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1. 发明授权

US10675718B2 Method and device for reversibly attaching a phase changing metal to an object 有权
公开(公告)号：US10675718B2
公开(公告)日：2020-06-09
申请号：US15428786
申请日：2017-02-09
申请人： MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
发明人： Zhou Ye , Guo Zhan Lum , Metin Sitti
IPC分类号： B23K1/00 , B23K35/26 , B23K35/00
摘要： A method for reversibly attaching a phase changing metal to an object, the method comprising the steps of: providing a substrate having at least one surface at which the phase changing metal is attached, heating the phase changing metal above a phase changing temperature at which the phase changing metal changes its phase from solid to liquid, bringing the phase changing metal, when the phase changing metal is in the liquid phase or before the phase changing metal is brought into the liquid phase, into contact with the object, permitting the phase changing metal to cool below the phase changing temperature, whereby the phase changing metal becomes solid and the object and the phase changing metal become attached to each other, reheating the phase changing metal above the phase changing temperature to liquefy the phase changing metal, and removing the substrate from the object, with the phase changing metal separating from the object and remaining with the substrate.

2. 发明授权

US10365289B2 Sensor peptide and methods of use thereof to identify substances that modulate gibberellic acid action 有权
公开(公告)号：US10365289B2
公开(公告)日：2019-07-30
申请号：US15117817
申请日：2015-02-16
申请人： Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V.
发明人： Ignacio Rubio Somoza , Michael Sauer , Detlef Weigel
IPC分类号： C12R1/865 , G01N33/50 , G01N33/58 , G01N33/74 , C07K14/415 , G01N33/566
摘要： The present invention relates to methods of identifying substances that modulate GA action through targeting its receptor or acting as a GA functional analog, sensor peptides especially designed for that methods as well as a strain of the species Saccharomyces cerevisiae expressing such a sensor peptide.

3. 发明授权

US09880168B2 Biomarker for the prediction of responsiveness to an anti-tumour necrosis factor alpha (TNF) treatment 有权
公开(公告)号：US09880168B2
公开(公告)日：2018-01-30
申请号：US14318366
申请日：2014-06-27
申请人： Max-Planck Gesellschaft zur Förderung der Wissenschaften e. V.
发明人： Zoltán Konthur , Hans Lehrach , Karl Skriner
IPC分类号： A61K39/395 , G01N33/573 , G01N33/68 , G01N33/564
CPC分类号： G01N33/573 , G01N33/564 , G01N33/68 , G01N33/6854 , G01N33/6863 , G01N2333/47 , G01N2333/4703 , G01N2333/705 , G01N2333/82 , G01N2333/91171 , G01N2333/91205 , G01N2333/9121 , G01N2333/916 , G01N2333/99 , G01N2800/10 , G01N2800/102 , G01N2800/52
摘要： The invention refers to a method for diagnosing an individual who is to be subjected to or is being subjected to an anti-tumor necrosis factor alpha (TNFα or TNF) treatment to asses the responsiveness to an anti-TNF treatment which comprises the detection of immunoglobulin(s) against one or more biomarker proteins in a bodily fluid or an excrement of said patient, and sorting the individual into one of two categories based on detection of said immunoglobulin(s), wherein individuals are classified as NON-responder or responder. The invention refers to diagnostic kits comprising said one or more biomarker proteins and the use of these kits for assessing the responsiveness to an anti-TNF treatment of an individual who is to be subjected to or is being subjected to an anti-TNFα treatment.

