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1. 发明授权

US07494950B2 Bone cement compositions having fiber-reinforcement and/or increased flowability 有权
标题翻译：骨水泥组合物具有纤维增强和/或增加的流动性
公开(公告)号：US07494950B2
公开(公告)日：2009-02-24
申请号：US10936188
申请日：2004-09-07
申请人： Bryan Monro Armitage , Ira Ison , Mark Fulmer , Sean Kerr , Michael Lehmicke , Patrick Leamy , William Schiffer
发明人： Bryan Monro Armitage , Ira Ison , Mark Fulmer , Sean Kerr , Michael Lehmicke , Patrick Leamy , William Schiffer
IPC分类号： A61F2/28
CPC分类号： A61K31/74 , A61K33/06 , A61K33/42 , A61L24/001 , A61L24/0063 , A61L24/0084 , A61L27/425 , A61L27/46 , A61L27/50 , A61K2300/00
摘要： The present invention relates in general to implantable compositions, and method for preparing same, containing a calcium salt-containing component, optionally demineralized bone, a plurality of discrete fibers, optionally a flow additive, and optionally continuous reinforcing fibers or an array of organized fibers in the form of mesh. Advantageously, the discrete fibers have a specific aspect ratio (length/diameter) from about 50:1 to about 1000:1. The addition of a small amount of discrete fibers and/or the continuous reinforcing fibers or fiber mesh can cause drastic increases in certain mechanical properties including flexural strength, flexural toughness, and/or screw pullout strength.
摘要翻译：本发明一般涉及可植入组合物及其制备方法，其含有钙盐组分，任选的软化骨，多个离散纤维，任选的流动添加剂，以及可选地连续的增强纤维或有组织纤维阵列以网格的形式。有利地，离散纤维具有约50:1至约1000:1的特定纵横比（长度/直径）。添加少量离散纤维和/或连续增强纤维或纤维网可导致某些机械性能的急剧增加，包括弯曲强度，弯曲韧性和/或螺纹拔出强度。

2. 发明授权

US07481827B2 Linking transconnector for coupling spinal rods 有权
标题翻译：用于连接脊柱杆的连接横贯连接器
公开(公告)号：US07481827B2
公开(公告)日：2009-01-27
申请号：US10684351
申请日：2003-10-09
申请人： Christopher J. Ryan , Thomas R. Keyer , Martin Walther
发明人： Christopher J. Ryan , Thomas R. Keyer , Martin Walther
IPC分类号： A61B17/56
CPC分类号： A61B17/7049 , Y10T403/32032
摘要： A Linking Transconnector is disclosed for coupling a first longitudinal spinal rod to a second longitudinal spinal rod. The Linking Transconnector generally includes a pair of hook engaging members for engaging the longitudinal spinal rods, a lateral rod for spanning a distance between the hook engaging members, and a locking element which interconnects the hook engaging members with the lateral rod. The locking element being configured to allow for multiple degrees of adjustment to permit the Linking Transconnector to accommodate for varying spinal rod alignments. The locking element also permits the location of the lateral rod to be fixed relative to the hook engaging members once the desired position of the lateral rod with respect to the longitudinal spinal rods has been achieved. The locking element may also be able to fix the position of the lateral rod with respect to the hook engaging members by a force applied to the locking element.
摘要翻译：公开了一种用于将第一纵向脊柱杆联接到第二纵向脊柱杆的连接横向连接器。连接横连接器通常包括一对用于接合纵向脊柱杆的钩接合构件，用于跨越钩接合构件之间的距离的横向杆和将钩接合构件与侧杆互连的锁定元件。锁定元件被配置为允许多个度的调整，以允许连接横连接器适应于变化的脊柱杆对准。一旦横向杆相对于纵向脊柱杆的期望位置已经实现，锁定元件还允许相对于钩接合构件固定横向杆的位置。锁定元件还可以通过施加到锁定元件的力来固定侧向杆相对于钩接合构件的位置。

