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81. 发明申请

US20160326695A1 PROCESS FOR REFINING CHEMICALS FROM PULP AND PAPER MILL EFFLUENT 审中-公开
标题翻译：从纸浆和纸泥浆中精炼化学品的方法
公开(公告)号：US20160326695A1
公开(公告)日：2016-11-10
申请号：US15181363
申请日：2016-06-13
申请人： Her Majesty the Queen in Right of Canada, as represented by the Minister of Environment
发明人： Craig Brennan Milestone , Deborah L. MacLatchy , L. Mark Hewitt
IPC分类号： D21C11/00 , C07C41/38 , C07C29/76 , C07C29/86 , C07C45/79 , C07C45/80 , C07C7/00 , C07C7/10 , C02F1/44 , C02F1/04 , B01D61/02 , B01D11/04 , B01D15/42 , B01D1/26 , C07C41/36
CPC分类号： C07B63/00 , B01D1/26 , B01D11/00 , B01D11/0426 , B01D11/0492 , B01D15/426 , B01D61/00 , B01D61/025 , B01D2311/08 , B01D2311/18 , B01D2311/2626 , B01D2311/2649 , B01D2311/2676 , C02F1/00 , C02F1/048 , C02F1/441 , C02F2103/28 , C07C7/005 , C07C7/10 , C07C7/12 , C07C29/76 , C07C29/86 , C07C41/36 , C07C41/38 , C07C45/79 , C07C45/80 , C07C2602/28 , D21C11/00 , D21C11/0007 , C07C33/02 , C07C43/23 , C07C33/14 , C07C47/02
摘要： A process for isolating at least one target compound, such as manool, geranyl linalool, ethyl guaiacol, eugenol, veratraldehyde, squalene, terpin, cholesterol, beta-sitosterol, campesterol, stigmasterol, stigmastenol and dehydroabietic acid, from biomass, the process including steps of: obtaining a condensate from a recovery evaporator, a reverse osmosis retentate of a condensate of a pulp and paper mill, or both, the condensate, retentate or both being substantially free of higher molecular weight (approximately >1000 Da) cellulose and/or lignin and/or lignin-derived material; optionally pH adjusting and filtering the condensate to collect insoluble material; extracting the condensate, the collected insoluble material, or both, with solid phase extraction (SPE), liquid-liquid extraction or solid-liquid extraction to produce an extract containing the at least one target compound; and optionally purifying the extract containing the at least one target compound by thermal fractionation, chromatographic separation, recrystallization ion exchange, chelation, adsorption/desorption, lyophilization and sublimation or combinations thereof. The method is particularly useful for isolating the target compounds from wastewaters produced in a kraft pulp and paper mill, especially from recovery evaporator condensates produced during the treatment of black liquor.
摘要翻译：一种从生物质中分离至少一种目标化合物如甘露醇，芳香醇，乙基愈创木酚，丁子香酚，藜芦醛，角鲨烯，萜品烯，胆固醇，β-谷甾醇，菜油甾醇，豆甾醇，斯曲马斯汀和脱氢松香酸的方法，：从回收蒸发器获得冷凝物，纸浆和造纸厂的冷凝物的反渗透保留物或两者，冷凝物，滞留物或两者基本上不含较高分子量（约> 1000Da）的纤维素和/或木质素和/或木质素衍生物质; 任选调节pH值并过滤冷凝液以收集不溶物质; 用固相萃取（SPE），液 - 液萃取或固 - 液萃取提取冷凝物，收集的不溶物或两者，以产生含有至少一种目标化合物的提取物; 任选地通过热分级，色谱分离，重结晶离子交换，螯合，吸附/解吸，冻干和升华或其组合纯化含有至少一种目标化合物的提取物。该方法特别适用于从牛皮纸浆和造纸厂中生产的废水中分离出目标化合物，特别是在处理黑液期间产生的回收蒸发器冷凝物中。

82. 发明授权

US09469586B2 Production of partially refined waste glycerol 有权
标题翻译：生产部分精制废弃甘油
公开(公告)号：US09469586B2
公开(公告)日：2016-10-18
申请号：US14463635
申请日：2014-08-19
申请人： REG Life Sciences, LLC
发明人： Myong K. Ko , Perry Y. Liao , Simon Li , Fernando A. Sanchez-Riera
IPC分类号： C07C29/86 , C11D19/00
CPC分类号： C07C29/86 , C07C31/225 , C11D19/00
摘要： The disclosure relates to a novel glycerol purification process that produces partially refined waste glycerol for a variety of industrial applications. The disclosure encompasses a salt-containing partially refined glycerol composition that is suitable as a fermentation grade glycerol.
摘要翻译：本公开涉及一种新颖的甘油纯化方法，其产生用于各种工业应用的部分精制的废甘油。本公开内容包括适合作为发酵级甘油的含盐部分精制甘油组合物。

