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1. 发明申请

US20180220964A1 BIOLOGICAL INFORMATION MEASURING INSTRUMENT 审中-公开
公开(公告)号：US20180220964A1
公开(公告)日：2018-08-09
申请号：US15750952
申请日：2016-08-05
申请人： SHARP KABUSHIKI KAISHA , OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION
发明人： HIROSHI SAKAYA , TETSUYA HAYASHI , AZUSA NAKANO , SHUNSUKE SHIMAMURA , TERUMASA SHIMADA
IPC分类号： A61B5/00 , A61B5/0408 , A61B5/0428
CPC分类号： A61B5/6831 , A61B5/0408 , A61B5/04286 , A61B5/4872 , A61B5/6823 , A61B2503/40 , A61B2562/0209 , A61D13/00
摘要： A wearable instrument is provided that measures biological information over an extended period of time by enabling an electrode to be readily pressed to an axilla of an animal. The wearable instrument includes: electrodes to be placed under the left and right axillae of a dog to produce an electrocardiogram; pull-up straps to be placed in direct contact with the axilla to press the electrodes onto the axilla; and a cinch strap placed across the anterior chest of the dog to draw the left and right sections of the pull-up strap together.

2. 发明授权

US11155775B2 Cell culture vessel and sample cell for observation use 有权
公开(公告)号：US11155775B2
公开(公告)日：2021-10-26
申请号：US15779951
申请日：2016-11-07
申请人： OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION , NATIONAL UNIVERSITY CORPORATION KYUSHU INSTITUTE OF TECHNOLOGY
发明人： Masaya Hagiwara , Tomohiro Kawahara
IPC分类号： C12M1/00 , C12M1/12
摘要： The present invention provides a cell culture vessel or a sample cell for observation use that makes it possible to observe three-dimensionally-cultured cells from various angles. The cell culture vessel or the sample cell for observation use according to the present invention is characterized by being equipped with a culture gel in which a cell or cell tissue is embedded and a first vessel which encloses the culture gel, wherein a space in the first vessel is filled with the culture gel; and the first vessel has a light-permeable window made from a hydrogel.

3. 发明授权

US10208246B2 Method for manufacturing alkali halide-based scintillator powder and method for manufacturing scintillator material 有权
公开(公告)号：US10208246B2
公开(公告)日：2019-02-19
申请号：US14901496
申请日：2014-10-21
申请人： OSAKA PREFECTURE UNIVERSITY Public Corporation , YASU MEDICAL IMAGING TECHNOLOGY CO., LTD.
发明人： Taketoshi Kawai , Fumiaki Kunimoto
IPC分类号： C09K11/62 , B32B37/10 , C09K11/61
摘要： An additive containing an ion as a luminescence center is added to alkali halide powder as a base material. Mechanical energy for applying an impact force, a shearing force, a shear stress, or a friction force is applied so as to grind or mix the alkali halide powder and the additive. The ion as the luminescence center is doped into the alkali halide as the base material so as to obtain alkali halide-based scintillator powder. With this process, the alkali halide-based scintillator powder can be manufactured at a room temperature in the atmospheric air without any complicated condition control or any process at a high temperature under high vacuum and a large-sized scintillator sheet can be produced.

4. 发明授权

US09797842B2 Device and method utilizing a metallic nanoparticle assembly structure for detecting a target substance 有权
公开(公告)号：US09797842B2
公开(公告)日：2017-10-24
申请号：US13992475
申请日：2011-12-08
申请人： Shiho Tokonami , Takuya Iida , Yojiro Yamamoto , Hiroshi Shiigi , Tsutomu Nagaoka
发明人： Shiho Tokonami , Takuya Iida , Yojiro Yamamoto , Hiroshi Shiigi , Tsutomu Nagaoka
IPC分类号： G01N21/65 , G01N21/552 , G01N33/543
CPC分类号： G01N21/658 , G01N21/554 , G01N33/54346
摘要： Disclosed is a device and method allowing a trace amount of a target substance to be detected. A metallic nanoparticle assembly structure is formed of metallic nanoparticles assembled together and modified with a host molecule allowing the target substance to specifically adhere thereto. A metallic nanorod is modified with a host molecule allowing the target substance to specifically adhere thereto. The metallic nanorod is conjugated to the metallic nanoparticle assembly structure by the target substance. An extinction spectrum of localized surface plasmon resonance or a surface enhanced Raman scattering (SERS) spectrum induced in the metallic nanoparticle assembly structure and the metallic nanostructure is measured with a spectroscope. The target substance is detected based on that spectrum.

