44-20.76% and 1-palmitin-2,3-diolein 8.06-11.58%, 1-olein-2-linolein-3-stearin 1.37-1.97%, 1,3-dipalmitin-2-olein 1.52-2.19% and 1,2-diolein-3-stearin 1.29-1.86%.

7. 发明申请

US20160015769A1 COIX SEED OIL CONTAINING 13 GLYCERIDES, AND PHARMACEUTICAL PREPARATION AND USE THEREOF 有权
标题翻译：含有13种甘油的混合种子油，以及药物制备及其用途
公开(公告)号：US20160015769A1
公开(公告)日：2016-01-21
申请号：US14733079
申请日：2015-06-08
申请人： DAPENG LI
发明人： DAPENG LI
IPC分类号： A61K36/8994 , A61K31/231 , A61K31/232
CPC分类号： A61K36/8994 , A61K31/231 , A61K31/232 , A61K2236/00
摘要： The present invention relates to Coix seed oil extracted from Semen Coicis, pharmaceutical preparations thereof, and the use thereof in the treatment of tumors and inflammation. Specifically, the Coix seed oil contains 5 diglyceride and 8 triglyceride ingredients in the following mass percentages: 1,3-diolein 0.40-0.58%, 1-linolein-3-olein 0.91-1.31%, 1,2-diolein 0.24-0.35%, 1-olein-2-linolein 0.66-0.95%, 1,2-dilinolein 0.33-0.47%, trilinolein 4.87-6.99%, 1-olein-2,3-dilinolein 13.00-18.69%, 1-palmitin-2,3-dilinolein 5.25-7.54%, 1,3-diolein-2-linolein 13.23-19.02%, 1-palmitin-2-linolein-3-olein 10.26-14.75%, 1,3-dipalmitin-2-linolein 2.28-3.28%, triolein 14.44-20.76% and 1-palmitin-2,3-diolein 8.06-11.58%.
摘要翻译：本发明涉及从Semen Coicis提取的Co ix籽油，其药物制剂及其在治疗肿瘤和炎症中的用途。具体来说，蓖麻籽油含有以下质量百分比的5种甘油二酯和8种甘油三酯成分：1,3-二油烯0.40-0.58％，1-亚油酸烯丙酯-3-油烯0.91-1.31％，1,2-二油烯0.24-0.35％，1-油烯-2-亚油酸烯0.66-0.95％，1,2-二油烯醇0.33-0.47％，三烯醇钠4.87-6.99％，1-油烯-2,3-二油烯醇13.00-18.69％，1-棕榈素-23 - 二油烯醇5.25-7.54％，1,3-二油烯-2-亚油酸烯醇13.23-19.02％，1-棕榈素-2-亚油酸烯丙酯-3-油精10.26-14.75％，1,3-二棕榈精-2-亚油酸烯醇2.28-3.28％，三油精14.44-20.76％和1-棕榈素-2,3-二油烯8.06-11.58％。

8. 发明申请

US20160015671A1 PHARMACEUTICAL COMPOSITION CONTAINING 8 TRIGLYCERIDES, AND PREPARATIONS AND USE THEREOF 有权
标题翻译：含有8种三聚物的药物组合物及其制备及其用途
公开(公告)号：US20160015671A1
公开(公告)日：2016-01-21
申请号：US14733050
申请日：2015-06-08
申请人： DAPENG LI
发明人： DAPENG LI
IPC分类号： A61K31/231 , A61K9/48 , A61K45/06 , A61K9/00
CPC分类号： A61K31/231 , A61K9/0019 , A61K9/4833 , A61K9/4858 , A61K9/4866 , A61K31/23 , A61K35/00 , A61K45/06 , A61K47/10 , A61K47/24 , A61K2300/00
摘要： The present invention relates to a pharmaceutical composition containing 8 compounds: trilinolein, 1-olein-2,3-dilinolein, 1-palmitin-2,3-dilinolein, 1,3-diolein-2-linolein, 1-palmitin-2-linolein-3-olein, 1,3-dipalmitin-2-linolein, triolein and 1-palmitin-2,3-diolein. The invention also relates to pharmaceutical preparations of this composition and the use thereof in the treatment of tumors and in the immuno-enhancement.
摘要翻译：本发明涉及一种含有8种化合物的药物组合物：三烯醇钠，1-油精-2,3-二烯丙醇钠，1-棕榈素-2,3-二烯丙醇钠，1,3-二油烯-2-亚油酸烯醇，1-棕榈素-2- 亚油酸烯丙酯-3-油精，1,3-二棕榈酸二烯丙酯，三油精和1-棕榈素-2,3-二油烯。本发明还涉及该组合物的药物制剂及其在治疗肿瘤和免疫增强中的用途。

