专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

81. 发明申请

US20150307680A1 ORGANO-AMINE ACID GAS ADSORPTION-DESORPTION POLYMERS, PROCESES FOR PREPARING SAME, AND USES THEREOF 有权
标题翻译：有机酸酸气体吸收分解聚合物，其制备方法及其用途
公开(公告)号：US20150307680A1
公开(公告)日：2015-10-29
申请号：US14791800
申请日：2015-07-06
申请人： Dennis G. Peiffer, JR. , David C. Calabro , Li Quanchang , Stephen M. Cundy
发明人： Dennis G. Peiffer, JR. , David C. Calabro , Li Quanchang , Stephen M. Cundy
IPC分类号： C08J9/14 , B01D53/02
CPC分类号： B01D53/02 , B01D53/40 , B01D53/62 , B01D2251/80 , B01D2253/202 , B01D2253/311 , B01D2256/24 , B01D2257/504 , B01D2258/0283 , B01J20/262 , B01J20/264 , B01J20/267 , B01J20/28057 , B01J20/28069 , B01J20/28078 , B01J20/3085 , B01J20/3425 , B01J20/3483 , B01J20/3491 , B01J2220/56 , C07C211/53 , C08G73/00 , C08G73/02 , C08G73/0206 , C08J9/141 , C08J9/26 , C08J9/28 , C08J2201/026 , C08J2201/0502 , C08J2203/14 , C08J2379/02 , Y02C10/04 , Y02C10/08 , Y02P20/152 , Y10T428/2982
摘要： An adsorption-desorption material, in particular, crosslinked organo-amine polymeric materials having a weight average molecular weight of from about 500 to about 1×106, a total pore volume of from about 0.2 cubic centimeters per gram (cc/g) to about 2.0 cc/g, and an adsorption capacity of at least about 0.2 millimoles of CO2 adsorbed per gram of adsorption-desorption material, and linear organo-amine polymeric materials having a weight average molecular weight of from about 160 to about 1×106, a total pore volume of from about 0.2 cubic centimeters per gram (cc/g) to about 2.0 cc/g, and an adsorption capacity of at least about 0.2 millimoles of CO2 adsorbed per gram of adsorption-desorption material. This disclosure also relates in part to processes for preparing the crosslinked organo-amine materials and linear organo-amine materials. This disclosure further relates in part to the selective removal of CO2 and/or other acid gases from a gaseous stream containing one or more of these gases using the adsorption-desorption materials.
摘要翻译：吸附解吸材料，特别是重均分子量为约500至约1×10 6的交联有机胺聚合物材料，总孔体积为约0.2立方厘米每克（cc / g）至约 2.0cc / g，每克吸附 - 解吸材料吸附至少约0.2毫摩尔二氧化碳的吸附能力，重均分子量为约160至约1×106的线性有机胺聚合物，总孔体积为约0.2立方厘米每克（cc / g）至约2.0cc / g，吸附能力为每克吸附 - 解吸材料吸附至少约0.2毫摩尔二氧化碳。本公开还部分涉及制备交联的有机胺材料和线性有机胺材料的方法。本公开还部分地涉及使用吸附 - 解吸材料从含有一种或多种这些气体的气流中选择性除去CO 2和/或其它酸性气体。

82. 发明申请

US20150175534A1 Alpha-7 NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS AND USES THEROF-I 审中-公开
标题翻译： α-7 NICOTINIC乙酰胆碱受体调节剂及其用途
公开(公告)号：US20150175534A1
公开(公告)日：2015-06-25
申请号：US14418695
申请日：2013-08-01
申请人： Merck Sharp & Dohme Corp.
发明人： Andrew Harvey , Thomas Avery , Dharam Paul , Justin Ripper , Belinda Huff , Rajinder Singh , Laurent Schaeffer , Christophe Joseph , Christophe Morice , Bruno Giethlen
IPC分类号： C07C311/37 , C07C311/08 , C07D261/14 , C07C303/36 , C07D213/74
CPC分类号： C07C311/37 , C07C211/53 , C07C217/82 , C07C303/36 , C07C307/10 , C07C311/08 , C07C311/30 , C07C311/39 , C07C311/48 , C07C311/49 , C07C2601/02 , C07C2601/14 , C07C2601/16 , C07C2602/50 , C07D213/74 , C07D231/38 , C07D233/72 , C07D237/20 , C07D239/42 , C07D239/47 , C07D241/20 , C07D261/14 , C07D277/42 , C07D295/135 , C07D305/08 , C07F9/58
摘要： The present invention relates to chemical compounds of formula (I), with the substituents as described in the specification, useful in the positive modulation of the alpha 7 nicotinic acetylcholine receptor (α7 nAChR). The invention also relates to the use of these compounds in the treatment or prevention of a broad range of diseases in which the positive modulation of α7 nAChR is advantageous, including neurodegenerative and neuropsychiatric diseases and also neuropathic pain and inflammatory diseases.
摘要翻译：本发明涉及式（I）化合物，其具有说明书中所述的取代基，其用于α7烟碱乙酰胆碱受体（α7nAChR）的阳性调节。本发明还涉及这些化合物在治疗或预防α7nAChR的阳性调节有益的广泛疾病中的用途，包括神经变性和神经精神疾病以及神经性疼痛和炎性疾病。