4. 发明申请

US20170029278A1 PROCESS FOR PREPARING SINGLE WALL CARBON NANOTUBES OF PRE-DEFINED CHIRALITY 审中-公开
标题翻译：制备单壁碳纳米管预先定义的方法
公开(公告)号：US20170029278A1
公开(公告)日：2017-02-02
申请号：US15303139
申请日：2015-04-14
申请人： Max-Planck-Gesellschaft, Zur Förderung der Wissenschaften e.V. , EMPA - Eidgenössische Materialprüfungs- und Forschungsanstalt
发明人： Roman FASEL , Pascal RUFFIEUX , Juan Ramon SANCHEZ VALENCIA , Martin JANSEN , Andreas MÜLLER , Konstantin AMSHAROV
IPC分类号： C01B31/02 , C23C16/44 , C07C15/20 , C23C16/26 , B01J23/42 , C07C13/62
CPC分类号： C23C16/44 , B01J23/42 , B82Y30/00 , B82Y40/00 , C01B32/16 , C01B32/162 , C01B2202/02 , C07C13/62 , C07C15/20 , C07C2603/54 , C23C16/26 , Y10S977/75 , Y10S977/843
摘要： The present invention relates to a process for preparing single wall carbon nanotubes (SWCNT) having a diameter dSWCNT, which comprises (i) providing a precursor element which comprises a segment SSWCNT of the single wall carbon nanotube, the segment SSWCNT being made of at least one ring formed by ortho-fused benzene rings, and having a first end E1 which is open and a second end E2 which is opposite to the first end E1, (ii) growing the precursor element by vapour phase reaction with a carbon-source compound on the surface of a metal-containing catalyst, wherein the precursor element is in contact with the surface of the metal-containing catalyst via the open end E1 of the segment SSWCNT, and the metal-containing catalyst is in the form of particles having an average diameter dcat satisfying the following relation: dcat>2×dSWCNT or in the form of a continuous film.
摘要翻译：本发明涉及一种具有直径d SWCNT的单壁碳纳米管（SWCNT）的制备方法，其包括（i）提供包含单壁碳纳米管的段S SWCNT的前体元素，制备的片段S SWCNT 由至少一个由邻苯乙烯环形成的环，并且具有开口的第一末端E1和与第一末端E1相对的第二末端E2，（ii）通过与碳气相反应生长前体元素在含金属的催化剂的表面上的源化合物，其中前体元素经由段SWCNT的开口端E1与含金属的催化剂的表面接触，并且含金属的催化剂为具有满足以下关系的平均直径d cat的颗粒：d cat> 2×d SWCNT或连续膜的形式。

5. 发明申请

US20160096734A2 Method of Producing a Freestanding Thin Film of Nano-Crystalline Carbon 有权
标题翻译：制备纳米晶碳独立薄膜的方法
公开(公告)号：US20160096734A2
公开(公告)日：2016-04-07
申请号：US14560919
申请日：2014-12-04
申请人： FEI Company , Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V
发明人： Bart Buijsse , Radostin Stoyanov Danev , Kasim Sader
IPC分类号： C01B31/04 , H01J37/31 , H01J37/22
CPC分类号： C01B32/20 , H01J37/20 , H01J37/22 , H01J37/26 , H01J37/31 , H01J2237/3114
摘要： A freestanding thin film of nano-crystalline graphite is described, as well as a method of producing a freestanding thin film of nano-crystalline graphite including: providing a freestanding thin film of amorphous carbon, heating the freestanding thin film to a high temperature in an inert atmosphere or in a vacuum; and allowing the freestanding thin film to cool down, as a result of which a freestanding thin film of nano-crystalline graphite is formed. The films can be used, for example, as phase plates in a Transmission Electron Microscope.
摘要翻译：描述了独立的纳米晶体石墨薄膜，以及制造纳米晶体石墨的独立薄膜的方法，包括：提供独立的无定形碳薄膜，将独立的薄膜加热到高温下惰性气氛或真空中; 并且允许独立的薄膜冷却，由此形成独立的纳米晶体石墨薄膜。这些膜可以用作例如透射电子显微镜中的相位板。

