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1. 发明申请

US20100049227A1 Delivery Tools for Sleep Disorders Treatment Implant and Methods of Implantation 失效
标题翻译：睡眠障碍治疗植入物和植入方法的交付工具
公开(公告)号：US20100049227A1
公开(公告)日：2010-02-25
申请号：US12168820
申请日：2008-07-07
申请人： Anant V. Hegde , Kasey Kai-Chi Li , Phil Houle , Casidy Hallsten , Chris D. Owen
发明人： Anant V. Hegde , Kasey Kai-Chi Li , Phil Houle , Casidy Hallsten , Chris D. Owen
IPC分类号： A61B17/3209 , A61F5/56 , A61B17/00
CPC分类号： A61F2/00 , A61B17/320016 , A61B17/3209 , A61B2017/248 , A61F5/56
摘要： Methods and tools are disclosed for inserting an implant device that treats snoring and apnea of a patient by altering the position of a soft palate. Methods and tools can make an incision in patient's soft and hard palate to create a cavity that can house the implant. The tools can have visually observable markings that can be aligned with the incision, thus controlling the depth of the cavity. A needle having an incision edge can be used to make an incision in patient's soft palate. The needle can be bent into a suitable longitudinal shape to allow easier access and visualization of the process. A blade that makes the cavity in the tissue can be housed inside a channel in the needle. The tools may have stoppers to prevent excessive extension and retraction of the blade thus preventing an excessive cavity depth. Some tools may also house the implant device, which may be implanted after the cavity is formed.
摘要翻译：公开了用于插入通过改变软腭的位置来治疗患者的打鼾和呼吸暂停的植入装置的方法和工具。方法和工具可以在病人的柔软和硬腭中形成切口，以创建可容纳植入物的腔体。工具可以具有可与切口对准的视觉上可观察到的标记，从而控制腔的深度。具有切口边缘的针可用于在患者的软腭中进行切口。针可以弯曲成适当的纵向形状，以允许更容易地进入和可视化过程。使得组织中的空腔可以容纳在针的通道内的刀片。工具可以具有止动件以防止叶片的过度的伸展和缩回，从而防止过大的腔深度。一些工具还可以容纳植入装置，其可以在腔形成之后植入。

2. 发明申请

US20090078273A1 Smart Mandibular Repositioning System 有权
标题翻译：智能下颌重建系统
公开(公告)号：US20090078273A1
公开(公告)日：2009-03-26
申请号：US12235531
申请日：2008-09-22
申请人： Nikhil D. Bhat , Anant V. Hegde , Charisse M. Yung , George Y. Choi
发明人： Nikhil D. Bhat , Anant V. Hegde , Charisse M. Yung , George Y. Choi
IPC分类号： A61F5/56
CPC分类号： A61B5/4818 , A61B5/0031 , A61B5/076 , A61B5/1076 , A61B5/682 , A61F2/02 , A61F5/566
摘要： Systems and methods for detecting an obstructive sleep apnea event are disclosed herein. The systems and methods may use an electrical output generating ionic polymer metal composite sensor attached to a region in an airway passage in an oral cavity. The electrical output may be wirelessly transmitted as a signal for indication of an obstructive sleep apnea event. The signal may be further processed by a smart mandibular repositioning system for treatment of the obstructive sleep apnea event.
摘要翻译：本文公开了用于检测阻塞性睡眠呼吸暂停事件的系统和方法。系统和方法可以使用附着在口腔中的气道通道中的区域的电输出产生离子聚合物金属复合传感器。电输出可以作为用于指示阻塞性睡眠呼吸暂停事件的信号被无线发送。该信号可以由用于治疗阻塞性睡眠呼吸暂停事件的智能下颌骨重新定位系统进一步处理。

