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    • 1. 发明申请
    • MEDICAL TREATMENT MONITORING SYSTEM AND METHOD
    • 医疗治疗监测系统及方法
    • US20110112860A1
    • 2011-05-12
    • US13008476
    • 2011-01-18
    • Bruce A. KEHR
    • Bruce A. KEHR
    • G06Q50/00G06Q10/00
    • G06Q50/22G06F19/325G06F19/3456G16H10/60G16H15/00G16H50/70Y02A90/22Y02A90/26
    • A method and system is provided for monitoring the treatment of one or more patients with one or more medications. A medical treatment plan is defined as a set of data elements stored in a database and representative of a patient configuration file. The data elements are translated into a sequence of prompt and record events, which are communicated to one or more remote monitoring devices. Patient response data, supplied by the patients in response to the events and relating at least in part to a record of the intake of the medication by the patient, are obtained, recorded, and uploaded into the database. The patient response data are correlated with additional data relating to patient health or economic outcomes, for example using statistical analysis and data mining. The correlation can be used to adjust dosing recommendations to improve clinical outcome, reduce side-effects, and eliminate drug interactions.
    • 提供了一种用于监测一种或多种患有一种或多种药物的患者的治疗的方法和系统。 治疗方案被定义为存储在数据库中并代表患者配置文件的一组数据元素。 将数据元素转换成一系列提示和记录事件,这些事件被传送到一个或多个远程监视设备。 由患者响应于事件提供并且至少部分地关联患者的药物摄入记录的患者反应数据被获得,记录并上传到数据库中。 患者反应数据与与患者健康或经济结果相关的附加数据相关,例如使用统计分析和数据挖掘。 相关性可用于调整剂量建议,以改善临床结果,减少副作用,并消除药物相互作用。
    • 3. 发明申请
    • Clinical trial monitoring system and method
    • 临床试验监测系统及方法
    • US20050149869A1
    • 2005-07-07
    • US10887741
    • 2004-07-09
    • Bruce KehrRobert Benson
    • Bruce KehrRobert Benson
    • G06F3/00G06Q10/00G06Q30/00
    • G06Q30/02G06Q10/06
    • A method and system are presented for monitoring the performance of a clinical trial, and the adherence of trial participants to a protocol for the clinical trial. A plurality of templates are provided, which can be populated with protocol data can be entered that relate to behavioral elements of the protocol. The populated templates are downloaded to a plurality of remote devices. The remote devices generate, upon receipt of the templates populated with protocol data, prompting messages that prompt participants whether protocol elements have been performed, and that request performance data relating to any actual performance of the protocol elements. Based on the performance data, reports are periodically generated that compare actual performance of the protocol elements with expected or desired performance of the protocol elements.
    • 提出了一种方法和系统,用于监测临床试验的性能,以及试验参与者对临床试验方案的依从性。 提供了多个模板,其可以填充与协议的行为元素相关的协议数据。 填充的模板被下载到多个远程设备。 远程设备在接收到用协议数据填充的模板时生成提示消息,提示参与者是否已经执行协议元素,并且请求涉及协议元件的任何实际性能的性能数据。 根据性能数据,定期生成报告,将协议元素的实际性能与协议元素的期望或期望性能进行比较。
    • 5. 发明授权
    • Method of and apparatus for monitoring the management of disease
    • 监测疾病管理的方法和手段
    • US5642731A
    • 1997-07-01
    • US352828
    • 1994-12-02
    • Bruce A. Kehr
    • Bruce A. Kehr
    • A61J7/04G06F19/00G07F11/62G04B47/00A61B5/00G06F17/00
    • G07F17/0092A61J7/0084A61J7/0418A61J7/0436A61J7/0454A61J7/0481G06F19/3462G07F11/62A61J2200/30A61J2205/70A61J7/0445
    • The present invention monitors the disease process and health of a patient undergoing drug treatment. A microprocessor-based medication dispenser provides for recording a variety of clinical information data; such as illness symptoms, side effects, general health ratings, adverse drug interactions, illness attitudes, and lifestyle habits at various times during a drug delivery cycle. The date and time of entry of the specific clinical information is entered, and correlated with the date and time when the patient has taken or missed a particular medication. The effects of the presumptive blood levels of one or more medications can then be assessed, as to their impact on the disease process, and any additional effects on the body. The device can analyze the data and display a response to it, or download the data into another device. The second device can analyze the data, and upload new information into the first device, to tell the patient to alter his or her behavior in taking medication. In this fashion, better disease management will occur.
