专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20060293860A1 SYSTEM, METHOD, AND COMPUTER PRODUCT FOR CORRECTION OF FEATURE OVERLAP 审中-公开
标题翻译：系统，方法和计算机产品用于校正特征重叠
公开(公告)号：US20060293860A1
公开(公告)日：2006-12-28
申请号：US11427103
申请日：2006-06-28
申请人： Vincent Bressler , Albert Bukys , David Stern
发明人： Vincent Bressler , Albert Bukys , David Stern
IPC分类号： G06F19/00
CPC分类号： G16B25/00
摘要： In one embodiment, a method for correcting feature overlap in biological probe array data is described that comprises (a) receiving a first set of data comprising an intensity value for each of a plurality of features associated with a probe array; (b) calculating a crosstalk parameter for the first set of data using the intensity values of one or more test features and a plurality of features that neighbor each test feature; and (c) applying the crosstalk parameter to each intensity value in the first set of data to produce a second set of data.
摘要翻译：在一个实施例中，描述了用于校正生物探针阵列数据中的特征重叠的方法，其包括（a）接收第一组数据，其包括与探针阵列相关联的多个特征中的每一个的强度值; （b）使用一个或多个测试特征和邻近每个测试特征的多个特征的强度值来计算第一组数据的串扰参数; 以及（c）将所述串扰参数应用于所述第一组数据中的每个强度值以产生第二组数据。

2. 发明申请

US20040201844A1 System, method and product for providing a stable calibration standard for optical systems 审中-公开
标题翻译：用于为光学系统提供稳定校准标准的系统，方法和产品
公开(公告)号：US20040201844A1
公开(公告)日：2004-10-14
申请号：US10770717
申请日：2004-02-03
申请人： Affymetrix, INC., a Corporation Organized under the Laws of Delaware
发明人： Gregory C. Loney
IPC分类号： G01N021/64
CPC分类号： G01N21/6452 , G01N21/6428 , G01N2021/6419 , G01N2021/6421 , G01N2021/6441
摘要： A system is described for providing a wavelength of light that comprises: a scanner that provides a first wavelength; and an optical assembly that emits a second wavelength based, at least in part upon the first wavelength, wherein the second wavelength is not the result of a fluorescent emission.
摘要翻译：描述了一种用于提供波长的光的系统，其包括：提供第一波长的扫描仪; 以及至少部分地基于第一波长发射第二波长的光学组件，其中第二波长不是荧光发射的结果。

3. 发明申请

US20040030504A1 System, method, and computer program product for the representation of biological sequence data 审中-公开
标题翻译：用于表示生物序列数据的系统，方法和计算机程序产品
公开(公告)号：US20040030504A1
公开(公告)日：2004-02-12
申请号：US10423530
申请日：2003-04-25
申请人： Affymetrix, Inc. a Corporation Organized under the laws of Delaware
发明人： Gregg A. Helt , Cyrus L. Harmon
IPC分类号： G06F019/00 , G01N033/48 , G01N033/50
CPC分类号： G16B30/00 , G16B45/00
摘要： A method is described that includes the acts of receiving related biological sequences; and representing each of the related biological sequences as objects of a data model, where at least one of the objects is enabled to map at least one of the related biological sequences with at least one other of the related biological sequences.
摘要翻译：描述了包括接收相关生物序列的行为的方法; 并且将每个相关生物序列表示为数据模型的对象，其中至少一个对象能够将相关生物序列中的至少一个与至少一个相关生物序列进行映射。

4. 发明申请

US20020164709A1 Nucleic acid endocing growth factor protein 审中-公开
标题翻译：核酸内切生长因子蛋白
公开(公告)号：US20020164709A1
公开(公告)日：2002-11-07
申请号：US10083853
申请日：2002-02-26
申请人： Affymetrix, INC. A corporation organized under the laws of Delaware
发明人： Ron T. Shigeta JR. , Michael A. Siani-Rose
IPC分类号： C07K014/475 , C07H021/04 , C12P021/02 , C12N005/06
CPC分类号： C07K14/475 , A01K2217/05
摘要： The present invention provides a novel growth factor polynucleotide, growth factor polypeptide, gene delivery vehicles comprising and/or expressing the growth factor polynucleotide, antibodies and fragments capable of specifically binding to the growth factor polypeptide, receptors of the growth factor polypeptide, modulators of the growth factor activity, and modulators of growth factor expression. Also provided by the invention are host cells and transgenic organisms comprising the gene delivery vehicle of the present invention. Also provided by the invention are computer readable media containing the polynucleotide or polypeptide sequences of the present invention. Further provided are methods of using these compositions for diagnosis and treatment of growth factor associated diseases.
摘要翻译：本发明提供了一种新的生长因子多核苷酸，生长因子多肽，包含和/或表达生长因子多核苷酸的基因递送载体，能够特异性结合生长因子多肽的抗体和片段，生长因子多肽的受体，生长因子活性和生长因子表达的调节剂。本发明还提供了宿主细胞和包含本发明的基因递送载体的转基因生物。本发明还提供了包含本发明的多核苷酸或多肽序列的计算机可读介质。还提供了使用这些组合物来诊断和治疗生长因子相关疾病的方法。

