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    • 81. 发明申请
    • USE OF BIOCOMPATIBLE POLYMERS FOR THE PREPARATION OF A COMPOSITION OR A MEDICAL DEVICE
    • 用于制备组合物或医疗设备的生物易燃聚合物的使用
    • US20140301972A1
    • 2014-10-09
    • US14308574
    • 2014-06-18
    • Denis BarritaultORGANES TISSUS REGENERATION REPARATION REPLACEMENT - OTR3
    • Denis BARRITAULTVeronique Barbier-Chassefiere
    • C08B3/00A61K8/73A61Q19/00C08G63/06A61K8/85A61Q19/02C08B37/02C08B37/00
    • C08B3/00A61K8/73A61K8/731A61K8/85A61K31/737A61K31/795A61Q19/00A61Q19/02C08B37/0009C08B37/0021C08G63/06
    • The invention relates to a biocompatible polymer having general formula (I) AaXxYy, wherein: A denotes a monomer; X denotes an RCOOR′ group; Y denotes an O or N-sulphonate group which is fixed to A and which has either formula —ROS03R′ or —RNS03R′ in which R denotes an optionally branched and/or unsaturated aliphatic hydrocarbon chain which can contain one or more aromatic rings and R′ denotes a hydrogen atom or a cation; a denotes the number of monomers; x denotes the rate of substitution of the A monomers by the X groups; and y denotes the rate of substitution of the A monomers by the Y groups. More specifically, the invention relates to the use of said biocompatible polymers for the preparation of a pharmaceutical, dermatological or cosmetic composition or a medical device, which are intended to prevent, relieve and/or treat discomfort, distress, itches, irritations and/or pain and/or to protect tissues against same. In addition, in certain cases, the use of said biocompatible polymers for pain treatment can impact on the actual curing of certain diseases. Significant improvements and even cures have been observed in relation to chronic and painful diseases that are associated with alterations in the extracellular matrix regardless of the origin thereof.
    • 本发明涉及具有通式(I)A a X x Y y的生物相容性聚合物,其中:A表示单体; X表示RCOOR'基团; Y表示固定在A上并具有式-ROS03R'或-RNS03R'的O或N-磺酸盐基团,其中R表示可含有一个或多个芳环的任选支链和/或不饱和脂族烃链,R '表示氢原子或阳离子; a表示单体数目; x表示X单体的A单体的取代率; y表示Y单体由Y基取代的比例。 更具体地,本发明涉及所述生物相容性聚合物用于制备药物,皮肤病学或化妆品组合物或医疗装置的用途,其旨在防止,缓解和/或治疗不适,遇险,瘙痒,刺激和/或 疼痛和/或保护组织免受同样的影响。 此外,在某些情况下,使用所述生物相容性聚合物进行疼痛治疗可能会影响某些疾病的实际固化。 对于与细胞外基质的改变相关的慢性和疼痛性疾病,观察到显着的改善甚至治愈,不管其来源如何。
    • 83. 发明授权
    • Glycerin polyesters with terminal modification
    • 甘油聚酯末端改性
    • US08808677B1
    • 2014-08-19
    • US13998740
    • 2013-12-02
    • Thomas George O'Lenick
    • Thomas George O'Lenick
    • A61Q5/12C07F7/08A61K8/85A61Q19/00
    • A61K8/85A61Q19/00C08G63/12C08G63/123C08G63/20C08G63/553
    • The present invention is directed to a series of functionalized glycerin based polymers that have been designed to have very specific substitution patterns, herein referred to as regio-specific substitution (RSS). We have surprisingly found that by linking triglycerides into polymer backbones and controlling the location of the different alkyl groups along that backbone, the performance and structure can be fine tuned. The properties of these polymers can be controlled and tuned by judicial control of the polymerization conditions, specifically by employing the use of mono-functional monomers. This polymer will has “compartments” of solid and liquid pendant group domains if the proper pendant groups are chosen. This unique multi-dimensional, high definition polymer will have very unique physical properties, including unique shear and flow behaviors. These polymers will provide outstanding and unique skin feels when used in cosmetic applications.
    • 本发明涉及一系列功能性甘油基聚合物,其被设计为具有非常特定的取代模式,这里称为区域特异性取代(RSS)。 我们惊奇地发现,通过将甘油三酯连接成聚合物主链并控制不同烷基沿该主链的位置,可以调节性能和结构。 这些聚合物的性质可以通过对聚合条件的司法控制进行控制和调节,特别是通过使用单官能单体。 如果选择适当的侧基,该聚合物将具有固体和液体侧基组域的“隔间”。 这种独特的多维高清聚合物将具有非常独特的物理性质,包括独特的剪切和流动行为。 当用于化妆品应用时,这些聚合物将提供卓越和独特的皮肤感觉。
    • 87. 发明申请
    • SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYESTER
    • 包含超紫外线吸收聚酯的SUNSCREEN组合物
    • US20140004058A1
    • 2014-01-02
    • US13710546
    • 2012-12-11
    • JOHNSON & JOHNSON CONSUMER COMPANIES, INC.
    • Susan DalyRocco Vincent Burgo
    • A61K8/85A61Q17/04
    • A61K8/85A61K8/062A61K8/55A61Q17/04
    • Compositions including a discontinuous oil phase substantially homogeneously dispersed in a continuous water phase, the oil phase including a sunscreen agent that includes a UV-absorbing polyester in an amount effective to provide the composition with an SPF of about 10 or greater and which is the polymerization reaction product of monomers including a UV-absorbing triazole, a diester, a diol and a tetrol polyol; and an oil-in water emulsifier component including an anionic oil-in-water emulsifier in an amount such that the composition includes about 0.3 percent or more by weight to about 3 percent by weight of the anionic oil-in-water emulsifier, where the composition is substantially free of a non-polymeric UV-absorbing sunscreen agent and has an SPF of less than 2 in the absence of the UV-absorbing polyester.
    • 包含基本均匀分散在连续水相中的不连续油相的组合物,所述油相包括防晒剂,其包含有效提供组合物的SPF为约10或更大并且为聚合的UV吸收性聚酯 包括紫外线吸收三唑,二酯,二醇和四元醇的单体的反应产物; 以及包含阴离子水包油乳化剂的含水包水乳化剂组分,其量使得所述组合物占阴离子水包油乳化剂的约0.3重量%至约3重量%,其中 组合物基本上不含非聚合物紫外线吸收防晒剂,并且在不存在UV吸收性聚酯的情况下具有小于2的SPF。