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81. 发明申请

US20160003760A1 Electrochemical Sensor Chip 有权
标题翻译：电化学传感器芯片
公开(公告)号：US20160003760A1
公开(公告)日：2016-01-07
申请号：US14325219
申请日：2014-07-07
申请人： Google Inc.
发明人： James Etzkorn
IPC分类号： G01N27/30 , A61B5/145
CPC分类号： A61B5/14507 , A61B5/0537 , A61B5/14532 , A61B5/1477 , A61B5/6821 , A61B5/742 , A61B2560/0468 , A61B2562/125 , G02C7/04 , G02C11/10
摘要： An electrochemical sensor is disposed on a sensor substrate suitable for flip-chip mounting to another substrate. The electrochemical sensor can be fabricated in bulk by patterning sets of electrodes on a common substrate with vias that electrically couple each electrode to a conductive pad on the opposite side of the substrate. The substrate with electrodes thereon can then be diced and the individual electrochemical sensors can be flip-chip mounted in a body-mountable device in which the sensor can be used to obtain analyte concentrations. As a result, fabrication of the electrochemical sensor electrodes can be isolated from fabrication of the other electronics in the device, which can facilitate efficient fabrication of the sensor and allows for other electronics to be fabricated without restrictions associated with the electrode fabrication.
摘要翻译：电化学传感器设置在适于倒装芯片安装到另一基板的传感器基板上。电化学传感器可以通过在具有通孔的共同衬底上图案化组的电极来大量制造，该过孔将每个电极电耦合到衬底的相对侧上的导电焊盘。然后可以对其上具有电极的基板进行切割，并且可以将各个电化学传感器倒装安装在体内安装的装置中，其中传感器可用于获得分析物浓度。结果，电化学传感器电极的制造可以与器件中的其它电子器件的制造隔离开来，这可以促进传感器的有效制造，并允许制造其它电子器件，而不受与电极制造相关的限制。

82. 发明授权

US09220420B2 Implantable dielectrometer 有权
标题翻译：可植入介电电感
公开(公告)号：US09220420B2
公开(公告)日：2015-12-29
申请号：US13811217
申请日：2011-07-21
申请人： Uriel Weinstein , Assaf Bernstein , Eyal Cohen , Dov Oppenheim , Moshe Mosesko
发明人： Uriel Weinstein , Assaf Bernstein , Eyal Cohen , Dov Oppenheim , Moshe Mosesko
IPC分类号： A61B5/0205 , A61B5/00 , A61B5/05 , A61N1/375 , A61B5/053 , A61B5/01 , A61B5/0215 , A61B5/042 , A61B5/145 , A61N1/365 , A61N1/37 , A61N1/372
CPC分类号： A61B5/0538 , A61B1/313 , A61B5/0028 , A61B5/0031 , A61B5/0059 , A61B5/01 , A61B5/0205 , A61B5/0215 , A61B5/0422 , A61B5/05 , A61B5/0537 , A61B5/076 , A61B5/0809 , A61B5/14542 , A61B5/416 , A61B5/4244 , A61B5/4552 , A61B5/4875 , A61B5/6833 , A61B5/686 , A61B5/72 , A61B17/3468 , A61B2560/0219 , A61B2562/0214 , A61B2562/164 , A61N1/36521 , A61N1/3702 , A61N1/37229 , A61N1/3756
摘要： Diagnostic apparatus (24) includes a sealed case (80), comprising a biocompatible material and configured for implantation within a body of a human subject (22). A dielectrometric probe (26, 50, 63, 66, 70, 102, 160) is connected to the case and includes first and second conductors (40, 42, 54, 56, 64, 67, 68, 72, 74, 162, 164), which are configured to be placed in proximity to a target tissue (34) in the body. A driving circuit (82), which is contained in the case, is coupled to apply a radio-frequency (RF) signal to the probe and to sense the signal returned from the probe. Processing circuitry (84) is configured to evaluate, responsively to the returned signal, a dielectric property of the target tissue.
摘要翻译：诊断装置（24）包括密封壳体（80），其包括生物相容性材料并被构造用于植入人体受试者体内（22）。介电测量探针（26,50,63,66,70,102,160）连接到壳体，并包括第一和第二导体（40,42,54,56,64,67,68,72,74,162， 164），其被配置为放置在身体中靠近目标组织（34）的位置。包含在壳体中的驱动电路（82）被耦合以将射频（RF）信号施加到探头并感测从探针返回的信号。处理电路（84）被配置为响应于所返回的信号来评估目标组织的介电性质。

