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1. 发明申请

US20040186560A1 Stent for bifurcated vessels 审中-公开
标题翻译：支架用于分叉血管
公开(公告)号：US20040186560A1
公开(公告)日：2004-09-23
申请号：US10738913
申请日：2003-12-16
申请人： TBD
发明人： Eckhard Alt
IPC分类号： A61F002/06
CPC分类号： A61L31/18 , A61F2/91 , A61F2/915 , A61F2002/91541 , A61F2002/91558 , A61F2310/00598 , A61L31/022 , A61L31/088
摘要： A stent is adapted to be implanted in a side branch at a bifurcation from a main blood vessel in a patient's body, wherein the bifurcation from the main vessel is skewed, the stent having open ends, of which one is angled at a skew to the longitudinal axis of the stent to match the angulation of the side branch, whereby to afford substantially complete coverage of the inner wall of the side branch at the bifurcation, when the stent is implanted. The angle of the skew is about 45null, which gives the stent a short side and a long side connected together in a plane along the wall of the stent at that end end; and the other end of the stent is at a right angle to the longitudinal axis of the stent. At least one of the short side and the long side has a viewable marker to facilitate proper orientation of the stent during implant thereof. A drug-eluting coating is provided on the surface of the stent to inhibit restenosis of the side branch when the stent is implanted therein.
摘要翻译：支架适于从患者体内的主血管以分叉方式植入在侧支中，其中来自主血管的分叉是偏斜的，所述支架具有开口端，其中一个与所述主支管的歪斜成角度支架的纵向轴线以匹配侧分支的角度，从而当植入支架时，在分叉处提供基本上完全覆盖侧支的内壁。歪斜角度约为45°，这使得支架在短端和长边在连接在该端部的支架壁的平面内连接在一起; 并且支架的另一端与支架的纵向轴线成直角。短侧和长边中的至少一个具有可视标记，以便于在其植入期间支架的适当取向。当支架植入时，在支架的表面上设置药物洗脱涂层以抑制侧支的再狭窄。

2. 发明申请

US20070234211A1 Content transformation engine 审中-公开
标题翻译：内容转换引擎
公开(公告)号：US20070234211A1
公开(公告)日：2007-10-04
申请号：US11397076
申请日：2006-04-04
申请人： Bruce Henderson
发明人： Bruce Henderson
IPC分类号： G06F3/00
CPC分类号： G06Q10/10 , G06F16/972
摘要： A system for accumulating and presenting data in web-based content, the system comprising a plurality of silos each having raw data, a plurality of feedlets that transforms the raw data of the plurality of silos into a plurality of high value data feeds, and at least one fuselet for receiving the plurality of high value data feeds to generate a complex composite data feed, wherein the complex composite data feed is in a web-accessible format and represents a fusion of the plurality of high value data feeds.
摘要翻译：一种用于在基于web的内容中累积和呈现数据的系统，所述系统包括多个具有原始数据的仓库，多个饲料，其将所述多个筒仓的原始数据转换成多个高价值数据馈送，并且在用于接收所述多个高价值数据馈送以生成复合复合数据馈送的至少一个熔丝，其中所述复合复合数据馈送是网络可访问格式，并且表示所述多个高价值数据馈送的融合。

3. 发明申请

US20100004313A1 Modified Poloxamers for Gene Expression and Associated Methods 审中-公开
标题翻译：用于基因表达和相关方法的改良的泊洛沙姆
公开(公告)号：US20100004313A1
公开(公告)日：2010-01-07
申请号：US12395240
申请日：2009-02-27
申请人： Gregory Slobodkin , Majed Matar , Brian Jeffery Sparks , Jason Fewell , Khursheed Anwer
发明人： Gregory Slobodkin , Majed Matar , Brian Jeffery Sparks , Jason Fewell , Khursheed Anwer
IPC分类号： A61K48/00 , C08G65/00
CPC分类号： C08G65/329 , A61K9/0019 , A61K47/34
摘要： Nucleotide delivery polymers, compositions, and associated methods for the enhancement of gene delivery and expression in solid tissues are provided. In one aspect, for example, a nucleotide delivery polymer may include a poloxamer backbone having a metal chelator covalently coupled to at least one terminal end of the poloxamer backbone. In another aspect, the nucleotide expression polymer has a metal chelator coupled to at least two terminal ends of the poloxamer backbone.
摘要翻译：提供了用于增强固体组织中基因递送和表达的核苷酸递送聚合物，组合物和相关方法。在一个方面，例如，核苷酸递送聚合物可以包括具有与泊洛沙姆主链的至少一个末端共价连接的金属螯合剂的泊洛沙姆骨架。另一方面，核苷酸表达聚合物具有与泊洛沙姆主链的至少两个末端偶联的金属螯合剂。

4. 发明授权

US10440548B2 mPERS with internal conversion of GPS 有权
公开(公告)号：US10440548B2
公开(公告)日：2019-10-08
申请号：US15801907
申请日：2017-11-02
申请人： David Tropper
发明人： David Tropper
IPC分类号： H04W4/90 , H04M3/51 , H04W76/50
摘要： A unit transmits a call initiate signal over a communication network in response to the switch moving from the inactive position to the active position to establish a call with a 911 emergency service operator directly and enable voice communication. The unit is equipped to send a message indicative of ascertained location information of the unit to the 911 emergency service operator at an end of the established call. The unit contacts remote source to ascertain the location information and form the message. The unit maintains establishment of the call at least until the message is sent to the 911 emergency service operator. The unit itself lacks any GPS tracking module.

