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1. 发明申请

US20210047612A1 INJECTABLE OFF-THE- SHELF CARTILAGE, TENDON, AND LIGAMENT REPAIR COMPOSITIONS AND METHODS OF USE 有权
公开(公告)号：US20210047612A1
公开(公告)日：2021-02-18
申请号：US16978407
申请日：2019-03-06
申请人： Sarindr BHUMRATANA , Terri-Ann KELLY , Eric Meade JEFFRIES , Olivia Spencer BEANE , Angela Hai HUANG , EpiBone, Inc.
发明人： Sarindr BHUMRATANA , Terri-Ann KELLY , Eric Meade JEFFRIES , Olivia Spencer BEANE , Angela Hai HUANG
IPC分类号： C12N5/00 , C12N5/077 , A61K9/06 , A61K9/50 , A61K38/18 , A61K9/00 , A61K31/726 , A61K38/39 , A61L27/52 , A61L27/54 , A61L27/38 , A61L27/36 , A61L27/24 , A61L27/20 , A61L27/18
摘要： Compositions comprising a condensed mesenchymal cell body and a hydrogel are provided. The compositions may further include drugs or growth factors. The condensed mesenchymal cell body may include a connective tissue cell, or even a progenitor cell capable of producing connective tissue extracellular matrices such collagen and glycosaminoglycan. Also provided are methods of treating connective tissue defects, cartilage injury, and cartilage degradation.

2. 发明授权

US09880272B2 Calculation of detecting depth and moving speed of objects with coded pulses based on speed changes of ultrasound/sound 有权
公开(公告)号：US09880272B2
公开(公告)日：2018-01-30
申请号：US14645475
申请日：2015-03-12
申请人： Hai Huang , Tony Huang
发明人： Hai Huang , Tony Huang
IPC分类号： G01S15/58 , G01S7/523 , G01S15/89 , G01S15/02
CPC分类号： G01S7/523 , G01S15/02 , G01S15/58 , G01S15/8986
摘要： During transmission, a speed of ultrasound pulses gradually reduces due to their energy loss from acoustic impedance. A thickness and a density of piezoelectric (PZT) elements and a sound speed in the PZT elements decides energy of the ultrasound pulses and their detecting depth. A speed of moving objects and an angle of the moving objects with the ultrasound pulses may change a speed of reflected ultrasound pulses and affect their time of flight (TOF) and TOF shift. A method of Coding ultrasound pulses combines advantages of a continuous wave ultrasound and a pulsed wave ultrasound. So, it can be used to obtained the TOF and the TOF shift and calculate the depth and the moving speed of the detecting objects, which also avoids a problem of an aliasing for highly moving speed of the objects.

3. 发明申请

US20210356573A1 TWO DIMENSION AND THREE DIMENSION IMAGING BASED ON SPEED CHANGES OF SOUND/ULTRASOUND 有权
公开(公告)号：US20210356573A1
公开(公告)日：2021-11-18
申请号：US17388175
申请日：2021-07-29
申请人： Hai Huang , Tony Huang
发明人： Hai Huang , Tony Huang
IPC分类号： G01S7/523 , G01S15/89 , G01S15/02 , G01S15/58
摘要： The invention is based on speed changes of sound/ultrasound pulses and a fixed detecting depth between a transducer and sampling points to collect information of the detecting depth and/or a velocity of motionless and/or moving objects from the sampling points to construct two-dimension or three-dimension images of the sampling points. By taking advantages of a pulse ultrasound and a continuous ultrasound, a method of coded sound pulses can simultaneously collect the information of the detecting depth and the velocity from the sampling points, which improves imaging quality. Calculating a speed of the moving objects by simultaneously detecting time-of-flight (TOF) and TOF shift at same site from two separated piezoelectric (PZT) elements improves testing results with accuracy, simplification and reproducibility. An aliasing can be rectified based on the TOF and the TOF shift.

4. 发明申请

US20200156409A1 ADJUSTABLE AIRLESS TIRE SYSTEM WITH SPRING-LOADED SHOCK ABSORBERS 审中-公开
公开(公告)号：US20200156409A1
公开(公告)日：2020-05-21
申请号：US16752658
申请日：2020-01-26
申请人： Hai Huang , Tony Huang
发明人： Hai Huang , Tony Huang
IPC分类号： B60C7/14 , B60B9/02
摘要： An adjustable airless tire system includes spring-loaded shock absorbers to provide suspension to absorb impact energy and damp spring oscillations; and a metallic hawser loop to transfer the impact energy from the spring-loaded shock absorbers of the ground contact surface of the tire to whole spring-loaded shock absorbers within the tire to maximize their suspension potential. A control component adjusts a tension and a size of the ground contact surface of the tire according to the road conditions, which improve its oil efficiency, comfortability, controllability and safety. An enhanced rim of a wheel keeps an appropriate distance from the tire to protect the spring-loaded shock absorbers and provide limited moving ability for the vehicle if the airless system loses their functions. A curved tire forms a closed space between the tire and the rim to prevent foreign objects from sticking between them.