83. 发明申请

US20160200652A1 PRODUCTION OF PARTIALLY REFINED WASTE GLYCEROL 有权
标题翻译：生产部分精制废物甘油
公开(公告)号：US20160200652A1
公开(公告)日：2016-07-14
申请号：US14912104
申请日：2014-08-19
申请人： REG Life Sciences, LLC
发明人： Myong K. Ko , Fernando A. Sanchez-Riera , Simon Li , Perry Y. Liao
IPC分类号： C07C31/22 , C07C29/76 , C07C29/86
CPC分类号： C07C29/88 , C07C29/76 , C07C29/86 , C07C31/225
摘要： The disclosure relates to a novel glycerol purification process that produces partially refined waste glycerol for a variety of industrial applications. The disclosure encompasses a salt-containing partially refined glycerol composition that is suitable as a fermentation grade glycerol.
摘要翻译：本公开涉及一种新颖的甘油纯化方法，其产生用于各种工业应用的部分精制的废甘油。本公开内容包括适合作为发酵级甘油的含盐部分精制甘油组合物。

84. 发明授权

US09315434B2 Method for preparing a composition rich in lutein produced by microalgae 有权
标题翻译：制备富含由微藻产生的叶黄素的组合物的方法
公开(公告)号：US09315434B2
公开(公告)日：2016-04-19
申请号：US14420136
申请日：2013-08-07
申请人： ROQUETTE FRERES
发明人： Philippe Looten , Samuel Patinier , Eric Francais , Michel Perrut , Aurore Satre-Buisson
IPC分类号： C07C29/86 , A23L1/30 , C09B61/00 , C12P23/00 , C07C403/24 , C12N1/06 , A61K31/047
CPC分类号： C07C29/86 , A23L33/10 , A23L33/105 , A23V2002/00 , A61K31/047 , C07C403/24 , C07C2601/16 , C09B61/00 , C12N1/066 , C12P23/00 , Y02P20/544
摘要： The invention relates to a method for preparing a composition rich in lutein produced by microalgae, particularly microalgae belonging to the Chlorella genus, more specifically produced by Chlorella vulgaris, characterized in that said method includes the sequence of the following steps: 1) preparing a cell lysate from the microalgae biomass; 2) treating the lysed microalgae biomass with a polar solvent, preferably ethyl acetate, in order to obtain an oleoresin containing the lutein and the lipids from the initial biomass; 3) extracting the oleoresin obtained in step 2) by means of a non-polar solvent, here a fluid at supercritical pressure, in order to obtain a fraction rich in non-polar lipids, mainly consisting of triglycerides, and an insoluble fraction rich in lutein; and 4) recovering the thus lutein-enriched fraction.
摘要翻译：本发明涉及一种制备富含叶绿体的组合物的方法，所述组合物由微藻特别是属于小球藻属的微藻，特别是小球藻产生，其特征在于所述方法包括以下步骤的顺序：1）制备细胞来自微藻生物质的裂解物; 2）用极性溶剂，优选乙酸乙酯处理裂解的微藻生物质，以获得含有叶黄素和来自初始生物质的脂质的油树脂; 3）通过非极性溶剂（这里是超临界压力的流体）提取步骤2）中获得的油树脂，以获得富含主要由甘油三酸酯组成的非极性脂质的级分和富含叶黄素和4）回收如此富含叶黄素的级分。

85. 发明申请

US20160102035A1 PROCESS FOR THE SEPARATION OF AN ALKYLENE GLYCOL 有权
标题翻译：分离出亚苄基甘露糖的方法
公开(公告)号：US20160102035A1
公开(公告)日：2016-04-14
申请号：US14893273
申请日：2014-05-28
申请人： SHELL OIL COMPANY
发明人： Kai Jürgen FISCHER , Wouter KOOT , Arlette WESENHAGEN , Roel Guillaume Hubertus Leonardus BASTINGS
IPC分类号： C07C41/38 , C07C29/80 , C07C41/42 , C07C29/86
CPC分类号： C07C41/38 , C07C29/80 , C07C29/86 , C07C41/42 , C07C31/202 , C07C43/11
摘要： The invention provides a process for the recovery of an alkylene glycol from an aqueous stream comprising the alkylene glycol and the corresponding dialkylene glycol, said process comprising the steps of providing the aqueous stream comprising the alkylene glycol and the corresponding dialkylene glycol, providing a first solvent stream, combining said aqueous stream comprising the alkylene glycol and the corresponding dialkylene glycol with said first solvent stream and recovering at least a portion of the alkylene glycol by liquid-liquid extraction, wherein said solvent comprises an amine.
摘要翻译：本发明提供了一种从包含亚烷基二醇和相应的二亚烷基二醇的含水物流中回收亚烷基二醇的方法，所述方法包括以下步骤：提供包含亚烷基二醇和相应的二亚烷基二醇的水流，提供第一溶剂将包含亚烷基二醇和相应的二亚烷基二醇的所述含水流与所述第一溶剂流组合并通过液 - 液萃取回收至少一部分亚烷基二醇，其中所述溶剂包含胺。