3. 发明授权

US07481815B2 Coplanar X-ray guided aiming arm for locking of intramedullary nails 有权
标题翻译：用于锁定髓内钉的共平面X射线引导瞄准臂
公开(公告)号：US07481815B2
公开(公告)日：2009-01-27
申请号：US10947155
申请日：2004-09-23
申请人： Alberto Angel Fernandez
发明人： Alberto Angel Fernandez
IPC分类号： A61B17/58
CPC分类号： A61B17/1725 , A61B17/1703 , A61B90/39 , A61B2017/00831 , A61B2017/00915
摘要： A novel coplanar X-ray guided method and aiming arm device for insertion of distal locking screws in intramedullary bone nails. Radiopaque target markers in the aiming arm enable the easy positioning of an X-ray source such that an X-ray beam is coplanar with the aiming arm transverse holes. After the X-ray source is accurately oriented, a single X-ray snapshot is enough to assess the exact distortion of the implanted intramedullary nail. The X-ray beam need not be coaxial with the nail holes. The aiming arm includes a mobile portion and a fixed portion fastened to the nail, and the aiming arm can be adjusted, displacing the mobile portion over the fixed portion, to compensate for the distortion of the intramedullary nail caused by implantation in bone.
摘要翻译：一种新颖的共面X射线引导方法和瞄准臂装置，用于将髓内骨钉中的远端锁定螺钉插入。瞄准臂中的不透射线目标标记使得能够容易地定位X射线源，使得X射线束与瞄准臂横向孔共面。在X射线源准确定向之后，单个X射线快照足以评估植入髓内钉的确切畸变。 X射线束不需要与钉孔同轴。瞄准臂包括可移动部分和紧固到钉子的固定部分，并且可调节瞄准臂，使可移动部分移动在固定部分上，以补偿由植入骨头引起的髓内钉的变形。

4. 发明授权

US07481766B2 Multiple-blade retractor 有权
标题翻译：多叶片牵开器
公开(公告)号：US07481766B2
公开(公告)日：2009-01-27
申请号：US10917560
申请日：2004-08-13
申请人： Andrew Lee , David Gerber
发明人： Andrew Lee , David Gerber
IPC分类号： A61B1/32
CPC分类号： A61B17/02 , A61B17/0206 , A61B17/0293 , A61B17/2804 , A61B17/2833
摘要： A retractor with multiple blades for use in surgery. The retractor may comprise first and second elongated portions which are pivotally connected to each other. A first blade may be connected to the first elongated portion and a second blade may be connected to the second elongated portion. The retractor may also comprise a sliding bar having a third blade. The sliding bar may be associated with the first and second elongated portions such that movement of the elongated portions relative to each other may result in movement of the sliding bar and, consequently, movement of the third blade relative to the first and second blades. In one embodiment, the retractor may comprise a tension limiting device so that the third blade may remain relatively stationary as the first and second blades are moved. The retractor may also comprise a fourth blade operatively connected to the first and second elongated portions. The fourth blade may be moved independently of the other blades or may move with the other blades. Also disclosed is a method of retracting tissue.
摘要翻译：具有多个刀片的牵开器用于手术。牵开器可以包括彼此枢转地连接的第一和第二细长部分。第一叶片可以连接到第一细长部分，并且第二叶片可以连接到第二细长部分。牵开器还可以包括具有第三叶片的滑动杆。滑动杆可以与第一和第二细长部分相关联，使得细长部分相对于彼此的移动可导致滑动杆的移动，并且因此导致第三叶片相对于第一和第二叶片的运动。在一个实施例中，牵开器可以包括张力限制装置，使得当第一和第二叶片移动时，第三叶片可保持相对静止。牵开器还可以包括可操作地连接到第一和第二细长部分的第四叶片。第四刀片可以独立于其他刀片移动，或者可以与其他刀片一起移动。还公开了一种缩回组织的方法。

5. 发明授权

US07476226B2 Tools and methods for creating cavities in bone 有权
公开(公告)号：US07476226B2
公开(公告)日：2009-01-13
申请号：US10738033
申请日：2003-12-18
申请人： Stuart Weikel , Nisra Thongpreda , Mike Lehmicke , Douglas Kephart , Larry Binder
发明人： Stuart Weikel , Nisra Thongpreda , Mike Lehmicke , Douglas Kephart , Larry Binder
IPC分类号： A61B17/56 , A61B17/58
CPC分类号： A61B17/8858 , A61B17/1604 , A61B17/1637 , A61B17/1671 , A61B17/320016 , A61B17/32002 , A61B17/7061 , A61B17/8822 , A61B90/39 , A61B2017/00004 , A61B2017/00261 , A61B2017/00557 , A61B2017/00867 , A61F2/44 , A61F2/4601
摘要： Tools for use in the creation of cavities in bones. The tools include a probe, a cannula that provides percutaneous passageway to the interior of the treated bone, a bone tamp, and a system for delivering bone filler material into the cavity. The bone tamp has a shaft that is inserted into the bone through the cannula. The end of the shaft that is inserted into the bone may have a flapper tip that extends out of axial alignment with the shaft upon deployment by the physician. Once the tip is deployed, the bone tamp can be rotated to form the cavity. The cavity may then be treated with a medicament, filled with bone filler material, or both. Other tools and materials described herein may be used to lift or restore the treated bone closer to its natural anatomy.