83. 发明授权

US08821592B1 Oxidation dye precursors 有权
标题翻译：氧化染料前体
公开(公告)号：US08821592B1
公开(公告)日：2014-09-02
申请号：US14234105
申请日：2012-05-29
申请人： Wibke Gross , Ralph Nemitz , Astrid Kroos
发明人： Wibke Gross , Ralph Nemitz , Astrid Kroos
IPC分类号： A61Q5/10 , C07C211/63 , A61K8/49 , C07C211/53 , C07D295/13 , A61K8/41
CPC分类号： A61K8/4946 , A61K8/416 , A61K8/494 , A61Q5/10 , C07C211/53 , C07C211/63 , C07D295/13
摘要： An agent for the oxidative dyeing of keratinous fibers is provided. The agent contains, as a developer-type oxidation dye precursor, a compound of Formula (I) that carries at least one cationic charge in Y.
摘要翻译：提供角质纤维氧化染色剂。作为显影剂型氧化染料前体，该试剂含有在Y中携带至少一种阳离子电荷的式（I）化合物。

84. 发明申请

US20140011857A1 SMALL MOLECULES AS EPIGENETIC MODULATORS OF LYSINE-SPECIFIC DEMETHYLASE 1 AND METHODS OF TREATING DISORDERS 有权
标题翻译：作为特异性脱乙酰酶1的调节剂的小分子和治疗疾病的方法
公开(公告)号：US20140011857A1
公开(公告)日：2014-01-09
申请号：US13821962
申请日：2011-09-12
申请人： Robert A. Casero , Ian Bytheway , Patrick M. Woster
发明人： Robert A. Casero , Ian Bytheway , Patrick M. Woster
IPC分类号： C07C237/16 , C07C335/12 , C07C275/24 , C07C211/53 , C07D209/48
CPC分类号： C07C237/16 , C07C211/53 , C07C259/14 , C07C275/24 , C07C335/12 , C07D209/48
摘要： The invention provides for novel compounds which are inhibitors of lysine-specific demethylase 1 (LSD1). Such compounds may be used to treat disorders, including cancer.
摘要翻译：本发明提供了作为赖氨酸特异性脱甲基酶1（LSD1）的抑制剂的新化合物。这些化合物可用于治疗包括癌症在内的疾病。

85. 发明授权

US08501659B2 Processes for the preparation of arylamine compounds 失效
标题翻译：制备芳基胺化合物的方法
公开(公告)号：US08501659B2
公开(公告)日：2013-08-06
申请号：US13126202
申请日：2009-10-21
申请人： Adam M. Johns
发明人： Adam M. Johns
IPC分类号： B01J31/02 , C07C209/00 , C07C213/08
CPC分类号： B01J31/2295 , C07C209/10 , C07C213/08 , C07C211/53 , C07C217/74
摘要： A process for the preparation of N-arylamine compounds, the process including: reacting a compound having an amino group with an acylating compound in the presence of a base and a transition metal catalyst under reaction conditions effective to form an N-arylamine compound; wherein the transition metal catalyst comprises a complex of a Group 8-10 metal and at least one chelating ligand comprising (R)-(−)-1-[(S)-2-dicyclohexylphosphino]-ferrocenyl]ethyldi-t-butylphosphine.
摘要翻译：一种制备N-芳基胺化合物的方法，该方法包括：在有效形成N-芳基胺化合物的反应条件下，在碱和过渡金属催化剂的存在下使具有氨基的化合物与酰化化合物反应; 其中所述过渡金属催化剂包含第8-10族金属和至少一种包含（R） - （ - ） - 1 - [（S）-2-二环己基膦基] - 二氢呋喃基]乙基二叔丁基膦的螯合配体的络合物。