86. 发明申请

US20160075622A1 PROCESS FOR THE SEPARATION AND PURIFICATION OF A MIXED DIOL STREAM 审中-公开
标题翻译：混合二醇流的分离和纯化方法
公开(公告)号：US20160075622A1
公开(公告)日：2016-03-17
申请号：US14950503
申请日：2015-11-24
申请人： Eastman Chemical Company
发明人： Scott Donald Barnicki
IPC分类号： C07C29/86
CPC分类号： C07C29/86 , B01J31/2409 , B01J2531/0258 , B01J2531/821 , C07C29/149 , C07C29/80 , Y02P20/52 , C07C31/202 , C07C31/205 , C07C31/207
摘要： Disclosed is a process for the purification of a mixed diol stream. The mixed diol stream comprising two-, three-, and four-carbon diols is separated into component diols by extraction with a hydrophobic solvent mixture. The diols recovered in the extractant may be removed from the extractant stream by back extraction with water or by distillation with an azeotrope-forming agent present, preferably an azeotroping agent already present in the extractant mixture.
摘要翻译：公开了一种纯化混合二醇流的方法。包含二，三和四碳二醇的混合二醇料流通过用疏水溶剂混合物萃取分离成组分二醇。在萃取剂中回收的二醇可以通过用水反萃取或用存在的共沸物形成剂，优选已经存在于萃取剂混合物中的共沸剂进行蒸馏，从萃取剂流中除去。

87. 发明申请

US20160052847A1 PRODUCTION OF PARTIALLY REFINED WASTE GLYCEROL 有权
公开(公告)号：US20160052847A1
公开(公告)日：2016-02-25
申请号：US14463635
申请日：2014-08-19
申请人： REG Life Sciences, LLC
发明人： Myong K. KO , Perry Y. Liao , Simon Li , Fernando A. Sanchez-Riera
IPC分类号： C07C29/86 , C07C31/22
CPC分类号： C07C29/86 , C07C31/225 , C11D19/00
摘要： The disclosure relates to a novel glycerol purification process that produces partially refined waste glycerol for a variety of industrial applications. The disclosure encompasses a salt-containing partially refined glycerol composition that is suitable as a fermentation grade glycerol.

88. 发明授权

US09249076B2 Recyclable extractant compositions 有权
标题翻译：可循环萃取剂组合物
公开(公告)号：US09249076B2
公开(公告)日：2016-02-02
申请号：US14032328
申请日：2013-09-20
申请人： Douglas Robert Anton , Bruce A. Diner , Steven D. Doig
发明人： Douglas Robert Anton , Bruce A. Diner , Steven D. Doig
IPC分类号： C12P21/06 , C12P7/04 , C07C29/86 , C12P7/16
CPC分类号： C07C29/86 , C12P7/04 , C12P7/16 , C12P21/06 , Y02E50/10
摘要： Provided herein are processes comprising providing a fermentation medium comprising a fermentable carbon source, a recombinant microorganism comprising an engineered butanol biosynthetic pathway, and butanol; contacting said fermentation medium with an extractant composition comprising an effective amount of antioxidant or antioxidant-like compound, whereby at least a portion of the butanol in the fermentation medium partitions into the extractant; recovering at least a portion of the butanol and extractant composition from the fermentation medium; recycling the extractant composition recovered in (c) one or more times in the fermentation medium; optionally adjusting the effective amount of antioxidant or antioxidant-like compound in the extractant composition, whereby the rate of oxidation or effect of oxidized products in the recycled extractant composition is substantially reduced and/or avoided such that the extractant composition may be recycled.
摘要翻译：本文提供的方法包括提供包含可发酵碳源的发酵培养基，包含工程丁醇生物合成途径的重组微生物和丁醇; 使所述发酵培养基与包含有效量的抗氧化剂或抗氧化剂样化合物的提取剂组合物接触，由此发酵培养基中的至少一部分丁醇分配到提取剂中; 从发酵培养基中回收至少一部分丁醇和提取剂组合物; 在（c）中回收的萃取剂组合物在发酵培养基中回收一次或多次; 任选地调节萃取剂组合物中抗氧化剂或抗氧化剂样化合物的有效量，从而大大降低和/或避免了再循环的萃取剂组合物中的氧化产物的氧化速率或氧化产物的影响，从而萃取剂组合物可循环使用。