6. 发明申请

US20080262630A1 Drug-Impregnated Encasement 有权
标题翻译：药物浸渍包膜
公开(公告)号：US20080262630A1
公开(公告)日：2008-10-23
申请号：US12089574
申请日：2006-10-12
申请人： Mark Thomas Fulmer , David A. Armbruster , Robert Frigg , Elliott A. Gruskin , Sean Hamilton Kerr
发明人： Mark Thomas Fulmer , David A. Armbruster , Robert Frigg , Elliott A. Gruskin , Sean Hamilton Kerr
IPC分类号： A61F2/28
CPC分类号： A61M31/002 , A61B17/68 , A61B17/70 , A61B17/72 , A61B17/8028 , A61B2017/00004 , A61B2017/00893 , A61C8/0013 , A61F2/04 , A61F2/06 , A61F2/07 , A61F2002/072 , A61F2210/0004 , A61F2250/0067 , A61J3/00 , A61J2200/00 , A61L27/54 , A61L31/148 , A61L31/16 , A61M37/00 , A61M2205/04 , Y10T156/1051
摘要： A drug-impregnated sleeve for encasing a medical implant is provided. In one embodiment, the sleeve may include a body made of a biologically-compatible material that defines an internal cavity configured to receive the medical implant. In one embodiment, the biologically-compatible material is bioresorbable. The body may include a plurality of apertures, such as perforations or holes, extending from the cavity through the body. The sleeve may further include a first end, a second end, and a drug impregnated into the resorbable sheet. In one possible embodiment, the first end of the sleeve may be open for receiving the medical implant therethrough and the second end may be closed. The implant may be encased in the sleeve and implanted into a patient from which the drug is dispensed in vivo over time to tissue surrounding the implantation site. In one embodiment, the body is made from at least one sheet of a biologically-compatible material, hi one embodiment, the sleeve may be made in least in part from caprolactone to add stretchability to the sleeve.
摘要翻译：提供了用于封装医疗植入物的药物浸渍套管。在一个实施例中，套筒可以包括由生物相容的材料制成的主体，该主体限定了构造成接收医疗植入物的内部空腔。在一个实施方案中，生物相容性材料是生物可再吸收的。主体可以包括从空腔穿过主体延伸的多个孔，例如穿孔或孔。套筒还可以包括第一端，第二端和浸渍在可再吸收片中的药物。在一个可能的实施例中，套筒的第一端可以是敞开的，用于接收通过其中的医疗植入物，并且第二端可以是封闭的。植入物可以被封装在套筒中并且植入患者体内，药物在体内随着时间被分配到围绕植入部位的组织。在一个实施方案中，主体由至少一片生物相容性材料制成。在一个实施方案中，套筒可以至少部分地由己内酯制成以向套筒增加拉伸性。

7. 发明申请

US20080249532A1 Securing device to secure fixation devices to bone portions 有权
标题翻译：固定装置以固定固定装置到骨部分
公开(公告)号：US20080249532A1
公开(公告)日：2008-10-09
申请号：US11784331
申请日：2007-04-06
申请人： Robert J. Schoutens , Kan Naito , Ulrich Engenhardt , Bruno Wiesmann , Benjamin Straub , Ralf Oesterlein
发明人： Robert J. Schoutens , Kan Naito , Ulrich Engenhardt , Bruno Wiesmann , Benjamin Straub , Ralf Oesterlein
IPC分类号： A61B17/58
CPC分类号： A61B17/688 , A61B17/8861 , A61B17/8863 , A61B17/8869
摘要： The present invention discloses a securing device that is used to secure a fixation device to two bone portions to promote healing between the two bone portions. The bone portions commonly include a skull bone portion and a skull bone flap or implant, and the fixation device is commonly a cranial clamp. The securing device provides for securing the fixation device in a uniform, single movement as opposed to currently available products. The securing device has two handles pivotably connected, and a gripping means moveably associated with one handle. As the handles are activated, the gripping means travels proximally along the one handle and grips an elongated section of the fixation device and exerts a tensioning force along the shaft of the elongated section prior to the cutting means cutting the elongated shaft to secure the fixation device in place.
摘要翻译：本发明公开了一种用于将固定装置固定到两个骨部分以促进两个骨部之间愈合的固定装置。骨部通常包括颅骨部分和颅骨骨瓣或植入物，并且固定装置通常是颅骨夹具。与当前可用的产品相反，该固定装置用于将固定装置固定在均匀的单一运动中。固定装置具有可枢转地连接的两个手柄，以及可移动地与一个手柄相关联的夹紧装置。当手柄被启动时，抓握装置沿着一个把手向近侧行进，并且夹住固定装置的细长部分并且在切割装置切割细长轴之前沿着细长部分的轴施加张紧力，以固定固定装置到位。