3. 发明申请

US20080041398A1 Tongue Stabilization Device and Methods of Using the Same 有权
标题翻译：舌稳定装置及其使用方法
公开(公告)号：US20080041398A1
公开(公告)日：2008-02-21
申请号：US11847271
申请日：2007-08-29
申请人： Anant Hegde , Kasey Li , Nikhil Bhat , Christopher Bagley , Casidy Hallsten , George Choi , Doyeon Kim
发明人： Anant Hegde , Kasey Li , Nikhil Bhat , Christopher Bagley , Casidy Hallsten , George Choi , Doyeon Kim
IPC分类号： A61F5/56
CPC分类号： A61F5/56 , A61B2017/248 , A61F5/566 , A61F2210/0038 , Y10S602/902
摘要： An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods of using the device are also disclosed. The implant is an implant for stabilizing the tongue, the implant having an anchoring portion for securing a first end of the implant with the mandibula; a control portion connected with the anchoring portion, configured for selectively activating the implant; a flexible portion connected at its proximal end with the control portion, where the flexible portion has three-dimensional flexibility in a first state and where the flexible portion has a lesser three-dimensional flexibility in a second state, and where the flexible portion is selectively switchable between the first and second state by the control portion; an anchoring portion for connecting the implant with the base of the tongue connected with the flexible portion, and a latch mechanism coupled with the control portion and configured to maintain the flexible portion in either of the first and second states. Methods of treating airway disorders such as sleep apnea and snoring with the airway implant device are disclosed herein.
摘要翻译：公开了一种用于在空气通道中保持和/或形成开口的气道植入装置。还公开了使用该装置的方法。植入物是用于稳定舌头的植入物，所述植入物具有用于固定植入物的第一端与下颌骨的锚定部分; 与所述锚定部分连接的控制部分，被配置为选择性地启动所述植入物; 其柔性部分在其近端连接有控制部分，其中柔性部分在第一状态下具有三维柔性，并且柔性部分在第二状态下具有较小的三维柔性，并且其中柔性部分是选择性的通过控制部在第一状态和第二状态之间切换; 用于将植入物与与柔性部分连接的舌片的基部连接的锚定部分，以及与控制部分联接并被配置为将柔性部分保持在第一状态和第二状态中的任一状态的闩锁机构。本文公开了用气道植入装置处理呼吸道疾病如睡眠呼吸暂停和打鼾的方法。

4. 发明授权

US07909037B2 Tethered airway implants and methods of using the same 有权
标题翻译：束缚气道植入物及其使用方法
公开(公告)号：US07909037B2
公开(公告)日：2011-03-22
申请号：US11737107
申请日：2007-04-18
申请人： Anant V. Hegde , Kasey Kai-Chi Li , Nikhil D. Bhat , Doyeon Kim , George Y. Choi
发明人： Anant V. Hegde , Kasey Kai-Chi Li , Nikhil D. Bhat , Doyeon Kim , George Y. Choi
IPC分类号： A61F5/56 , A61F13/00 , A61F5/04 , A61F2/30 , A61F2/00 , A61B19/00 , A61B17/56 , A61B17/58 , A61B17/70
CPC分类号： A61F5/56 , A61B2017/248 , A61F5/566 , G02B26/0841 , H02N1/008 , Y10S602/902
摘要： An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods of using the device are also disclosed. The airway implant device includes a deformable element to control the opening of an air passageway and a tether. Preferably the deformable element is an electroactive polymer element. Energizing of the electroactive polymer element provides support for the walls of an air passageway, when the walls collapse, and thus, completely or partially opens the air passageway. Also disclosed is an implant for stabilizing the tongue, the implant having an anchoring portion for securing a first end of the implant with the mandibula; a control portion connected with the anchoring portion, configured for selectively activating the implant; a flexible portion connected at its proximal end with the control portion, where the flexible portion has three-dimensional flexibility in a first state and where the flexible portion has a lesser three-dimensional flexibility in a second state, and where the flexible portion is selectively switchable between the first and second state by the control portion; and an anchoring portion for connecting the implant with the base of the tongue connected with the distal end of the flexible portion. Methods of treating airway disorders such as sleep apnea and snoring with the airway implant device are disclosed herein.
摘要翻译：公开了一种用于在空气通道中保持和/或形成开口的气道植入装置。还公开了使用该装置的方法。气道植入装置包括可变形元件以控制空气通道和系绳的开口。优选地，可变形元件是电活性聚合物元件。电活性聚合物元件的通电为空气通道的壁提供支撑，当壁崩溃时，从而完全或部分地打开空气通道。还公开了一种用于稳定舌头的植入物，植入物具有用于固定植入物的第一端与下颌骨的锚固部分; 与所述锚定部分连接的控制部分，被配置为选择性地启动所述植入物; 其柔性部分在其近端连接有控制部分，其中柔性部分在第一状态下具有三维柔性，并且柔性部分在第二状态下具有较小的三维柔性，并且其中柔性部分是选择性的通过控制部在第一状态和第二状态之间切换; 以及用于将植入物与与柔性部分的远端连接的舌头的基部连接的锚固部分。本文公开了用气道植入装置处理呼吸道疾病如睡眠呼吸暂停和打鼾的方法。