83. 发明申请

US20150359486A1 DEVICE AND METHOD HAVING AUTOMATIC USER-RESPONSIVE AND USER-SPECIFIC PHYSIOLOGICAL-METER PLATFORM 审中-公开
标题翻译：具有自动用户响应和用户特定生理平台平台的设备和方法
公开(公告)号：US20150359486A1
公开(公告)日：2015-12-17
申请号：US14338266
申请日：2014-07-22
申请人： PhysioWave, Inc.
发明人： Gregory T. Kovacs , Laurent B. Giovangrandi , Robert Bruce Darling
IPC分类号： A61B5/00 , A61B5/0408 , A61B5/04 , A61B5/0205 , A61B5/044 , A61B5/11 , A61B5/0295 , G01R27/02 , A61B5/0432
CPC分类号： A61B5/0245 , A61B5/0205 , A61B5/024 , A61B5/02444 , A61B5/0295 , A61B5/04012 , A61B5/0408 , A61B5/0535 , A61B5/0537 , A61B5/1102 , A61B5/1113 , A61B5/6844 , A61B5/72 , A61B5/74 , A61B2560/0209 , A61B2576/00 , G01G19/50 , G01R27/02
摘要： Aspects of the present disclosure are directed to a CPU and a memory circuit that has user-corresponding data stored on the memory circuit, and a platform over which a plurality of electrodes are interleaved, and configured for engaging the user. While the plurality of electrodes is concurrently contacting a limb or other extremity of the user, measurement signals are obtained from the plurality of electrodes. Based on a plurality of impedance-measurement signals being obtained from the electrodes, signals are generated that correspond to cardiovascular timings specific to the user. In such aspects of the present disclosure, pulse characteristic signals are determined based on the plurality of impedance-measurement signals and comparisons of user-obtained data are made relative to user-data profiles stored in the memory circuit.
摘要翻译：本公开的方面涉及具有存储在存储器电路上的用户对应数据的CPU和存储器电路，以及多个电极交错的平台，并且被配置为接合用户。当多个电极同时接触用户的肢体或其他肢体时，从多个电极获得测量信号。基于从电极获得的多个阻抗测量信号，产生对应于用户特有的心血管定时的信号。在本公开的这些方面中，基于多个阻抗测量信号确定脉冲特征信号，并且相对于存储在存储器电路中的用户数据简档进行用户获得的数据的比较。

84. 发明申请

US20150351660A1 ABSOLUTE THORACIC IMPEDANCE FOR HEART FAILURE RISK STRATIFICATION 审中-公开
标题翻译：心脏衰竭危险分析的绝对胸外阻力
公开(公告)号：US20150351660A1
公开(公告)日：2015-12-10
申请号：US14711020
申请日：2015-05-13
申请人： Cardiac Pacemakers, Inc.
发明人： Qi An , Pramodsingh Hirasingh Thakur , Ramesh Wariar
IPC分类号： A61B5/053 , A61B5/00 , A61B5/08 , A61B5/0205 , A61B7/04
CPC分类号： A61B5/0535 , A61B5/0205 , A61B5/0537 , A61B5/0538 , A61B5/0809 , A61B5/6823 , A61B5/6852 , A61B5/7275 , A61B7/04 , A61N1/362 , A61N1/36521 , G16H50/30
摘要： An apparatus may include a sensing circuit configured to generate a sensed physiological signal representative of thoracic impedance of a subject and a controller circuit. The a controller circuit is electrically coupled to the sensing circuit and includes a measurement circuit that determines a measure of absolute thoracic impedance using the sensed physiological signal, and a risk circuit that quantifies a risk of worsening heart failure (WHF) for the subject using a comparison of the determined measure of absolute thoracic impedance to a specified threshold value of absolute thoracic impedance, and generate an indication of risk of WHF of the subject according to the quantifying of the risk.
摘要翻译：一种装置可以包括感测电路，其被配置为产生代表对象的胸部阻抗的感测生理信号和控制器电路。控制器电路电耦合到感测电路并且包括使用感测到的生理信号确定绝对胸部阻抗的量度的测量电路，以及风险电路，其使用以下方法量化对象的心力衰竭（WHF）恶化的风险将确定的绝对胸阻抗测量与绝对胸阻抗的指定阈值进行比较，并根据风险的量化产生受试者的WHF风险指标。