8. 发明授权

US07377921B2 Damping element and device for stabilization of adjacent vertebral bodies 有权
标题翻译：用于稳定相邻椎体的阻尼元件和装置
公开(公告)号：US07377921B2
公开(公告)日：2008-05-27
申请号：US10497794
申请日：2002-03-28
申请人： Armin Studer , Robert Frigg
发明人： Armin Studer , Robert Frigg
IPC分类号： A61B17/56 , A61F2/30
CPC分类号： F16F3/10 , A61B17/7004 , A61B17/7028 , F16F1/123
摘要： A damping element (1) includes: (a) two spring elements (2, 4) which are coaxial with or parallel to a longitudinal axis (3) and two axially end-side connectors (5, 6), where (b) the first spring element (2) exhibits a spring rate F, (c) the second spring element (4) exhibits a spring rate f, and (d) the spring rates F and f are different. A device stabilizing adjacent vertebras, comprising (a) N pedicle screws of hooks (12), where N≧3 and where (b) each pedicle screw or pedicle hook (12) includes a receiving device (13) receiving a longitudinal affixation device (7) and where (c) an element (14) acting as a spring is inserted between two adjacent pedicle screws (12) or pedicle hooks.
摘要翻译：阻尼元件（1）包括：（a）与纵向轴线（3）同轴或平行的两个弹簧元件（2,4）和两个轴向端侧连接器（5,6），其中（b）第一弹簧元件（2）具有弹簧刚度F，（c）第二弹簧元件（4）具有弹簧刚度f，（d）弹簧刚度F和f不同。一种稳定相邻椎骨的装置，包括：（a）钩子（12）的N个椎弓根螺钉，其中N≥3，并且其中（b）每个椎弓根螺钉或椎弓根钩（12）包括容纳装置（13），所述接收装置接收纵向固定装置（7），并且其中（c）用作弹簧的元件（14）插入在两个相邻的椎弓根螺钉（12）或椎弓根钩之间。

9. 发明授权

US07316688B2 Cutting and forming device 有权
标题翻译：切割成型装置
公开(公告)号：US07316688B2
公开(公告)日：2008-01-08
申请号：US11233255
申请日：2005-09-21
申请人： Romano Matthys-Mark , Hans Gelpke
发明人： Romano Matthys-Mark , Hans Gelpke
IPC分类号： A61B17/58
CPC分类号： A61B17/685 , A61B17/848 , A61B17/8863 , B21F11/00 , B21F15/00 , B21F15/06 , B23D29/023 , B25B27/143
摘要： A cutting and forming device includes an outer sleeve, an inner sleeve, and a housing. The outer sleeve has a longitudinal axis, a front end, a rear end, and a borehole having an borehole axis. The inner sleeve, can be rotated in the outer sleeve's borehole and includes a front end, a rear end, and a borehole having a borehole axis. The housing with a central axis has a front end, a rear end, and a cavity which accommodates the outer sleeve and passes through the housing parallel to the central axis. The front end of the inner sleeve has a circular cutting edge which is concentric with the borehole axis of the inner sleeve, and the borehole at the front end of the outer sleeve has a constriction whose longitudinal axis is parallel to the borehole axis of the outer sleeve.
摘要翻译：切割和成形装置包括外套筒，内套筒和外壳。外套筒具有纵向轴线，前端，后端和具有钻孔轴线的钻孔。内套筒可以在外套筒的钻孔中旋转并且包括前端，后端和具有井眼轴线的钻孔。具有中心轴的壳体具有前端，后端和容纳外套筒并平行于中心轴线穿过壳体的空腔。内套筒的前端具有与内套筒的钻孔轴心同心的圆形切削刃，而外套筒前端的钻孔具有一个收缩部，其纵向轴线平行于外套筒的钻孔轴线袖。