5. 发明申请

US20100004659A1 Cavitation Depth, Perforation Confirmation and Implant Delivery Tool 有权
标题翻译：气蚀深度，穿孔确认和植入物交付工具
公开(公告)号：US20100004659A1
公开(公告)日：2010-01-07
申请号：US12168825
申请日：2008-07-07
申请人： Anant V. Hegde , Adrian McVicker , Jerry Sung Woo Choe , James B. Ross
发明人： Anant V. Hegde , Adrian McVicker , Jerry Sung Woo Choe , James B. Ross
IPC分类号： A61B17/58 , A61F5/56 , A61F13/20
CPC分类号： A61F5/566
摘要： Methods and tools that insert implants for the treatment of snoring and sleep apnea in a cavity created in the patient's tissue are disclosed. Some tools and methods can additionally verify that the cavity has proper cavitation depth and does not have unwanted perforations. The tools include: a sheath having a substantially flat portion for housing an implant, the sheath having a distal end and a proximal end, the sheath having a hollow collar on the proximal end, an insertion depth mark near the distal end, and a slit on the distal end, the slit being in fluid communication with the hollow collar; a substantially rigid pusher configured to be disposed within and in slidable engagement with the sheath, the pusher having a distal end and a proximal end, the pusher having a rigid body having an outside diameter for slidably engaging with the hollow collar of the sheath, a tip on the distal end for engaging a proximal end of an implant, and a lumen extending from said proximal side to said distal side of said rigid body, the lumen configured for fluid communication with a syringe at the proximal end and in fluid communication with the sheath at the distal end.
摘要翻译：公开了在患者组织中产生的腔中插入用于治疗打鼾和睡眠呼吸暂停的植入物的方法和工具。一些工具和方法可以另外验证空腔具有适当的空化深度并且不具有不需要的穿孔。所述工具包括：护套，其具有用于容纳植入物的基本上平坦的部分，所述护套具有远端和近端，护套在近端具有中空的环，在远端附近具有插入深度标记，在所述远端处，所述狭缝与所述中空轴环流体连通; 一个基本上刚性的推动器，其构造成设置在护套内并与护套滑动接合，该推动器具有远端和近端，该推动器具有刚体，该刚体具有用于与护套的空心环滑动接合的外径，在远端上的尖端用于接合植入物的近端，以及从所述刚体的所述近侧延伸到所述远端侧的内腔，所述内腔构造成用于在近端处与注射器流体连通并且与所述近端流体连通护套在远端。

6. 发明申请

US20090069866A1 IMPLANT TESTER 审中-公开
标题翻译：植入物检测仪
公开(公告)号：US20090069866A1
公开(公告)日：2009-03-12
申请号：US12205625
申请日：2008-09-05
申请人： John Michael Farbarik , John C. Potosky , Anant V. Hegde , Casidy Domingo , Charisse M. Yung , Nikhil D. Bhat , George Yoseung Choi
发明人： John Michael Farbarik , John C. Potosky , Anant V. Hegde , Casidy Domingo , Charisse M. Yung , Nikhil D. Bhat , George Yoseung Choi
IPC分类号： A61N1/08
CPC分类号： A61B5/06 , A61B5/0031 , A61B5/076 , A61B5/682 , A61B5/6882 , A61F2/02 , A61F5/56 , G01V15/00
摘要： An implant testing device and a method of detecting an airway implant are disclosed. The testing device detects the presence of the implant within a patient's body and can be used to determine its location. The testing device also provides an indication of proper function of the implant electronics. A detector circuit of the testing device generates an output signal representative of proximity of the airway implant. A processing circuit receives the output signal and determines proximity of the implant based on one or more detection thresholds. The processing circuit also provides a visual and/or audible alert. In some embodiments, the processing circuit varies the flash rate of one or more light emitting diodes and/or the pitch of an alert tone based on proximity of the implant. Various embodiments of the testing device are adapted for handheld use and can include a handle, elongated portion, and detector element.
摘要翻译：公开了一种植入物测试装置和一种检测气道植入物的方法。测试装置检测植入物在患者体内的存在并且可用于确定其位置。测试装置还提供植入电子器件的正常功能的指示。测试装置的检测器电路产生表示气道植入物接近的输出信号。处理电路接收输出信号并且基于一个或多个检测阈值确定植入物的接近度。处理电路还提供视觉和/或听觉警报。在一些实施例中，处理电路基于植入物的接近度改变一个或多个发光二极管的闪光速率和/或警报音调的音调。测试装置的各种实施例适用于手持使用，并且可以包括手柄，细长部分和检测器元件。

