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81. 发明申请

US20150076008A1 BIOSENSOR DEVICE AND SYSTEM 有权
标题翻译：生物传感器设备和系统
公开(公告)号：US20150076008A1
公开(公告)日：2015-03-19
申请号：US14387354
申请日：2013-03-28
申请人： DNA Electronics Ltd.
发明人： Panteleimon Athanasiou , Alpesh Patel , David Whitaker , Hua Bai , John Palmer-Felgate , Daniel Coomber-Alford , Jessica Fisher , Chad Schenider , Alex Flamm , Ben Lane , Sam Reed
IPC分类号： G01N27/327
CPC分类号： G01N27/327 , B01F5/0647 , B01F5/065 , B01F13/0059 , B01F2215/0037 , B01F2215/0431 , B01L3/502 , B01L3/5025 , B01L3/502715 , B01L3/502723 , B01L3/502738 , B01L3/5029 , B01L3/50851 , B01L3/50853 , B01L7/52 , B01L2200/0684 , B01L2200/0689 , B01L2200/16 , B01L2300/048 , B01L2300/0609 , B01L2300/0636 , B01L2300/0645 , B01L2300/0819 , B01L2300/0867 , B01L2300/0883 , B01L2300/1827 , B01L2400/0478 , B01L2400/0638 , B01L2400/0677 , G01N27/4145 , G01N27/4148
摘要： A plug side surface of a plug housing is provided with a claw portion. The claw portion includes a plug lock surface facing in a direction away from a connector mounting surface. Each assistant fitting of a receptacle connector includes a receptacle lock surface that faces in a direction approaching the connector mounting surface and is opposed to the plug lock surface in a mated state. The plug lock surface includes a lock maintaining surface and an unlocking surface. Assuming that an angle formed between a reference plane and the lock maintaining surface is a lock maintaining angle and an angle formed between the reference plane and the unlocking surface is an unlocking angle, the lock maintaining angle is smaller than the unlocking angle.
摘要翻译：插头壳体的插头侧表面设有爪部。爪部包括面向远离连接器安装表面的方向的插头锁定表面。插座连接器的每个辅助配件包括接收器锁定表面，其面向接近连接器安装表面的方向，并且在配合状态下与插头锁定表面相对。插头锁定表面包括锁定保持表面和解锁表面。假设在参考平面和锁定保持表面之间形成的角度是锁定保持角度，并且在基准平面和解锁表面之间形成的角度是解锁角度，锁定保持角度小于解锁角度。

82. 发明申请

US20150072402A1 BIOSENSOR, BIOSENSOR CHIP AND BIOSENSOR DEVICE 有权
公开(公告)号：US20150072402A1
公开(公告)日：2015-03-12
申请号：US14512243
申请日：2014-10-10
申请人： PANASONIC HEALTHCARE HOLDINGS CO., LTD.
发明人： Hiroya Ueno , Junji Nakatsuka
IPC分类号： G01N27/327 , G01R19/00 , G01N27/30
CPC分类号： G01N27/3271 , C12Q1/001 , G01N27/30 , G01N27/307 , G01N27/327 , G01N27/3272 , G01N27/3273 , G01N27/416 , G01R19/0092
摘要： A biosensor includes a working electrode 101, a counter electrode 102 opposing the working electrode 101, a working electrode terminal 103 and a working electrode reference terminal 10 connected to the working electrode 101 by wires, and a counter electrode terminal 104 connected to the counter electrode 102 by a wire. By employing a structure with at least three electrodes, it is possible to assay a target substance without being influenced by the line resistance on the working electrode side.

