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1. 发明授权

US10918479B2 Heart valve prosthesis 有权
公开(公告)号：US10918479B2
公开(公告)日：2021-02-16
申请号：US16160857
申请日：2018-10-15
申请人： SHANGHAI MICROPORT CARDIOFLOW MEDTECH CO., LTD.
发明人： Guoming Chen , Yu Li , Feng Huang , Lei Huang , Jianchao Han , Yihao Duan , Shaohui Chen , Qiyi Luo
IPC分类号： A61F2/24
摘要： A stent (1) used for a heart valve prosthesis and the heart valve prosthesis that includes the stent (1) and is used for heart valve replacement. The stent is configured to support a heart valve (3) and includes, along a longitudinal axis, an inflow section (8), an outflow section (6) and a transition section (7) between the inflow section (8) and the outflow section (6). The stent (1) has a contracted delivery configuration and an expanded deployed configuration. In the expanded deployed configuration, the inflow section (8) defines a concave contour that is complementary to a structure of a native valve annulus. The concave contour enables self-deployment and close adherence of the stent (1), thereby preventing its displacement and perivalvular leakage after implantation.

2. 发明申请

US20220016400A1 BALLOON DILATION CATHETER, BALLOON AND PREPARATION METHOD THEREFOR 有权
公开(公告)号：US20220016400A1
公开(公告)日：2022-01-20
申请号：US17291530
申请日：2019-11-05
申请人： SHANGHAI MICROPORT CARDIOFLOW MEDTECH CO., LTD.
发明人： Bin YUE , Jingwei JIA , Guoming CHEN , Yu LI
IPC分类号： A61M25/10 , A61L29/04 , A61L29/06
摘要： A balloon dilation catheter, a balloon (10) and preparation method therefor. The balloon (10) is prepared by co-mixing at least two of L25, TR55, TR90, and TR70, and has high puncture resistance and low compliance with respect to a balloon (10) made of a single nylon material. The balloon (10) is preferably a hollow multilayer structure, and the puncture resistance of the balloon (10) can be further improved and the compliance can be further reduced with respect to a single-layer structure.

3. 发明申请

US20210154007A1 DELIVERY DEVICE 有权
公开(公告)号：US20210154007A1
公开(公告)日：2021-05-27
申请号：US17257139
申请日：2019-08-30
申请人： SHANGHAI MICROPORT CARDIOFLOW MEDTECH CO., LTD.
发明人： Xuwen WU , Baozhu GUI , Jie MEI , Guoming CHEN , Yu LI
IPC分类号： A61F2/24
摘要： A delivery device (1, 1′) for loading, delivering and deploying an implant (2) includes a handle (18), an inner tubular core (11), a sheath tube (13) and a guide tip (12). The inner tubular core (11) is coupled, at a proximal end thereof, to an inner tubular core actuation member arranged in the handle (18), and the guide tip (12) is disposed at a distal end of the inner tubular core (11) and fixedly connected to a distal end of the sheath tube (13). The sheath tube is (13) sleeved over the inner tubular core (11). Here, the proximal end of each component refers to the end thereof closer to the handle (18), while the distal end thereof is the end farther away from the handle (18). As the sheath tube (13) is fixedly connected, at the distal end thereof, to the guide tip (12), the implant (2) is loaded at the proximal end of the sheath tube (13) in the delivery device (1, 1′). During deployment of the implant (2), the sheath tube (13) is caused to move toward distal end, that is, the sheath tube (13) continues moving toward a target site for the implant (2), rather than moves backward to the handle (18). This can effectively avoid the problems that may arise from retraction of the sheath tube (13) through a three-dimensionally curved path, such as unstable or even faulty deployment of the implant (2), thus allowing deployment of the implant (2) with enhanced quality.

4. 发明授权

US10813754B2 Driving handle for delivering implant, and delivery system 有权
公开(公告)号：US10813754B2
公开(公告)日：2020-10-27
申请号：US15568240
申请日：2016-04-27
申请人： SHANGHAI MICROPORT CARDIOFLOW MEDTECH CO., LTD.
发明人： Zhixiu He , Xiang Liu , Baozhu Gui , Yu Li , Haishan Wang , Mingming Wu , Yunlei Wang
IPC分类号： A61F2/24 , A61F2/95 , A61F2/966 , A61F2/46
摘要： A drive handle and system for delivering an implant are disclosed. The drive handle includes a manual control unit, an electrical control unit and a transmission mechanism. The manual control unit is connected to the transmission mechanism to actuate the transmission mechanism to drive a delivery catheter for delivering the implant. The electrical control unit is connected to the transmission mechanism to actuate the transmission mechanism to drive the delivery catheter. The drive handle is switchable between a manual drive/control mode and an electrical drive/control mode to drive the delivery catheter to deliver the implant. The operation is simple, and the operating physician can take full advantage of the two modes to perform the surgical procedure based on his/her own operational preferences. This can result in higher surgical accuracy. Further, by providing these two modes, the apparatus has an increased the security and a reduced surgical risk.