7. 发明授权

US07909038B2 Tongue stabilization device and methods of using the same 有权
标题翻译：舌稳定装置及其使用方法
公开(公告)号：US07909038B2
公开(公告)日：2011-03-22
申请号：US11847271
申请日：2007-08-29
申请人： Anant V. Hegde , Kasey Kai-Chi Li , Nikhil D. Bhat , Christopher Bagley , Casidy Hallsten , George Y. Choi , Doyeon Kim
发明人： Anant V. Hegde , Kasey Kai-Chi Li , Nikhil D. Bhat , Christopher Bagley , Casidy Hallsten , George Y. Choi , Doyeon Kim
IPC分类号： A61F5/56 , F16F1/00 , F16F9/00 , A61J7/00 , A61M31/00 , A61M37/00 , A61M5/20
CPC分类号： A61F5/56 , A61B2017/248 , A61F5/566 , A61F2210/0038 , Y10S602/902
摘要： An airway implant device for maintaining and/or creating an opening in air passageways is disclosed. Methods of using the device are also disclosed. The implant is an implant for stabilizing the tongue, the implant having an anchoring portion for securing a first end of the implant with the mandibula; a control portion connected with the anchoring portion, configured for selectively activating the implant; a flexible portion connected at its proximal end with the control portion, where the flexible portion has three-dimensional flexibility in a first state and where the flexible portion has a lesser three-dimensional flexibility in a second state, and where the flexible portion is selectively switchable between the first and second state by the control portion; an anchoring portion for connecting the implant with the base of the tongue connected with the flexible portion, and a latch mechanism coupled with the control portion and configured to maintain the flexible portion in either of the first and second states. Methods of treating airway disorders such as sleep apnea and snoring with the airway implant device are disclosed herein.
摘要翻译：公开了一种用于在空气通道中保持和/或形成开口的气道植入装置。还公开了使用该装置的方法。植入物是用于稳定舌头的植入物，所述植入物具有用于固定植入物的第一端与下颌骨的锚定部分; 与所述锚定部分连接的控制部分，被配置为选择性地启动所述植入物; 其柔性部分在其近端连接有控制部分，其中柔性部分在第一状态下具有三维柔性，并且柔性部分在第二状态下具有较小的三维柔性，并且其中柔性部分是选择性的通过控制部在第一状态和第二状态之间切换; 用于将植入物与与柔性部分连接的舌片的基部连接的锚定部分，以及与控制部分联接并被配置为将柔性部分保持在第一状态和第二状态中的任一状态的闩锁机构。本文公开了用气道植入装置处理呼吸道疾病如睡眠呼吸暂停和打鼾的方法。

8. 发明申请

US20100319711A1 AIRWAY IMPLANT AND METHODS OF MAKING AND USING 审中-公开
公开(公告)号：US20100319711A1
公开(公告)日：2010-12-23
申请号：US12821912
申请日：2010-06-23
申请人： Anant V. Hegde , George S. Choi , Wally S. Buch
发明人： Anant V. Hegde , George S. Choi , Wally S. Buch
IPC分类号： A61F5/56
CPC分类号： A61L31/125 , A61B2017/248 , A61C7/00 , A61F2/00 , A61F5/56 , A61F5/566 , A61F2210/0023 , A61L31/14 , A61N1/0517 , A61N1/0519 , A61N1/0548 , A61N1/3601 , Y10S602/902
摘要： A system and device for maintaining and/or creating patency in airways is disclosed. The methods of using the system and device are also disclosed. The system includes a power source that energizes a electro-active polymer implant. The energized polymer implant provides stiffness and shape to the airway, thereby minimizing collapse or deformation of the airway. A method of making the device is also disclosed.
摘要翻译：公开了一种用于在气道中维持和/或产生通畅的系统和装置。还公开了使用该系统和装置的方法。该系统包括为电活性聚合物植入物通电的电源。通电的聚合物植入物为气道提供刚度和形状，从而最小化气道的塌陷或变形。还公开了制造该器件的方法。

