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1. 发明授权

US5405363A Implantable cardioverter defibrillator having a smaller displacement volume 失效
标题翻译：具有较小排量的植入式心律转复除颤器
公开(公告)号：US5405363A
公开(公告)日：1995-04-11
申请号：US263257
申请日：1994-06-21
申请人： Mark W. Kroll , Theodore P. Adams , Kenneth M. Anderson , Charles U. Smith
发明人： Mark W. Kroll , Theodore P. Adams , Kenneth M. Anderson , Charles U. Smith
IPC分类号： A61N1/375 , A61N1/378 , A61N1/39 , H01M2/10 , H01M6/50 , H01M16/00
CPC分类号： A61N1/375 , A61N1/3787 , A61N1/3931 , A61N1/3956 , A61N1/3975 , H01M16/00 , A61N1/3758 , A61N1/3906 , A61N1/3912 , H01M2/1066 , H01M6/5016
摘要： A capacitor-discharge implantable cardioverter defibrillator (ICD) has a relatively smaller displacement volume of less than about 90 cc. The smaller volume of the ICD is achieved by selecting and arranging the internal components of the ICD to deliver a maximum defibrillation countershock optimized in terms of a minimum physiologically effective current (I.sub.pe), rather than a minimum defibrillation threshold energy (DFT). As a result of the optimization in terms of a minimum effective current I.sub.pe, there is a significant decrease in the maximum electrical charge energy (E.sub.c) that must be stored by the capacitor of the ICD to less than about 30 Joules, even though a higher safety margin is provided for by the device. Due to this decrease in the maximum E.sub.c, as well as corollary decreases in the effective capacitance value required for the capacitor and the net energy storage required of the battery, the overall displacement volume of the ICD is reduced to the point where subcutaneous implantation of the device in the pectoral region of human patients is practical. The size of the capacitor is reduced because the effective capacitance required can be less than about 125 .mu. F. By optimizing both the charging time and the countershock duration for the smaller maximum E.sub.c, the size of the battery is reduced because the total energy storage capacity can be less than about 1.0 Amp-hours. In the preferred embodiment, the charging time for each defibrillation countershock is reduced to less than about 10 seconds and the pulse duration of the countershock is reduced to less than about 6 milliseconds.
摘要翻译：电容放电可植入式心律转复除颤器（ICD）具有小于约90cc的相对较小的置换体积。通过选择和布置ICD的内部部件来实现ICD的体积较小，以提供根据最小生理有效电流（Ipe）而不是最小除颤阈值能量（DFT）优化的最大除颤反相。作为最小有效电流Ipe优化的结果，ICD的电容器必须存储的最大电荷能量（Ec）显着降低到小于约30焦耳，即使较高的设备提供安全余量。由于最大Ec的这种减小以及电容器所需的有效电容值和电池所需的净能量存储的必然减小，ICD的总位移体积减少到皮下植入在人类胸腔的器官是实用的。电容器的尺寸减小，因为所需的有效电容可以小于约125μF。通过优化较小的最大Ec的充电时间和反冲时间，电池的尺寸减小，因为总能量存储容量可以小于约1.0安培小时。在优选实施例中，每个去纤维颤动反射的充电时间减少到小于约10秒，并且该反冲的脉冲持续时间减小到小于约6毫秒。

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