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1. 发明授权

US11273983B2 Multiposition lift 有权
公开(公告)号：US11273983B2
公开(公告)日：2022-03-15
申请号：US16984599
申请日：2020-08-04
申请人： Symbolic, LLC
发明人： Larry Sweet , Kil Kwak , Kirill Pankratov , Russell G. Barbour , William Johnson , Juergen D. Conrad , Juergen Baumbach , Ronald Kyslinger
IPC分类号： B65G1/137 , B65G1/04 , G06Q10/08
摘要： An automated storage and retrieval system includes a first independently operable section having a first number of predetermined storage and retrieval transactions, and a second independently operable section in communication with the first independently operable section and having a second number of predetermined storage and retrieval transactions. The first and second independently operable sections are configured to provide a respective number of predetermined storage and retrieval transactions so that the first number of predetermined storage and retrieval transactions substantially matches the second number of predetermined storage and retrieval transactions.

2. 发明申请

US20120046361A1 ETHYL PYRUVATE COMPOSITIONS AND METHODS 审中-公开
标题翻译：乙基吡咯烷酮组合物和方法
公开(公告)号：US20120046361A1
公开(公告)日：2012-02-23
申请号：US13214016
申请日：2011-08-19
申请人： Keith Skinner
发明人： Keith Skinner
IPC分类号： A61K31/22 , A61P3/04 , A61P3/00
CPC分类号： A61K31/22 , A61K31/185 , A61K31/19 , A61K31/194 , A61K31/352 , A61K31/455 , A61K31/714 , A61K36/28 , A61K36/898 , A61K2300/00
摘要： Compositions and methods are disclosed for use of ethyl pyruvate to boost energy, endurance, or to feel good, or to lose weight. Pharmaceutical preparations having ethyl pyruvate are disclosed herein as well.
摘要翻译：公开了使用丙酮酸乙酯来提高能量，耐力或感觉良好或减肥的组合物和方法。具有丙酮酸乙酯的药物制剂也在本文中公开。

3. 发明申请

US20080311093A1 STEM CELL SECRETIONS AND RELATED METHODS 审中-公开
标题翻译：干细胞分泌及相关方法
公开(公告)号：US20080311093A1
公开(公告)日：2008-12-18
申请号：US11952898
申请日：2007-12-07
申请人： Keith K. Skinner
发明人： Keith K. Skinner
IPC分类号： A61K35/12 , A61Q99/00
CPC分类号： A61K35/36 , A61K8/361 , A61K8/99 , A61Q7/00 , A61Q19/08
摘要： Stem cell secretions are derived from epithelial cells conditioned media. The stem cell secretions are then applied topically, orally, or rectally, etc., to derive health benefits from the growth factors and other molecules comprising the stem cell secretion. The stem cell secretion may optionally be modified by covalently bonding fatty acids to protect the molecules through the delivery process and to make them more readily available to cells.
摘要翻译：干细胞分泌源自上皮细胞条件培养基。然后将局部，口服或直肠等施用干细胞分泌物，从生长因子和包含干细胞分泌的其它分子获得健康益处。干细胞分泌可以任选地通过共价键合脂肪酸来修饰，以通过递送过程保护分子并使其更容易获得细胞。

4. 发明授权

US08329435B2 Methods for improved uptake of biological molecules 失效
标题翻译：改善生物分子吸收的方法
公开(公告)号：US08329435B2
公开(公告)日：2012-12-11
申请号：US12890451
申请日：2010-09-24
申请人： Keith K. Skinner
发明人： Keith K. Skinner
IPC分类号： C07K5/037
CPC分类号： A61K31/724 , C07K5/0215
摘要： A “one-step” process for production of peptides and other organic molecules which are both esters and also acetylated forms of the desired molecule. The ester may be a mono-ester, di-ester, or another poly-ester, complexed with a molecule for protecting the organic molecules in the digestive tract. The method allows simple adjustment of the delivery properties of the peptides produced, in particular adjustment or addition of lipiphilic tendencies. A therapeutic or nutrient made by this method comprises acetylated organic molecule esters, in particular an acetylated peptide ester or even an acetylated amino acid ester and demonstrates improved metabolic properties leading to increased efficiency for therapeutic and cosmetic purposes including oral, transdermal, sublingual, buccal, and topical administration. The present disclosure further teaches several specific examples of acetylated esters, including acetyl-glutathione-ester (mGSH), MCAR (carnosine), pyruvate and others modified from base forms by the methods of the present disclosure.
摘要翻译：用于生产肽和其它有机分子的一步法，其既是酯也是所需分子的乙酰化形式。酯可以是与用于保护消化道中的有机分子的分子络合的单酯，二酯或另一种聚酯。该方法允许简单调整所产生的肽的递送性质，特别是调节或添加脂质性倾向。通过该方法制备的治疗或营养包括乙酰化的有机分子酯，特别是乙酰化的肽酯或甚至乙酰化的氨基酸酯，并表现出改进的代谢性质，导致治疗和美容目的的效率增加，包括口服，经皮，舌下，口腔，和局部给药。本公开进一步教导了通过本公开的方法的乙酰化酯的几个具体实例，包括乙酰基 - 谷胱甘肽 - 酯（mGSH），MCAR（肌肽），丙酮酸和其它由碱形式修饰的酯。