85. 发明申请

US20150342539A1 METHOD AND APPARATUS FOR USE IN MONITORING AND IDENTIFYING ABNORMAL VALUES OF A PHYSIOLOGICAL CHARACTERISTIC OF A SUBJECT 审中-公开
标题翻译：用于监测和识别受试者生理特征异常值的方法和装置
公开(公告)号：US20150342539A1
公开(公告)日：2015-12-03
申请号：US14647832
申请日：2013-12-11
申请人： KONINKLIJKE PHILIPS N.V.
发明人： Tine SMITS , Jennifer CAFFAREL , Emile Josephus Carlos KELKBOOM
IPC分类号： A61B5/00 , A61B5/08 , A61B5/053
CPC分类号： A61B5/7282 , A61B5/00 , A61B5/053 , A61B5/0537 , A61B5/08 , A61B5/0809 , A61B5/4878 , A61B5/7246
摘要： There is provided a method for use in monitoring a physiological characteristic of a subject, the method comprising receiving a value of the physiological characteristic of the subject; determining whether the received physiological characteristic value is normal using a range of normal variability of the physiological characteristic for the subject calculated using a set of previous values of the physiological characteristic for the subject; and in the event that the received physiological characteristic value is determined to be normal, updating the range of normal variability using the received physiological characteristic value.
摘要翻译：提供了一种用于监测受试者的生理特征的方法，所述方法包括接收受试者的生理特征的值; 使用所述对象的生理特征的一组先前值计算的所述对象的生理特征的正常变异范围来确定所接收的生理特征值是否正常; 并且在接收到的生理特征值被确定为正常的情况下，使用所接收的生理特征值来更新正常变异性的范围。

86. 发明申请

US20150335256A1 MULTI-SENSOR PATIENT MONITOR TO DETECT IMPENDING CARDIAC DECOMPENSATION 有权
标题翻译：多传感器患者监测器检测进行心脏衰竭
公开(公告)号：US20150335256A1
公开(公告)日：2015-11-26
申请号：US14814879
申请日：2015-07-31
申请人： Medtronic Monitoring, Inc.
发明人： Imad LIBBUS , Mark J. BLY , Kristofer J. JAMES , Scott T. MAZAR , Jerry S. WANG
IPC分类号： A61B5/02 , A61B5/0205 , A61B5/024 , A61B5/11 , A61B5/0408 , A61B5/044 , A61B5/0452 , A61B5/053 , A61B5/00 , A61B5/04
CPC分类号： A61B5/02028 , A61B5/0002 , A61B5/0004 , A61B5/0006 , A61B5/0008 , A61B5/01 , A61B5/02055 , A61B5/02405 , A61B5/0245 , A61B5/04012 , A61B5/04085 , A61B5/04087 , A61B5/044 , A61B5/0452 , A61B5/0531 , A61B5/0535 , A61B5/0537 , A61B5/08 , A61B5/0816 , A61B5/1114 , A61B5/1116 , A61B5/1118 , A61B5/443 , A61B5/4875 , A61B5/6833 , A61B5/6843 , A61B5/6885 , A61B5/7264 , A61B5/7275 , A61B5/7282 , A61B5/746 , A61B2560/0412 , A61B2560/0468 , A61B2562/0209 , A61B2562/0214 , A61B2562/043 , A61B2562/164 , G06F19/00 , G06F19/3418 , G16H50/30
摘要： A system for detecting impending acute cardiac decompensation of a patient includes impedance circuitry, an activity sensor, and a processor system. The impedance circuitry measures a hydration signal of the patient, wherein the hydration signal corresponds to a tissue hydration of the patient. The activity sensor to measure an activity level of the patient, and the processor system includes a computer readable memory in communication with the impedance circuitry and the activity sensor, wherein the computer readable memory of the processor system embodies instructions to combine the hydration signal and the activity level of the patient to detect the impending acute cardiac decompensation.
摘要翻译：用于检测患者即将到来的急性心脏代偿失调的系统包括阻抗电路，活动传感器和处理器系统。阻抗电路测量患者的水合信号，其中水合信号对应于患者的组织水合。用于测量患者的活动水平的活动传感器和处理器系统包括与阻抗电路和活动传感器通信的计算机可读存储器，其中处理器系统的计算机可读存储器体现指令以组合水合信号和患者的活动水平检测即将发生的急性心脏失代偿。