83. 发明申请

US20150060271A1 BIOSENSOR, BIOSENSOR CHIP AND BIOSENSOR DEVICE 有权
公开(公告)号：US20150060271A1
公开(公告)日：2015-03-05
申请号：US14512817
申请日：2014-10-13
申请人： PANASONIC HEALTHCARE HOLDINGS CO., LTD.
发明人： Hiroya Ueno , Junji Nakatsuka
IPC分类号： G01N27/327
CPC分类号： G01N27/3271 , C12Q1/001 , G01N27/30 , G01N27/307 , G01N27/327 , G01N27/3272 , G01N27/3273 , G01N27/416 , G01R19/0092
摘要： A biosensor includes a working electrode 101, a counter electrode 102 opposing the working electrode 101, a working electrode terminal 103 and a working electrode reference terminal 10 connected to the working electrode 101 by wires, and a counter electrode terminal 104 connected to the counter electrode 102 by a wire. By employing a structure with at least three electrodes, it is possible to assay a target substance without being influenced by the line resistance on the working electrode side.

84. 发明申请

US20150047977A1 AUTOMATIC CODING DEVICE, BIOSENSOR WITH SAME AND MANUFACTURING METHOD THEREFOR 审中-公开
标题翻译：自动编码装置，生物传感器及其制造方法
公开(公告)号：US20150047977A1
公开(公告)日：2015-02-19
申请号：US14389698
申请日：2013-01-30
申请人： LEADWAY (HK) LIMITED
发明人： Tao Liu , Huanxi Ge , Chia-Lin Wang , Yun Ye
IPC分类号： G01N27/327 , H05K3/02
CPC分类号： G01N27/327 , G01N33/48771 , G01N35/00693 , G01N2035/00782 , G01N2035/00811 , H05K3/027 , Y10T29/49155 , Y10T29/49156
摘要： The present invention provides an automatic encoding device including a first electrode, a second electrode, and a third electrode. The first electrode and the second electrode are connected through a connecting point, so that an electric parameter between the first electrode and the second electrode changes according to a parameter needing to be corrected. The present invention further provides a method for applying the automatic encoding device to various biosensors and a method for manufacturing the automatic encoding device. Positions and the number of contacts for connecting the automatic encoding device and a detection system are fixed. Therefore, connection sites on the detection system are effectively utilized. On the other hand, the automatic encoding device in the present invention can provide different parameter information by only changing the positions of the connecting points on the electrodes, the process is simple and stable, and the probability of human errors is reduced.
摘要翻译：本发明提供一种包括第一电极，第二电极和第三电极的自动编码装置。第一电极和第二电极通过连接点连接，使得第一电极和第二电极之间的电参数根据需要校正的参数而改变。本发明还提供了一种将自动编码装置应用于各种生物传感器的方法和用于制造自动编码装置的方法。用于连接自动编码装置和检测系统的位置和数量是固定的。因此，有效利用检测系统上的连接站点。另一方面，本发明的自动编码装置可以通过仅改变电极上的连接点的位置来提供不同的参数信息，处理简单且稳定，人为错误的可能性降低。