5. 发明授权

US10123871B2 Implant capsule and implant delivery system 有权
公开(公告)号：US10123871B2
公开(公告)日：2018-11-13
申请号：US15036902
申请日：2014-11-14
申请人： SHANGHAI MICROPORT CARDIOFLOW MEDTECH CO., LTD.
发明人： Xiang Liu , Baozhu Gui , Yu Li , Mingming Wu , Zhixiu He , Haishan Wang
IPC分类号： A61F2/962 , A61F2/24 , A61M25/00 , A61F2/958 , A61F2/966
摘要： An implant capsule (10) and an implant delivery system are disclosed. The implant capsule (10) includes, sequentially from a proximal end to a distal end, a flexural section (102, 102a-102e), a reinforcement section (101, 101a-101e) and a radiopaque reinforcement ring (104a-104e). The reinforcement section (101, 101a-101e) has higher strength than the flexural section (102, 102a-102e). The implant delivery system includes the implant capsule (10). The implant capsule (10) can ensure the implant to be deployed in a coaxial condition and prevent over-expansion due to large expansion forces exerted by a stent of the implant.

6. 发明授权

US09889029B2 Implant delivery system 有权
公开(公告)号：US09889029B2
公开(公告)日：2018-02-13
申请号：US14430139
申请日：2013-09-22
申请人： SHANGHAI MICROPORT MEDICAL (GROUP) CO., LTD.
发明人： Yu Li , Xiang Liu , Mingming Wu , Haishan Wang , Guoming Chen , Shaohui Chen
IPC分类号： A61F2/24 , A61F2/962 , A61F2/82 , A61M3/02 , A61M25/00 , A61M25/01 , A61M25/09 , A61M39/10 , A61F2/95
CPC分类号： A61F2/962 , A61F2/2436 , A61F2/82 , A61F2002/9505 , A61F2002/9517 , A61F2250/0098 , A61M3/02 , A61M25/0021 , A61M25/0074 , A61M25/0108 , A61M25/0136 , A61M25/0147 , A61M25/09 , A61M39/10 , A61M2025/0177 , A61M2205/0216
摘要： An implant delivery system is disclosed which includes an inner tube assembly, an outer tube assembly and a functional handle. The functional handle includes a threaded rod, a push-pull control member, a casing tube, a displacement tube, an inner tube fixing member, an outer tube fixing member and a stability tube fixing member. The threaded rod extends through a bore of the displacement tube. A fastener of the push-pull control member is able to engage a thread provided on a leading portion of the threaded rod. A trailing portion of the threaded rod is provided with a knob. The push-pull control member includes a fastener, springs and a button. The fastener is able to extend through a slot to engage a thread of the threaded rod in the displacement tube. The springs are configured to cause an automatic locking of the fastener and the threaded rod. The button is provided on the fastener. A cylindrical shell drives the displacement tube to move forward or backward along its longitudinal axis to cause the outer tube assembly to accordingly advance or retract. The delivery system can quickly, stably and accurately insert an implant into a target location.

7. 发明申请

US20220054265A1 DELIVERY CATHETER AND DELIVERY DEVICE FOR ARTIFICIAL VALVE 有权
公开(公告)号：US20220054265A1
公开(公告)日：2022-02-24
申请号：US17418118
申请日：2019-12-20
申请人： SHANGHAI MICROPORT CARDIOFLOW MEDTECH CO., LTD.
发明人： Xuwen WU , Jie MEI , Baozhu GUI , Guoming CHEN , Yu LI
IPC分类号： A61F2/24
摘要： A prosthetic valve delivery catheter and device. The delivery catheter includes an outer sheath assembly and an inner sheath assembly. The outer sheath assembly includes a capsule in which a prosthetic valve can be received and an outer sheath fixedly connected at one end to the capsule. The inner sheath assembly includes an inner sheath and an anchor fixedly connected to the inner sheath. The inner sheath assembly is arranged within a lumen of the outer sheath assembly, and the capsule and the anchor form a circumferentially indexed fit therebetween. With this design, the anchor and the capsule can be driven to rotate under the action of circumferential rotation of the inner sheath, thus the matching between the prosthetic valve and a native valve annulus can be adjusted. Moreover, the capsule can be driven to move axially under actuation of the outer sheath to allow release of the prosthetic valve.

