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1. 发明授权

US12130171B2 Monolithic weighing system and method for producing same 有权
公开(公告)号：US12130171B2
公开(公告)日：2024-10-29
申请号：US17746070
申请日：2022-05-17
申请人： SARTORIUS LAB INSTRUMENTS GMBH & CO. KG
发明人： Jonas Bode , Matthias Geisler
IPC分类号： G01G7/00 , B22F10/64 , B22F10/66 , B33Y10/00 , B33Y40/20 , B33Y80/00
CPC分类号： G01G7/00 , B22F10/64 , B22F10/66 , B22F2301/052 , B22F2301/10 , B22F2301/15 , B22F2998/10 , B33Y10/00 , B33Y40/20 , B33Y80/00
摘要： A monolithic weighing system (100) includes a plurality of levers (120), which are joined together by thin-section joints (110). The levers, on the one hand, and the thin-section joints, on the other hand, are made of different materials or material combinations; and the levers, adjoining one of the thin-section joints on both sides thereof, have a first material (21), and the thin-section joint has a second material (22) which is different from the first material. An associated method includes (i) an additive manufacturing process, in which different materials, including the first and second material (21, 22), are applied in layers and are joined to form a single-piece weighing system blank (10), wherein the weighing system blank (10) has prospective lever regions (12) and prospective thin-section joint regions (11), and (ii) subsequent subtractive finishing of the weighing system blank at least on the prospective thin-section joint regions to obtain the weighing system.

2. 发明公开

US20240294607A1 RECOMBINANT PROTEINS BASED ON FIBRINOGEN 审中-公开
公开(公告)号：US20240294607A1
公开(公告)日：2024-09-05
申请号：US17925551
申请日：2021-05-20
申请人： Sartorius Lab Instruments GmbH & Co. KG
发明人： Thomas SCHEPER , Iliyana PELANOVA , Pia GELLERMANN , Sabrina GRÜNERT
IPC分类号： C07K14/75 , A61K38/00 , C12N15/70
CPC分类号： C07K14/75 , C12N15/70 , A61K38/00 , C07K2319/21
摘要： The present invention relates to isolated, recombinant polypeptides comprising the gamma chain of fibrinogen and a His-Tag. The present invention further relates to nucleic acids encoding said polypeptides, vectors comprising said nucleic acids, host cells, preferably bacterial host cells, comprising said nucleic acids or vectors, biohybrid materials comprising conjugates comprising said polypeptides, uses of the above, and methods for producing said polypeptides.

3. 发明申请

US20230043909A1 GRAVIMETRIC MEASURING DEVICE 有权
公开(公告)号：US20230043909A1
公开(公告)日：2023-02-09
申请号：US17971879
申请日：2022-10-24
申请人： SARTORIUS LAB INSTRUMENTS GMBH & CO. KG
发明人： Malte STAENDER
IPC分类号： G01G21/28 , G01G21/22
摘要： A gravimetric measuring device (10, 10′, 10″, 10′″) includes a balance base body (12) and a top unit (14, 14′, 14″, 14′″), wherein the balance base body (12) has a balance base body wall (20), to which the top unit (14, 14′, 14″, 14′″) can be reversibly fixed, and a weighing system with a load receptor (22) passing through the balance base body wall (20) and the top unit (14, 14′, 14″, 14′″). A plurality of optical, magnetic, tactile, radio, thermal, electrical and/or electronic interfaces (201) coupled to a balance electronics are arranged on the balance base body wall (20), at least one of which interfaces is connected to a corresponding interface of the top unit (14, 14′, 14″, 14′″) to form an optical, magnetic, tactile, radio, thermal, electrical or electronic connection between the top unit (14, 14′, 14″, 14′″) and the balance electronics.

4. 发明申请

US20220404194A1 GRAVIMETRIC MEASURING DEVICE 有权
公开(公告)号：US20220404194A1
公开(公告)日：2022-12-22
申请号：US17891708
申请日：2022-08-19
申请人： SARTORIUS LAB INSTRUMENTS GMBH & CO. KG
发明人： Bettina EMMERMANN , Alexander BERGER , Reinhold FELDMANN , Winfried GRAF
IPC分类号： G01G21/28 , G01G19/14 , G01G21/22 , G01G21/23
摘要： A gravimetric measuring device includes a weighing chamber with a vertical weighing chamber wall, which is formed as a support structure (14) with cover modules (28) detachably fixed thereto on the weighing chamber side, each cover module (28) having, on its weighing chamber side, a module front wall (30) covering the support structure (14) at least partially. The cover modules (28) have locking cantilevers (38) directed towards the support structure such that the locking cantilevers (38) are provided with vertically directed through-openings (40) which are aligned with corresponding through-openings (20, 22) of the support structure (14). The cover modules (28) are locked to the support structure (14) with locking rods (42) which pass through the mutually aligned through-openings (40; 20, 22) of the cover modules (28) and the support structure (14).