87. 发明授权

US09192321B2 Apparatus for measuring body fat 有权
标题翻译：用于测量身体脂肪的装置
公开(公告)号：US09192321B2
公开(公告)日：2015-11-24
申请号：US13581586
申请日：2011-03-24
申请人： Hiroaki Fukuda , Tatsuya Takahashi , Yoshie Terazono
发明人： Hiroaki Fukuda , Tatsuya Takahashi , Yoshie Terazono
IPC分类号： A61B5/053 , A61B5/00
CPC分类号： A61B5/0537 , A61B5/4872 , A61B5/6823 , Y10T29/49002
摘要： A body fat measurement apparatus is disclosed. The apparatus includes a current-applying electrode pair including two electrodes for applying a current, and a voltage-measuring electrode pair including two electrodes for measuring a voltage. The current-applying electrode pair is provided in such a way that a line which joins the two current-applying electrodes is inclined with respect to a trunk axis of a body to be measured. The voltage-measuring electrode pair is provided between the two current-applying electrodes.
摘要翻译：公开了一种身体脂肪测量装置。该装置包括：电流施加电极对，其包括用于施加电流的两个电极;以及包括用于测量电压的两个电极的电压测量电极对。电流施加电极对以这样的方式设置，使得连接两个电流施加电极的线相对于待测量的主体的躯干轴线倾斜。电压测量电极对设置在两个电流施加电极之间。

88. 发明授权

US09168001B2 Adhesively mounted apparatus for determining physiological and contextual status 有权
标题翻译：用于确定生理和情境状态的粘合装置
公开(公告)号：US09168001B2
公开(公告)日：2015-10-27
申请号：US14058563
申请日：2013-10-21
申请人： BodyMedia, Inc.
发明人： John M. Stivoric , Scott K. Boehmke , Eric Teller , Christopher Kasabach
IPC分类号： A61B5/02 , A61B5/00 , A61B5/0205 , A61B5/024 , A61B5/053 , A61B5/145 , A61B5/01 , A61B5/0408 , A61B5/11 , A61B5/1468 , A61B7/04
CPC分类号： A61B5/02055 , A61B5/0022 , A61B5/0059 , A61B5/0082 , A61B5/01 , A61B5/0205 , A61B5/022 , A61B5/02405 , A61B5/02438 , A61B5/0402 , A61B5/0408 , A61B5/0476 , A61B5/0488 , A61B5/0533 , A61B5/0537 , A61B5/0816 , A61B5/1102 , A61B5/1118 , A61B5/145 , A61B5/14532 , A61B5/14542 , A61B5/1468 , A61B5/165 , A61B5/411 , A61B5/4519 , A61B5/4809 , A61B5/4866 , A61B5/6802 , A61B5/6804 , A61B5/681 , A61B5/6824 , A61B5/6831 , A61B5/6832 , A61B5/7207 , A61B5/7275 , A61B5/7278 , A61B5/7282 , A61B5/742 , A61B5/7445 , A61B5/7455 , A61B5/7475 , A61B7/04 , A61B2560/0242 , A61B2560/0252 , A61B2560/0295 , A61B2562/0219 , A61B2562/08 , G06F19/00 , G16H40/67
摘要： The invention comprises an apparatus for determining the contextual or physiological status of the individual wearing the apparatus. The apparatus is designed to be consumable or disposable. In most embodiments the invention comprises an adhesive housing. In some embodiments, two different sensors are secured to the housing. The apparatus is in electronic communication with a processing unit that can derive analytical status data by using the data received from the two sensors. In some embodiments, the processing unit is programmed to control other devices, or is programmed to trigger an event. In still other embodiments, the apparatus is in electronic communication with a separate computing device, which may contain the processing unit.
摘要翻译：本发明包括一种用于确定佩戴该装置的个体的情境或生理状况的装置。该设备被设计为可消耗的或一次性的。在大多数实施例中，本发明包括粘合剂外壳。在一些实施例中，两个不同的传感器固定到壳体。该装置与处理单元进行电子通信，处理单元可以通过使用从两个传感器接收的数据来导出分析状态数据。在一些实施例中，处理单元被编程为控制其他设备，或被编程以触发事件。在其他实施例中，该设备与可以包含处理单元的单独的计算设备进行电子通信。