5. 发明授权

US09512534B2 Copper filling-up method 有权
标题翻译：铜填充法
公开(公告)号：US09512534B2
公开(公告)日：2016-12-06
申请号：US13974113
申请日：2013-08-23
申请人： OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION , NITTO BOSEKI CO., LTD.
发明人： Kazuo Kondo , Takeyasu Saito , Naoki Okamoto , Masaru Bunya , Minoru Takeuchi
IPC分类号： C25D5/18 , H01L21/768 , C25D3/38 , H01L21/288
CPC分类号： C25D5/18 , C25D3/38 , H01L21/2885 , H01L21/76861 , H01L21/76877 , H01L21/76898
摘要： There is provided a method of well filling copper in a conductivity-rendered non-through hole having an aspect ratio (depth/hole diameter) of 5 or more on a substrate in a short period of time, and the method comprises using an acidic copper plating bath comprising a water-soluble copper salt, sulfuric acid, chlorine ion, a brightener and a copolymer of diallylamines and sulfur dioxide and filling copper in the non-through hole by periodic current reversal copper plating.
摘要翻译：提供了一种在短时间内在衬底上具有5或更大的纵横比（深度/孔直径）的导电性非贯通孔中充满铜的方法，该方法包括使用酸性铜包含水溶性铜盐，硫酸，氯离子，增白剂和二烯丙基胺和二氧化硫的共聚物的电镀浴，并通过周期性电流反转铜电镀在非贯通孔中填充铜。

6. 发明授权

US09371574B2 Ni3(Si, Ti)-based intermetallic compound to which W is added, and method for producing same 有权
标题翻译：添加W的Ni3（Si，Ti）系金属间化合物及其制造方法
公开(公告)号：US09371574B2
公开(公告)日：2016-06-21
申请号：US13395773
申请日：2010-09-14
申请人： Yasuyuki Kaneno , Takayuki Takasugi
发明人： Yasuyuki Kaneno , Takayuki Takasugi
IPC分类号： C22F1/10 , C22C19/03
CPC分类号： C22F1/10 , C22C19/03 , Y10T428/12
摘要： The present invention provides a structural material having enhanced ductility characteristics at high temperatures and enhanced strength characteristics. The present invention provides an Ni3(Si, Ti)-based intermetallic compound characterized by containing from 25 to 500 ppm by weight of B with respect to a weight of an intermetallic compound having a composition of 100% by atom in total consisting of Ni as a main component, from 7.5 to 12.5% by atom of Si, from 4.5 to 11.5% by atom of Ti and from 0.5 to 5.0% by atom of W.
摘要翻译：本发明提供了一种在高温下具有增强的延展性特征和增强的强度特性的结构材料。本发明提供了一种Ni3（Si，Ti）基金属间化合物，其特征在于，相对于总计100重量％的组成为金属间化合物的重量，含有25〜500重量ppm的B，由Ni作为主要成分为硅原子为7.5〜12.5原子％，Ti为4.5〜11.5原子％，W为0.5〜5.0原子％

7. 发明申请

US20160123968A1 DEVICE AND METHOD FOR DETECTING AN ANALYTE 有权
标题翻译：用于检测分析仪的装置和方法
公开(公告)号：US20160123968A1
公开(公告)日：2016-05-05
申请号：US14894452
申请日：2014-05-30
申请人： OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION
发明人： Takuya IIDA , Shiho TOKONAMI
IPC分类号： G01N33/543 , G01N21/21 , G01N21/65 , G01N33/553 , G01N33/53
CPC分类号： G01N33/54346 , C12Q1/6834 , C12Q2563/155 , C12Q2565/628 , G01N21/21 , G01N21/554 , G01N21/658 , G01N33/5308 , G01N33/553 , G01N2201/061 , G01N2201/0683
摘要： A detection device detects an analyte that may be contained in a specimen. The detection device includes a plurality of gold nanoparticles, an optical trapping light source, an illumination light source, an objective lens, an image pick-up device, and a computation unit. The plurality of gold nanoparticles are each modified with a probe DNA allowing the analyte to specifically adhere thereto. The optical trapping light source emits polarized light for assembling the plurality of gold nanoparticles together. The objective lens focuses and introduces the polarized light into a liquid containing a specimen and the plurality of gold nanoparticles. The image pick-up device receives light from the liquid. The computation unit detects an analyte based on a signal received from the image pick-up device.
摘要翻译：检测装置检测可能包含在样本中的分析物。检测装置包括多个金纳米颗粒，光学捕获光源，照明光源，物镜，图像拾取装置和计算单元。多个金纳米颗粒各自用探针DNA修饰，允许分析物特异性地粘附于其上。光捕获光源发射用于将多个金纳米颗粒组装在一起的偏振光。物镜聚焦并将偏振光引入含有样品和多个金纳米颗粒的液体中。摄像装置接收来自液体的光。计算单元基于从图像拾取装置接收的信号检测分析物。