5. 发明申请

US20070037804A1 Imidazolone phenylalanine derivatives 失效
标题翻译：咪唑啉酮苯丙氨酸衍生物
公开(公告)号：US20070037804A1
公开(公告)日：2007-02-15
申请号：US11438659
申请日：2006-05-22
申请人： Frank Stappenbeck , Andrei Konradi , Jacek Jagodzinski , Christopher Semko , Ying-zi Xu , Jenifer Smith , Kassandra Rossiter
发明人： Frank Stappenbeck , Andrei Konradi , Jacek Jagodzinski , Christopher Semko , Ying-zi Xu , Jenifer Smith , Kassandra Rossiter
IPC分类号： A61K31/5377 , A61K31/496 , A61K31/4745 , A61K31/427 , A61K31/4184 , A61K31/423 , C07D471/02
CPC分类号： C07D471/04
摘要： Disclosed are compounds of the formula: and the pharmaceutically acceptable salts thereof wherein the variables A, n, R5, R21—R24 and Q are defined herein. These compounds bind VLA-4. Certain of these compound also inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. Such compounds are useful in the treatment of inflammatory diseases in a mammalian patient, e.g., human, such as asthma, Alzheimer's disease, atherosclerosis, AIDS dementia, diabetes, inflammatory bowel disease, rheumatoid arthritis, tissue transplantation, tumor metastasis and myocardial ischemia. The compounds can also be administered for the treatment of inflammatory brain diseases such as multiple sclerosis.
摘要翻译：公开了下式的化合物及其药学上可接受的盐，其中变量A，n，R 5，R 21和R 24和 Q在本文中定义。这些化合物结合VLA-4。这些化合物中的某些也抑制白细胞粘附，特别是由VLA-4介导的白细胞粘附。这样的化合物可用于治疗哺乳动物患者，例如人类例如哮喘，阿尔茨海默氏病，动脉粥样硬化，艾滋病痴呆，糖尿病，炎性肠病，类风湿性关节炎，组织移植，肿瘤转移和心肌缺血等炎性疾病。化合物也可以用于治疗炎性脑疾病如多发性硬化症。

6. 发明授权

US11388574B2 Methods and apparatus for providing access to emergency service providers 有权
公开(公告)号：US11388574B2
公开(公告)日：2022-07-12
申请号：US16269388
申请日：2019-02-06
申请人： TBD Safety, LLC
发明人： Hing-Tack Chen
IPC分类号： H04W4/90 , H04M1/72412 , H04M1/72418 , H04M1/72457 , H04M1/675 , H04M1/2745
摘要： A method and apparatus of communication via a hand held device that includes receiving an indication at the device to initiate an emergency call via a wireless network; determining whether the device is configured with a subscriber identity module (SIM) card, wherein the SIM card includes a plurality of numbers; and sequentially calling the plurality of numbers stored on the SIM card based on the determination that the device is configured with the SIM card. Further, the method and apparatus include detecting an emergency indication; connecting to a wireless network; and establishing a communication with one or more emergency service providers based at least in part on detecting the emergency indication, wherein the communication is established via the wireless network.

7. 发明授权

US11044595B2 Flip phone with direct access to emergency service providers 有权
公开(公告)号：US11044595B2
公开(公告)日：2021-06-22
申请号：US16596221
申请日：2019-10-08
申请人： TBD Safety, LLC
发明人： Brian McFadden , Timothy Cabrera , Hing-Tack Chen , David Tropper
IPC分类号： H04W4/90 , H04M1/675 , H04M1/2745 , H04M1/72412 , H04M1/72418 , H04M1/72457
摘要： A method and apparatus of communication via a hand held device that includes receiving an indication at the device to initiate an emergency call via a wireless network; determining whether the device is configured with a subscriber identity module (SIM) card, wherein the SIM card includes a plurality of numbers; and sequentially calling the plurality of numbers stored on the SIM card based on the determination that the device is configured with the SIM card. Further, the method and apparatus include detecting an emergency indication; connecting to a wireless network; and establishing a communication with one or more emergency service providers based at least in part on detecting the emergency indication, wherein the communication is established via the wireless network.

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