5. 发明授权

US11708218B2 Automated storage and retrieval system 有权
公开(公告)号：US11708218B2
公开(公告)日：2023-07-25
申请号：US17152358
申请日：2021-01-19
申请人： Symbotic LLC
发明人： Michael J. Kapust , Gerald M. Friedman
IPC分类号： B65G1/04 , B65G1/137
CPC分类号： B65G1/0492 , B65G1/0435 , B65G1/1373
摘要： An autonomous transport vehicle including a frame forming a payload area, telescoping arms movably mounted to the frame, each telescoping arm being configured for extension and retraction relative to the frame along an extension axis to effect transfer of at least one pickface to and from the payload area, and traversal, relative to the frame, in at least one direction that is angled to the extension axis, and at least one tab extending from each telescoping arm where the at least one tab extends in a direction transverse to the direction of extension and retraction, and the at least one tab on one of the telescoping arms opposes the at least one tab on another of the telescoping arms.

6. 发明授权

US11562321B2 Storage and retrieval system 有权
公开(公告)号：US11562321B2
公开(公告)日：2023-01-24
申请号：US16950383
申请日：2020-11-17
申请人： Symbolic LLC
发明人： Kirill K. Pankratov , Juergen D. Conrad , Robert Hsiung , Larry M. Sweet
IPC分类号： G06Q10/08 , B65G1/04 , B65G1/06
摘要： A product order fulfillment system includes multiple decks arrayed at different levels and defining multilevel decks, at least one autonomous transport vehicle on each of the decks, and configured for holding and transporting a pickface on each deck, at least one lift, traversing and connecting more than one level of the decks, and arranged for lifting and lowering the pickface from the decks, and at least one pickface transfer station on each deck interfacing between the transport vehicle and the at least one lift to effect transfer of the pickface between the transport vehicle and the at least one lift, the at least one lift defines a fulfillment stream of mixed case pickfaces outbound from the multilevel decks to a load fill, at least one stream of the fulfillment stream has an ordered sequence of streaming pickfaces wherein the ordered sequence of streaming pickfaces is based on another fulfilment stream.

7. 发明授权

US09475649B2 Pickface builder for storage and retrieval systems 有权
标题翻译： Pickface构建器用于存储和检索系统
公开(公告)号：US09475649B2
公开(公告)日：2016-10-25
申请号：US13326869
申请日：2011-12-15
申请人： Stephen C. Toebes , Robert Sullivan
发明人： Stephen C. Toebes , Robert Sullivan
IPC分类号： B65G47/08 , B65G1/04 , B65G1/137 , B65G1/127
CPC分类号： B65G47/086 , B65G1/0485 , B65G1/127 , B65G1/1371
摘要： A pickface builder for a storage and retrieval system for storing goods units and having an in-feed conveyor and a picking device, each goods unit holding at least one product package therein, the pickface builder including a frame, a pusher member movably coupled to the frame, and a snugger member movably coupled to the frame, wherein the pickface builder is configured to receive goods units from the in-feed conveyor and the pusher member and snugger member are movable at least in a direction transverse to a direction of goods unit travel on the in-feed conveyor and configured to form the goods units into a pickface picked by the picking device as a unit and having a predetermined reference datum relating the pickface to a placement position of goods units forming the pickface along a storage surface of the storage and retrieval system.
摘要翻译：一种用于存储货物单元并具有进料输送机和拾取装置的存储和检索系统的拾取构件，每个货物单元在其中容纳至少一个产品包装，所述拾取构件包括框架，可移动地联接到框架和可移动地联接到框架的紧身构件，其中拾取构件构造成从进给输送器接收货物单元，并且推动构件和紧固构件至少在横向于货物单元行进方向的方向上可移动在所述进给输送机上并且构造成将所述货物单元形成为由所述拾取装置拾取的拾取单元作为一个单元，并且具有预定的参考数据，所述参考数据将所述接收面与沿着所述存储器的存储表面形成所述接收面的货物单元的放置位置相关联和检索系统。

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