6. 发明申请

US20150153477A1 DISASTER ALERT MEDIATION USING NATURE 审中-公开
标题翻译：使用自然的灾难警报调解
公开(公告)号：US20150153477A1
公开(公告)日：2015-06-04
申请号：US14397876
申请日：2013-05-08
申请人： MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V.
发明人： Martin Wikelski , Uschi Muller , Wolfgang Arne Heidrich , Franz Xaver Kummeth
IPC分类号： G01W1/10 , A61B5/16 , A61B5/0476 , A61B5/00 , G06Q50/26 , A61B5/0205
CPC分类号： G01W1/10 , A61B5/02055 , A61B5/0476 , A61B5/16 , A61B5/42 , G01V1/008 , G06Q50/265
摘要： A method for forecasting an environmental event/a type of environmental event includes acquiring at least one test data set of at least one behavioural and/or physiological parameter of a population of animals; generating a test profile based on said at least one test data set, representing behaviour and/or physiological status of the population of animals; calculating a ratio between the test profile and a first reference profile; and setting an alert, if said ratio reaches a predefined threshold value. A system for forecasting an environmental event/a type of environmental event employs at least one data acquisition unit configured to acquire at least one data set of at least one behavioural and/or physiological parameter of a population of animals; at least one profile generation unit configured to generate at least one first reference profile and/or at least one test profile wherein each profile is based on at least one data set; at least one ratio calculation unit configured to calculate at least one ratio between the at least one test profile and one of the at least one first reference profile; at least one alert unit configured to raise an alert if at least one of the at least one calculated ratio reaches a predefined threshold value.
摘要翻译：一种预测环境事件/一种环境事件的方法包括获取动物群体的至少一个行为和/或生理参数的至少一个测试数据集; 基于所述至少一个测试数据集生成表示动物群体的行为和/或生理状态的测试概况; 计算测试轮廓和第一参考轮廓之间的比率; 并且如果所述比率达到预定义的阈值，则设置警报。用于预测环境事件/一种环境事件的系统使用至少一个数据获取单元，其被配置为获取至少一个动物群体的行为和/或生理参数的数据集; 至少一个简档生成单元被配置为生成至少一个第一参考简档和/或至少一个测试简档，其中每个简档基于至少一个数据集; 至少一个比率计算单元，被配置为计算所述至少一个测试轮廓与所述至少一个第一参考轮廓中的一个之间的至少一个比率; 至少一个警报单元，被配置为如果所述至少一个所计算的比率中的至少一个达到预定义的阈值，则提醒警报。

7. 发明授权

US09002857B2 Methods for searching with semantic similarity scores in one or more ontologies 有权
标题翻译：在一个或多个本体中用语义相似度分数进行搜索的方法
公开(公告)号：US09002857B2
公开(公告)日：2015-04-07
申请号：US12461517
申请日：2009-08-13
申请人： Peter N. Robinson , Marcel H. Schulz , Sebastian Bauer , Sebastian Köhler
发明人： Peter N. Robinson , Marcel H. Schulz , Sebastian Bauer , Sebastian Köhler
IPC分类号： G06F17/30
CPC分类号： G06F17/3053 , G06F17/30722
摘要： A method assigns importance ranks to documents within repositories or databases, such as any database of documents such as books or other printed material, electronic documentation, and pages within the world-wide web. The method uses a corpus of indexed documents that has been annotated to the terms of one or more ontologies in order to assign a semantic similarity score to queries based on terms taken from the ontologies. A statistical model is used to test the significance of matches between query terms and documents or categories. The method results in an acceleration of over 10,000-fold for realistic queries and ontologies, and makes it practicable to calculate P-values dynamically or to keep database annotations and the related P-value distributions up to date by frequent recalculation.
摘要翻译：一种方法将重要级别分配到存储库或数据库中的文档，例如任何数据库的文档，如书籍或其他打印材料，电子文档和世界各地的网页中的页面。该方法使用已经注释到一个或多个本体的术语的索引文档的语料库，以便基于从本体获取的术语来向查询分配语义相似性分数。统计模型用于测试查询项和文档或类别之间匹配的重要性。该方法对于现实的查询和本体，导致加速超过10,000倍，并且通过频繁重新计算，动态地计算P值或通过频繁重新计算来保持数据库注释和相关的P值分布是最新的。