8. 发明授权

US10966755B2 Implant delivery apparatus 有权
公开(公告)号：US10966755B2
公开(公告)日：2021-04-06
申请号：US16343562
申请日：2017-09-22
申请人： SHANGHAI MICROPORT CARDIOFLOW MEDTECH CO., LTD.
发明人： Zhixiu He , Baozhu Gui , Yu Li
IPC分类号： A61B17/34 , A61B17/00 , A61F2/24 , A61F2/95
摘要： An implant delivery device (100) includes a casing (110); and inner and outer tube driving members (150, 160), an inner tube (120), an intermediate tube (130), an outer tube (140) and an air-evacuation locking assembly (170), each at least partially accommodated in the casing (110). The three tubes are sequentially nested in one another, and first, second and third spaces are formed between neighbouring tubes. The inner tube driving member (150) has a proximal end that is sealingly fixed to a proximal end of the inner tube (120), and the outer tube driving member (160) is sealingly fixed to a proximal end of the outer tube (140). The intermediate tube (130) has a proximal end that is sealingly fixed to the inner tube driving member (150), and the intermediate tube extends through and is sealingly connected to the outer tube driving member (160). The air-evacuation locking assembly (170) is detachably coupled to the inner tube driving member (150). The inner tube driving member (150) and the air-evacuation locking assembly (170) are provided with first and second air-evacuation channels (A, B), respectively. When the air-evacuation locking assembly (170) is coupled to the inner tube driving member (150), the second air-evacuation channel (B) is brought into communication with the second and third spaces via the first air-evacuation channel (A) and the first space. The inner tube driving member (150) is coupled to the casing (110) by the air-evacuation locking assembly (170). When the air-evacuation locking assembly (170) is disconnected from the inner tube driving member (150), the inner tube driving member (150) remains in slidable connection with the casing (110).

9. 发明申请

US20210052379A1 CARDIAC VALVE PROSTHESIS AND STENT THEREOF 有权
公开(公告)号：US20210052379A1
公开(公告)日：2021-02-25
申请号：US16958518
申请日：2018-11-23
申请人： SHANGHAI MICROPORT CARDIOFLOW MEDTECH CO., LTD.
发明人： Chunxia ZHAO , Ming YANG , Guoming CHEN , Yu LI
IPC分类号： A61F2/24
摘要： The present application relates to a cardiac valve prosthesis and a stent thereof. The stent comprises an inflow channel, an outflow channel, and a transitional area between the inflow channel and the outflow channel along an axial direction; the outflow channel comprises a cyclic structure and at least two convex structures extending along the axial direction; the at least two convex structures are respectively connected to the end of the cyclic structure distant from the transitional area; a restricted vacant area is formed between adjacent convex structures. The cardiac valve prosthesis and the stent thereof are not only suitable for multiple types of valve replacement, risks of injuries and operation costs are reduced for patients, and the influence of the stent to cardiac functions is minimized.

10. 发明授权

US10098769B2 Device and method for loading implant into delivery system 有权
公开(公告)号：US10098769B2
公开(公告)日：2018-10-16
申请号：US15032456
申请日：2014-10-31
申请人： SHANGHAI MICROPORT CARDIOFLOW MEDTECH CO., LTD.
发明人： Xiang Liu , Mingming Wu , Yu Li , Zhixiu He , Baozhu Gui , Haishan Wang , Guoming Chen , Shaohui Chen , Qiyi Luo
IPC分类号： A61F2/95 , A61F2/24 , B65B5/04
摘要： A device and method for loading an implant into a delivery system are disclose which are capable of simplifying operations required in interventional surgery using the implant. The device includes a guide cap (1), a guider (2) and a guiding tube (3). The guide cap (1) has a conical section (101) and a straight or conical tube (103) in communication with a small open end (102) of the conical section, and the conical section has a large open end (104) that flares outward, thereby forming a flange (105) facing the tube (103). The guider (2) has tapered sections (9, 10) that are tapered along an axis of the guider and thus form large and small open ends (8, 11). The small open end (11) has a diameter greater than a diameter of the small open end (102) of the conical section of the guide cap (1). The guide cap (1) and the guider (2) are so sized that the flange (105) can cover and be locked to the guider (2), with an end portion of the straight or conical tube (103) protruding from the small open end (11) of the guider (2). The guiding tube (3) is a round tube with two open ends, in which the first open end has a diameter greater than the diameter of the small open end (102) of the conical section of the guide cap and smaller than the diameter of the small open end (11) of the guider.

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