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1. 发明授权

US10060870B2 Method and apparatus for monitoring an underground object 有权
公开(公告)号：US10060870B2
公开(公告)日：2018-08-28
申请号：US15029998
申请日：2014-11-13
申请人： RHEINISCH-WESTFÄLISCHE TECHNISCHE HOCHSCHULE AACHEN
发明人： Michael Raupach , Kenji Reichling , Christian Helm
IPC分类号： G01V3/02 , G01V3/04 , G01N27/04 , G01V3/06 , G01V3/08 , G01N33/38 , G01N33/20 , G01N33/24 , G01V3/20 , G01V3/22
CPC分类号： G01N27/048 , G01N33/20 , G01N33/24 , G01N33/383 , G01V3/02 , G01V3/04 , G01V3/06 , G01V3/08 , G01V3/20 , G01V3/22
摘要： The invention relates to a system for monitoring a substratum (1) with regard to damage and/or for protecting a substratum (1) from damage. The system comprises: an electrolytically active layer (4), which has a moisture-dependent electrical resistance; at least one electrode pair, the spaced-apart electrodes (3a, 3b) of which are connected to each other by means of the electrolytically active layer (4); and a measuring device, by means of which a property, in particular an electrical quantity of the electrolytically active layer (4) or of the electrodes (3a, 3b), can be measured by using electrodes (3a, 3b) of at least one electrode pair, in particular of each electrode pair, and/or a control device, by means of which a voltage can be applied to the electrodes (3a, 3b) of at least one electrode pair, in particular of each electrode pair. At least one of the electrodes (3a, 3b) of the at least one electrode pair is designed as a planar electrode in the electrolytically active layer (4), in particular the plane of said at least one electrode is oriented parallel to the surface of the substratum (1). The invention further relates to a method for producing a system for monitoring and/or for protecting a substratum, to a method for monitoring a substratum with regard to damage, and to a method for protecting a substratum from damage, in particular moisture damage and/or damage as a result of the penetration of harmful substances.

2. 发明授权

US10829791B2 Means and methods for itaconic acid production 有权
公开(公告)号：US10829791B2
公开(公告)日：2020-11-10
申请号：US15127894
申请日：2015-03-20
申请人： Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen , Philipps-Universitaet Marburg
发明人： Michael Boelker , Wolfgang Buckel , Sandra Hartmann , Lars M. Blank , Nick Wierckx , Elena Geiser
IPC分类号： C12P7/46 , C12N1/15 , C12N1/19 , C12N9/88 , C12N9/90 , C07K14/37 , C12N15/52 , C12P7/44 , C12N9/02
摘要： The present invention relates to a method of producing itaconic acid. Further the present invention relates to nucleic acids encoding an aconitate-delta-isomerase (ADI) and trans-aconitate decarboxylase (TAD) and uses of such nucleic acids. Provided is additionally a recombinant host cell engineered to overexpress nucleic acids of the present invention. Furthermore an expression cassette and a vector are provided which include the respective nucleic acid.

3. 发明授权

US09370613B2 Axial-flow blood pump 有权
标题翻译：轴流血泵
公开(公告)号：US09370613B2
公开(公告)日：2016-06-21
申请号：US14395337
申请日：2013-07-17
申请人： Po-Lin Hsu , Ulrich Steinseifer , Jack Parker , Ruediger Autschbach
发明人： Po-Lin Hsu , Ulrich Steinseifer , Jack Parker , Ruediger Autschbach
IPC分类号： A61M1/12 , A61M1/10 , A61F2/82
CPC分类号： A61M1/125 , A61F2/82 , A61M1/101 , A61M1/1013 , A61M1/102 , A61M1/1024 , A61M1/1029 , A61M1/1031 , A61M1/1036 , A61M1/122 , A61M2205/04 , A61M2205/103 , A61M2210/12
摘要： An axial-flow blood pump has a rotatable impeller assembly rotatable about an axis and itself having a radially projecting blade and permanent magnets, A stationary stator assembly has stator windings interacting with the permanent magnets and a bearing system supporting the rotatable impeller assembly for rotation about the axis relative to the stator assembly. A stent implantable into a blood vessel is connected to ends of supports for coaxially mounting the stator assembly carrying the impeller assembly in the stent.
摘要翻译：轴向血液泵具有可旋转的叶轮组件，其可以围绕轴线旋转并且本身具有径向突出的叶片和永磁体。固定定子组件具有与永磁体相互作用的定子绕组和支撑可旋转叶轮组件以便围绕相对于定子组件的轴线。可植入血管的支架连接到支撑件的端部，以将承载叶轮组件的定子组件同轴地安装在支架中。