    • 本发明监测经历药物治疗的患者的疾病过程和健康。 基于微处理器的药物分配器提供记录各种临床信息数据; 例如疾病症状,副作用,一般健康评级,不良药物相互作用,疾病态度和生活习惯在药物递送期间的不同时间。 输入特定临床信息的日期和时间,并且与患者服用或错过特定药物的日期和时间相关联。 然后可以评估一种或多种药物的推测血液水平的影响,其对疾病过程的影响以及对身体的任何其他影响。 该设备可以分析数据并显示对其的响应,或将数据下载到另一个设备中。 第二个设备可以分析数据,并将新信息上传到第一个设备,告诉患者改变服用药物的行为。 以这种方式,会发生更好的疾病管理。
    • 6. 发明授权
    • Method, apparatus and operating system for managing the administration
of medication and medical treatment regimens
    • 用于管理药物治疗和治疗方案的方法,装置和操作系统
    • US6085752A
    • 2000-07-11
    • US398816
    • 1999-09-20
    • Bruce A. KehrEvan SohnJames E. StarnesDavid MaurerIrwin D. BaumelDavid S. Stempler
    • Bruce A. KehrEvan SohnJames E. StarnesDavid MaurerIrwin D. BaumelDavid S. Stempler
    • A61B5/00A61J7/04A61B19/00
    • A61B5/4839A61B5/0002A61J7/0481G06F19/3462A61J2200/30A61J2205/20A61J2205/30A61J2205/50A61J2205/70A61J7/0418Y10S128/92
    • A medical monitoring device, operating system, and method is provided for managing administration of medical treatment regimens for treating a patient's medical conditions. The device stores medication schedule data, treatment data, patient query data, and patient response data. The device includes a controller for controlling modes of operation of the device, controlling access of the memory, controlling display of the treatment data and the patient query data on a display, receiving and processing patient response data, tracking timing, and providing scheduled medication alarm signals. The device further includes dedicated keys interfaced with the controller. Each dedicated key is associated with one of the medical treatment regimens, and initiates the display of treatment messages relating to the associated medical treatment regimen. Successive actuation of each dedicated key initiates the display of further treatment messages relating to the associated medical treatment regimen. The device further includes soft function keys interfaced with the controller. The soft function keys signal the controller, commanding it to execute different modes of operation of the medical monitoring device. The device provides scheduled medication alarm signals that alert the user concerning prescribed medications due to be taken.
    • 提供医疗监视装置,操作系统和方法,用于管理用于治疗患者的医疗状况的医疗方案的管理。 该设备存储药物调度数据,治疗数据,患者查询数据和患者响应数据。 该装置包括控制器,用于控制设备的操作模式,控制存储器的访问,控制显示器上的治疗数据和患者查询数据的显示,接收和处理患者的响应数据,跟踪定时,并提供计划的药物报警 信号。 该设备还包括与控制器接口的专用键。 每个专用密钥与其中一种治疗方案相关联,并启动显示与相关医疗方案相关的治疗消息。 每个专用钥匙的连续致动启动显示与相关医疗方案相关的进一步治疗消息。 该设备还包括与控制器接口的软功能键。 软键功能键使控制器发出信号,指示控制器执行医疗监控设备的不同操作模式。 该装置提供预定的药物报警信号,其提醒用户关于由于被摄取的规定的药物。
    • 8. 发明授权
    • Electronic medication monitoring and dispensing method
    • 电子药物监测和分配方法
    • US5752235A
    • 1998-05-12
    • US556626
    • 1990-07-23
    • Bruce A. KehrDavid LernerRichard D. DemenusMichael J. Edl
    • Bruce A. KehrDavid LernerRichard D. DemenusMichael J. Edl
    • A61J7/04G06F19/00G07F11/62G08B21/24G06F15/02
    • A61J7/0481A61J7/0084A61J7/0418A61J7/0436A61J7/0454G06F19/3462G07F11/62G07F17/0092G08B21/24A61J2200/30A61J2205/70A61J7/0409A61J7/0445
    • A device for monitoring medication of a patient and for prompting the patient into certain medication taking schedule and/or certain programming steps and routines. The device has a plurality of compartments, each of which may store medication, and an electrical signaling system to emit medication alert signals from time-to-time, each of which said signals indicates (a) that medication should be taken, (b) from which compartment the medication should be taken, (c) and the quantity of medication to be taken. If a designated compartment is not opened and closed within a predetermined period of time, the electrical signaling system will display an alarm and the event will be recorded as a missed medication event, unless the patient then opens the designated compartment. If each designated compartment is opened and closed, the take-medication signal and the alarm (if operating) are turned off and the event is recorded for later review. The device may be constructed in one piece with hinged doors for each pill compartment, or each pill compartment may be a separate "drawer" sliding into a main unit.
    • 一种用于监测患者的药物并用于促使患者进入某些药物的装置,其采取计划和/或某些编程步骤和例程。 该装置具有多个隔间,每个隔间可以存储药物,以及一个电信号系统,用于不时地发出药物警报信号,每个隔间都表示(a)应该服用药物,(b) 应从哪个隔间取药物,(c)和服用药物的数量。 如果在预定时间段内没有打开和关闭指定的隔间,则电信号系统将显示警报,并且事件将被记录为错过的药物事件,除非患者然后打开指定的隔间。 如果每个指定的隔间被打开和关闭,则取消药物信号和警报(如果操作)被关闭,事件被记录以备以后审查。 该装置可以用于每个药丸隔室的铰接门构成一体,或者每个药丸隔室可以是滑入主单元的单独的“抽屉”。