5. 发明申请

US20200094616A1 ADJUSTABLE AIRLESS TIRE WITH A PISTON SYSTEM 审中-公开
公开(公告)号：US20200094616A1
公开(公告)日：2020-03-26
申请号：US16183681
申请日：2018-11-07
申请人： Hai Huang , Tony Huang
发明人： Hai Huang , Tony Huang
IPC分类号： B60B9/24 , B60B9/20
摘要： An adjustable airless tire with a piston system includes a fluid container connecting with a plurality of spoke structure of pistons to transfer a load of a vehicle from a ground contact surface of a tire to whole walls of the tire. A sensor detects a tension of the tire and a variation of the tension during driving. A control component adjusts the tension of the tire according the load of the vehicle and the road conditions to improve its fuel efficiency, comfortability, controllability and safety. A rim of a wheel keeps an appropriate distance from the tire to limit the maximal level of downward movement of the supporting rods, and support the load of the vehicle if the tire is overload or the piston system lose their function. A transversely curved tire forms closed space between the tire and the rim of the wheel to prevent sticking of foreign objects between them.

6. 发明申请

US20150362590A1 CALCULATING VELOCITY OF MOVING OBJECTS WITH TIME OF FLIGHT OF ULTRASOUND PULSES AND RECTIFYING DETECTING DEPTH WITH REDUCED ULTRASOUND SPEED 审中-公开
标题翻译：用超声波脉冲的时间计算移动物体的速度，并用减少的超声波速度进行修复检测深度
公开(公告)号：US20150362590A1
公开(公告)日：2015-12-17
申请号：US14305074
申请日：2014-06-16
申请人： Hai Huang
发明人： Hai Huang
IPC分类号： G01S7/52 , A61B8/08 , A61B8/06
CPC分类号： G01S7/52017 , A61B8/06 , A61B8/488 , A61B8/5223 , A61B8/5269 , G01S15/006
摘要： During transmission the speed of ultrasound pulses gradually reduces due to their energy loss. So, calculating the detecting depth with fixed transmitting speed may distort two dimensional images due to the reduction of pulse speed. Correcting TOF error will rectify the depth registration and improve the quality of images.The thickness of activated piezoelectric materials decides the size and quantity of ultrasound pulses, which is related to its penetrating ability. So, increasing thickness of activated piezoelectric materials will increase the quantity of ultrasound pulses, which increase their penetrating depth.Moving objects change the speed of reflected ultrasound pulses. The forward moving objects increase reflected speed and reversely moving objects decrease reflected speed, which change their TOF. Therefore TOF shift can be used to calculate the velocity of moving objects in the continuous and pulse wave and color ultrasound, and correct aliasing of pulse and color ultrasound.
摘要翻译：在传输期间，超声脉冲的速度由于其能量损失而逐渐降低。因此，以固定的传输速度计算检测深度可能会由于脉冲速度的降低而扭曲二维图像。更正TOF错误将纠正深度注册，提高图像质量。激活的压电材料的厚度决定了超声脉冲的尺寸和数量，这与其穿透能力有关。因此，增加活化压电材料的厚度将增加超声脉冲的数量，从而增加其穿透深度。移动的物体改变反射超声脉冲的速度。向前移动的物体增加反射速度，反向移动物体降低反射速度，从而改变其TOF。因此，可以使用TOF移位来计算连续脉冲波和彩色超声中移动物体的速度，并纠正脉冲和彩色超声波的混叠。