8. 发明授权

US08989267B2 High dynamic range codecs 有权
公开(公告)号：US08989267B2
公开(公告)日：2015-03-24
申请号：US14076000
申请日：2013-11-08
申请人： Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V.
发明人： Alexander Efremov , Rafal Mantiuk , Grzegorz Krawczyk , Karol Myszkowski , Hans-Peter Seidel
IPC分类号： H04N1/417 , H04N19/105 , H04N19/50 , H04N19/63 , H04N19/186 , H04N19/184 , H04N19/187 , H04N19/33 , H04N19/98 , H04N19/59
CPC分类号： H04N19/50 , H04N19/105 , H04N19/124 , H04N19/136 , H04N19/184 , H04N19/186 , H04N19/187 , H04N19/33 , H04N19/59 , H04N19/63 , H04N19/98
摘要： A method for encoding high dynamic range (HDR) images involves providing a lower dynamic range (LDR) image, generating a prediction function for estimating the values for pixels in the HDR image based on the values of corresponding pixels in the LDR image, and obtaining a residual frame based on differences between the pixel values of the HDR image and estimated pixel values. The LDR image, prediction function and residual frame can all be encoded in data from which either the LDR image of HDR image can be recreated.

9. 发明授权

US08957029B2 Peptide for determining actin structures in living cells 有权
标题翻译：用于测定活细胞中肌动蛋白结构的肽
公开(公告)号：US08957029B2
公开(公告)日：2015-02-17
申请号：US12744822
申请日：2008-11-27
申请人： Roland Wedlich-Söldner , Michael Sixt , Julia Riedl , Alvaro Crevenna
发明人： Roland Wedlich-Söldner , Michael Sixt , Julia Riedl , Alvaro Crevenna
IPC分类号： A61K38/16 , C07K14/00 , C07K1/13 , A61K39/12 , G01N33/533 , G01N33/569 , C07K14/395 , G01N33/50
CPC分类号： C07K14/395 , C07K14/43595 , C07K2319/60 , G01N33/502 , G01N33/5026 , G01N33/56966
摘要： The present invention relates to novel peptides capable of binding to action. The peptides are useful in methods for detecting actin in vitro or in living cells.
摘要翻译：本发明涉及能够结合作用的新肽。肽可用于体外或活细胞中肌动蛋白的检测。

10. 发明授权

US08846854B2 Sulfonated poly(arylenes), polymer compounds and methods of producing the same 有权
标题翻译：磺化聚（亚芳基），聚合物化合物及其制备方法
公开(公告)号：US08846854B2
公开(公告)日：2014-09-30
申请号：US13679415
申请日：2012-11-16
申请人： Max-Planck-Gesellschaft zur Forderung der Wissenschaften e V.
发明人： Michael Schuster , Klaus-Dieter Kreuer , Henrik Thalbitzer Andersen , Joachim Maier
IPC分类号： C08G75/00 , C08L81/06 , C08J5/22 , C08G75/20
CPC分类号： C08G75/20 , C08J5/2256 , C08J2381/06 , C08L81/06 , C08L2666/02
摘要： A copolymer containing, in addition to recurring elements of a sulfonated poly(arylene) containing exclusively recurring structural element(s) of the general formulas —[—Ar1(SO3M)n-X—]— and —[—Ar2(SO3M)n-Y—]—, wherein X and Y, which are identical or different from each other, each represent an electron-acceptor group, Ar1 and Ar2, which are either identical or different from each other, represent an aromatic or heteroaromatic ring system with 5-18 ring atoms; wherein the aromatic or heteroaromatic ring system, in addition to the SO3M and the substituents X and Y, optionally comprises additional substituents which are not electron-donor groups; M represents monovalent cation and n is an integral number between 1 and 4; and wherein X, Y, Ar1, Ar2, M and n can be identical or different in various structural elements, independently of each other, one or several additional elements of at least one additional monomer or macromonomer.
摘要翻译：除了含有通式 - [-Ar1（SO3M）nX - ] - 和 - [ - Ar2（SO3M）nY-]的重复结构元件的磺化聚（亚芳基）的重复元素外， - ，其中彼此相同或不同的X和Y各自表示彼此相同或不同的电子受体基团Ar1和Ar2表示具有5-18个环的芳族或杂芳族环系原子其中除了SO 3 M和取代基X和Y之外，芳族或杂芳族环系统任选地包含不是电子给体基团的另外的取代基; M表示一价阳离子，n为1至4之间的整数; 并且其中X，Y，Ar 1，Ar 2，M和n可以在各种结构元件中相同或不同，彼此独立地是至少一种另外的单体或大分子单体的一种或多种另外的元素。

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