5. 发明授权

US10350525B2 Connecting structure for connecting a filter housing to a filter housing retaining structure, cleaning system, filter housing cover for a filter housing and method for connecting a filter housing cover to a filter housing retaining structure 有权
公开(公告)号：US10350525B2
公开(公告)日：2019-07-16
申请号：US15523756
申请日：2015-11-25
申请人： SARTORIUS LAB INSTRUMENTS GMBH & CO. KG
发明人： Roman Ritzka , Sebastian Purmann , Richard Brisland
IPC分类号： B01D35/30 , B01D15/08 , C02F1/28
摘要： A connecting structure connects a filter housing to a filter housing retaining structure. The connecting structure conducts a liquid that is to be cleaned to the filter housing and discharges a purified liquid. The connecting structure includes a filter housing cover that connects to the filter housing and that receives a filter medium. The filter housing cover has attachment elements that connect to corresponding attachment elements of the filter housing retaining structure to establish an exchange of fluids between the filter housing retaining structure and the filter housing. Filter housing cover guides are on opposing sides of the filter housing cover; and guides on the filter housing retaining structure engage the filter housing cover guides when connecting the attachment elements of the filter housing cover with the attachment elements of the filter housing retaining structure to support and linearly guide the filter housing cover during the connection process.

6. 发明授权

US09560938B2 Pan lifting device 有权
标题翻译：电梯升降装置
公开(公告)号：US09560938B2
公开(公告)日：2017-02-07
申请号：US15185530
申请日：2016-06-17
申请人： SARTORIUS LAB INSTRUMENTS GMBH & CO. KG
发明人： Olaf Dudda , Wilfried Spannagel , Caroline Schroeder , Daniel Faerger , Joerg Siedel
IPC分类号： A47J45/00 , A47J45/10 , B25B9/02
CPC分类号： A47J45/10 , B25B9/02 , G01N5/045
摘要： A pan lifting device configured to grip a pan of a balance with a positive fit has a pincer-shaped end (12) and a handle (14). A blade-shaped supporting projection (16) of the pan lifting device is configured to accommodate the bottom (28) of the pan and a bent-over beak (18) of the pan lifting device is configured to clamp the rim (30) of the pan.
摘要翻译：构造成以正配合握住平衡盘的盘升降装置具有钳形端（12）和手柄（14）。盘升降装置的叶片形支撑突起（16）被构造成容纳盘的底部（28），并且盘升降装置的弯曲的喙（18）被构造成将轮辋（30）锅

7. 发明授权

US09546899B2 Carrier unit for a weight switching device and weighing cell 有权
标题翻译：用于重量切换装置和称重传感器的载体单元
公开(公告)号：US09546899B2
公开(公告)日：2017-01-17
申请号：US14273973
申请日：2014-05-09
申请人： Sartorius Weighing Technology GmbH
发明人： Sigo Muelich , Ulrich Bajohr , Thomas Fehling
IPC分类号： G01G21/23 , G01G21/08 , G01G21/26 , G01G23/01
CPC分类号： G01G21/08 , G01G21/26 , G01G23/01 , G01G23/012 , Y10T74/18856
摘要： A carrier unit for a weight switching device includes a first shift weight carrier (34-1) which moves vertically in relation to a base, for vertically mounting a first shift weight arrangement (22-1R, 22-1L) which has two spaced-apart, parallel carrier arms (30-1R, 30-1L) connected by a bridging piece (32-1). A second shift weight carrier (34-2R, 34-2L) for vertically mounting, with play, a second shift weight arrangement (22-2R, 22-2L) which likewise has two spaced-apart, parallel carrier arms (30-2R, 30-2L) connected by another bridging piece (32-2), is likewise arranged in a vertically movable manner in relation to the base. The carrier arm pair (30-1R, 30-10 of the first shift weight carrier (34-1) is arranged between and parallel to the carrier arm pair (30-2R, 30-2L) of the second shift weight carrier (34-2), and each shift weight carrier (34-1; 34-2) is articulated to a common crosspiece (12) by two parallel links (23-1R, 23-1L; 23-2R, 23-2L).
摘要翻译：一种用于重量切换装置的承载单元包括相对于基座垂直移动的第一换挡重载架（34-1），用于垂直安装第二换挡重物装置（22-1R，22-1L）通过桥接件（32-1）连接的平行载臂（30-1R，30-1L）。一种用于垂直安装第二变速重量装置（22-2R，22-2L）的第二变速重量载体（34-2R，34-2L），它们同样具有两个间隔开的平行载臂（30-2R ，30-2L）通过另一个桥接件（32-2）连接，同样可相对于底座以垂直方式移动。第一变速重载体（34-1）的承载臂对（30-1R，30-10）布置在第二变速重载体（34）的承载臂对（30-2R，30-2L）之间并平行 -2），并且每个换档重量载体（34-1; 34-2）通过两个并联连杆（23-1R，23-1L; 23-2R，23-2L）铰接到公共横档（12）。