8. 发明申请

US20150368655A1 TRANSFORMED EUGLENA AND PROCESS FOR PRODUCING SAME 审中-公开
标题翻译：变形EUGLENA及其生产方法
公开(公告)号：US20150368655A1
公开(公告)日：2015-12-24
申请号：US14655228
申请日：2013-12-25
申请人： OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION , euglena Co., Ltd.
发明人： Masami Nakazawa , Daiki Haruguchi , Mitsuhiro Ueda , Kazutaka Miyatake
IPC分类号： C12N15/79
CPC分类号： C12N15/79 , C12N15/8205 , C12N15/8209
摘要： A Euglena carrying a foreign gene of interest in an expressible manner is provided.A Euglena carrying a drug resistance gene and a foreign gene of interest in an expressible manner.
摘要翻译：提供以可表达的方式携带感兴趣的外来基因的Euglena。以可表达的方式携带耐药性基因和感兴趣的外源基因的Euglena。

9. 发明授权

US09206461B2 Microorganism detection sensor and method of manufacturing the same 有权
标题翻译：微生物检测传感器及其制造方法
公开(公告)号：US09206461B2
公开(公告)日：2015-12-08
申请号：US14003613
申请日：2012-03-06
申请人： Shiho Tokonami , Hiroshi Shiigi , Tsutomu Nagaoka , Mugihei Ikemizu , Mari Takahashi
发明人： Shiho Tokonami , Hiroshi Shiigi , Tsutomu Nagaoka , Mugihei Ikemizu , Mari Takahashi
IPC分类号： C12Q1/04 , G01N33/569 , G01N33/543 , C25D5/00
CPC分类号： C12Q1/04 , C25D5/00 , G01N33/5438 , G01N33/569 , Y10T428/24479
摘要： The present invention provides a sensor including a detection unit having a detection electrode and a polymer layer that is disposed on the detection electrode and includes a mold having a three-dimensional structure complementary to a steric structure of a microorganism to be detected. The sensor detects the microorganism based on a state of capturing the microorganism in the mold. The polymer layer is formed by a manufacturing method including: a polymerization step of polymerizing a monomer in the presence of the microorganism to be detected, to form the polymer layer having captured the microorganism on the detection electrode; a destruction step of partially destroying the microorganism captured in the polymer layer; and a peroxidation step of peroxidizing the polymer layer to release the microorganism from the polymer layer.
摘要翻译：本发明提供了一种传感器，其包括具有检测电极和聚合物层的检测单元，该检测单元设置在检测电极上，并且包括具有与待检测微生物的空间结构互补的三维结构的模具。传感器基于在模具中捕获微生物的状态来检测微生物。聚合物层是通过以下制造方法形成的：包括：在待检测微生物存在下聚合单体的聚合步骤，以形成在检测电极上捕获微生物的聚合物层; 部分破坏在聚合物层中捕获的微生物的破坏步骤; 以及使聚合物层过氧化以从聚合物层中释放微生物的过氧化步骤。

10. 发明授权

US09173634B2 Fatty tissue image display device 有权
标题翻译：脂肪组织图像显示装置
公开(公告)号：US09173634B2
公开(公告)日：2015-11-03
申请号：US13637999
申请日：2011-03-25
申请人： Toshiyuki Matsunaka , Hiromichi Horinaka , Hiroyasu Morikawa , Tomohiro Ogawa
发明人： Toshiyuki Matsunaka , Hiromichi Horinaka , Hiroyasu Morikawa , Tomohiro Ogawa
IPC分类号： A61B8/08 , A61B5/00 , A61B8/14
CPC分类号： A61B8/0858 , A61B5/4872 , A61B8/14 , A61B8/5223
摘要： A fatty tissue image display device includes a light source, an ultrasonic wave transmission/reception mechanism, an analysis unit which calculates a velocity change of ultrasonic waves after irradiation with a heating beam as compared to before irradiation with light, a display control unit which displays the distribution of the calculated velocity change of the ultrasonic waves, a designation unit which waits for the designation of a region of interest, a histogram calculation unit which, based on luminance information or color information within the designated region of interest, calculates the histograms of a fatty region showing a negative velocity change of the ultrasonic waves and a normal region showing a positive velocity change of the ultrasonic waves, and an index calculation unit which, from the calculated histograms of the fatty and normal regions, calculates a fatty change index that is an index of a proportion of fatty tissue.
摘要翻译：脂肪组织图像显示装置包括光源，超声波发送/接收机构，分析单元，其计算与用光照射之前的加热束照射之后的超声波的速度变化;显示控制单元，其显示计算超声波的速度变化的分布，等待感兴趣区域的指定的指定单元，基于指定的感兴趣区域内的亮度信息或颜色信息的直方图计算单元计算直方图示出超声波的负速度变化的脂肪区域和表示超声波的正速度变化的正常区域，以及指标计算单元，根据计算出的脂肪和正常区域的直方图，计算脂肪变化指数，是脂肪组织比例的指标。

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