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1. 发明授权

US08871249B2 Medicated patch 有权
标题翻译：补药
公开(公告)号：US08871249B2
公开(公告)日：2014-10-28
申请号：US12919715
申请日：2009-02-09
申请人： Naoki Yamamoto , Kumi Morimoto , Akio Takeuchi , Kenji Ishigaki
发明人： Naoki Yamamoto , Kumi Morimoto , Akio Takeuchi , Kenji Ishigaki
IPC分类号： A61F13/00 , A61K31/4985 , A61K9/70
CPC分类号： A61K31/4985 , A61K9/7061
摘要： Provided is a medicated patch containing a medicinal agent, an adhesive base material and a tackifier, where the medicinal agent is varenicline or a pharmaceutically acceptable salt thereof, the adhesive base material is a rubbery adhesive base material and the tackifier is a rosin-based tackifier selected from the group consisting of rosin, rosin derivatives and hydrogenated products of the foregoing, or a non-rosin-based tackifier selected from the group consisting of aliphatic hydrocarbon resins and alicyclic hydrocarbon resins, and when a non-rosin-based tackifier is added as the tackifier, a solubilizer for the medicinal agent is further added, the solubilizer containing an alcohol-based solubilizer having at least a solubility parameter of 20-35.
摘要翻译：本发明提供一种含有药剂，粘合剂基材和增粘剂的药膏，其中药剂为伐仑克林或其药学上可接受的盐，粘合剂基材为橡胶性粘合剂基材，增粘剂为松香类增粘剂选自上述的松香，松香衍生物和氢化产物，或选自脂肪族烃树脂和脂环族烃树脂的非松香类增粘剂，并且当添加非松香类增粘剂时作为增粘剂，还添加了用于药剂的增溶剂，该增溶剂含有至少具有20-35的溶解度参数的醇基增溶剂。

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