9. 发明授权

US09884037B2 Pharmaceutical composition containing 8 triglycerides, and preparations and use thereof 有权
公开(公告)号：US09884037B2
公开(公告)日：2018-02-06
申请号：US14733050
申请日：2015-06-08
申请人： ZHEJIANG KANGLAITE GROUP CO., LTD.
发明人： Dapeng Li
IPC分类号： A61K9/00 , A61K9/48 , A61K31/231 , A61K45/06 , A61K31/23 , A61K35/00
CPC分类号： A61K31/231 , A61K9/0019 , A61K9/4833 , A61K9/4858 , A61K9/4866 , A61K31/23 , A61K35/00 , A61K45/06 , A61K47/10 , A61K47/24 , A61K2300/00
摘要： The present invention relates to a pharmaceutical composition containing 8 compounds: trilinolein, 1-olein-2,3-dilinolein, 1-palmitin-2,3-dilinolein, 1,3-diolein-2-linolein, 1-palmitin-2-linolein-3-olein, 1,3-dipalmitin-2-linolein, triolein and 1-palmitin-2,3-diolein. The invention also relates to pharmaceutical preparations of this composition and the use thereof in the treatment of tumors and in the immuno-enhancement.

10. 发明申请

US20170209518A1 COIX SEED OIL CONTAINING 16 GLYCERIDES, AND PHARMACEUTICAL PREPARATION AND USE THEREOF 审中-公开
公开(公告)号：US20170209518A1
公开(公告)日：2017-07-27
申请号：US15324890
申请日：2015-07-17
申请人： ZHEJIANG KANGLAITE GROUP CO., LTD.
发明人： Dapeng LI
IPC分类号： A61K36/8994 , A61K31/232 , A61K9/48 , A61K47/24 , A61K47/10 , A61K9/10 , A61K31/231 , A61K9/00
摘要： The present invention relates to Coix seed oil extracted from Semen Coicis, pharmaceutical preparations thereof, and the use thereof in the treatment of tumors. Specifically, the Coix seed oil contains 5 diglyceride and 11 triglyceride ingredients in the following mass percentages: 1,3-diolein 0.40-0.58%, 1-linolein-3-olein 0.91-1.31%, 1,2-diolein 0.24-0.35%, 1-olein-2-linolein 0.66-0.95%, 1,2-dilinolein 0.33-0.47%, trilinolein 4.87-6.99%, 1-olein-2,3-dilinolein 13.00-18.69%, 1-palmitin-2,3-dilinolein 5.25-7.54%, 1,3-diolein-2-linolein 13.23-19.02%, 1-palmitin-2-linolein-3-olein 10.26-14.75%, 1,3-dipalmitin-2-linolein 2.28-3.28%, triolein 14.44-20.76%, 1-palmitin-2,3-diolein 8.06-11.58%, 1-olein-2-linolein-3-stearin 1.37-1.97%, 1,3-dipalmitin-2-olein 1.52-2.19% and 1,2-diolein-3-stearin 1.29-1.86%.

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