4. 发明申请

US20140170663A1 METHYLATION SIGNATURE FOR REPLICATIVE SENESCENCE OF CELLS IN CULTURE 审中-公开
标题翻译：文化中细胞代谢感受的甲基化标记
公开(公告)号：US20140170663A1
公开(公告)日：2014-06-19
申请号：US14236634
申请日：2012-08-06
申请人： Wolfgang Wagner , Carmen Koch , Sylvia Joussen , Anne Schellenberg
发明人： Wolfgang Wagner , Carmen Koch , Sylvia Joussen , Anne Schellenberg
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q1/6881 , C12Q2600/154 , C12Q2600/156
摘要： A method for determining a replicative senescence status of a cell includes determining a methylation status of at least one CpG-dinucleotide within a region of at least one of about 50,000 bp upstream and downstream of at least one CpG-dinucleotide selected from the group consisting of GRM7-CpG-site #1, CASR-CpG-site #1, PRAMEF2-CpG-site #1, SELP-CpG-site #1, CASP14-CpG-site #1, and KRTAP13-3-CpG-site #1. The methylation status of each of the at least one CpG-dinucleotide determined is compared with a reference methylation status of the respective CpG-dinucleotide.
摘要翻译：确定细胞的复制衰老状态的方法包括确定至少一个CpG二核苷酸在至少一个CpG二核苷酸的上游和下游约50,000bp的区域内的甲基化状态，所述至少一个CpG-二核苷酸选自 GRM7-CpG位点＃1，CASR-CpG位点＃1，PRAMEF2-CpG位点＃1，SELP-CpG位点＃1，CASP14-CpG位点＃1和KRTAP13-3-CpG位点＃1 。将所测定的至少一种CpG二核苷酸中的每一个的甲基化状态与相应CpG-二核苷酸的参考甲基化状态进行比较。

5. 发明申请

US20220285794A1 METHOD FOR CONTACTING THE BATTERY CELLS OF A BATTERY MODULE, AND BATTERY EXTINGUISHING DEVICE THEREFOR 有权
公开(公告)号：US20220285794A1
公开(公告)日：2022-09-08
申请号：US17633425
申请日：2020-09-17
申请人： Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen
发明人： Falko FIEDLER , Georg BERGWEILER , Soeren BETHLEHEM
IPC分类号： H01M50/516 , A62C3/16 , A62C35/13 , H01M10/6567 , H01M50/204
摘要： In a method and apparatus for contacting battery cells of a battery module by welding, module of at least two battery cells is inserted into a battery module holder, whereupon electrical connectors of the at least two battery cells are welded together. The battery module holder is in a battery extinguishing container that is open toward the top for access by a welding device and is connected via at least one extinguishing agent line to a liquid extinguishing agent reservoir for transfer of the liquid extinguishing agent from the reservoir into the battery extinguishing container.

6. 发明授权

US11021721B2 Genetically engineered Pseudomonas strains capable of metabolizing ethylene glycol and its metabolic intermediates 有权
公开(公告)号：US11021721B2
公开(公告)日：2021-06-01
申请号：US16041371
申请日：2018-07-20
申请人： Alliance for Sustainable Energy, LLC , Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen , University of Stuttgart
发明人： Gregg Tyler Beckham , Mary Ann Franden , Lahiru N. Jayakody , Nick Johannes Petrus Wierckx , Janosch Alexander Klebensberger , Lars Mathias Blank , Wing-Jin Li , Bernhard Hauer , Nicholas S. Cleveland , William E. Michener , Jason Michael Whitham
IPC分类号： C12P7/62 , C12N1/20 , C12N9/04 , C12N9/10 , C12N15/52
摘要： Presented herein are genetically engineered Pseudomonas strains capable of metabolizing ethylene glycol and producing polyhydroxyalkanoates.

7. 发明授权

US10715932B2 Active suppression of occlusion effect in hearing aid 有权
公开(公告)号：US10715932B2
公开(公告)日：2020-07-14
申请号：US16330887
申请日：2017-09-28
申请人： Rheinisch-Westfaelische-Technische Hochschule Aachen
发明人： Stefan Liebich , Carlotta Anemueller , Daniel Rueschen
IPC分类号： H04R25/00
摘要： A hearing aid for compensating for an occlusion effect while emitting an acoustic useful signal into an auditory canal of a human ear comprises an earbud that can be inserted into the auditory canal, a speaker for emitting a compensation signal into the auditory canal, a microphone for receiving an error signal from the auditory canal, and a control unit for processing a recorded signal to be emitted. The controller is designed by measuring a nominal secondary path between a speaker and the microphone and determining a transmission function that describes behavior of the nominal secondary path, determining a first requirement as a tolerance band about the transmission function, determining a second requirement as a desired sensitivity function of the hearing aid, designing the controller using an optimization method while simultaneously taking the first and second requirements into consideration, and implementing the controller in the control unit.