85. 发明申请

US20150021207A1 NEAR-FIELD-COMMUNICATION OR RFID BASED ELECTROCHEMICAL BIOSENSOR AND METHOD FOR AN INGREDIENT MEASUREMENT USING THEREOF 审中-公开
标题翻译：近场通信或基于RFID的电化学生物传感器及其使用的成分测量方法
公开(公告)号：US20150021207A1
公开(公告)日：2015-01-22
申请号：US14017030
申请日：2013-09-03
申请人： Center for Integrated Smart Sensors Foundation
发明人： Chong-Min KYUNG , Hyun Tae CHO , Seung Ro LEE
IPC分类号： G01N27/327
CPC分类号： A61B5/002 , A61B5/0002 , A61B5/14532 , A61B5/1477 , A61B5/150022 , A61B5/150213 , A61B5/150358 , A61B5/15087 , A61B5/157 , A61B2560/0214 , A61B2560/0285 , A61B2562/08 , G01N27/327 , G01N27/3272 , G01N33/48792 , H04B5/0031 , H04B5/0037 , H04Q9/00
摘要： Disclosed herein are a near-field-communication or a Radio-Frequency Identification (RFID) based electrochemical biosensor capable of measuring an ingredient by being inter-worked with a wireless communication device such as a smartphone and a method for an ingredient measurement using thereof. The near field communication or radio-frequency identification based electrochemical biosensor, includes: a casing having a specimen introduction channel formed therein; an ingredient measurement electrode disposed in the casing and measuring a specific ingredient of a specimen; a reaction reagent portion disposed in the casing and reacting with the specimen; a specimen recognition electrode disposed in the casing and recognizing the introduction of the specimen; an antenna transmitting and receiving signals and power to and from a smart device or a tester; and a control integrated circuit (IC) chip controlling the ingredient measurement electrode, the specimen recognition electrode, and the antenna.
摘要翻译：本文公开了一种近场通信或基于射频识别（RFID）的电化学生物传感器，其能够通过与诸如智能电话的无线通信设备和使用其的成分测量的方法进行互动来测量成分。近场通信或基于射频识别的电化学生物传感器包括：壳体，其中形成有试样引入通道; 成分测量电极，设置在壳体中并测量样品的特定成分; 反应试剂部，其设置在所述壳体内并与所述试样反应; 标本识别电极，其设置在所述壳体内并识别所述样本的引入; 天线向智能设备或测试仪发送和接收信号和电源; 以及控制成分测量电极，样本识别电极和天线的控制集成电路（IC）芯片。

86. 发明申请

US20150021179A1 ELECTROCHEMICAL STRIP AND MANUFACTURING METHOD THEREOF 有权
标题翻译：电化学条纹及其制造方法
公开(公告)号：US20150021179A1
公开(公告)日：2015-01-22
申请号：US14506378
申请日：2014-10-03
申请人： YUTEK TRONIC INC.
发明人： Chuan-Hsing HUANG
IPC分类号： G01N27/30 , C23C18/32 , G01N27/327 , C23C18/31 , C23C18/16 , C23C18/24 , C23C18/42
CPC分类号： C23C18/1651 , C23C18/1641 , C23C18/24 , C23C18/31 , C23C18/32 , C23C18/42 , G01N27/307 , G01N27/327 , G01N27/3272
摘要： An electrochemical strip is disclosed. The electrochemical strip includes a substrate and an electrode deposited on the substrate. The electrode includes a conductive paste layer, a first metal layer, a second metal layer, a third metal layer, and a fourth metal layer. The conductive paste is made of a material selected from the group consisting of copper paste, nickel paste, silver paste, and silver-carbon paste. The first metal layer is made of a group VIII metal. The second metal layer is made of nickel. The third metal layer is made of a group VIII metal. The fourth metal layer is made of a material selected from the group consisting of palladium, gold, and platinum.
摘要翻译：公开了一种电化学条带。电化学条带包括沉积在基底上的基底和电极。电极包括导电浆料层，第一金属层，第二金属层，第三金属层和第四金属层。导电膏由选自铜膏，镍膏，银膏和银 - 碳糊的材料制成。第一金属层由VIII族金属制成。第二金属层由镍制成。第三金属层由VIII族金属制成。第四金属层由选自钯，金和铂的材料制成。