89. 发明申请

US20160002692A1 EXPRESSION OF BETA-GLUCOSIDASES FOR HYDROLYSIS OF LIGNOCELLULOSE AND ASSOCIATED OLIGOMERS 审中-公开
标题翻译：用于水解纤维素和相关寡聚体的β-葡糖苷酶的表达
公开(公告)号：US20160002692A1
公开(公告)日：2016-01-07
申请号：US14772100
申请日：2014-03-13
申请人： LALLEMAND HUNGARY LIQUIDITY MANAGEMENT LLC
发明人： John MCBRIDE , Erin WISWALL
IPC分类号： C12P19/14 , C07C29/86 , C12P7/10 , C12N9/42 , C12P19/02
CPC分类号： C12P19/14 , C07C29/86 , C12N9/2445 , C12P7/10 , C12P19/02 , C12Y302/01021 , Y02E50/16
摘要： The present invention provides for heterologous expression of beta-glucosidase (BGL) polypeptides encoded by Humicola grisea, Candida wickerhamii, Aspergillus aculeatus, Aspergillus oryzae, Penicillium decumbens, Chaetomium globosum, Neocallimastix frontalis, Debaryomyces hansenii, Kluyveromyces marxianus, or Phytophthora infestans in host cells, such as the yeast Saccharomyces cerevisiae. The expression in such host cells of the corresponding genes, and variants and combinations thereof, result in improved specific activity of the expressed BGL. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.
摘要翻译：本发明提供了由Humicola grisea，Wickerhamii，Aspergillus aculeatus，Aspergillus oryzae，Penicillium decumbens，Chaetomium globosum，Neocallimastix frontalis，Debaryomyces hansenii，Kluyveromyces marxianus或致病疫霉在宿主细胞中编码的β-葡糖苷酶（BGL），例如酵母酿酒酵母（Saccharomyces cerevisiae）。相应基因的这种宿主细胞中的表达及其变体和组合导致表达的BGL的改善的比活性。因此，这些基因和表达系统对于有效和成本有效的整合生物处理系统是有用的。

90. 发明申请

US20150376096A1 METHOD FOR PRODUCING BUTANOL USING EXTRACTIVE FERMENTATION 有权
标题翻译：使用提取发酵生产丁醇的方法
公开(公告)号：US20150376096A1
公开(公告)日：2015-12-31
申请号：US14772720
申请日：2014-03-14
申请人： BUTAMAX ADVANCED BIOFUELS LLC
发明人： Douglas Robert ANTON , John W. HALLAM
IPC分类号： C07C29/86
CPC分类号： C07C29/86 , C07C29/76 , C07C31/12 , C12P7/16 , Y02E50/10
摘要： The invention relates to a method for producing butanol through microbial fermentation, in which the butanol product is removed by extraction into a water immiscible organic extractant composition during the fermentation. The invention also relates to a method for producing butanol through microbial fermentation, in which the butanol product is removed during the fermentation by extraction into a water-immiscible extractant composition comprising a first solvent having a butanol partition coefficient of at least 3, and a second solvent having a butanol partition coefficient, wherein the butanol partition coefficient of the first solvent is higher than the butanol partition coefficient of the second solvent. Optionally, the first solvent has a higher concentration of hydrogen bonding sites than the second solvent. The invention further relates to a composition including butanol in the water immiscible organic extractant composition described above.
摘要翻译：本发明涉及通过微生物发酵生产丁醇的方法，其中通过在发酵期间通过萃取到与水不混溶的有机萃取剂组合物中除去丁醇产物。本发明还涉及一种通过微生物发酵生产丁醇的方法，其中在发酵过程中将丁醇产物通过萃取到与水不混溶的萃取剂组合物中除去，该组合物包含具有至少3的丁醇分配系数的第一溶剂和第二溶剂具有丁醇分配系数的溶剂，其中第一溶剂的丁醇分配系数高于第二溶剂的丁醇分配系数。任选地，第一溶剂具有比第二溶剂高的氢键位置浓度。本发明还涉及上述与水不混溶的有机萃取剂组合物中包含丁醇的组合物。

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