8. 发明授权

US09024797B2 Integrating A/D converter 有权
标题翻译：集成A / D转换器
公开(公告)号：US09024797B2
公开(公告)日：2015-05-05
申请号：US14486129
申请日：2014-09-15
申请人： Sartorius Lab Instruments GmbH & Co. KG
发明人： Heinrich Feldotte , Heyko Holst
IPC分类号： H03M1/34 , H03M1/00 , G01R19/00 , H03M1/12
CPC分类号： H03M1/002 , G01R19/0084 , H03M1/089 , H03M1/12 , H03M1/50
摘要： In an integrating A/D converter, first and second reference voltage inputs (18, 20) alternatingly connect through a reference voltage switch (16, 16′) via a first reference resistor (Rref) to an inverting input (122) of an integrator (12). A comparator (22) connected downstream of the integrator (12) compares a test voltage applied to its test voltage input (221) with a comparator reference voltage applied to its reference voltage input (222). This input (221) is connected to- the output (126) of the integrator (12). A control device (40) actuates the first reference voltage switch (16, 16′) in a pulsed manner and measures the time intervals between the individual switching processes. An inverter (24) inverting a measuring voltage (UM) and a first heating resistor (RMH) coupled thermally with a measuring resistor (RM), are connected in series between the measuring voltage input (14) and the output of the first reference voltage switch (16, 16′).
摘要翻译：在集成A / D转换器中，第一和第二参考电压输入端（18,20）通过第一参考电阻器（Rref）交替地通过参考电压开关（16,16'）连接到积分器的反相输入端（12）。连接在积分器（12）下游的比较器（22）将施加到其测试电压输入（221）的测试电压与施加到其参考电压输入（222）的比较器参考电压进行比较。该输入（221）连接到积分器（12）的输出端（126）。控制装置（40）以脉冲方式致动第一参考电压开关（16,16'），并测量各个开关过程之间的时间间隔。将测量电压（UM）和与测量电阻（RM）热耦合的第一加热电阻（RMH）反相的逆变器（24）串联连接在测量电压输入（14）和第一参考电压开关（16,16'）。

9. 发明申请

US20210364343A1 GRAVIMETRIC MEASURING SYSTEM 有权
公开(公告)号：US20210364343A1
公开(公告)日：2021-11-25
申请号：US17394787
申请日：2021-08-05
申请人： SARTORIUS LAB INSTRUMENTS GMBH & CO. KG
发明人： Heinrich FELDOTTE , Michael LAUBSTEIN , Heyko HOLST
IPC分类号： G01G23/48 , G01G21/28
摘要： A gravimetric measuring system (10), includes a balance (12) with a weighing chamber (22), surrounded by a weighing chamber wall (23, 24, 26, 28); an electromechanical weighing system (181); and an electronic control apparatus (36) for controlling the system operation according to algorithms stored in a memory (363) thereof; and a plurality of functional modules (14, 16), configured to be inserted, into module receptacles (283), arranged on the weighing chamber wall (28). Each module receptacle (283) has a device-side identification interface component (30a); and each functional module has a corresponding module-side identification interface component (306). The control apparatus (36) identifies each functional module (14, 16) inserted into a module receptacle (283), through interaction between the respective device-side and module-side identification interface components (30a, b) and selects one of a plurality of operating routines according to algorithms stored in the memory.

10. 发明授权

US11021700B2 Method for purifying viral vectors 有权
公开(公告)号：US11021700B2
公开(公告)日：2021-06-01
申请号：US15677175
申请日：2017-08-15
申请人： SARTORIUS LAB INSTRUMENTS GMBH & CO. KG
发明人： Paul Stephen Carter , Sara Margareta Nilsson
IPC分类号： C12N15/10 , C12N15/86 , A61K48/00 , C12N7/00 , C12N7/02
摘要： The invention relates to methods of purifying viral vectors from cell culture. In particular, the invention relates to a method of purifying a supernatant containing viral vectors from a cell culture by removing cells by filtering the cell culture using diatomaceous earth.

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