86. 发明授权

US08431746B2 Method for producing diphenylmethane diamine 有权
标题翻译：二苯甲烷二胺的制备方法
公开(公告)号：US08431746B2
公开(公告)日：2013-04-30
申请号：US12992472
申请日：2009-05-20
申请人： Johannes Jacobs
发明人： Johannes Jacobs
IPC分类号： C07C211/50 , C07C209/82 , C07C209/86
CPC分类号： C07C209/78 , C07C209/84 , C07C211/53
摘要： The invention relates to a process for preparing mixtures of diphenylmethanediamine and polyphenylenepolymethylenepolyamines, which comprises the steps a) reaction of aniline with formaldehyde in the presence of hydrochloric acid, b) neutralization of the reaction mixture formed in step a) c) separation of the organic phase from the aqueous phase, d) work-up of the organic phase, e) work-up of the aqueous phase, wherein step e) comprises at least the steps e1) extraction of the aqueous phase with an organic solvent, e2) stripping of the aqueous phase obtained in step e1), e3) absorption of the solution obtained from step e2).
摘要翻译：本发明涉及一种制备二苯基甲二胺和聚亚苯基多亚甲基多胺的混合物的方法，其包括以下步骤：a）在盐酸存在下苯胺与甲醛反应，b）中和步骤a）中形成的反应混合物，c）分离有机相和水相，d）有机相的后处理，e）水相的后处理，其中步骤e）至少包括步骤e1）用有机溶剂萃取水相，e2）汽提的步骤e1）中获得的水相，e3）从步骤e2）获得的溶液的吸收。

87. 发明授权

US08362311B2 Highly Z-selective olefins metathesis 有权
公开(公告)号：US08362311B2
公开(公告)日：2013-01-29
申请号：US12571036
申请日：2009-09-30
申请人： Richard R. Schrock , Annie J. King , Yu Zhao , Margaret M. Flook , Amir H. Hoveyda
发明人： Richard R. Schrock , Annie J. King , Yu Zhao , Margaret M. Flook , Amir H. Hoveyda
IPC分类号： C07C6/00 , C07F11/00
CPC分类号： B01J31/2295 , B01J31/1805 , B01J31/181 , B01J31/1825 , B01J31/2226 , B01J31/2265 , B01J31/2278 , B01J2231/54 , B01J2231/543 , B01J2531/0266 , B01J2531/0288 , B01J2531/64 , B01J2531/66 , B01J2540/225 , B01J2540/40 , C07B2200/09 , C07C6/04 , C07C41/30 , C07C67/475 , C07C209/64 , C07C209/68 , C07C303/40 , C07C2531/18 , C07C2531/22 , C07C2601/14 , C07C2601/16 , C07C2602/10 , C07F5/025 , C07F7/083 , C07F11/00 , C07F11/005 , C07C13/28 , C07C11/02 , C07C15/50 , C07C43/166 , C07C69/593 , C07C311/18 , C07C211/53
摘要： The present invention relates generally to catalysts and processes for the Z-selective formation of internal olefin(s) from terminal olefin(s) via homo-metathesis reactions.

88. 发明申请

US20120004310A1 NON-PEPTIDE BDNF NEUROTROPHIN MIMETICS 审中-公开
标题翻译：非肽BDNF神经营养因子
公开(公告)号：US20120004310A1
公开(公告)日：2012-01-05
申请号：US13117537
申请日：2011-05-27
申请人： Frank M. LONGO , Stephen M. Massa , Sandeep Gupta
发明人： Frank M. LONGO , Stephen M. Massa , Sandeep Gupta
IPC分类号： A61K31/166 , C07C33/26 , C07C33/30 , C07C43/23 , C07C237/34 , C07C233/78 , C07C215/68 , C07D211/42 , C07D295/135 , C07D215/20 , A61K31/047 , A61K31/09 , A61P25/28 , A61P25/00 , A61P25/08 , A61P25/16 , A61P9/10 , A61P25/24 , A61P3/00 , A61P3/04 , A61P29/00 , A61P35/00 , C12N5/071 , C12N5/0793 , C07C327/48
CPC分类号： C07C33/30 , A61K31/136 , C07C33/26 , C07C33/46 , C07C43/2055 , C07C43/23 , C07C211/53 , C07C215/16 , C07C215/68 , C07C215/70 , C07C215/74 , C07C233/78 , C07C237/34 , C07C237/42 , C07C327/48 , C07C2601/14 , C07D211/42 , C07D215/14 , C07D215/20 , C07D295/135 , C07D401/10
摘要： Methods and compounds for treating neurological and other disorders are provided. Included is the administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for a TrkB receptor molecule.
摘要翻译：提供了治疗神经系统疾病和其他疾病的方法和化合物。包括向有需要的受试者施用有效量的对TrkB受体分子具有结合和/或调节特异性的化合物。