87. 发明申请

US20140367255A1 INTERDIGITATED ARRAY AND METHOD OF MANUFACTURE 有权
标题翻译： INTERDIGITATED ARRAY AND METHODS MANUFACTURE
公开(公告)号：US20140367255A1
公开(公告)日：2014-12-18
申请号：US14359792
申请日：2012-11-19
申请人： Siemens Healthcare Diagnostics Inc.
发明人： Jennifer A. Samproni
IPC分类号： G01N27/327 , H05K3/32
CPC分类号： G01N27/327 , G01N27/127 , H05K3/321 , Y10T29/49155
摘要： An automated feed manufacturing product is disclosed. The automated feed manufacturing product is provided with a flexible substrate having a plurality of card zones with the card zones defining sensing areas with sensor units formed within the sensing areas. The sensor units have a first electrode having first fingers, and a second electrode having second fingers and with the first fingers interleaved with the second fingers and with the first fingers spaced away from the second fingers. The sensor units also comprising biomolecule receptors on the flexible web between the first electrode and the second electrode such that a physical property of the first electrode relative to the second electrode is effected upon one or more of the biomolecule receptors binding to a biomolecule. The automated feed manufacturing product can be formed as a continuous web, or discrete sheets formed using a sheet feeder that picks up and processes the discrete sheets.
摘要翻译：公开了一种自动进料制造产品。自动进料制造产品设置有具有多个卡片区域的柔性基底，其中卡片区域具有形成在感测区域内的传感器单元的感测区域。传感器单元具有具有第一指状物的第一电极和具有第二指状物的第二电极，并且第一指状物与第二指状物交错并且第一指状物与第二指状物间隔开。所述传感器单元还包括位于第一电极和第二电极之间的柔性网上的生物分子受体，使得第一电极相对于第二电极的物理性质受一种或多种生物分子受体结合生物分子的影响。自动进料制造产品可以形成为连续的卷材，或者使用拾取和处理离散片材的片材进给器形成的离散片材。

88. 发明申请

US20140353153A1 Preparation and Maintenance of Sensors 审中-公开
标题翻译：传感器的准备与维护
公开(公告)号：US20140353153A1
公开(公告)日：2014-12-04
申请号：US14459643
申请日：2014-08-14
申请人： Edwards Lifesciences Corporation
发明人： Michael Higgins , Mark A. Konno , Todd Fjield
IPC分类号： G01N27/416
CPC分类号： G01N27/416 , A61B5/14532 , A61B5/1486 , A61B5/1495 , A61B2562/242 , G01N27/327 , G01N33/4875
摘要： Apparatus and methods are described for preparing, maintaining, and stabilizing sensors. The apparatus and methods for preparing sensors for use are utilized in advance of the sensor being removed from a sealed, sterilized package. The apparatus include packaging materials having electrical circuits capable of stabilizing a sensor to prepare the sensor for use. The methods for preparing a sensor for use includes methods of providing a solution to a sterilized packaging that contains a sensor connected to a sensor activating circuit, activating the circuit, and allowing the sensor to stabilize. These methods can be performed without compromising the packaging. The apparatus for stabilizing a sensor that is in use include a circuit connectable to the sensor that provides a signal to the sensor that prevents the sensor from becoming destabilized when disconnected from a monitoring device.
摘要翻译：描述了用于制备，维护和稳定传感器的装置和方法。在将传感器从密封的无菌包装中取出之前，使用用于制备用于制备传感器的装置和方法。该装置包括具有能够稳定传感器以制备传感器以供使用的电路的封装材料。制备用于使用的传感器的方法包括向包括连接到传感器启动电路的传感器，激活电路并允许传感器稳定的灭菌包装提供解决方案。这些方法可以在不损害包装的情况下进行。用于稳定正在使用的传感器的装置包括可连接到传感器的电路，该传感器向传感器提供信号，以防止当与监视装置断开时传感器变得不稳定。