5. 发明申请

US20030036087A1 Method, system, and computer software for the presentation and storage of analysis results 有权
标题翻译：方法，系统和计算机软件，用于呈现和存储分析结果
公开(公告)号：US20030036087A1
公开(公告)日：2003-02-20
申请号：US10219882
申请日：2002-08-15
申请人： Affymetrix, Inc. a Corporation Organized under the laws of Delaware
发明人： Shantanu Kaushikkar , Teresa Webster , Rui Mei , Linda McAllister
IPC分类号： C12Q001/68 , G06F019/00 , G01N033/48 , G01N033/50 , C07H021/04 , G06K009/00
CPC分类号： G06F19/20 , B01J2219/007 , G01N2035/00158 , G06F19/18 , G06F19/26 , Y10S707/99943
摘要： A computer program product, and related systems and methods, are described that processes emission intensity data corresponding to probes of a biological probe array. The computer program includes a genotype and statistical analysis manager that determines absolute or relative expression values based, at least in part, on a statistical measure of the emission intensity data and at least one user-selectable statistical parameter. The analysis manager may also determine genotype calls for one or more probes based, at least in part, on the emission intensity data, The analysis manager may further display the absolute or relative expression values based, at least in part, on at least one user-selectable display parameter and/or a measure of normalized change between genotype calls. The measure of normalized change may be based, at least in part, on a comparison of genotype calls and a reference value.
摘要翻译：描述了计算机程序产品以及相关系统和方法，其处理对应于生物探针阵列的探针的发射强度数据。所述计算机程序包括基因型和统计分析管理器，所述基因型和统计分析管理器至少部分地基于所述发射强度数据和至少一个用户可选择的统计参数的统计度量来确定绝对或相对表达值。至少部分地基于发射强度数据，分析管理器还可以确定基于一个或多个探针的基因型呼叫。分析管理器还可以至少部分地基于至少一个用户来显示绝对或相对表达值 - 可选择的显示参数和/或基因型呼叫之间的归一化变化的度量。归一化变化的度量可以至少部分地基于基因型呼叫和参考值的比较。

6. 发明申请

US20060253035A1 Methods and Devices for Reading Microarrays 有权
标题翻译：读取微阵列的方法和设备
公开(公告)号：US20060253035A1
公开(公告)日：2006-11-09
申请号：US11379641
申请日：2006-04-21
申请人： David Stern
发明人： David Stern
IPC分类号： A61B6/00
CPC分类号： G01N21/6428 , G01N21/6452 , G01N21/6456
摘要： An embodiment of a system for acquiring images of a probe array is described that comprises a first light emitting diode that provides light comprising a first range of wavelengths outside of an excitation spectrum; a second light emitting diode that provides light comprising a second range of wavelengths inside of the excitation spectrum; and a detector that detects one or more wavelengths in the first range of wavelengths, wherein the first range of wavelengths comprise light wavelengths emitted from fluorescent molecules associated with one or more probes of the probe array in response to the second range of wavelengths and wavelengths reflected from one or more reflective elements associated with the probe array.
摘要翻译：描述了一种用于获取探针阵列的图像的系统的实施例，其包括提供包含激发光谱外的第一波长范围的光的第一发光二极管; 第二发光二极管，其提供包含激发光谱内的第二波长范围的光; 以及检测器，其检测所述第一波长范围中的一个或多个波长，其中所述第一波长范围包括响应于所述第二波长和波长范围反射的与所述探针阵列的一个或多个探针相关联的荧光分子发射的光波长来自与探针阵列相关联的一个或多个反射元件。

7. 发明申请

US20040012676A1 System, method, and product for scanning of biological materials 有权
标题翻译：用于生物材料扫描的系统，方法和产品
公开(公告)号：US20040012676A1
公开(公告)日：2004-01-22
申请号：US10389194
申请日：2003-03-14
申请人： Affymetrix, Inc., a Corporation Organized under the Laws of Delaware
发明人： Nathan K. Weiner , Patrick J. Odoy , Eric Schultz , Mark Jones , James Overbeck , Herman Deweerd , David A. Stura , Albert Bukys , Tim Woolaver , Thomas P. Regan , David Bradbury , Eric Earl McKenzie , Roger DiPaolo , Christopher Miles , Joel Katz , Ksenia Oleink-Ovod
IPC分类号： H04N003/16
CPC分类号： G01N21/6428 , G01N21/253 , G01N21/6452 , G01N2021/6471
摘要： An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values.
摘要翻译：描述了扫描系统的实施例，其包括将激发光束引导到探针阵列的光学元件，响应于激发光束接收反射光强数据的检测器，其中反射光强度数据响应于光学元件和探针阵列，调整相对于探针阵列的方向上的聚焦距离的传输框架，基于至少两个聚焦距离的反射强度数据的特性确定最佳聚焦距离的自动对焦器，其中检测器进一步基于在最佳焦点平面上设置在探针阵列上的多个探针特征的检测到的发射来接收像素强度值，以及图像生成器，其将每个像素强度值与探针阵列的至少一个图像像素位置相关联一个或多个位置校正值。