7. 发明申请

US20150185318A1 CALCULATION OF DETECTING DEPTH AND MOVING SPEED OF OBJECTS WITH CODED PULSES BASED ON SPEED CHANGES OF ULTRASOUND/SOUND 审中-公开
标题翻译：基于超声波/声速变化的编码脉冲检测深度和物体移动速度的计算
公开(公告)号：US20150185318A1
公开(公告)日：2015-07-02
申请号：US14645475
申请日：2015-03-12
申请人： Tony Huang , Hai Huang
发明人： Hai Huang , Tony Huang
IPC分类号： G01S15/58
CPC分类号： G01S7/523 , G01S15/02 , G01S15/58 , G01S15/8986
摘要： During transmission, a speed of ultrasound pulses gradually reduces due to their energy loss from acoustic impedance. A thickness and a density of piezoelectric (PZT) elements and a sound speed in the PZT elements decides energy of the ultrasound pulses and their detecting depth. A speed of moving objects and an angle of the moving objects with the ultrasound pulses may change a speed of reflected ultrasound pulses and affect their time of flight (TOF) and TOF shift. A method of Coding ultrasound pulses combines advantages of a continuous wave ultrasound and a pulsed wave ultrasound. So, it can be used to obtained the TOF and the TOF shift and calculate the depth and the moving speed of the detecting objects, which also avoids a problem of an aliasing for highly moving speed of the objects.
摘要翻译：在传输过程中，由于声波阻抗的能量损失，超声脉冲的速度逐渐降低。压电（PZT）元件的厚度和密度以及PZT元件的声速决定了超声脉冲的能量及其检测深度。移动物体的速度和移动物体与超声脉冲的角度可能会改变反射的超声脉冲的速度并影响其飞行时间（TOF）和TOF偏移。编码超声脉冲的方法结合了连续波超声和脉冲波超声的优点。因此，可以用于获得TOF和TOF移位并计算检测对象的深度和移动速度，这也避免了物体高度移动速度的混叠问题。

8. 发明授权

US10324174B2 Two dimension and three dimension imaging with coded pulses based on speed changes of sound/ultrasound 有权
公开(公告)号：US10324174B2
公开(公告)日：2019-06-18
申请号：US15613308
申请日：2017-06-05
申请人： Hai Huang , Tony Huang
发明人： Hai Huang , Tony Huang
IPC分类号： G01S7/52 , G01S7/523 , G01S15/89 , G01S15/02 , G01S15/58
摘要： During transmission, a speed of sound pulses gradually reduces due to acoustic impedance. Regulating a length or a density or a sound speed of the sound pulses affects their average speed in the transmitting medium, sound intensity and detecting depth. Time of flight (TOF) and TOF shift can be used to calculate the depth and moving speed of detecting objects. Calculating a speed of moving objects by simultaneously detecting TOF shift at same site from two separated piezoelectric (PZT) elements improves the testing results with accuracy, simplification and reproducibility. Coding sound pulses to obtained the TOF and the TOF shift will simultaneously calculate the depth and the moving speed of sampling points, which can be used to construct 2D and 3D images for these motionless and/or moving sampling points. Coded sound pulses also improves the quality of the imaging.

9. 发明授权

US11609317B2 Two dimension and three dimension imaging based on speed changes of sound/ultrasound 有权
公开(公告)号：US11609317B2
公开(公告)日：2023-03-21
申请号：US17388175
申请日：2021-07-29
申请人： Hai Huang , Tony Huang
发明人： Hai Huang , Tony Huang
IPC分类号： G01S7/523 , G01S15/89 , G01S15/02 , G01S15/58
摘要： The invention is based on speed changes of sound/ultrasound pulses and a fixed detecting depth between a transducer and sampling points to collect information of the detecting depth and/or a velocity of motionless and/or moving objects from the sampling points to construct two-dimension or three-dimension images of the sampling points. By taking advantages of a pulse ultrasound and a continuous ultrasound, a method of coded sound pulses can simultaneously collect the information of the detecting depth and the velocity from the sampling points, which improves imaging quality. Calculating a speed of the moving objects by simultaneously detecting time-of-flight (TOF) and TOF shift at same site from two separated piezoelectric (PZT) elements improves testing results with accuracy, simplification and reproducibility. An aliasing can be rectified based on the TOF and the TOF shift.

10. 发明申请

US20200094625A1 ADJUSTABLE AIRLESS TIRE WITH AN AIR SAC WITHIN A WHEEL 审中-公开
公开(公告)号：US20200094625A1
公开(公告)日：2020-03-26
申请号：US16416069
申请日：2019-05-17
申请人： Hai Huang , Tony Huang
发明人： Hai Huang , Tony Huang
IPC分类号： B60C7/12 , B60B9/18 , B60B1/06
摘要： An adjustable airless tire with an air sac within a wheel includes an air sac located within a wheel to transfer a load of a vehicle from a ground contacting area of a tire to whole walls of the tire through a plurality of spoke structure of rods that connect with the walls of the air sac and the tire. A sensor detects a tension of the tire and a variation of a tension during driving. A control component adjusts the tension of the tire according the load of the vehicle and road conditions to improve its fuel efficiency, comfortability, controllability and safety. A rim of the wheel keeps an appropriate distance from the tire to limit the maximal level of upward movement of the rods. A transversely curved tire mounted to the rim of the wheel to form closed space between the tire and the wheel.

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