9. 发明申请

US20100198305A1 DETECTION OF IMPLANT FUNCTIONALITY 审中-公开
标题翻译：检测植入功能
公开(公告)号：US20100198305A1
公开(公告)日：2010-08-05
申请号：US12696463
申请日：2010-01-29
申请人： John Michael Farbarik
发明人： John Michael Farbarik
IPC分类号： A61N1/08
CPC分类号： A61N1/08
摘要： Techniques are disclosed for detecting a functionality of a medical device implanted within the human body. A testing method includes delivering power to and measuring an electrical response of ion exchange polymer metal composite (IPMC) material that is part of the implant device in a first testing interval. Power can be transmitted at radio frequencies which penetrate tissue such that direct contact with the implant device is not required. Following the first testing interval, the implant can be powered continuously for a predetermined time. The implant can be powered in a second testing interval and the electrical response can again be measured. A functionality of the implant device can be detected based on the electrical response in the first and second testing intervals. The testing method can be practiced in connection with a handheld device, a retainer, or other suitable apparatus.
摘要翻译：公开了用于检测植入人体内的医疗装置的功能的技术。测试方法包括在第一测试间隔内向植入装置输送功率并测量离子交换聚合物金属复合材料（IPMC）材料的电响应。功率可以在穿透组织的射频发射，从而不需要与植入装置的直接接触。在第一个测试间隔之后，植入物可以连续供电预定的时间。植入物可以在第二个测试间隔内供电，并且可以再次测量电响应。可以基于第一和第二测试间隔中的电响应来检测植入装置的功能。测试方法可以与手持设备，保持器或其它合适的设备结合使用。

10. 发明申请

US20090173351A1 CONTROL SYSTEM FOR A TONGUE STABILIZATION DEVICE 审中-公开
标题翻译：用于稳定稳定装置的控制系统
公开(公告)号：US20090173351A1
公开(公告)日：2009-07-09
申请号：US12250398
申请日：2008-10-13
申请人： Koray Sahin , Anant V. Hegde , Kasey Kai-Chi Li , Nikhil D. Bhat , Christopher Bagley , Casidy Domingo , John M. Farbarik , George Y. Choi , Doyeon Kim
发明人： Koray Sahin , Anant V. Hegde , Kasey Kai-Chi Li , Nikhil D. Bhat , Christopher Bagley , Casidy Domingo , John M. Farbarik , George Y. Choi , Doyeon Kim
IPC分类号： A61F5/56 , G06F19/00
CPC分类号： A61F2/02 , A61B2017/248 , A61F5/56 , A61F5/566 , A61F2210/0038
摘要： A tongue implant control system and methods for stabilizing the tongue are disclosed. The tongue implant control system includes an implant device and a non-implanted control device in wireless communication. The control device provides an inductive power transfer for operating the implant device. The control device also sends commands for changing a state of the implant device. The implant device includes a flexible portion for attachment to the tongue and to one or more actuators. The one or more actuators may include shape memory material. The implant device detects a command from the control device and powers an actuator based on the command. Optionally, the implant device communicates its operating state to the control device and the control device displays information about the implant device at a user interface.
摘要翻译：公开了一种舌植入物控制系统和用于稳定舌头的方法。舌植入物控制系统包括无线通信中的植入装置和非植入式控制装置。控制装置提供用于操作植入装置的感应功率传递。控制装置还发送用于改变植入装置的状态的命令。植入装置包括用于附接到舌头和一个或多个致动器的柔性部分。一个或多个致动器可以包括形状记忆材料。植入装置根据该命令检测来自控制装置的命令并对致动器供电。可选地，植入装置将其操作状态传达到控制装置，并且控制装置在用户界面处显示关于植入装置的信息。

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