89. 发明申请

US20110065960A1 METHOD FOR PRODUCING DIPHENYLMETHANE DIAMINE 有权
标题翻译：生产二苯基甲烷二胺的方法
公开(公告)号：US20110065960A1
公开(公告)日：2011-03-17
申请号：US12992472
申请日：2009-05-20
申请人： Johannes Jacobs
发明人： Johannes Jacobs
IPC分类号： C07C211/50
CPC分类号： C07C209/78 , C07C209/84 , C07C211/53
摘要： The invention relates to a process for preparing mixtures of diphenylmethanediamine and polyphenylenepolymethylenepolyamines, which comprises the stepsa) reaction of aniline with formaldehyde in the presence of hydrochloric acid,b) neutralization of the reaction mixture formed in step a)c) separation of the organic phase from the aqueous phase,d) work-up of the organic phase,e) work-up of the aqueous phase,wherein step e) comprises at least the stepse1) extraction of the aqueous phase with an organic solvent,e2) stripping of the aqueous phase obtained in step e1),e3) absorption of the solution obtained from step e2).
摘要翻译：本发明涉及一种制备二苯基甲二胺和聚亚苯基多亚甲基多胺的混合物的方法，其包括以下步骤：a）在盐酸存在下苯胺与甲醛反应，b）中和步骤a）中形成的反应混合物，c）分离有机相和水相，d）有机相的后处理，e）水相的后处理，其中步骤e）至少包括步骤e1）用有机溶剂萃取水相，e2）汽提的步骤e1）中获得的水相，e3）从步骤e2）获得的溶液的吸收。

90. 发明申请

US20080317806A1 Antiparasitic Compounds 审中-公开
标题翻译：抗寄生虫化合物
公开(公告)号：US20080317806A1
公开(公告)日：2008-12-25
申请号：US11911099
申请日：2006-04-11
申请人： Wayne Morris Best , Colette Gloria Sims , Richard Christopher Andrew Thompson , Simon Andrew Reid , Anthony Armson , James Alexander Reynoldson
发明人： Wayne Morris Best , Colette Gloria Sims , Richard Christopher Andrew Thompson , Simon Andrew Reid , Anthony Armson , James Alexander Reynoldson
IPC分类号： A61F2/04 , C07D241/04 , A61K31/495 , C07D265/30 , A61K31/5375 , C07C211/46 , A61P33/00 , A61K31/136 , A61K31/54 , C07D279/12 , A61K9/12
CPC分类号： C07C211/52 , C07C211/53 , C07C217/58 , C07C2601/08 , C07C2601/14 , C07C2603/74 , C07D207/14 , C07D207/16 , C07D211/22 , C07D211/42 , C07D211/44 , C07D235/08 , C07D235/30 , C07D239/42 , C07D295/073 , C07D295/088 , C07D295/26 , C07D295/30 , C07D403/04
摘要： A compound of Formula (A), wherein R1 is C1-C5 alkyl, C3-C6 branched alkyl, C4-C7 cycloalkyl, C8-C12 fused or bridged polycycloalkyl, or heterocyclic ring, where any of the preceding alkyl, cycloalkyl or heterocyclic ring groups may be singly or multiply substituted with X; R2 is H or R1; and X is halo, carbonyl carboxylic acid, carboxylic ester, carboxamide, substituted carboxamide, hydroxy, alkoxy, thioalkyl, sulphoxide, sulphone, sulphonamide, substituted sulphonamide, phenoxy, substituted phenoxy, phenyl, substituted phenyl, amino, substituted amino (including quaternary ammonium salts), N-oxide, imino, 5-7 membered heterocycle, or substituted heterocycle.
摘要翻译：式（A）的化合物，其中R 1是C 1 -C 5烷基，C 3 -C 6支链烷基，C 4 -C 7环烷基，C 8 -C 12稠合或桥连多环烷基或杂环，其中任何前述烷基，环烷基或杂环基团可以单独或多重被X取代; R2是H或R1; 羟基，烷氧基，硫代烷基，亚砜，砜，磺酰胺，取代的磺酰胺，苯氧基，取代的苯氧基，苯基，取代的苯基，氨基，取代的氨基（包括季铵盐），N-氧化物，亚氨基，5-7元杂环或取代的杂环。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式