89. 发明申请

US20140342462A1 MEASUREMENT OF LACTIC ACID IN BIOLOGICAL FLUIDS 有权
标题翻译：生物流体中酸乳酸的测定
公开(公告)号：US20140342462A1
公开(公告)日：2014-11-20
申请号：US14345595
申请日：2012-09-25
申请人： POWER FIT S.r.l.
发明人： Emilia Bramanti , Fabrizio Zuccnini , Massimo Onor , Vincenzo Di Muro
IPC分类号： G01N33/52 , G01N21/25 , G01N21/33 , G01N27/327
CPC分类号： G01N27/4168 , G01N21/251 , G01N21/33 , G01N21/6428 , G01N21/76 , G01N21/78 , G01N21/8483 , G01N27/327 , G01N27/3272 , G01N27/3277 , G01N33/48707 , G01N33/52 , Y10T436/201666
摘要： We propose a procedure for the determination of lactic acid or lactate in biological fluids, which is simple and low cost with respect to the known methodologies. This procedure can be used by unskilled personnel and it can be implemented in disposable test strips and portable measure devices. The procedure is based on the photochemical reaction of lactic acid with Fe(III), which is reduced to Fe(II) when irradiated with UV light. The Fe(II), produced proportionally to the amount of lactate in the sample, is determined electrochemically or using its reaction with a colored complexing agent, such as 1,10-phenanthroline, and determined by spectrophotometry. This method is advantageous both for the low cost of the reagents employed, and for their short and long term stability.
摘要翻译：我们提出了一种测定生物体液中乳酸或乳酸盐的方法，相对于已知方法而言，这是简便且成本低的方法。该程序可以由非熟练人员使用，并且可以在一次性测试条和便携式测量装置中实现。该程序基于乳酸与Fe（III）的光化学反应，当用UV光照射时，其被还原成Fe（II）。通过电化学方法或使用其与有色络合剂如1,10-菲咯啉的反应测定样品中与乳酸盐的量成比例的Fe（II），并通过分光光度法测定。该方法对于所用试剂的低成本以及它们的短期和长期稳定性都是有利的。

90. 发明申请

US20140330100A1 CARBON NANOSTRUCTURE ELECTROCHEMICAL SENSOR AND METHOD 审中-公开
标题翻译：碳纳米结构电化学传感器及方法
公开(公告)号：US20140330100A1
公开(公告)日：2014-11-06
申请号：US14344018
申请日：2012-09-10
申请人： Chunhong Li , David J. Ruggieri
发明人： Chunhong Li , David J. Ruggieri
IPC分类号： G01N27/26 , A61B5/145 , A61B5/1486 , G01N27/30 , G01N27/327
CPC分类号： G01N27/26 , A61B5/14539 , A61B5/1486 , B82Y30/00 , B82Y40/00 , B82Y99/00 , C01B32/174 , G01N27/302 , G01N27/327 , H01M8/04671 , Y10S977/742 , Y10S977/75 , Y10S977/752 , Y10S977/847 , Y10S977/902
摘要： Carbon nanostructures may be protected and functionalized using a layer-by-layer method whereby functional groups on the carbon nanostructure surface may be further derivatized to incorporate additional functional moieties. Exemplary moieties include redox mediator molecules, crown ethers, catalysts, boric acids, carbohydrates, oligonucleotides, DNA or RNA aptamers, peptide aptamers, proteins such as enzymes and antibodies, quantum dots and nanoparticles, cells, cell organelles, or other cellular components. The density of functional groups or functional moieties on carbon nanostructure surfaces may also be controlled as well as the degree of surface hydrophilicity of the nanostructure. Carbon nanostructures functionalized using such a layer-by-layer method may be used to disperse, sort, separate and purify carbon nanostructures and may be used as sensing elements such as voltammetric, amperometric, and potentiometric pH sensors or as biometric sensing elements and electrodes and intracorporeal sensors and electrode.
摘要翻译：可以使用逐层方法来保护和官能化碳纳米结构，由此碳纳米结构表面上的官能团可被进一步衍生化以引入额外的官能部分。示例性部分包括氧化还原介体分子，冠醚，催化剂，硼酸，碳水化合物，寡核苷酸，DNA或RNA适体，肽适体，诸如酶和抗体的蛋白质，量子点和纳米颗粒，细胞，细胞器细胞器或其它细胞组分。也可以控制碳纳米结构表面上的官能团或官能团的密度以及纳米结构的表面亲水性程度。使用这种逐层方法功能化的碳纳米结构可以用于分散，分类，分离和净化碳纳米结构，并且可以用作感测元件，例如伏安法，电流计和电位pH传感器，或者用作生物测定元件和电极，体内传感器和电极。

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