8. 发明申请

US20040006431A1 System, method and computer software product for grid placement, alignment and analysis of images of biological probe arrays 审中-公开
标题翻译：用于生物探针阵列图像的网格放置，对准和分析的系统，方法和计算机软件产品
公开(公告)号：US20040006431A1
公开(公告)日：2004-01-08
申请号：US10391882
申请日：2003-03-19
申请人： Affymetrix, Inc., a Corporation Organized under the laws of Delaware
发明人： Daniel M. Bartell , Xiaojun Di , Wei-Min Liu , Shantanu V. Kaushikkar
IPC分类号： G06F019/00 , G01N033/48 , G01N033/50
CPC分类号： G06T7/33 , G16B25/00
摘要： A system is described that associates grids with a probe array image based upon a positional placement of one or more control features, aligns the grids with one or more pixels based upon a metric value determined by one or more characteristics of the one or more pixels, and generates cell intensity values. The system may also associate grids with a probe array image based upon a positional placement of one or more control features, determine a ratio of pixel intensity values associated with areas of the grid and adjust the positional association of the grid based upon the determined ratio. The system may also associate grids with a probe array image based upon a positional placement of one or more control features and generate cell intensity values based upon weighted pixel intensity values associated with areas of the grid.
摘要翻译：描述了一种系统，其基于一个或多个控制特征的位置放置将网格与探针阵列图像相关联，基于由一个或多个像素的一个或多个特征确定的度量值将网格与一个或多个像素对准，并生成单元格强度值。该系统还可以基于一个或多个控制特征的位置布置将网格与探针阵列图像相关联，确定与网格的区域相关联的像素强度值的比率，并且基于所确定的比例来调整网格的位置关联。系统还可以基于一个或多个控制特征的位置放置将网格与探针阵列图像相关联，并且基于与网格的区域相关联的加权像素强度值生成单元强度值。

9. 发明申请

US20040138821A1 System, method, and computer software product for analysis and display of genotyping, annotation, and related information 审中-公开
标题翻译：系统，方法和计算机软件产品，用于分析和显示基因分型，注释和相关信息
公开(公告)号：US20040138821A1
公开(公告)日：2004-07-15
申请号：US10657481
申请日：2003-09-08
申请人： Affymetrix, Inc. a Corporation Organized under the laws of Delaware
发明人： Richard Chiles , Muniyappa Prakash
IPC分类号： G01N033/48 , G06G007/48
CPC分类号： G16B45/00 , G16B20/00 , G16B25/00
摘要： A method for displaying genotype information associated with probe array experiments is described that includes the acts of receiving sets of emission intensity data, wherein each set of emission intensity data includes emission intensity values each associated with a probe disposed upon a probe array; generating genotype calls, wherein each of the genotype calls is based, at least in part, upon the emission intensity values; assembling the genotype calls into one or more genotype data sets; and displaying each of the genotype data sets in one or more panes of a graphical user interface.
摘要翻译：描述了用于显示与探针阵列实验相关联的基因型信息的方法，其包括接收发射强度数据集的动作，其中每组发射强度数据包括与设置在探针阵列上的探针相关联的发射强度值; 生成基因型呼叫，其中每个基因型呼叫至少部分地基于发射强度值; 将基因型调用组合成一个或多个基因型数据集; 以及在图形用户界面的一个或多个窗格中显示每个基因型数据集。

10. 发明申请

US20040012633A1 System, method, and computer program product for dynamic display, and analysis of biological sequence data 审中-公开
标题翻译：用于动态显示的系统，方法和计算机程序产品，以及生物序列数据的分析
公开(公告)号：US20040012633A1
公开(公告)日：2004-01-22
申请号：US10423404
申请日：2003-04-25
申请人： Affymetrix, Inc., a Corporation Organized under the laws of Delaware
发明人： Gregg A. Helt
IPC分类号： G09G005/00
CPC分类号： G16B45/00
摘要： A system for providing an interactive interface for biological sequence information is described that includes a GUI manager to manage and display graphical elements, each associated with a user selection of one or more biological sequences, in the panes of a graphical user interface, where the one or more biological sequences includes a chromosome sequence; and one or more biological sequence tools that provide one or more tools to process information based upon a user selection of at least one of the graphical elements.
摘要翻译：描述了一种用于提供用于生物序列信息的交互界面的系统，其包括GUI管理器，用于管理和显示图形元素，每个图形元素与图形用户界面的窗格中的一个或多个生物序列的用户选择相关联，其中一个或更多的生物学序列包括染色体序列; 以及一个或多个生物序列工具，其提供一个或多个工具以基于用户选择至少一个图形元素来处理信息。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式