8. 发明授权

US09291293B2 Quick-connect hydraulic coupling socket 有权
标题翻译：快速连接液压联轴器插座
公开(公告)号：US09291293B2
公开(公告)日：2016-03-22
申请号：US13641865
申请日：2010-10-04
申请人： David Josef Ludwig Prust , Christian Loehr , Martin Inderelst
发明人： David Josef Ludwig Prust , Christian Loehr , Martin Inderelst
IPC分类号： F16L29/00 , F16L37/34 , F16L37/35 , F16L37/36
CPC分类号： F16L29/00 , F16L37/34 , F16L37/35 , F16L37/36 , Y10T137/9029
摘要： The invention relates to a hydraulic coupling bush (1), comprising a bush housing (4), in particular a sleeve-shaped hush housing (4), in which a hush tappet (12), an axially movable compression sleeve (13) that surrounds the hush tappet (12) in an axially parallel manner, in particular coaxially, and an axially movable retaining sleeve (16) that surrounds the compression sleeve (13) in an axially parallel manner, in particular coaxially, are arranged in an axially parallel manner, in particular coaxially, the outer surface of the retaining sleeve supporting or releasing securing elements (18) arranged in the bush housing (4) in the dial direction and the in particular annular end face (16a) of the retaining sleeve lying at least substantially in one plane with the end faces (12a) of the bush tappet (12) and of the bush housing (4) in the decoupled state, wherein the compression sleeve is ex posed from the inside to a hydraulic fluid to be conveyed through the bush at least substantially without applying axial force to the compression sleeve.
摘要翻译：本发明涉及一种液压联接衬套（1），其包括衬套壳体（4），特别是套筒形的安装壳体（4），其中安置挺杆（12），轴向可移动的压缩套筒（13）以轴向平行的方式（特别是同轴地）围绕嘘嘘挺杆（12），并且以轴向平行的方式（特别是同轴地）围绕压缩套筒（13）的轴向移动的保持套筒（16）被布置成轴向平行方式，特别是同轴地，保持套的外表面支撑或释放在拨盘方向上布置在衬套壳体（4）中的固定元件（18），并且特别是至少保持套筒的环形端面（16a）基本上在一个平面中，衬套挺杆（12）的端面（12a）和衬套壳体（4）处于解耦状态，其中压缩套筒从内部被提供到待传送的液压流体至少灌木丛而不会对压缩套筒施加轴向力。

9. 发明授权

US11291754B2 System for the extracorporeal elimination of carbon monoxide 有权
公开(公告)号：US11291754B2
公开(公告)日：2022-04-05
申请号：US16084129
申请日：2017-02-14
申请人： Rheinisch-Westfaelische Technische Hochschule Aachen
发明人： Jutta Arens , Ralf Borchardt , Peter Christian Schlanstein , Thomas Schmitz-Rode , Lotte Schraven , Georg Wagner , Ulrich Steinseifer
IPC分类号： A61M1/16 , A61M1/36 , A61M1/32 , A61M1/30
摘要： A system for the extracorporeal elimination of carbon monoxide, includes at least one pump and a gas exchange chamber, wherein the at least one pump can be connected to the blood circulatory system of a person by way of a first tube section connectable to a cannula and is connected to a gas exchange chamber via a second tube section, wherein the system is configured to transfer blood, via the first tube section, from the blood circulatory system of the person by way of at least one pump into the gas exchange chamber, and to return the blood from the gas exchange chamber to the blood circulatory system of the person via the same first tube section.

10. 发明授权

US10508043B2 Thermal desalination for increased distillate production 有权
公开(公告)号：US10508043B2
公开(公告)日：2019-12-17
申请号：US14576798
申请日：2014-12-19
申请人： Massachusetts Institute of Technology , Rheinisch-Westfaelische Technische Hochschule Aachen
发明人： Tawfiq Hanna Dahdah , Alexander Mitsos
IPC分类号： C02F1/06 , B01D3/00 , B01D3/06 , B01D3/14 , C02F1/04 , C02F103/08
摘要： A superstructure for thermal desalination is optimized by controlling various parameters, wherein the variable parameters include a feed routing for flow of a liquid feed; brine routings for flow of concentrated brine from the liquid feed; vapor routings for vapor generated from the liquid feed; a series of multi-effect distillation effects, each of the effects coupled with at least one routing selected from the feed routing and the brine routings and with one of the vapor routings; and a series of multi-stage flash stages coupled with at least one routing selected from the feed routing and the brine routings and with one of the vapor routings. The superstructure may or may not contain a thermal vapor compressor.

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