10. 发明授权

US07300465B2 Intervertebral allograft spacer 有权
标题翻译：椎间同种异体移植间隔
公开(公告)号：US07300465B2
公开(公告)日：2007-11-27
申请号：US11150608
申请日：2005-06-10
申请人： David C. Paul , Hansjuerg Emch , Beat Schenk
发明人： David C. Paul , Hansjuerg Emch , Beat Schenk
IPC分类号： A61F2/44
CPC分类号： B29C43/006 , A61F2/28 , A61F2/30724 , A61F2/30744 , A61F2/3094 , A61F2/30942 , A61F2/30965 , A61F2/442 , A61F2/4455 , A61F2/4465 , A61F2/4611 , A61F2/4644 , A61F2002/2817 , A61F2002/2835 , A61F2002/2839 , A61F2002/30011 , A61F2002/30057 , A61F2002/30062 , A61F2002/30075 , A61F2002/30112 , A61F2002/30126 , A61F2002/30133 , A61F2002/30153 , A61F2002/30158 , A61F2002/302 , A61F2002/30228 , A61F2002/30233 , A61F2002/30238 , A61F2002/3024 , A61F2002/3028 , A61F2002/30324 , A61F2002/30327 , A61F2002/30329 , A61F2002/30331 , A61F2002/30354 , A61F2002/30377 , A61F2002/3038 , A61F2002/30382 , A61F2002/30383 , A61F2002/30387 , A61F2002/30433 , A61F2002/30434 , A61F2002/30436 , A61F2002/30441 , A61F2002/30448 , A61F2002/30459 , A61F2002/30462 , A61F2002/30472 , A61F2002/30477 , A61F2002/30481 , A61F2002/30492 , A61F2002/30494 , A61F2002/30507 , A61F2002/3051 , A61F2002/30515 , A61F2002/30593 , A61F2002/30599 , A61F2002/30604 , A61F2002/30616 , A61F2002/30617 , A61F2002/30714 , A61F2002/30733 , A61F2002/30772 , A61F2002/30782 , A61F2002/30785 , A61F2002/30787 , A61F2002/3082 , A61F2002/30841 , A61F2002/30843 , A61F2002/30892 , A61F2002/30894 , A61F2002/30904 , A61F2002/30909 , A61F2002/30957 , A61F2002/30971 , A61F2002/30975 , A61F2002/4475 , A61F2002/4635 , A61F2002/4649 , A61F2210/0004 , A61F2210/0061 , A61F2220/0025 , A61F2220/0033 , A61F2220/0041 , A61F2220/005 , A61F2220/0066 , A61F2220/0075 , A61F2230/0004 , A61F2230/0008 , A61F2230/0015 , A61F2230/0019 , A61F2230/0026 , A61F2230/0063 , A61F2230/0065 , A61F2230/0069 , A61F2250/0023 , A61F2250/0036 , A61F2250/0039 , A61F2250/0063 , A61F2250/0089 , A61F2250/0097 , A61F2310/00011 , A61F2310/00179 , A61F2310/00293 , A61F2310/00353 , B29C33/26 , B29L2031/3041 , Y10S623/925
摘要： An allogenic intervertebral implant for fusing vertebrae is disclosed. The implant is a piece of allogenic bone conforming in size and shape with a portion of an end plate of a vertebra. The implant has a wedge-shaped profile to restore disc height and the natural curvature of the spine. The top and bottom surfaces of the implant have a plurality of teeth to resist expulsion and provide initial stability. The implant according to the present invention provides initial stability need for fusion without stress shielding.
摘要翻译：公开了一种用于融合椎骨的同种异体椎间植入物。植入物是一块同位素骨，其尺寸和形状与椎骨端板的一部分一致。植入物具有楔形轮廓以恢复椎间盘的高度和脊柱的自然曲率。植入物的顶表面和底表面具有多个齿以抵抗排出并提供初始稳定性。根据本发明的植入物提供了没有应力屏蔽的融合的初始稳定性需求。

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