89. 发明申请

US20150294077A1 APPARATUS, SYSTEM, AND METHOD TO ADAPTIVELY OPTIMIZE POWER DISSIPATION AND BROADCAST POWER IN A POWER SOURCE FOR A COMMUNICATION DEVICE 有权
标题翻译：用于通信设备的电源中优化功率放大和广播功率的装置，系统和方法
公开(公告)号：US20150294077A1
公开(公告)日：2015-10-15
申请号：US14435240
申请日：2013-10-15
申请人： PROTEUS DIGITAL HEALTH INC.
发明人： Nilay Jani , Douglas Webb , Jonathan Withrington , Jeffrey Berkman , Haifeng Li
IPC分类号： G06F19/00 , H04B17/21
CPC分类号： G16H40/40 , A61B5/0537 , A61B5/073 , A61B5/4848 , A61B5/6861 , A61B2560/0214 , G06F19/3462 , H04B1/1607 , H04B17/21 , H04L25/4902 , H04N21/4436
摘要： Provided is an apparatus, system, and method for stabilizing battery voltage of a battery device while optimizing power delivered to a receiver during communication of a broadcast packet. A logic circuit is configured to receive a broadcast packet having a predetermined number of bits for communication by a controller to a receiver located remotely from the controller, determine a number of cycles in which a sampled battery voltage is either greater than or less than or equal to a nominal battery voltage over a first subset of the predetermined number of bits of the broadcast packet and performs either a tune-up or a tune-down procedure based on the number of cycles counted in which the sampled battery voltage is not equal to the nominal battery voltage for more than one half of a total number of cycles counted.
摘要翻译：提供一种用于在广播分组的通信期间优化传送到接收机的功率的同时稳定电池装置的电池电压的装置，系统和方法。逻辑电路被配置为接收具有预定数量位的广播分组，用于通过控制器与位于远离控制器的接收机进行通信，确定采样的电池电压大于或小于或等于的周期数到达广播包的预定数目的比特的第一子集上的标称电池电压，并且基于所计数的周期数来执行调谐或调谐过程，其中采样的电池电压不等于标称电池电压超过计数的总循环次数的一半以上。

90. 发明授权

US09149235B2 Oedema detection 有权
标题翻译：水肿检测
公开(公告)号：US09149235B2
公开(公告)日：2015-10-06
申请号：US14136463
申请日：2013-12-20
申请人： Impedimed Limited
发明人： Leigh Ward , Brian Cornish
IPC分类号： A61B5/00 , A61B5/053
CPC分类号： A61B5/7225 , A61B5/0537 , A61B5/4869 , A61B5/4878
摘要： A method of detecting tissue oedema in a subject. The method includes determining a measured impedance for first and second body segments. An index indicative of a ratio of the extra-cellular to intra-cellular fluid is then calculated for each body segment, with these being used to determine an index ratio based on the index for the first and second body segments. The index ration can in turn be used to determine the presence, absence or degree of tissue oedema, for example by comparing the index ratio to a reference or previously determined index ratios.
摘要翻译：一种检测受试者组织水肿的方法。该方法包括确定第一和第二主体段的测量阻抗。然后针对每个身体部分计算指示细胞外细胞液体与细胞内液体的比率的指标，其中这些指数用于基于第一和第二身体段的指数来确定指数比率。指数比例又可用于确定组织水肿的存在，不存在或程度，例如通过将指数比与参考或预先确定的指数比进行比较。

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